benzene has been researched along with Leukemia in 382 studies
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzene causes acute myeloid leukemia and probably other hematological malignancies." | 8.88 | Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment. ( McHale, CM; Smith, MT; Zhang, L, 2012) |
| "Chronic exposure to high concentrations of benzene is an established cause of acute myeloid leukemia (AML) in occupationally exposed workers." | 8.86 | A review of the potential association between childhood leukemia and benzene. ( Hays, S; Pyatt, D, 2010) |
| "A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous." | 8.86 | Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010) |
| "The epidemiologic literature on benzene exposure and leukemia in the MEDLINE and TOXNET databases was examined through October 2004 using the keywords "benzene", "leukemia" and "adverse health effects"." | 8.82 | Review of the literature on benzene exposure and leukemia subtypes. ( Rosamilia, K; Schnatter, AR; Wojcik, NC, 2005) |
| "An overall hypothesis for benzene-induced leukemia is proposed." | 8.79 | The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia. ( Smith, MT, 1996) |
| " Supreme Court decision on the Occupational Safety and Health Administration's (OSHA) proposal to lower the occupational benzene standard from 10 ppm to 1 ppm, numerous quantitative assessments of the leukemia risk of benzene exposure have been prepared." | 8.77 | Review and update of leukemia risk potentially associated with occupational exposure to benzene. ( Brett, SM; Chinchilli, VM; Rodricks, JV, 1989) |
| "In 1982, White et al published an assessment of quantitative leukemia risk associated with lifetime occupational exposure to benzene." | 8.77 | Projections of leukemia risk associated with occupational exposure to benzene. ( Infante, PF; White, MC, 1985) |
| "Genome-wide sequencing may extensively identify potential pathogenic variants, which helps to understand mechanisms of tumorigenesis, but such study has not been reported in benzene-induced leukemia (BIL)." | 8.31 | Whole-exome sequencing identified recurrent and novel variants in benzene-induced leukemia. ( Deng, L; Li, P; Lin, D; Wang, D; Zhang, M; Zhang, N; Zhang, Y; Zhang, Z, 2023) |
| "In this study, the annual leukemia mortality rate is estimated by occupational groups potentially exposed to benzene in Brazil and compared to non-exposed workers by sex." | 8.31 | Leukemia Mortality among Benzene-Exposed Workers in Brazil (2006-2011). ( Moura-Corrêa, MJ, 2023) |
| "This study analyzed the contribution of the Clinica del Lavoro in Milan, Italy, to studies of the relationship between exposure to benzene and leukemia." | 7.91 | Benzene and leukemia: from scientific evidence to regulations. A historical example. ( Belingheri, M; De Vito, G; Fustinoni, S; Porro, A; Riva, MA, 2019) |
| "The study relies on the development of a methodology for assessing the determinants that comprise the overall leukemia risk due to benzene exposure and how these are affected by outdoor and indoor air quality regulation." | 7.79 | A methodological frame for assessing benzene induced leukemia risk mitigation due to policy measures. ( Gotti, A; Karakitsios, SP; Kassomenos, PA; Pilidis, GA; Sarigiannis, DΑ, 2013) |
| "Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia." | 7.78 | Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012) |
| "Evidence suggests that de novo, therapy-related and benzene-induced acute myeloid leukemias (AML) occur via similar cytogenetic and genetic pathways, several of which involve aneuploidy, the loss or gain of chromosomes." | 7.77 | Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene. ( Guo, W; Hubbard, AE; Ji, Z; Lan, Q; Li, G; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2011) |
| " The approach is demonstrated with 2 studies of leukemia in benzene-exposed workers, one conducted in the Australian petroleum industry (1981-1999) and one conducted in a US rubber hydrochloride production factory in Ohio (1940-1996)." | 7.77 | The impact of saturable metabolism on exposure-response relations in 2 studies of benzene-induced leukemia. ( Glass, DC; Kromhout, H; Portengen, L; Rappaport, SM; Vermeulen, R; Vlaanderen, J, 2011) |
| "Benzene is a well-known environmental pollutant that can induce hematotoxicity, aplastic anemia, acute myelogenous leukemia, and lymphoma." | 7.77 | Differential gene expression profiles of human leukemia cell lines exposed to benzene and its metabolites. ( Kim, YJ; Ryu, JC; Sarma, SN, 2011) |
| " The results of several independent epidemiologic studies of occupational cohorts with benzene exposure and the development of leukemia will be presented in order to find common aspects." | 7.76 | Implications of latency period between benzene exposure and development of leukemia--a synopsis of literature. ( Triebig, G, 2010) |
| "Previous evaluations of the shape of the benzene-leukemia exposure-response curve (ERC) were based on a single set or on small sets of human occupational studies." | 7.76 | Flexible meta-regression to assess the shape of the benzene-leukemia exposure-response curve. ( Kromhout, H; Lan, Q; Portengen, L; Rothman, N; Vermeulen, R; Vlaanderen, J, 2010) |
| " As a basis for additionally coordinating and focusing research on critical data gaps in a risk assessment context, five key events in the mode of action for benzene-induced leukemia are proposed: (1) benzene metabolism via Cytochrome P450, (2) the interaction of benzene metabolites with target cells in the bone marrow, (3) formation of initiated, mutated target cells, (4) selective proliferation of the mutated cells and (5) production of leukemia." | 7.76 | Proposed mode of action of benzene-induced leukemia: Interpreting available data and identifying critical data gaps for risk assessment. ( Klaunig, JE; Meek, ME, 2010) |
| " Data on leukemia mortality and occupational exposure to benzene among rubber hydrochloride production workers in Ohio (1940-1996) were analyzed by using this approach." | 7.75 | Multistage modeling of leukemia in benzene workers: a simple approach to fitting the 2-stage clonal expansion model. ( Richardson, DB, 2009) |
| "Epidemiological studies show that benzene exposure is associated with an increased incidence of leukemia and perhaps lymphoma." | 7.74 | Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Li, G; Lu, W; Rothman, N; Smith, MT; Yang, W; Yin, S; Zhang, L, 2007) |
| "I evaluated variation in benzene-related leukemia with age at exposure and time since exposure." | 7.74 | Temporal variation in the association between benzene and leukemia mortality. ( Richardson, DB, 2008) |
| "To investigate the leukemia risk in a group of benzene exposed workers." | 7.73 | Leukemia risk in caprolactam workers exposed to benzene. ( de Cock, J; Drooge, H; Scheffers, T; Slangen, J; Swaen, GM, 2005) |
| "The study attempted to add years of follow-up to an earlier study describing excess leukemia among workers exposed to benzene-based glues in a shoe-factory and to conduct a quantitative exposure assessment of the exposure to benzene and the risk of leukemia." | 7.72 | Exposure to benzene and risk of leukemia among shoe factory workers. ( Consonni, D; Quinn, M; Seniori Costantini, A; Zappa, M, 2003) |
| "We found an excess risk of leukemia associated with cumulative benzene exposures and benzene exposure intensities that were considerably lower than reported in previous studies." | 7.72 | Leukemia risk associated with low-level benzene exposure. ( Adams, GG; Bisby, JA; Fritschi, L; Gibbons, C; Glass, DC; Gray, CN; Jolley, DJ; Manuell, R; Sim, MR, 2003) |
| "In 1974, Professor Muzaffer Aksoy established a link to leukemia in humans as a result of occupational exposure to benzene." | 7.72 | Story of benzene and leukemia: epidemiologic approach of Muzaffer Aksoy. ( Akbulut, T; Dikici, M; Sabuncu, H; Yaris, E; Yaris, F, 2004) |
| "Many occupational and environmental exposures have been implicated in the etiology of leukemia, but only a few, such as benzene, are well-established leukemogens." | 7.71 | Leukemia in relation to occupational exposures to benzene and other agents: a case-control study nested in a cohort of gas and electric utility workers. ( Chevalier, A; Crinquand-Calastreng, A; Goldberg, M; Guénel, P; Imbernon, E, 2002) |
| "To study the relationship between glutathione S transferase M1(GST mu) gene deletion and leukemia in workers exposed to benzene." | 7.71 | [Study on the relationship between glutathione S transferase mu gene deletion and leukemia in workers exposed to benzene]. ( Li, C; Long, Y; Wang, W; Xiang, C; Zhan, C, 2002) |
| "Cigarette smoking is associated with an increased risk of leukemia; benzene, an established leukemogen, is present in cigarette smoke." | 7.70 | The contribution of benzene to smoking-induced leukemia. ( Ball, LM; Duell, EJ; Hertz-Picciotto, I; Korte, JE; Schulz, MR, 2000) |
