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benzimidazole and Carcinoma, Hepatocellular

benzimidazole has been researched along with Carcinoma, Hepatocellular in 5 studies

1H-benzimidazole : The 1H-tautomer of benzimidazole.

Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.

Research Excerpts

ExcerptRelevanceReference
"Hepatocellular carcinoma was the most sensitive cell line towards the tested compounds and 8e was the most potent one on HepG2 cells with an IC50 value of 5."5.51Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma. ( Dadashpour, S; Ercan, A; Hosseinimehr, SJ; Irannejad, H; Küçükkılınç, TT; Naderi, N, 2019)
"Hepatocellular carcinoma was the most sensitive cell line towards the tested compounds and 8e was the most potent one on HepG2 cells with an IC50 value of 5."1.51Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma. ( Dadashpour, S; Ercan, A; Hosseinimehr, SJ; Irannejad, H; Küçükkılınç, TT; Naderi, N, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dadashpour, S1
Küçükkılınç, TT1
Ercan, A1
Hosseinimehr, SJ1
Naderi, N1
Irannejad, H1
Suk, FM1
Liu, CL1
Hsu, MH1
Chuang, YT1
Wang, JP1
Liao, YJ1
Xie, Q1
Liu, S1
Li, X1
Wu, Q1
Luo, Z1
Fu, X1
Cao, W1
Lan, G1
Li, D2
Zheng, W1
Chen, T1
Song, WJ1
Lin, QY1
Jiang, WJ1
Du, FY1
Qi, QY1
Wei, Q1
Liu, L1
Zhang, H1
Meng, X1
Yin, J1
Liu, C1

Other Studies

5 other studies available for benzimidazole and Carcinoma, Hepatocellular

ArticleYear
Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:17

    Topics: Antineoplastic Agents; Benzimidazoles; Benzoxazoles; Carcinoma, Hepatocellular; Cell Proliferation;

2019
Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma.
    Scientific reports, 2019, 11-21, Volume: 9, Issue:1

    Topics: Animals; Benzimidazoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferat

2019
Dinuclear zinc(II) complexes containing (benzimidazol-2-yl)benzene that overcome drug resistance in hepatocellular carcinoma cells through induction of mitochondria fragmentation.
    Dalton transactions (Cambridge, England : 2003), 2014, May-21, Volume: 43, Issue:19

    Topics: Adenosine Triphosphate; Apoptosis; Benzene; Benzimidazoles; Carcinoma, Hepatocellular; Coordination

2014
Synthesis, interaction with DNA and antiproliferative activities of two novel Cu(II) complexes with norcantharidin and benzimidazole derivatives.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Feb-25, Volume: 137

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma,

2015
Dinuclear metal(II) complexes of polybenzimidazole ligands as carriers for DNA delivery.
    Biomaterials, 2010, Volume: 31, Issue:6

    Topics: Benzimidazoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Cobalt; Copper; DNA; Drug Carriers; Hum

2010