benzene has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 25 studies
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL) have not been systematically assessed." | 8.90 | Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies. ( Bai, Y; Bi, Y; Li, Z; Wang, H; Zhang, S; Zhou, Y; Zhu, J, 2014) |
| "A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous." | 8.86 | Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010) |
| "Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia." | 7.78 | Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012) |
| "The meta-SMR for acute myeloid leukemia was 0." | 6.39 | Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996) |
| " However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL) have not been systematically assessed." | 4.90 | Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies. ( Bai, Y; Bi, Y; Li, Z; Wang, H; Zhang, S; Zhou, Y; Zhu, J, 2014) |
| "A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous." | 4.86 | Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010) |
| "We aimed to evaluate the impact of the EPA's Mobile Source Air Toxics rules (MSAT), which targeted benzene emissions, on childhood and young adult leukemia and lymphoma incidence in Alaska." | 4.31 | Mobile Source Benzene Regulations and Risk of Childhood and Young Adult Hematologic Cancers in Alaska: A Quasi-experimental Study. ( Frazier, AL; Laden, F; Nethery, RC; Vega, S, 2023) |
| "Petrol stations emit benzene and other contaminants that have been associated with an increased risk of childhood leukemia." | 4.31 | Residential proximity to petrol stations and risk of childhood leukemia. ( Bellelli, A; Cellini, M; Costanzini, S; Filippini, T; Malagoli, C; Malavolti, M; Palazzi, G; Teggi, S; Vinceti, M; Wise, LA, 2023) |
| "In a case-cohort study with follow-up of 110 631 Chinese workers during 1972-1999, we evaluated benzene exposure-response for non-Hodgkin lymphoma (NHL), lymphoid leukemias (LL), acute lymphocytic leukemia (ALL), and total lymphoid neoplasms (LN)." | 3.96 | Benzene exposure-response and risk of lymphoid neoplasms in Chinese workers: A multicenter case-cohort study. ( Dores, GM; Gilbert, ES; Hayes, RB; Ji, BT; Lan, Q; Li, GL; Linet, MS; Portengen, L; Rothman, N; Vermeulen, R; Yin, SN, 2020) |
| "Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia." | 3.78 | Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012) |
| "Benzene is an established cause of leukemia in adults, especially acute non-lymphocytic leukemia (ANLL)." | 3.69 | Environmental exposure to gasoline and leukemia in children and young adults--an ecology study. ( Järvholm, B; Nordlinder, R, 1997) |
| "Benzene is an established cause of adult leukemia, but whether it is associated with childhood leukemia remains unclear." | 2.53 | Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis. ( Carlos-Wallace, FM; Rader, G; Smith, MT; Steinmaus, C; Zhang, L, 2016) |
| "Discussion and synthesis of the animal cancer studies and mechanistic data related to specific cancers also were limited." | 2.47 | The IARC october 2009 evaluation of benzene carcinogenicity was incomplete and needs to be reconsidered. ( Infante, PF, 2011) |
| "The meta-SMR for acute myeloid leukemia was 0." | 2.39 | Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996) |
| "Benzene was largely banned from Danish workplaces after 1975, thus this case-control study focused on the immediately prior years." | 1.51 | Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study. ( Contreras, ZA; Hansen, J; He, D; Heck, JE; Olsen, J; Ritz, B, 2019) |
| "Benzene exposure was assessed through self-reported exposure to "gasoline or exhaust"." | 1.48 | Maternal exposure to gasoline and exhaust increases the risk of childhood leukaemia in offspring - a prospective study in the Norwegian Mother and Child Cohort Study. ( Baccarelli, A; Bjørge, T; Bråtveit, M; Christiani, DC; Gjertsen, BT; Hollund, BE; Kirkeleit, J; Mattioli, S; Riise, T, 2018) |