| "A matched case-control study of leukemia risk in relation to the temporal pattern of benzene exposures was performed using data from the National Institute of Occupational Safety and Health." | 7.70 | Leukemia after exposure to benzene: temporal trends and implications for standards. ( Finkelstein, MM, 2000) |
| "Gender differences in risk for leukemia and other selected and combined disease categories were examined by major occupational category for 74,828 benzene-exposed workers compared to 35,805 unexposed workers from 12 cities in China." | 7.69 | Gender differences in hematopoietic and lymphoproliferative disorders and other cancer risks by major occupational group among workers exposed to benzene in China. ( Chow, WH; Dosemeci, M; Hayes, RB; Jiang, ZL; Li, GL; Linet, MS; Wacholder, S; Wang, YZ; Yin, SN; Zhang, WU, 1994) |
| "The detailed work histories of the individual workers composing the Pliofilm cohort represent a unique resource for estimating the dose-response for leukemia that may follow occupational exposure to benzene." | 7.69 | Leukemia risk associated with benzene exposure in the pliofilm cohort. II. Risk estimates. ( Brett, SM; Chinchilli, VM; Paxton, MB; Rodricks, JV, 1994) |
| "This report updates the risk assessment by Crump and Allen (1984) for benzene-induced leukemia that was used by OSHA (1987) to support its reduction of the permissible exposure limit (PEL) to 1 ppm and that also was the basis for EPA's (1985) interim "unit risk" for benzene." | 7.69 | Risk of benzene-induced leukemia: a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates. ( Crump, KS, 1994) |
| "Retrospective, quantitative estimates of exposure to 1,3-butadiene, styrene and benzene were developed for a follow-up study of leukemia mortality among 16610 subjects employed at six North American styrene-butadiene rubber manufacturing plants (418846 person-years, 58 leukemia deaths)." | 7.69 | Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry. ( Cole, P; Delzell, E; Hovinga, M; Julian, J; Larson, R; Macaluso, M; Muir, D; Sathiakumar, N, 1996) |
| "This study was conducted to evaluate the relationship between leukemia occurrence and long-term, low-level benzene exposures in petroleum distribution workers." | 7.69 | The relationship between low-level benzene exposure and leukemia in Canadian petroleum distribution workers. ( Armstrong, TW; Huebner, WW; Katz, AM; Nicolich, MJ; Pearlman, ED; Schnatter, AR; Thompson, LS, 1996) |
| "This report updates the risk assessment by Crump and Allen for benzene-induced leukemia that was based on a cohort exposed to benzene in the manufacture of Pliofilm." | 7.69 | Risk of benzene-induced leukemia predicted from the Pliofilm cohort. ( Crump, KS, 1996) |
| "To assess quantitatively the association between benzene and leukemia, we evaluated the rate of mortality experienced by a cohort occupationally exposed to benzene." | 7.67 | Benzene and leukemia: an epidemiologic risk assessment. ( Rinsky, RA, 1989) |
| "To assess quantitatively the association between benzene exposure and leukemia, we examined the mortality rate of a cohort with occupational exposure to benzene." | 7.67 | Benzene and leukemia. An epidemiologic risk assessment. ( Filloon, TG; Hornung, R; Landrigan, PJ; Okun, AH; Rinsky, RA; Smith, AB; Young, RJ, 1987) |
| "Benzene has the sad privilege of being the only industrial chemical inducing leukemia in susceptible individuals chronically exposed to its vapors." | 7.66 | An hypothesis for the induction of leukemia by benzene. ( Braier, L, 1983) |
| "To evaluate the possible association between occupational exposure to benzene and subsequent death from leukemia, the National Institute for Occupational Safety and Health (NIOSH) conducted a retrospective cohort mortality study of workers who had been exposed to benzene in the manufacture of rubber hydrochloride at two locations in Ohio." | 7.66 | Leukemia in benzene workers. ( Rinsky, RA; Smith, AB; Young, RJ, 1981) |
| "The distribution of various types of leukemia due to chronic exposure to benzene is described in a series comprising 34 cases." | 7.65 | Types of leukemia in chronic benzene poisoning. A study in thirty-four patients. ( Aksoy, M; Dinçol, G; Erdem, S, 1976) |
| "Benzene is an occupational and environmental toxicant, causing hematopoietic damage." | 6.82 | Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis. ( Cong, X; Pu, Y; Sun, Q; Wang, B; Xu, S; Zhang, J, 2022) |
| "Benzene is an environmental toxicant found in many consumer products." | 6.66 | Benzene and its effects on cell signaling pathways related to hematopoiesis and leukemia. ( Lu, PCW; Shahbaz, S; Winn, LM, 2020) |
| "The meta-SMR for acute myeloid leukemia was 0." | 6.39 | Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996) |
| " The dose-response relationship is strongly nonlinear." | 6.38 | Consistencies and inconsistencies underlying the quantitative assessment of leukemia risk from benzene exposure. ( Byrd, DM; Grunwald, H; Lamm, SH; Walters, AS; Wilson, R, 1989) |
| "Leukemia was induced by intravenous injection of 0." | 5.40 | Chemopreventive and anti-leukemic effects of ethanol extracts of Moringa oleifera leaves on wistar rats bearing benzene induced leukemia. ( Adedeji, AL; Adedosu, OT; Akanni, EO; Olaniran, OI; Oloke, JK, 2014) |
| "Leukemia is the most common cancer in children." | 5.30 | Biomarkers of leukemia risk: benzene as a model. ( Smith, MT; Zhang, L, 1998) |
| "The fact that leukemia has not been observed in any individual who started employment in Pliofilm production after 1950 suggests that the observed leukemia cases could be a response to very high levels of benzene exposure that occurred during the early years of this manufacturing process." | 5.29 | Leukemia risk associated with benzene exposure in the pliofilm cohort: I. Mortality update and exposure distribution. ( Brett, SM; Chinchilli, VM; Paxton, MB; Rodricks, JV, 1994) |
| " Neither the Paustenbach nor the Crump exposures gave dose-response estimates as steep as that resulting from the Rinsky exposures." | 5.29 | Leukemia risk associated with benzene exposure in the Pliofilm cohort. ( Paxton, MB, 1996) |
| "For certain cancers, increased mortality was noted among benzene-exposed males in comparison with that among unexposed males; the standardized mortality ratios (SMR) were elevated for leukemia (SMR = 5." | 5.28 | A retrospective cohort study of leukemia and other cancers in benzene workers. ( Chen, YJ; Fu, ZI; Jin, C; Li, GL; Luo, SJ; Tain, FD; Wang, GC; Ye, PZ; Yin, SN; Zhang, JZ, 1989) |
| "Benzene is a well documented carcinogen for the hematic and lymphopoietic system, and experimental research confirms its carcinogenicity for tumors of other sites." | 5.28 | Aplastic anemia, leukemia and other cancer mortality in a cohort of shoe workers exposed to benzene. ( Buiatti, E; Kaldor, JM; Miligi, L; Paci, E; Petrioli, G; Pucci, N; Scarpelli, A; Seniori Costantini, AS; Simonato, L; Winkelmann, R, 1989) |
| "Benzene has been known to be a bone marrow poison for almost a century." | 5.27 | Benzene: epidemiologic observations of leukemia by cell type and adverse health effects associated with low-level exposure. ( Infante, PF; White, MC, 1983) |
| " Given a similar degree of exposure, why do some workers remain apparently unaffected, while others develop alterations of the hemopoietic system? It is hypothesized that inadequate nutritional status of possibly several nutrients including iron, selenium, methionine and ascorbic acid may enhance susceptibility to adverse effects caused by benzene." | 5.26 | Does nutritional status affect benzene induced toxicity and/or leukemia? ( Calabrese, EJ, 1980) |
| "Benzene is a known carcinogen for adult leukemia." | 5.22 | Childhood cancer and residential proximity to petrol stations: a nationwide registry-based case-control study in Switzerland and an updated meta-analysis. ( Ammann, RA; Diezi, M; Konstantinoudis, G; Kreis, C; Kühni, C; Mazzei, A; Spycher, BD; Zwahlen, M, 2022) |
| "Exposure to chemicals produced by petrochemical industrial complexes (PICs), such as benzene, ionizing radiation, and particulate matters, may contribute to the development of leukemia." | 5.05 | Residential exposure to petrochemical industrial complexes and the risk of leukemia: A systematic review and exposure-response meta-analysis. ( Brown, KD; Chen, ST; Hsu, YT; Lin, CK; Pokharel, B; Wei, Y, 2020) |
| "Electronic databases were searched for studies correlated pediatric leukemia with (1) ionizing radiation; (2) benzene; (3) parental drug use (4) parental alcohol use; (5) genetic factors." | 4.93 | A review of risk factors for childhood leukemia. ( An, Q; Jin, MW; Wang, P; Xu, SM, 2016) |
| "Benzene causes acute myeloid leukemia and probably other hematological malignancies." | 4.88 | Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment. ( McHale, CM; Smith, MT; Zhang, L, 2012) |
