benzimidazole has been researched along with Breast Cancer in 14 studies
1H-benzimidazole : The 1H-tautomer of benzimidazole.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Breast cancer activity towards MDA-MB-231 and MCF-7 cell lines by inhibiting EGFR was revealed by a novel 2-arylbenzimidazole." | 8.02 | Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti- Breast Cancer (MDA-MB-231, MCF-7) Agents. ( Dimov, S; Mavrova, AT; Nikolova, B; Tsoneva, I; Yancheva, D, 2021) |
| "Three new series of 2-phenyl benzimidazole-based derivatives were designed, synthesized, and evaluated for their in vitro cytotoxic activity against breast cancer (MCF-7) cell lines." | 7.91 | Design and synthesis of 2-phenyl benzimidazole derivatives as VEGFR-2 inhibitors with anti-breast cancer activity. ( Elmorsy, MA; Gomaa, RM; Mostafa, AS, 2019) |
| "Analysis of the primary breast cancer cell lines with HER2 overexpression further confirmed that 5a significantly inhibited Akt Ser473 and Bad Ser136 phosphorylation and reduced cyclin D3 expression." | 5.42 | A benzimidazole derivative exhibiting antitumor activity blocks EGFR and HER2 activity and upregulates DR5 in breast cancer cells. ( Chen, K; Chu, B; Ding, C; Jiang, Y; Li, L; Liu, F; Shen, Z; Sun, Q; Tan, C; Tan, Y, 2015) |
| "The benzimidazole analogues were characterised using (1)H NMR, (13)C NMR, high resolution MS and melting points." | 5.39 | Microwave-assisted synthesis of sec/tert-butyl 2-arylbenzimidazoles and their unexpected antiproliferative activity towards ER negative breast cancer cells. ( Abd Hamid, S; Abdul Rahim, AS; Arumugam, N; Keat, WB; Mat, Ib; Muttiah, NN; Osman, H; Pin, LC; Salhimi, SM; Yee, NS, 2013) |
| " Breast cancer activity towards MDA-MB-231 and MCF-7 cell lines by inhibiting EGFR was revealed by a novel 2-arylbenzimidazole." | 4.02 | Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti- Breast Cancer (MDA-MB-231, MCF-7) Agents. ( Dimov, S; Mavrova, AT; Nikolova, B; Tsoneva, I; Yancheva, D, 2021) |
| "Three new series of 2-phenyl benzimidazole-based derivatives were designed, synthesized, and evaluated for their in vitro cytotoxic activity against breast cancer (MCF-7) cell lines." | 3.91 | Design and synthesis of 2-phenyl benzimidazole derivatives as VEGFR-2 inhibitors with anti-breast cancer activity. ( Elmorsy, MA; Gomaa, RM; Mostafa, AS, 2019) |
| "Four Pt(II) complexes with 2-H/or-methyl/or-aminomethylbenzimidazole or 1,2-dimethylbenzimidazole ligands as "non-leaving groups" were synthesized and their antiproliferative properties were tested against the human MCF-7 breast cancer cell line." | 3.72 | Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum(II) complexes with 2-substituted benzimidazole ligands. ( Algül, O; Diril, N; Eren, G; Eroğlu, H; Gümüş, F; Gür, S; Ozkul, A, 2003) |
| "Analysis of the primary breast cancer cell lines with HER2 overexpression further confirmed that 5a significantly inhibited Akt Ser473 and Bad Ser136 phosphorylation and reduced cyclin D3 expression." | 1.42 | A benzimidazole derivative exhibiting antitumor activity blocks EGFR and HER2 activity and upregulates DR5 in breast cancer cells. ( Chen, K; Chu, B; Ding, C; Jiang, Y; Li, L; Liu, F; Shen, Z; Sun, Q; Tan, C; Tan, Y, 2015) |
| "The benzimidazole analogues were characterised using (1)H NMR, (13)C NMR, high resolution MS and melting points." | 1.39 | Microwave-assisted synthesis of sec/tert-butyl 2-arylbenzimidazoles and their unexpected antiproliferative activity towards ER negative breast cancer cells. ( Abd Hamid, S; Abdul Rahim, AS; Arumugam, N; Keat, WB; Mat, Ib; Muttiah, NN; Osman, H; Pin, LC; Salhimi, SM; Yee, NS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Dimov, S | 1 |
| Mavrova, AT | 1 |
| Yancheva, D | 1 |
| Nikolova, B | 1 |
| Tsoneva, I | 1 |
| Paul, A | 1 |
| Singh, P | 1 |
| Kuznetsov, ML | 1 |
| Karmakar, A | 1 |
| Guedes da Silva, MFC | 1 |
| Koch, B | 1 |
| Pombeiro, AJL | 1 |
| Liao, T | 1 |
| Liu, C | 1 |
| Ren, J | 1 |
| Chen, H | 1 |
| Kuang, Y | 1 |
| Jiang, B | 1 |
| Chen, J | 1 |
| Sun, Z | 1 |
| Li, C | 1 |
| Zhang, J | 1 |
| Yao, D | 1 |
| Jiang, Y | 2 |
| Huang, J | 1 |
| Yang, S | 1 |
| Wang, J | 1 |
| Wińska, P | 1 |
| Skierka, K | 1 |
| Łukowska-Chojnacka, E | 1 |