| "Etoposide was used as a positive control as it is a topo II poison and established human leukemogen that has previously been shown to induce END in Chinese hamster ovary cells." | 1.35 | The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells. ( Guo, W; Ji, Z; McHale, CM; Smith, MT; Zhang, L, 2009) |
| "This study investigated benzene-induced neoplasia in CBA/Ca mice, with special emphasis on hematopoietic tissues." | 1.29 | Carcinogenicity of inhaled benzene in CBA mice. ( Everitt, JI; Farris, GM; Irons, RD; Popp, JA, 1993) |
| "All cancers, acute lymphocytic leukemia (ALL), and brain cancer were examined in relation to parental occupation during the year prior to the birth of the child." | 1.28 | Use of a job-exposure matrix to evaluate parental occupation and childhood cancer. ( Feingold, L; John, EM; Savitz, DA, 1992) |
| "A case of early B t(4;11)(q21;q23) acute lymphoblastic leukemia (ALL) with low white blood cell (WBC) count, without splenomegaly, short survival time, in a patient previously exposed to benzol is presented." | 1.28 | Acute lymphoblastic leukemia with t(4;11) in a patient previously exposed to a carcinogen. ( Caballín, MR; Coll, MD; Egozcue, J; Solé, F; Woessner, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 12 (48.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nethery, RC | 1 |
| Vega, S | 1 |
| Frazier, AL | 1 |
| Laden, F | 1 |
| Malavolti, M | 1 |
| Malagoli, C | 2 |
| Filippini, T | 1 |
| Wise, LA | 1 |
| Bellelli, A | 1 |
| Palazzi, G | 2 |
| Cellini, M | 1 |
| Costanzini, S | 1 |
| Teggi, S | 2 |
| Vinceti, M | 2 |
| Linet, MS | 1 |
| Gilbert, ES | 1 |
| Vermeulen, R | 1 |
| Dores, GM | 1 |
| Yin, SN | 1 |
| Portengen, L | 1 |
| Hayes, RB | 1 |
| Ji, BT | 1 |
| Lan, Q | 1 |
| Li, GL | 1 |
| Rothman, N | 1 |
| Janitz, AE | 1 |
| Campbell, JE | 1 |
| Magzamen, S | 1 |
| Pate, A | 1 |
| Stoner, JA | 1 |
| Peck, JD | 1 |
| Raaschou-Nielsen, O | 1 |
| Hvidtfeldt, UA | 1 |
| Roswall, N | 1 |
| Hertel, O | 1 |
| Poulsen, AH | 1 |
| Sørensen, M | 1 |
| Kirkeleit, J | 1 |
| Riise, T | 1 |
| Bjørge, T | 1 |
| Christiani, DC | 1 |
| Bråtveit, M | 1 |
| Baccarelli, A | 1 |
| Mattioli, S | 1 |
| Hollund, BE | 1 |
| Gjertsen, BT | 1 |
| Heck, JE | 1 |
| He, D | 1 |
| Contreras, ZA | 1 |
| Ritz, B | 1 |
| Olsen, J | 1 |
| Hansen, J | 1 |
| Zhou, Y | 1 |
| Zhang, S | 1 |
| Li, Z | 1 |
| Zhu, J | 1 |
| Bi, Y | 1 |
| Bai, Y | 1 |
| Wang, H | 1 |
| Houot, J | 1 |
| Marquant, F | 1 |
| Goujon, S | 1 |
| Faure, L | 1 |
| Honoré, C | 1 |
| Roth, MH | 1 |
| Hémon, D | 2 |
| Clavel, J | 2 |
| Carlos-Wallace, FM | 1 |
| Zhang, L | 2 |
| Smith, MT | 3 |
| Rader, G | 1 |
| Steinmaus, C | 1 |
| Symanski, E | 1 |
| Tee Lewis, PG | 1 |
| Chen, TY | 1 |
| Chan, W | 1 |
| Lai, D | 1 |
| Ma, X | 1 |
| Ji, Z | 1 |
| Guo, W | 1 |
| McHale, CM | 1 |
| Khalade, A | 1 |
| Jaakkola, MS | 1 |
| Pukkala, E | 1 |
| Jaakkola, JJ | 1 |
| Cogliano, VJ | 1 |
| Baan, R | 1 |
| Straif, K | 1 |
| Infante, PF | 1 |
| Rothman, KJ | 1 |
| Crespi, CM | 1 |
| Sterni, A | 1 |
| Cherubini, A | 1 |
| Guerra, L | 1 |
| Maffeis, G | 1 |
| Ferretti, E | 1 |
| Fabbi, S | 1 |
| Consonni, D | 1 |
| De Girolamo, G | 1 |
| Meggiato, A | 1 |
| Paolucci, P | 1 |
| Skibola, CF | 1 |
| Allan, JM | 1 |
| Morgan, GJ | 1 |
| Steffen, C | 1 |
| Auclerc, MF | 1 |
| Auvrignon, A | 1 |
| Baruchel, A | 1 |
| Kebaili, K | 1 |
| Lambilliotte, A | 1 |
| Leverger, G | 1 |
| Sommelet, D | 1 |
| Vilmer, E | 1 |
| Infante-Rivard, C | 1 |
| Vermunt, JK | 1 |
| Weinberg, CR | 1 |
| Farris, GM | 1 |
| Everitt, JI | 1 |
| Irons, RD | 1 |
| Popp, JA | 1 |
| Raabe, GK | 1 |
| Wong, O | 1 |
| Rushton, L | 1 |
| Romaniuk, H | 1 |
| Nordlinder, R | 1 |
| Järvholm, B | 1 |
| Feingold, L | 1 |
| Savitz, DA | 1 |
| John, EM | 1 |
| Solé, F | 1 |
| Caballín, MR | 1 |
| Coll, MD | 1 |
| Woessner, S | 1 |
| Egozcue, J | 1 |
7 reviews available for benzene and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies.