| "Chronic exposure to high concentrations of benzene is an established cause of acute myeloid leukemia (AML) in occupationally exposed workers." | 4.86 | A review of the potential association between childhood leukemia and benzene. ( Hays, S; Pyatt, D, 2010) |
| "A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous." | 4.86 | Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010) |
| "The epidemiologic literature on benzene exposure and leukemia in the MEDLINE and TOXNET databases was examined through October 2004 using the keywords "benzene", "leukemia" and "adverse health effects"." | 4.82 | Review of the literature on benzene exposure and leukemia subtypes. ( Rosamilia, K; Schnatter, AR; Wojcik, NC, 2005) |
| "Benzene is an established cause of human leukemia that is thought to act by producing chromosomal aberrations and altered in cell differentiation." | 4.81 | The nature of chromosomal aberrations detected in humans exposed to benzene. ( Eastmond, DA; Smith, MT; Zhang, L, 2002) |
| "This paper describes the epidemiological evidence on lung cancer and childhood leukemia in relation to traffic-related air pollution, with particular reference to diesel exhausts, polycyclic aromatic hydrocarbons (PAH) and benzene." | 4.80 | [Air pollution from traffic and the risk of tumors]. ( Forastiere, F; Lagorio, S; Lipsett, M; Menichini, E, 2000) |
| " Of particular interest is the relationship between exposure to benzene or benzene-containing liquids in the petroleum industry and leukemia risk." | 4.79 | Cell-type-specific leukemia analyses in a combined cohort of more than 208,000 petroleum workers in the United States and the United Kingdom, 1937-1989. ( Raabe, GK; Wong, O, 1995) |
| "Although the relationship between benzene and acute nonlymphocytic leukemia (ANLL) is well established, most of the analytic cohort investigations examining the relationship between benzene and hematologic neoplasms have evaluated only death certificates to validate diagnoses." | 4.79 | Hematopoietic malignancies and related disorders among benzene-exposed workers in China. ( Blot, W; Chow, WH; Dosemeci, M; Fraumeni, JF; Li, CY; Li, DG; Li, GL; Travis, LB; Yin, SN; Zhang, ZN, 1994) |
| "Although benzene is best known as a compound that causes bone marrow depression leading to aplastic anemia in animals and humans, it also induces acute myelogenous leukemia in humans." | 4.79 | A perspective on benzene leukemogenesis. ( Kalf, GF; Snyder, R, 1994) |
| "Exposure to benzene is generally accepted as a cause of acute myeloid leukemia (AML), but the association with other cell types of leukemia and other lymphatic and hematopoietic cancers is controversial." | 4.79 | Review of epidemiologic evidence on benzene and lymphatic and hematopoietic cancers. ( Andrews, KW; Savitz, DA, 1997) |
| "An overall hypothesis for benzene-induced leukemia is proposed." | 4.79 | The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia. ( Smith, MT, 1996) |
| " Over the last half-century a predominant paradigm has emerged to describe leukemia developing secondary to alkylating drug therapy or exposure to benzene in which progressive dysplastic changes, accompanied by a distinct pattern of clonal cytogenetic abnormalities, give rise to acute myelogenous leukemia." | 4.79 | The process of leukemogenesis. ( Irons, RD; Stillman, WS, 1996) |
| "Previous occupational cohort studies of benzene-exposed workers have for the most part used only death certificates to validate diagnoses of workers developing leukemia and other hematopoietic and lymphoproliferative malignancies and related disorders (HLD)." | 4.79 | Clinical features of hematopoietic malignancies and related disorders among benzene-exposed workers in China. Benzene Study Group. ( Blot, WJ; Chow, WH; Donaldson, J; Dosemeci, M; Hayes, RB; Li, CY; Li, DG; Li, GL; Linet, MS; Rothman, N; Travis, LB; Wacholder, S; Yin, SN; Zhang, ZN, 1996) |
| " A causal association between exposure to benzene and an increased risk of leukemia is well-established, as well as a suggested risk of lung and nasopharynx cancer in a Chinese cohort." | 4.79 | Organic solvents and cancer. ( Anttila, A; Hemminki, K; Lynge, E, 1997) |
| "Benzene, a common industrial chemical and a component of gasoline, is radiomimetic and exposure may lead progressively to aplastic anaemia, leukaemia, and multiple myeloma." | 4.78 | The toxicity of benzene and its metabolism and molecular pathology in human risk assessment. ( Anderson, D; Parke, DV; Yardley-Jones, A, 1991) |
| " Supreme Court decision on the Occupational Safety and Health Administration's (OSHA) proposal to lower the occupational benzene standard from 10 ppm to 1 ppm, numerous quantitative assessments of the leukemia risk of benzene exposure have been prepared." | 4.77 | Review and update of leukemia risk potentially associated with occupational exposure to benzene. ( Brett, SM; Chinchilli, VM; Rodricks, JV, 1989) |
| "In 1982, White et al published an assessment of quantitative leukemia risk associated with lifetime occupational exposure to benzene." | 4.77 | Projections of leukemia risk associated with occupational exposure to benzene. ( Infante, PF; White, MC, 1985) |
| " Using combined epidemiological and industrial hygiene data, a quantitative risk assessment of a lifetime exposure of workers to benzene and its association with leukemia is presented." | 4.76 | The application of epidemiology to the prevention of occupational cancer. ( Landrigan, PJ; Rinsky, RA, 1984) |
| "Production usage and potential occupational exposure to benzene are described in this review, as are selected, relevant reports presenting evidence evidence implicating benzene as a causative factor in leukemia, particularly acute myelogenous leukemia, pancytopenia (including aplastic anemia) and chromosomal aberrations." | 4.75 | Benzene--attempts to establish a lower exposure standard in the United States. A review. ( Zenz, C, 1978) |
| "Genome-wide sequencing may extensively identify potential pathogenic variants, which helps to understand mechanisms of tumorigenesis, but such study has not been reported in benzene-induced leukemia (BIL)." | 4.31 | Whole-exome sequencing identified recurrent and novel variants in benzene-induced leukemia. ( Deng, L; Li, P; Lin, D; Wang, D; Zhang, M; Zhang, N; Zhang, Y; Zhang, Z, 2023) |
| "Petrol stations emit benzene and other contaminants that have been associated with an increased risk of childhood leukemia." | 4.31 | Residential proximity to petrol stations and risk of childhood leukemia. ( Bellelli, A; Cellini, M; Costanzini, S; Filippini, T; Malagoli, C; Malavolti, M; Palazzi, G; Teggi, S; Vinceti, M; Wise, LA, 2023) |
| "Exposure to benzene results in peripheral blood cell reduction, aplastic anemia, and leukemia." | 4.31 | LncRNA OBFC2A modulated benzene metabolites-induced autophagy and apoptosis by interacting with LAMP2. ( Chen, Y; Gao, A; Guo, X; Ren, J; Wang, J; Zhang, W, 2023) |
| "In this study, the annual leukemia mortality rate is estimated by occupational groups potentially exposed to benzene in Brazil and compared to non-exposed workers by sex." | 4.31 | Leukemia Mortality among Benzene-Exposed Workers in Brazil (2006-2011). ( Moura-Corrêa, MJ, 2023) |
| " This study describes the efficacy of the combination of Cinnamomum zeylanicum and doxorubicin against benzene-induced leukemia." | 4.12 | Combined efficacy of Cinnamomum zeylanicum and doxorubicin against leukemia through regulation of TRAIL and NF-kappa B pathways in rat model. ( Ali, Z; Anees, M; Anis, RA; Bukhari, S; Essa, A; Fazal, F; Khan, I; Moran, L; Murtaza, I; Naeem, A; Siddique, MH; Sultan, A; Vanhara, P, 2022) |
| "As a hematopoietic carcinogen, benzene induces human leukemia through its active metabolites such as benzoquinone, which may cause oxidative damage to cancer-related nuclear genes by increasing reactive oxygen species (ROS)." | 4.02 | Genomic analysis of mutations in platelet mitochondria in a case of benzene-induced leukaemia: A case report. ( Cai, D; Li, P; Lin, D; Wang, D; Yang, X; Zhang, Y; Zhang, Z, 2021) |
| " Benzene (BZ) is a ubiquitous environmental pollutant and carcinogen that causes leukemia." | 4.02 | The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). ( Berthelet, J; Bui, LC; Chomienne, C; Dulphy, N; Dupret, JM; Guidez, F; Le Coadou, L; Michail, C; Rodrigues-Lima, F; Sirri, V; Wang, L, 2021) |
| "This study analyzed the contribution of the Clinica del Lavoro in Milan, Italy, to studies of the relationship between exposure to benzene and leukemia." | 3.91 | Benzene and leukemia: from scientific evidence to regulations. A historical example. ( Belingheri, M; De Vito, G; Fustinoni, S; Porro, A; Riva, MA, 2019) |