| Koronkiewicz, M | 1 |
| Cieśla, J | 1 |
| Bretner, M | 1 |
| Mostafa, AS | 1 |
| Gomaa, RM | 1 |
| Elmorsy, MA | 1 |
| Dhanwal, V | 1 |
| Katoch, A | 1 |
| Singh, A | 1 |
| Chakraborty, S | 1 |
| Faheem, MM | 1 |
| Kaur, G | 1 |
| Nayak, D | 1 |
| Singh, N | 1 |
| Goswami, A | 1 |
| Kaur, N | 1 |
| Madhu, S | 1 |
| Sharma, DK | 1 |
| Basu, SK | 1 |
| Jadhav, S | 1 |
| Chowdhury, A | 1 |
| Ravikanth, M | 1 |
| Chu, B | 1 |
| Liu, F | 1 |
| Li, L | 1 |
| Ding, C | 1 |
| Chen, K | 1 |
| Sun, Q | 1 |
| Shen, Z | 1 |
| Tan, Y | 1 |
| Tan, C | 1 |
| Liang, Y | 1 |
| Zhou, Y | 1 |
| Deng, S | 1 |
| Chen, T | 1 |
| Nayak, VL | 1 |
| Nagesh, N | 1 |
| Ravikumar, A | 1 |
| Bagul, C | 1 |
| Vishnuvardhan, MVPS | 1 |
| Srinivasulu, V | 1 |
| Kamal, A | 1 |
| Taher, AT | 1 |
| Khalil, NA | 1 |
| Ahmed, EM | 1 |
| Ragab, YM | 1 |
| Abdul Rahim, AS | 1 |
| Salhimi, SM | 1 |
| Arumugam, N | 1 |
| Pin, LC | 1 |
| Yee, NS | 1 |
| Muttiah, NN | 1 |
| Keat, WB | 1 |
| Abd Hamid, S | 1 |
| Osman, H | 1 |
| Mat, Ib | 1 |
| Gümüş, F | 1 |
| Algül, O | 1 |
| Eren, G | 1 |
| Eroğlu, H | 1 |
| Diril, N | 1 |
| Gür, S | 1 |
| Ozkul, A | 1 |
14 other studies available for benzimidazole and Breast Cancer
| Article | Year |
|---|---|
Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti- Breast Cancer (MDA-MB-231, MCF-7) Agents.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell | 2021 |
Influence of anchoring moieties on new benzimidazole-based Schiff base copper(II) complexes towards estrogen dependent breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Cattle; Cell Cycle Chec | 2021 |
A chitosan/mesoporous silica nanoparticle-based anticancer drug delivery system with a "tumor-triggered targeting" property.
Topics: Adamantane; Animals; Antibiotics, Antineoplastic; Benzimidazoles; beta-Cyclodextrins; Breast Neoplas | 2021 |
Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells.
Topics: Antineoplastic Agents; Autophagy; Benzimidazoles; Breast Neoplasms; Cell Survival; Dose-Response Rel | 2017 |
Effect of Simultaneous Inhibition of Protein Kinase CK2 and Thymidylate Synthase in Leukemia and Breast Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Casein Kinase II; Cell Line, Tum | 2018 |
Design and synthesis of 2-phenyl benzimidazole derivatives as VEGFR-2 inhibitors with anti-breast cancer activity.
Topics: Benzimidazoles; Binding Sites; Breast Neoplasms; Cell Line; Cell Survival; Doxorubicin; Drug Design; | 2019 |
Self-assembled organic nanoparticles of benzimidazole analogue exhibit enhanced uptake in 3D tumor spheroids and oxidative stress induced cytotoxicity in breast cancer.
Topics: Apoptosis; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; M | 2019 |
Sensing Hg(II) in vitro and in vivo using a benzimidazole substituted BODIPY.
Topics: Benzimidazoles; Boron Compounds; Breast Neoplasms; Cell Line, Tumor; Female; Fluorescent Dyes; Human | 2013 |
A benzimidazole derivative exhibiting antitumor activity blocks EGFR and HER2 activity and upregulates DR5 in breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Cell Proliferation; Erb | 2015 |
Microwave-Assisted Syntheses of Benzimidazole-Containing Selenadiazole Derivatives That Induce Cell-Cycle Arrest and Apoptosis in Human Breast Cancer Cells by Activation of the ROS/AKT Pathway.
Topics: Antineoplastic Agents; Apoptosis; Azoles; Benzimidazoles; Breast Neoplasms; Cell Cycle Checkpoints; | 2016 |
2-aryl benzimidazole conjugate induced apoptosis in human breast cancer MCF-7 cells through caspase independent pathway.
Topics: Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Benzimidazoles; Breast Neoplasms; | 2017 |
Synthesis of certain 2-substituted-1H-benzimidazole derivatives as antimicrobial and cytotoxic agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; C | 2012 |
Microwave-assisted synthesis of sec/tert-butyl 2-arylbenzimidazoles and their unexpected antiproliferative activity towards ER negative breast cancer cells.
Topics: Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose- | 2013 |
Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum(II) complexes with 2-substituted benzimidazole ligands.
Topics: Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cisplatin; Dose-Response Relationship, Drug | 2003 |