benzimidazole has been researched along with Chagas Disease in 6 studies
1H-benzimidazole : The 1H-tautomer of benzimidazole.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of the greatest concerns in Chagas' disease is the absence of reliable methods for the evaluation of chemotherapy efficacy in treated patients." | 1.32 | Use of the Trypanosoma cruzi recombinant complement regulatory protein to evaluate therapeutic efficacy following treatment of chronic chagasic patients. ( Chiari, E; Galvão, LM; Gontijo, ED; Machado-Coelho, GL; Meira, WS; Norris, KA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Beltran-Hortelano, I | 1 |
| Alcolea, V | 1 |
| Font, M | 1 |
| Pérez-Silanes, S | 1 |
| Boiani, M | 1 |
| Boiani, L | 1 |
| Merlino, A | 1 |
| Hernández, P | 1 |
| Chidichimo, A | 1 |
| Cazzulo, JJ | 1 |
| Cerecetto, H | 1 |
| González, M | 1 |
| Díaz-Chiguer, DL | 1 |
| Márquez-Navarro, A | 1 |
| Nogueda-Torres, B | 1 |
| de la Luz León-Ávila, G | 1 |
| Pérez-Villanueva, J | 1 |
| Hernández-Campos, A | 1 |
| Castillo, R | 1 |
| Ambrosio, JR | 1 |
| Nieto-Meneses, R | 1 |
| Yépez-Mulia, L | 1 |
| Hernández-Luis, F | 1 |
| Meira, WS | 1 |
| Galvão, LM | 1 |
| Gontijo, ED | 1 |
| Machado-Coelho, GL | 1 |
| Norris, KA | 1 |
| Chiari, E | 1 |
| Riera, C | 1 |
| Guarro, A | 1 |
| Kassab, HE | 1 |
| Jorba, JM | 1 |
| Castro, M | 1 |
| Angrill, R | 1 |
| Gállego, M | 1 |
| Fisa, R | 1 |
| Martin, C | 1 |
| Lobato, A | 1 |
| Portús, M | 1 |
| Forés, R | 1 |
| Sanjuán, I | 1 |
| Portero, F | 1 |
| Ruiz, E | 1 |
| Regidor, C | 1 |
| López-Vélez, R | 1 |
| Linares, M | 1 |
| Gil, S | 1 |
| Ojeda, E | 1 |
| Krsnik, I | 1 |
| Bautista, G | 1 |
| Vallejo, C | 1 |
| García-Marco, J | 1 |
| Fernández, MN | 1 |
| Cabrera, JR | 1 |
1 review available for benzimidazole and Chagas Disease
| Article | Year |
|---|---|
The role of imidazole and benzimidazole heterocycles in Chagas disease: A review.
Topics: Animals; Benzimidazoles; Chagas Disease; Drug Discovery; Humans; Imidazoles | 2020 |
5 other studies available for benzimidazole and Chagas Disease
| Article | Year |
|---|---|
Second generation of 2H-benzimidazole 1,3-dioxide derivatives as anti-trypanosomatid agents: synthesis, biological evaluation, and mode of action studies.
Topics: Animals; Benzimidazoles; Cell Line; Cell Survival; Chagas Disease; Glucose; Leishmania braziliensis; | 2009 |
In vitro and in vivo trypanocidal activity of some benzimidazole derivatives against two strains of Trypanosoma cruzi.
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Cell Survival; Chagas Disease; Chlorocebus aethiops; | 2012 |
Use of the Trypanosoma cruzi recombinant complement regulatory protein to evaluate therapeutic efficacy following treatment of chronic chagasic patients.
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Brazil; Chagas Disease; DNA, Protozoan; Enzyme-Linked | 2004 |
Congenital transmission of Trypanosoma cruzi in Europe (Spain): a case report.
Topics: Adult; Animals; Benzimidazoles; Cesarean Section; Chagas Disease; Female; Humans; Infant, Newborn; I | 2006 |
Chagas disease in a recipient of cord blood transplantation.
Topics: Adult; Benzimidazoles; Chagas Disease; Cord Blood Stem Cell Transplantation; Fatal Outcome; Graft vs | 2007 |