| "Although benzene has long been recognized as a cause of human leukemia, the mechanism by which this simple molecule causes cancer has been problematic." | 3.88 | Adductomic signatures of benzene exposure provide insights into cancer induction. ( Carlsson, H; Edmands, WMB; Grigoryan, H; Lan, Q; Li, GL; Rappaport, SM; Rothman, N; Smith, MT; Vermeulen, R; Yin, SN; Zhang, L, 2018) |
| "Benzene is an established cause of adult leukemia, but its role in childhood leukemia is less clear." | 3.85 | Steinmaus and Smith Respond to "Proximity to Gasoline Stations and Childhood Leukemia". ( Smith, MT; Steinmaus, C, 2017) |
| "High benzene exposure is related to acute nonlymphocytic leukemia." | 3.81 | Lymphatic and hematopoietic cancers among benzene-exposed workers. ( Anteau, SE; Bodnar, CM; Bodner, KM; Collins, JJ; Swaen, GM, 2015) |
| "Occupational and environmental exposure to chemicals such as benzene has been linked to increased risk of leukemia." | 3.81 | Non-radiation risk factors for leukemia: A case-control study among chornobyl cleanup workers in Ukraine. ( Babkina, N; Bazyka, D; Brenner, A; Chumak, V; Dyagil, I; Gudzenko, N; Hatch, M; Mabuchi, K; Reiss, RF; Zablotska, LB, 2015) |
| "The study relies on the development of a methodology for assessing the determinants that comprise the overall leukemia risk due to benzene exposure and how these are affected by outdoor and indoor air quality regulation." | 3.79 | A methodological frame for assessing benzene induced leukemia risk mitigation due to policy measures. ( Gotti, A; Karakitsios, SP; Kassomenos, PA; Pilidis, GA; Sarigiannis, DΑ, 2013) |
| "Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia." | 3.78 | Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012) |
| "Benzene, an established cause of acute myeloid leukemia (AML), may also cause one or more lymphoid malignancies in humans." | 3.77 | Global gene expression profiling of a population exposed to a range of benzene levels. ( Hubbard, AE; Lan, Q; Li, G; McHale, CM; Porter, KE; Portier, CJ; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Thomas, R; Vermeulen, R; Yin, S; Zhang, L, 2011) |
| "Evidence suggests that de novo, therapy-related and benzene-induced acute myeloid leukemias (AML) occur via similar cytogenetic and genetic pathways, several of which involve aneuploidy, the loss or gain of chromosomes." | 3.77 | Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene. ( Guo, W; Hubbard, AE; Ji, Z; Lan, Q; Li, G; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2011) |
| " The approach is demonstrated with 2 studies of leukemia in benzene-exposed workers, one conducted in the Australian petroleum industry (1981-1999) and one conducted in a US rubber hydrochloride production factory in Ohio (1940-1996)." | 3.77 | The impact of saturable metabolism on exposure-response relations in 2 studies of benzene-induced leukemia. ( Glass, DC; Kromhout, H; Portengen, L; Rappaport, SM; Vermeulen, R; Vlaanderen, J, 2011) |
| "Benzene is a well-known environmental pollutant that can induce hematotoxicity, aplastic anemia, acute myelogenous leukemia, and lymphoma." | 3.77 | Differential gene expression profiles of human leukemia cell lines exposed to benzene and its metabolites. ( Kim, YJ; Ryu, JC; Sarma, SN, 2011) |
| " The results of several independent epidemiologic studies of occupational cohorts with benzene exposure and the development of leukemia will be presented in order to find common aspects." | 3.76 | Implications of latency period between benzene exposure and development of leukemia--a synopsis of literature. ( Triebig, G, 2010) |
| "Previous evaluations of the shape of the benzene-leukemia exposure-response curve (ERC) were based on a single set or on small sets of human occupational studies." | 3.76 | Flexible meta-regression to assess the shape of the benzene-leukemia exposure-response curve. ( Kromhout, H; Lan, Q; Portengen, L; Rothman, N; Vermeulen, R; Vlaanderen, J, 2010) |
| " As a basis for additionally coordinating and focusing research on critical data gaps in a risk assessment context, five key events in the mode of action for benzene-induced leukemia are proposed: (1) benzene metabolism via Cytochrome P450, (2) the interaction of benzene metabolites with target cells in the bone marrow, (3) formation of initiated, mutated target cells, (4) selective proliferation of the mutated cells and (5) production of leukemia." | 3.76 | Proposed mode of action of benzene-induced leukemia: Interpreting available data and identifying critical data gaps for risk assessment. ( Klaunig, JE; Meek, ME, 2010) |
| " Data on leukemia mortality and occupational exposure to benzene among rubber hydrochloride production workers in Ohio (1940-1996) were analyzed by using this approach." | 3.75 | Multistage modeling of leukemia in benzene workers: a simple approach to fitting the 2-stage clonal expansion model. ( Richardson, DB, 2009) |
| "Epidemiological studies show that benzene exposure is associated with an increased incidence of leukemia and perhaps lymphoma." | 3.74 | Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Li, G; Lu, W; Rothman, N; Smith, MT; Yang, W; Yin, S; Zhang, L, 2007) |
| "I evaluated variation in benzene-related leukemia with age at exposure and time since exposure." | 3.74 | Temporal variation in the association between benzene and leukemia mortality. ( Richardson, DB, 2008) |
| "To investigate the leukemia risk in a group of benzene exposed workers." | 3.73 | Leukemia risk in caprolactam workers exposed to benzene. ( de Cock, J; Drooge, H; Scheffers, T; Slangen, J; Swaen, GM, 2005) |
| "Although benzene induces leukemias in humans, the compound is not believed to generate chromosomal damage directly." | 3.73 | Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase II alpha: 1,4-hydroquinone is a topoisomerase II poison. ( Bender, RP; Lindsey, RH; Osheroff, N, 2005) |
| "A nested case-control study found that the excess of leukemia, identified among the male members of the Health Watch cohort, was associated with benzene exposure." | 3.73 | Health Watch exposure estimates: do they underestimate benzene exposure? ( Gibbons, C; Glass, DC; Gray, CN; Jolley, DJ; Sim, MR, 2005) |
| "The study attempted to add years of follow-up to an earlier study describing excess leukemia among workers exposed to benzene-based glues in a shoe-factory and to conduct a quantitative exposure assessment of the exposure to benzene and the risk of leukemia." | 3.72 | Exposure to benzene and risk of leukemia among shoe factory workers. ( Consonni, D; Quinn, M; Seniori Costantini, A; Zappa, M, 2003) |
| "We found an excess risk of leukemia associated with cumulative benzene exposures and benzene exposure intensities that were considerably lower than reported in previous studies." | 3.72 | Leukemia risk associated with low-level benzene exposure. ( Adams, GG; Bisby, JA; Fritschi, L; Gibbons, C; Glass, DC; Gray, CN; Jolley, DJ; Manuell, R; Sim, MR, 2003) |
| "In 1974, Professor Muzaffer Aksoy established a link to leukemia in humans as a result of occupational exposure to benzene." | 3.72 | Story of benzene and leukemia: epidemiologic approach of Muzaffer Aksoy. ( Akbulut, T; Dikici, M; Sabuncu, H; Yaris, E; Yaris, F, 2004) |
| "Chronic exposure to benzene results in progressive decline of hematopoietic function and may lead to the onset of various disorders, including aplastic anemia, myelodysplastic syndrome, and leukemia." | 3.72 | Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression. ( Abernethy, DJ; Faiola, B; Fuller, ES; Pluta, L; Recio, L; Rose, J; Wong, VA, 2004) |
| "Many occupational and environmental exposures have been implicated in the etiology of leukemia, but only a few, such as benzene, are well-established leukemogens." | 3.71 | Leukemia in relation to occupational exposures to benzene and other agents: a case-control study nested in a cohort of gas and electric utility workers. ( Chevalier, A; Crinquand-Calastreng, A; Goldberg, M; Guénel, P; Imbernon, E, 2002) |
| "Previous studies of a cohort of rubber hydrochloride workers indicated an association between benzene exposure and excess mortality from leukemia and multiple myeloma." | 3.71 | Benzene exposure and hematopoietic mortality: A long-term epidemiologic risk assessment. ( Hornung, RW; Rinsky, RA; Silver, SR; Tseng, CY, 2002) |
| "To study the relationship between glutathione S transferase M1(GST mu) gene deletion and leukemia in workers exposed to benzene." | 3.71 | [Study on the relationship between glutathione S transferase mu gene deletion and leukemia in workers exposed to benzene]. ( Li, C; Long, Y; Wang, W; Xiang, C; Zhan, C, 2002) |
| " Average concentrations of benzene and nitrogen dioxide (indicators of traffic-related air pollution) were calculated for the relevant period, and exposures to air pollution during pregnancy and during childhood were calculated separately." | 3.71 | Air pollution from traffic at the residence of children with cancer. ( Hertel, O; Olsen, JH; Raaschou-Nielsen, O; Thomsen, BL, 2001) |