Topics: Benzene; Case-Control Studies; Cohort Studies; Female; Humans; Maternal Exposure; Odds Ratio; Precur | 2014 |
Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis.
Topics: Adolescent; Benzene; Child; Child, Preschool; Environmental Exposure; Female; Humans; Infant; Infant | 2016 |
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis.
Topics: Benzene; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, B | 2010 |
Updating IARC's carcinogenicity assessment of benzene.
Topics: Benzene; Carcinogens, Environmental; Congresses as Topic; Humans; International Agencies; Internatio | 2011 |
The IARC october 2009 evaluation of benzene carcinogenicity was incomplete and needs to be reconsidered.
Topics: Benzene; Carcinogens, Environmental; Congresses as Topic; Humans; International Agencies; Internatio | 2011 |
Causal models of leukaemia and lymphoma.
Topics: Autoimmunity; Benzene; Biomarkers; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Models, Bio | 2004 |
Leukemia mortality by cell type in petroleum workers with potential exposure to benzene.
Topics: Benzene; Cohort Studies; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloge | 1996 |
1 trial available for benzene and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Ambient benzene at the residence and risk for subtypes of childhood leukemia, lymphoma and CNS tumor.
Topics: Adolescent; Adult; Air Pollutants; Benzene; Case-Control Studies; Central Nervous System Neoplasms; | 2018 |
17 other studies available for benzene and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Mobile Source Benzene Regulations and Risk of Childhood and Young Adult Hematologic Cancers in Alaska: A Quasi-experimental Study.
Topics: Air Pollutants; Alaska; Benzene; Child; Hematologic Neoplasms; Humans; Lymphoma; Precursor Cell Lymp | 2023 |
Residential proximity to petrol stations and risk of childhood leukemia.
Topics: Adolescent; Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Gasoline; Humans | 2023 |
Benzene exposure-response and risk of lymphoid neoplasms in Chinese workers: A multicenter case-cohort study.
Topics: Adolescent; Adult; Benzene; China; Cohort Studies; Female; Follow-Up Studies; Humans; Leukemia, Lymp | 2020 |
Benzene and childhood acute leukemia in Oklahoma.
Topics: Adolescent; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Environm | 2017 |
Maternal exposure to gasoline and exhaust increases the risk of childhood leukaemia in offspring - a prospective study in the Norwegian Mother and Child Cohort Study.
Topics: Benzene; Female; Gasoline; Humans; Male; Maternal Exposure; Norway; Precursor Cell Lymphoblastic Leu | 2018 |
Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study.
Topics: Adolescent; Adult; Benzene; Case-Control Studies; Child; Child, Preschool; Denmark; Female; Humans; | 2019 |
Residential Proximity to Heavy-Traffic Roads, Benzene Exposure, and Childhood Leukemia-The GEOCAP Study, 2002-2007.
Topics: Adolescent; Air Pollution; Benzene; Carcinogens; Case-Control Studies; Child; Child, Preschool; Fema | 2015 |
Air toxics and early childhood acute lymphocytic leukemia in Texas, a population based case control study.
Topics: Adult; Air Pollutants; Benzene; Butadienes; Case-Control Studies; Child, Preschool; Environmental Mo | 2016 |
The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells.
Topics: Benzene; Cell Line, Tumor; Chromosomes; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gen | 2009 |
Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population.
Topics: Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Fema | 2012 |
Acute childhood leukaemia and environmental exposure to potential sources of benzene and other hydrocarbons; a case-control study.
Topics: Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Female; France; Huma | 2004 |
Excess transmission of the NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia.
Topics: Adolescent; Benzene; Child; Child, Preschool; Family Health; Female; Humans; Infant; Infant, Newborn | 2007 |
Carcinogenicity of inhaled benzene in CBA mice.
Topics: Administration, Inhalation; Animals; Benzene; Blood Cell Count; Bone Marrow; Carcinogenicity Tests; | 1993 |
A case-control study to investigate the risk of leukaemia associated with exposure to benzene in petroleum marketing and distribution workers in the United Kingdom.
Topics: Benzene; Case-Control Studies; Cohort Studies; Death Certificates; Humans; Leukemia; Leukemia, Lymph | 1997 |
Environmental exposure to gasoline and leukemia in children and young adults--an ecology study.
Topics: Adolescent; Adult; Automobiles; Benzene; Child; Child, Preschool; Environmental Exposure; Female; Ga | 1997 |
Use of a job-exposure matrix to evaluate parental occupation and childhood cancer.
Topics: Adolescent; Benzene; Beryllium; Brain Neoplasms; Carcinogens; Child; Child, Preschool; Creosote; Fem | 1992 |
Acute lymphoblastic leukemia with t(4;11) in a patient previously exposed to a carcinogen.
Topics: Benzene; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Female; Genetic Markers; Humans; K | 1990 |