| "Chronic exposure to benzene is associated with hematotoxicity and acute myelogenous leukemia." | 3.71 | Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha. ( Baker, RK; Irons, RD; Kroll, DJ; Kurz, EU; Pyatt, DW, 2001) |
| "The excess risk of leukemia in rubber industry was considered to be real and attributed to the exposure to solvents, particularly benzene." | 3.71 | Leukemia mortality and occupational exposure to rubber: a nested case-control study. ( Li, K; Yu, S, 2002) |
| " Concentrations of benzene and nitrogen dioxide (indicators of traffic-related air pollution) were calculated for the relevant residential periods, and combined into exposures to air pollution during pregnancy and childhood, respectively." | 3.71 | [Traffic-related air pollution at the place of residence and risk of cancer among children]. ( Hertel, O; Olsen, JH; Raaschou-Nielsen, O; Thomsen, BL, 2002) |
| "Cigarette smoking is associated with an increased risk of leukemia; benzene, an established leukemogen, is present in cigarette smoke." | 3.70 | The contribution of benzene to smoking-induced leukemia. ( Ball, LM; Duell, EJ; Hertz-Picciotto, I; Korte, JE; Schulz, MR, 2000) |
| "A matched case-control study of leukemia risk in relation to the temporal pattern of benzene exposures was performed using data from the National Institute of Occupational Safety and Health." | 3.70 | Leukemia after exposure to benzene: temporal trends and implications for standards. ( Finkelstein, MM, 2000) |
| "Many risk assessments for leukemia associated with benzene exposure have been based on the mortality experience of the rubber hydrochloride worker cohort." | 3.69 | Benzene exposure assessment in rubber hydrochloride workers: a critical evaluation of previous estimates. ( Rinsky, RA; Utterback, DF, 1995) |
| "It is widely recognized that exposure to benzene is a risk factor for leukemia; however, much remains to be clarified about the possible long-term health effects of exposures to low concentrations of benzene." | 3.69 | Gasoline consumption and leukemia mortality and morbidity in 19 European countries: an ecological study. ( Slangen, JJ; Swaen, GM, 1995) |
| "Gender differences in risk for leukemia and other selected and combined disease categories were examined by major occupational category for 74,828 benzene-exposed workers compared to 35,805 unexposed workers from 12 cities in China." | 3.69 | Gender differences in hematopoietic and lymphoproliferative disorders and other cancer risks by major occupational group among workers exposed to benzene in China. ( Chow, WH; Dosemeci, M; Hayes, RB; Jiang, ZL; Li, GL; Linet, MS; Wacholder, S; Wang, YZ; Yin, SN; Zhang, WU, 1994) |
| "The detailed work histories of the individual workers composing the Pliofilm cohort represent a unique resource for estimating the dose-response for leukemia that may follow occupational exposure to benzene." | 3.69 | Leukemia risk associated with benzene exposure in the pliofilm cohort. II. Risk estimates. ( Brett, SM; Chinchilli, VM; Paxton, MB; Rodricks, JV, 1994) |
| "This report updates the risk assessment by Crump and Allen (1984) for benzene-induced leukemia that was used by OSHA (1987) to support its reduction of the permissible exposure limit (PEL) to 1 ppm and that also was the basis for EPA's (1985) interim "unit risk" for benzene." | 3.69 | Risk of benzene-induced leukemia: a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates. ( Crump, KS, 1994) |
| "Retrospective, quantitative estimates of exposure to 1,3-butadiene, styrene and benzene were developed for a follow-up study of leukemia mortality among 16610 subjects employed at six North American styrene-butadiene rubber manufacturing plants (418846 person-years, 58 leukemia deaths)." | 3.69 | Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry. ( Cole, P; Delzell, E; Hovinga, M; Julian, J; Larson, R; Macaluso, M; Muir, D; Sathiakumar, N, 1996) |
| "Risks of leukaemia, non-Hodgkin's lymphoma, and multiple myeloma were not associated with increasing cumulative exposure to benzene or total hydrocarbons." | 3.69 | Lymphohaematopoietic malignancies and quantitative estimates of exposure to benzene in Canadian petroleum distribution workers. ( Armstrong, TW; Huebner, WW; Katz, AM; Nicolich, MJ; Pearlman, ED; Schnatter, AR; Thompson, FS, 1996) |
| "This study was conducted to evaluate the relationship between leukemia occurrence and long-term, low-level benzene exposures in petroleum distribution workers." | 3.69 | The relationship between low-level benzene exposure and leukemia in Canadian petroleum distribution workers. ( Armstrong, TW; Huebner, WW; Katz, AM; Nicolich, MJ; Pearlman, ED; Schnatter, AR; Thompson, LS, 1996) |
| "This report updates the risk assessment by Crump and Allen for benzene-induced leukemia that was based on a cohort exposed to benzene in the manufacture of Pliofilm." | 3.69 | Risk of benzene-induced leukemia predicted from the Pliofilm cohort. ( Crump, KS, 1996) |
| "Benzene is an established cause of leukemia in adults, especially acute non-lymphocytic leukemia (ANLL)." | 3.69 | Environmental exposure to gasoline and leukemia in children and young adults--an ecology study. ( Järvholm, B; Nordlinder, R, 1997) |
| " The association of benzene-related leukopenia with leukemia is being studied in benzene-exposed workers." | 3.68 | Biomarkers in occupational cancer epidemiology: considerations in study design. ( Hayes, RB, 1992) |
| " Werner Lutz and colleagues illustrate the situation using the leukemia-inducing chemical benzene as an example." | 3.68 | The real role of risk assessment in cancer risk management. ( Lutz, WK; Poetzsch, J; Schlatter, C; Schlatter, J, 1991) |
| "Benzene exposure can cause leukemia, aplastic anemia, and possibly lymphoma." | 3.67 | Quantitative assessment of lives lost due to delay in the regulation of occupational exposure to benzene. ( Landrigan, PJ; Nicholson, WJ, 1989) |
| "To assess quantitatively the association between benzene and leukemia, we evaluated the rate of mortality experienced by a cohort occupationally exposed to benzene." | 3.67 | Benzene and leukemia: an epidemiologic risk assessment. ( Rinsky, RA, 1989) |
| "To assess quantitatively the association between benzene exposure and leukemia, we examined the mortality rate of a cohort with occupational exposure to benzene." | 3.67 | Benzene and leukemia. An epidemiologic risk assessment. ( Filloon, TG; Hornung, R; Landrigan, PJ; Okun, AH; Rinsky, RA; Smith, AB; Young, RJ, 1987) |
| " Specific examples are provided that involve asbestos-induced mesothelioma and leukemia caused by benzene exposure." | 3.67 | Time-related factors in quantitative risk assessment. ( Allen, BC; Crockett, PW; Crump, KS; Howe, RB, 1987) |
| "Today there seems to be sufficient data to incriminate benzene as a potent carcinogenic agent causing leukemia, malignant lymphoma, multiple myeloma and lung cancer, as well as numerous disorders of the bone marrow depression." | 3.67 | Benzene as a leukemogenic and carcinogenic agent. ( Aksoy, M, 1985) |
| "Until recently, the incidence of benzene carcinogenicity was based only on the association between benzene occupational exposure and human leukemia, with many limited case reports and scanty epidemiological data." | 3.66 | Benzene: a multipotential carcinogen. Results of long-term bioassays performed at the Bologna Institute of Oncology. ( Conti, B; Cotti, G; Maltoni, C, 1983) |
| "Benzene has the sad privilege of being the only industrial chemical inducing leukemia in susceptible individuals chronically exposed to its vapors." | 3.66 | An hypothesis for the induction of leukemia by benzene. ( Braier, L, 1983) |
| "To evaluate the possible association between occupational exposure to benzene and subsequent death from leukemia, the National Institute for Occupational Safety and Health (NIOSH) conducted a retrospective cohort mortality study of workers who had been exposed to benzene in the manufacture of rubber hydrochloride at two locations in Ohio." | 3.66 | Leukemia in benzene workers. ( Rinsky, RA; Smith, AB; Young, RJ, 1981) |
| "The distribution of various types of leukemia due to chronic exposure to benzene is described in a series comprising 34 cases." | 3.65 | Types of leukemia in chronic benzene poisoning. A study in thirty-four patients. ( Aksoy, M; Dinçol, G; Erdem, S, 1976) |
| "Benzene is a well-known cause of adult leukemia." | 3.01 | Linking Benzene, in Utero Carcinogenicity and Fetal Hematopoietic Stem Cell Niches: A Mechanistic Review. ( Abd Hamid, Z; Budin, SB; Taib, IS; Yusoff, NA, 2023) |
| "Benzene is an occupational and environmental toxicant, causing hematopoietic damage." | 2.82 | Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis. ( Cong, X; Pu, Y; Sun, Q; Wang, B; Xu, S; Zhang, J, 2022) |
| "Benzene is a well-studied substance that is generally considered a genotoxic carcinogen and is known to cause leukemia." | 2.66 | Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene. ( Ball, NS; Dearfield, KL; Gollapudi, BB; Johnson, GE; Luijten, M; Madia, F; Peel, L; Pfuhler, S; Settivari, RS; Ter Burg, W; van Benthem, J; White, PA, 2020) |
| "Benzene is an environmental toxicant found in many consumer products." | 2.66 | Benzene and its effects on cell signaling pathways related to hematopoiesis and leukemia. ( Lu, PCW; Shahbaz, S; Winn, LM, 2020) |
| "We review approaches for characterizing "peak" exposures in epidemiologic studies and methods for incorporating peak exposure metrics in dose-response assessments that contribute to risk assessment." | 2.61 | Peak Exposures in Epidemiologic Studies and Cancer Risks: Considerations for Regulatory Risk Assessment. ( Checkoway, H; Dell, LD; Gentry, PR; Lees, PSJ; Mundt, KA, 2019) |
| "Benzene is a volatile aromatic hydrocarbon solvent and is known as one of the predominant air pollutants in the environment." | 2.53 | Benzene exposure is associated with epigenetic changes (Review). ( Costa, C; Fenga, C; Gangemi, S, 2016) |
| "It has been shown, that benzene causes chromosomal aberrations, sister chromatid exchanges and micronuclei in lymphocytes of exposed workers." | 2.42 | Chromosomal aberrations in humans induced by benzene. ( Dianovskỳ, J; Holecková, B; Piesová, E; Sivikova, K, 2004) |
| " People vary greatly in their susceptibility to adverse health outcomes from benzene exposure." | 2.41 | [Individual susceptibility to hematotoxicity from benzene exposure and the genetic polymorphism of metabolic enzymes]. ( Chen, Y; Li, G; Yin, S, 2002) |
| "Risk estimates and cause and effect determinations are directly dependent on exposure and dose-response relationships." | 2.40 | An evaluation of modeled benzene exposure and dose estimates published in the Chinese-National Cancer Institute collaborative epidemiology studies. ( Budinsky, RA; DeMott, RP; Schell, JD; Wernke, MJ, 1999) |
| "The meta-SMR for acute myeloid leukemia was 0." | 2.39 | Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996) |
| " Its goals are: (i) to introduce the qualitative biological background needed for detailed quantitative dose-response modeling of benzene cancer risks; and (ii) to survey a rapidly evolving area of research that shows promise of producing fundamental insights into the mechanisms of toxicity and carcinogenesis for several chemicals--benzene and perhaps phenols, catechols, and other hydroxylated ring hydrocarbons--in the decade ahead." | 2.38 | Biological basis of chemical carcinogenesis: insights from benzene. ( Cox, LA, 1991) |
| "The clinical and hematologic picture of aplastic anemia resulting from benzene exposure is not different from classical aplastic anemia; in some cases, mild bilirubinemia, changes in osmotic fragility, increase in lactic dehydrogenase and fecal urobilinogen, and occasionally some neurological abnormalities are found." | 2.38 | Hematotoxicity and carcinogenicity of benzene. ( Aksoy, M, 1989) |
| " The dose-response relationship is strongly nonlinear." | 2.38 | Consistencies and inconsistencies underlying the quantitative assessment of leukemia risk from benzene exposure. ( Byrd, DM; Grunwald, H; Lamm, SH; Walters, AS; Wilson, R, 1989) |
| "Benzene is a known human carcinogen and one of the ten chemicals of major public health concern identified by the World Health Organization." | 1.91 | Health Risk Assessment in Children Occupationally and Para-Occupationally Exposed to Benzene Using a Reverse-Translation PBPK Model. ( Farías, P; Lajous, M; Pech, K; Pérez-Herrera, N; Vértiz-Hernández, ÁA, 2023) |
| "Benzene is a known hematotoxic and leukemogenic chemical." | 1.91 | Benzene metabolite hydroquinone enhances self-renewal and proliferation of preleukemic cells through the Ppar-γ pathway. ( Cheng, X; Li, J; Lian, N; Lu, Y; Sui, P; Wang, QF; Xing, C; Xu, P; Zhou, J, 2023) |
| "Benzene is a ubiquitous, occupational, and environmental hematotoxic and leukemogen." | 1.62 | Toxicity in hematopoietic stem cells from bone marrow and peripheral blood in mice after benzene exposure: Single-cell transcriptome sequencing analysis. ( Ji, S; Pu, Y; Sun, R; Xu, K; Yin, L; Yu, L; Zhang, J, 2021) |
| "Benzene was used for inducing leukemia in experimental rats." | 1.62 | Daphnetin exerts an anticancer effect by attenuating the pro-inflammatory cytokines. ( Hu, P; Li, H; Liu, R; Pei, Q; Yang, T; Zhang, H, 2021) |
| "Benzene was largely banned from Danish workplaces after 1975, thus this case-control study focused on the immediately prior years." | 1.51 | Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study. ( Contreras, ZA; Hansen, J; He, D; Heck, JE; Olsen, J; Ritz, B, 2019) |
| "We identified incident cancer cases through record linkage with the Swiss Childhood Cancer Registry." | 1.46 | Parental occupational exposure to benzene and the risk of childhood cancer: A census-based cohort study. ( Huss, A; Kuehni, CE; Lupatsch, JE; Rischewski, J; Schindera, C; Spoerri, A; Spycher, BD; Vermeulen, R, 2017) |
| "Benzene is an established myeloid leukemogen and probable lymphomagen." | 1.43 | Comparison of hematological alterations and markers of B-cell activation in workers exposed to benzene, formaldehyde and trichloroethylene. ( Bassig, BA; Blair, A; Freeman, LE; Ge, Y; Guo, W; Hayes, RB; Hosgood, HD; Hu, W; Huang, H; Ji, Z; Lan, Q; Li, G; Li, L; Purdue, MP; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Shen, M; Smith, MT; Tang, X; Vermeulen, R; Wu, B; Xie, Y; Yin, S; Yue, F; Zhang, L, 2016) |
| "Leukemia was induced by intravenous injection of 0." | 1.40 | Chemopreventive and anti-leukemic effects of ethanol extracts of Moringa oleifera leaves on wistar rats bearing benzene induced leukemia. ( Adedeji, AL; Adedosu, OT; Akanni, EO; Olaniran, OI; Oloke, JK, 2014) |
| "Frequent karyotypic changes were trisomy 8 (9." | 1.38 | Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience. ( Alimena, G; Breccia, M; Finsinger, P; Latagliata, R; Loglisci, G; Nanni, M; Petrucci, L; Salaroli, A; Santopietro, M; Serrao, A; Volpicelli, P, 2012) |
| "National mortality rates and cancer registration (incidence) rates were used to calculate standardised mortality ratios and standardised registration ratios." | 1.33 | Cancer risks in a historical UK cohort of benzene exposed workers. ( Doll, R; Kinlen, LJ; Sorahan, T, 2005) |
| "The symposium overview describes the recent succession of scientific meetings to further understand the adverse effects of benzene." | 1.33 | International symposium: Recent advances in benzene toxicity. ( Bird, MG; Greim, H; Rice, JM; Snyder, R, 2005) |
| "Benzene is an established human and animal carcinogen." | 1.33 | Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene. ( Eastmond, DA; Hasegawa, L; Mondrala, ST, 2005) |
| "We found a statistically significant increased risk for acute myeloid leukemia (AML) associated with active smoking, with a clear dose-response relationship and an adjusted odds ratio (OR) of 1." | 1.33 | Lifestyle factors and the risk of adult leukemia in Canada. ( Abdous, B; Auger, P; Johnson, KC; Kasim, K; Levallois, P, 2005) |
| " Here, we describe a human physiologically-based pharmacokinetic (PBPK) model that quantifies tissue doses of benzene and its key metabolites, benzene oxide, phenol, and hydroquinone after inhalation and oral exposures." | 1.33 | Physiologically-based pharmacokinetic modeling of benzene in humans: a Bayesian approach. ( Pekari, K; Rappaport, S; Riihimaki, V; Rothman, N; Schlosser, PM; Tran, HT; Waidyanatha, S; Yokley, K, 2006) |
| "Benzene is an organic solvent that has been used in industry for about 100 years throughout the world." | 1.33 | Progress of epidemiological and molecular epidemiological studies on benzene in China. ( Li, G; Yin, S, 2006) |
| "The leukemias were not restricted to acute myelogenous subtypes, and they occurred predominantly among workers hired before 1950 at exposure levels lower than previously reported." | 1.30 | Cancer mortality among workers with benzene exposure. ( Buckley, CF; Collins, JJ; Ireland, B; Riordan, SG, 1997) |
| "Leukemia is the most common cancer in children." | 1.30 | Biomarkers of leukemia risk: benzene as a model. ( Smith, MT; Zhang, L, 1998) |
| "Benzene, a recognised cause of haematological cancer, is a component of petrol." | 1.29 | Haematopoietic cancer mortality among vehicle mechanics. ( Hunting, KL; Kalavar, SS; Longbottom, H; Schwartz, E; Stern, F; Welch, LS, 1995) |
| "The fact that leukemia has not been observed in any individual who started employment in Pliofilm production after 1950 suggests that the observed leukemia cases could be a response to very high levels of benzene exposure that occurred during the early years of this manufacturing process." | 1.29 | Leukemia risk associated with benzene exposure in the pliofilm cohort: I. Mortality update and exposure distribution. ( Brett, SM; Chinchilli, VM; Paxton, MB; Rodricks, JV, 1994) |
| "A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1." | 1.29 | An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group. ( Blot, WJ; Chow, WH; Dosemeci, M; Hayes, RB; Li, DG; Li, GL; Linet, MS; Travis, LB; Wacholder, S; Yin, SN; Zhang, ZN, 1996) |
| " Neither the Paustenbach nor the Crump exposures gave dose-response estimates as steep as that resulting from the Rinsky exposures." | 1.29 | Leukemia risk associated with benzene exposure in the Pliofilm cohort. ( Paxton, MB, 1996) |
| "For certain cancers, increased mortality was noted among benzene-exposed males in comparison with that among unexposed males; the standardized mortality ratios (SMR) were elevated for leukemia (SMR = 5." | 1.28 | A retrospective cohort study of leukemia and other cancers in benzene workers. ( Chen, YJ; Fu, ZI; Jin, C; Li, GL; Luo, SJ; Tain, FD; Wang, GC; Ye, PZ; Yin, SN; Zhang, JZ, 1989) |
| "Benzene is a well documented carcinogen for the hematic and lymphopoietic system, and experimental research confirms its carcinogenicity for tumors of other sites." | 1.28 | Aplastic anemia, leukemia and other cancer mortality in a cohort of shoe workers exposed to benzene. ( Buiatti, E; Kaldor, JM; Miligi, L; Paci, E; Petrioli, G; Pucci, N; Scarpelli, A; Seniori Costantini, AS; Simonato, L; Winkelmann, R, 1989) |
| "Benzene has been known to be a bone marrow poison for almost a century." | 1.27 | Benzene: epidemiologic observations of leukemia by cell type and adverse health effects associated with low-level exposure. ( Infante, PF; White, MC, 1983) |
| "The prevalence of benzene induced aplastic anaemia in shoemakers was about 5." | 1.27 | Occupational exposure to benzene in China. ( Du, C; Jin, C; Li, Q; Liu, Y; Tian, F; Yin, SN, 1987) |
| "Although deaths due to malignant neoplasms were fewer than expected for the total cohort, an increase in lymphatic leukemia was observed among a subgroup of employees who had exposure to polymer extrusion fumes, solvents, and colorants." | 1.26 | A mortality survey of employees engaged in the development or manufacture of styrene-based products. ( Kolesar, RC; Ott, MG; Scharnweber, HC; Schneider, EJ; Venable, JR, 1980) |
| " Given a similar degree of exposure, why do some workers remain apparently unaffected, while others develop alterations of the hemopoietic system? It is hypothesized that inadequate nutritional status of possibly several nutrients including iron, selenium, methionine and ascorbic acid may enhance susceptibility to adverse effects caused by benzene." | 1.26 | Does nutritional status affect benzene induced toxicity and/or leukemia? ( Calabrese, EJ, 1980) |
| "Benzene is a major commodity chemical of great value to industry." | 1.26 | Benzene in the workplace. ( Bernath, T; Brief, RS; Lynch, J; Scala, RA, 1980) |
| "The number of observed deaths from all cancers was appreciably less than expected (O = 1147, E = 1286." | 1.26 | The influence of occupation on health--some results from a study in the UK oil industry. ( Alderson, M; Rushton, L, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 172 (45.03) | 18.7374 |
| 1990's | 64 (16.75) | 18.2507 |
| 2000's | 79 (20.68) | 29.6817 |
| 2010's | 48 (12.57) | 24.3611 |
| 2020's | 19 (4.97) | 2.80 |
| Authors | Studies |
|---|---|
| Mazzei, A | 1 |
| Konstantinoudis, G | 1 |
| Kreis, C | 1 |
| Diezi, M | 1 |
| Ammann, RA | 1 |
| Zwahlen, M | 1 |
| Kühni, C | 1 |
| Spycher, BD | 2 |
| Sun, Q | 1 |
| Wang, B | 1 |
| Xu, S | 1 |
| Cong, X | 1 |
| Pu, Y | 3 |
| Zhang, J | 2 |
| Guo, X | 2 |
| Zhang, L | 9 |
| Wang, J | 2 |
| Zhang, W | 2 |
| Ren, J | 2 |
| Chen, Y | 3 |
| Zhang, Y | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Scientific Protocol for the Study of Leukemia and Other Hematologic Diseases Among Clean-up Workers in Ukraine Following the Chernobyl Accident[NCT00341016] | 1,779 participants (Actual) | Observational | 1996-08-26 | Completed | |||
| A Case - Cohort Study of Hematopoietic Malignancies and Related Disorders and Lung Cancer in Benzene-Exposed Workers in China[NCT00559065] | 3,260 participants (Actual) | Observational | 2006-07-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
88 reviews available for benzene and Leukemia
| Article | Year |
|---|---|
Childhood cancer and residential proximity to petrol stations: a nationwide registry-based case-control study in Switzerland and an updated meta-analysis.
Topics: Adolescent; Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Ex | 2022 |
Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis.
Topics: Benzene; Bibliometrics; Child; Humans; Leukemia; Research | 2022 |
Linking Benzene, in Utero Carcinogenicity and Fetal Hematopoietic Stem Cell Niches: A Mechanistic Review.
Topics: Benzene; Carcinogenesis; Child; Female; Fetus; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leuk | 2023 |
Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene.
Topics: Animals; Benzene; Carcinogens; DNA Damage; Environmental Exposure; Humans; Leukemia; Mutagenesis; Mu | 2020 |
Residential exposure to petrochemical industrial complexes and the risk of leukemia: A systematic review and exposure-response meta-analysis.
Topics: Air Pollutants; Benzene; Chemical Industry; Environmental Exposure; Humans; Incidence; Leukemia; Pet | 2020 |
Benzene and its effects on cell signaling pathways related to hematopoiesis and leukemia.
Topics: Benzene; Carcinogens; Cell Differentiation; Environmental Exposure; Hematopoiesis; Humans; Leukemia; | 2020 |
Peak Exposures in Epidemiologic Studies and Cancer Risks: Considerations for Regulatory Risk Assessment.
Topics: Acrylonitrile; Air Pollutants; Benzene; Environmental Exposure; Epidemiologic Studies; Ethylene Oxid | 2019 |
Benzene exposure is associated with epigenetic changes (Review).
Topics: Benzene; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Histones; Humans; Leukemia; M | 2016 |
A review of risk factors for childhood leukemia.
Topics: Alcohol Drinking; Benzene; Child; Environment; Humans; Leukemia; Radiation, Ionizing; Risk Factors; | 2016 |
[Paradigm change in the assessment of myeloid and lymphoid neoplasms associated with occupational benzene exposure].
Topics: Air Pollutants, Occupational; Benzene; Body Burden; Cross-Sectional Studies; Expert Testimony; Germa | 2009 |
A review of the potential association between childhood leukemia and benzene.
Topics: Benzene; Child; Environmental Exposure; Humans; Leukemia; Leukemia, Myeloid, Acute; Risk Factors | 2010 |
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis.
Topics: Benzene; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, B | 2010 |
Occupational lymphohematopoietic cancer in Korea.
Topics: Adult; Benzene; Cohort Studies; Female; Humans; Incidence; Leukemia; Leukemia, Radiation-Induced; Ma | 2010 |
Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment.
Topics: Animals; Benzene; Hematopoietic Stem Cells; Humans; Leukemia; Risk Assessment; Systems Biology; Toxi | 2012 |
Proposal on limits for chemical exposure in saturation divers' working atmosphere: the case of benzene.
Topics: Benzene; Diving; Environmental Monitoring; Leukemia; Occupational Exposure; Oxygen | 2012 |
Stem cell and benzene-induced malignancy and hematotoxicity.
Topics: Apoptosis; Benzene; Bone Marrow Cells; DNA Repair; Epigenesis, Genetic; Hematopoietic Stem Cells; Hu | 2012 |
Leukemia and benzene.
Topics: Animals; Benzene; Bone Marrow; Environmental Exposure; Hematopoiesis; Hematopoietic Stem Cells; Huma | 2012 |
[Individual susceptibility to hematotoxicity from benzene exposure and the genetic polymorphism of metabolic enzymes].
Topics: Air Pollutants, Occupational; Benzene; Cytochrome P-450 CYP2E1; Genetic Predisposition to Disease; G | 2002 |
Causal models of leukaemia and lymphoma.
Topics: Autoimmunity; Benzene; Biomarkers; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Models, Bio | 2004 |
Benzene and hematopoietic malignancies.
Topics: Benzene; Environmental Exposure; Humans; Leukemia; Lymphoma; Occupational Exposure | 2004 |
Chromosomal aberrations in humans induced by benzene.
Topics: Benzene; Chromosome Aberrations; Cytogenetic Analysis; DNA Damage; Humans; In Situ Hybridization, Fl | 2004 |
[Risk of leukemia related with benzene and chromosomal aberrations.].
Topics: Benzene; Carcinogens; Chromosome Aberrations; Genetic Predisposition to Disease; Humans; Leukemia | 2005 |
Review of the literature on benzene exposure and leukemia subtypes.
Topics: Air Pollutants, Occupational; Benzene; Case-Control Studies; Chemical Industry; Cohort Studies; Huma | 2005 |
Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity.
Topics: Animals; Benzene; Bone Marrow; Genetic Predisposition to Disease; Humans; Hyperplasia; Leukemia; Mic | 2005 |
Functions and distribution of NQO1 in human bone marrow: potential clues to benzene toxicity.
Topics: Animals; Benzene; Bone Marrow; Genetic Predisposition to Disease; Genotype; Humans; Leukemia; NAD(P) | 2005 |
[Review of leukemia induced by benzene poisoning].
Topics: Benzene; Humans; Leukemia | 2005 |
The application of epidemiology to the prevention of occupational cancer.
Topics: Air Pollutants, Occupational; Animals; Benzene; Epidemiology; Humans; Leukemia; Male; Maximum Allowa | 1984 |
Hematological, myelotoxic, clastogenic, carcinogenic, and leukemogenic effects of benzene.
Topics: Animals; Benzene; Bone Diseases; Carcinogens; Chromosome Aberrations; Environmental Pollutants; Hodg | 1982 |
Cytotoxic drugs and leukaemogenesis.
Topics: Adult; Aged; Arsenic; Benzene; Bone Marrow; Breast Neoplasms; Female; Hodgkin Disease; Humans; Leuke | 1980 |
Chemically induced leukemia in humans.
Topics: Benzene; Chlorambucil; Chloramphenicol; Cyclophosphamide; Humans; Leukemia; Melphalan; Phenylbutazon | 1981 |
Occupational exposure to benzene: a review of carcinogenic and related health effects following the U.S. Supreme Court decision.
Topics: Animals; Benzene; Carcinogens; Chromosome Aberrations; Dose-Response Relationship, Drug; Epidemiolog | 1980 |
Cell-type-specific leukemia analyses in a combined cohort of more than 208,000 petroleum workers in the United States and the United Kingdom, 1937-1989.
Topics: Benzene; Cohort Studies; Humans; Industry; Leukemia; Occupational Exposure; Petroleum; Risk Assessme | 1995 |
[The permissible concentrations of benzene in the atmospheric air of populated locations].
Topics: Air Pollutants; Benzene; Chromosome Aberrations; Drug Interactions; Humans; Leukemia; Maximum Allowa | 1994 |
Hematopoietic malignancies and related disorders among benzene-exposed workers in China.
Topics: Adult; Air Pollutants, Occupational; Anemia, Aplastic; Benzene; China; Cohort Studies; Female; Human | 1994 |
A perspective on benzene leukemogenesis.
Topics: Animals; Benzene; Benzene Derivatives; Carcinogens; Humans; Leukemia; Leukemia, Experimental | 1994 |
[Health risks of gasoline handling. Exposure to benzene can cause leukemia].
Topics: Benzene; Gasoline; Humans; Leukemia; Occupational Exposure; Risk Factors | 1993 |
The effects of benzene and other leukaemogenic agents on haematopoietic stem and progenitor cell differentiation.
Topics: Animals; Benzene; Carcinogens; Cell Differentiation; Cytokines; Hematopoietic Stem Cells; Humans; Le | 1996 |
Review of epidemiologic evidence on benzene and lymphatic and hematopoietic cancers.
Topics: Benzene; Hematologic Neoplasms; Humans; Leukemia; Lymphoma | 1997 |
An overview of benzene metabolism.
Topics: Animals; Benzene; Biotransformation; Bone Marrow; DNA Adducts; Humans; In Vitro Techniques; Leukemia | 1996 |
The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia.
Topics: Aneuploidy; Animals; Benzene; Carcinogens; Humans; Leukemia; Liver; Models, Biological; Phenols; Rec | 1996 |
The process of leukemogenesis.
Topics: Benzene; Carcinogens; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 5; Cocar | 1996 |
Clinical features of hematopoietic malignancies and related disorders among benzene-exposed workers in China. Benzene Study Group.
Topics: Adult; Benzene; China; Cohort Studies; Female; Follow-Up Studies; Humans; Leukemia; Lymphoma; Male; | 1996 |
Leukemia mortality by cell type in petroleum workers with potential exposure to benzene.
Topics: Benzene; Cohort Studies; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloge | 1996 |
Organic solvents and cancer.
Topics: Alcohol Drinking; Benzene; Biliary Tract Neoplasms; Carbon Tetrachloride; Carcinogens; China; Cohort | 1997 |
An evaluation of modeled benzene exposure and dose estimates published in the Chinese-National Cancer Institute collaborative epidemiology studies.
Topics: Air Pollutants, Occupational; Benzene; Carcinogens; China; Dose-Response Relationship, Drug; Humans; | 1999 |
Assessing the health risks of benzene: a report on the benzene state-of-the-science workshop.
Topics: Animals; Benzene; Bone Marrow Diseases; Carcinogens; Humans; Leukemia; Occupational Diseases; Occupa | 2000 |
Overview of the toxicology of benzene.
Topics: Animals; Benzene; Bone Marrow Diseases; Carcinogens; DNA Damage; Humans; Leukemia; Pancytopenia | 2000 |
Benzene-induced genotoxicity.
Topics: Animals; Benzene; Carcinogens; DNA; DNA Adducts; DNA Damage; Humans; Leukemia | 2000 |
Recent findings and new initiatives for epidemiologic research on benzene.
Topics: Benzene; Carcinogens; Extraction and Processing Industry; Humans; Leukemia; Neoplasms; Occupational | 2000 |
[Air pollution from traffic and the risk of tumors].
Topics: Adult; Air Pollution; Benzene; Benzo(a)pyrene; Carcinogens, Environmental; Child; Child, Preschool; | 2000 |
Chromosome damage from biological reactive intermediates of benzene and 1,3-butadiene in leukemia.
Topics: Benzene; Butadienes; Carcinogens; Chromosome Aberrations; Humans; Leukemia; Lymphoma; Risk Assessmen | 2001 |
The nature of chromosomal aberrations detected in humans exposed to benzene.
Topics: Adult; Aged; Aged, 80 and over; Benzene; Biomarkers; Carcinogens; Chromosome Aberrations; Female; Hu | 2002 |
Benzene and leukemia.
Topics: Animals; Benzene; Benzene Derivatives; Carcinogens; Chromosomes; DNA; Humans; Leukemia; Myelodysplas | 2002 |
Evaluation of the health effects of benzene inhalation.
Topics: Absorption; Air Pollutants; Animals; Benzene; Chemical Industry; Coal Mining; Coke; Dogs; Environmen | 1977 |
Genetic and environmental interactions.
Topics: Adult; Benzene; Carcinogens, Environmental; Carcinoma, Basal Cell; Child; Child, Preschool; DNA Repa | 1977 |
Benzene toxicity: a critical evaluation: hematotoxicity in humans.
Topics: Benzene; Blood Cells; Hematologic Diseases; Humans; Leukemia; Pancytopenia; Time Factors | 1977 |
Benzene--attempts to establish a lower exposure standard in the United States. A review.
Topics: Air Pollutants; Air Pollutants, Occupational; Anemia, Aplastic; Benzene; Carcinogens; Chromosome Abe | 1978 |
[Significance and limitations of the study of chromosome aberrations in occupational medicine].
Topics: Benzene; Chromosome Aberrations; Humans; Lead Poisoning; Leukemia; Leukemia, Radiation-Induced; Merc | 1978 |
Benzene and leukemia.
Topics: Benzene; Humans; Leukemia | 1976 |
Current concepts of chronic benzene toxicity.
Topics: Animals; Benzene; Humans; In Vitro Techniques; Leukemia; Mice; Neoplasms; Rabbits; Time Factors | 1975 |
The toxicity of benzene and its metabolism and molecular pathology in human risk assessment.
Topics: Anemia, Aplastic; Animals; Benzene; Bone Marrow; Chemical Phenomena; Chemistry; Humans; Leukemia; Ma | 1991 |
Benzene risk assessment: status of quantifying the leukemogenic risk associated with the low-dose inhalation of benzene.
Topics: Administration, Inhalation; Animals; Benzene; Dose-Response Relationship, Drug; Humans; Leukemia; Ri | 1991 |
Biological basis of chemical carcinogenesis: insights from benzene.
Topics: Animals; Benzene; Carcinogens; Female; Humans; Leukemia; Male; Mutagens | 1991 |
[Current status of knowledge of the effect of benzene. Impairment of blood and hemopoiesis].
Topics: Anemia, Aplastic; Benzene; Blood Cells; Hematopoiesis; Humans; Leukemia | 1990 |
Role of metabolism in benzene-induced myelotoxicity and leukemogenesis.
Topics: Animals; Benzene; Biotransformation; Bone Marrow; Catechols; Cells, Cultured; Cytochrome P-450 Enzym | 1990 |
[Occupational medicine monitoring of workers exposed to benzene].
Topics: Benzene; Germany, East; Humans; Leukemia; Mass Screening; Maximum Allowable Concentration; Occupatio | 1989 |
Setting environmental exposure standards: the role of the epidemiologist.
Topics: Benzene; Dose-Response Relationship, Drug; Environmental Exposure; Epidemiology; Health Policy; Huma | 1989 |
Benzene and leukaemia.
Topics: Animals; Benzene; Humans; Leukemia; Occupational Diseases | 1989 |
Hematotoxicity and carcinogenicity of benzene.
Topics: Anemia, Aplastic; Benzene; Hematologic Diseases; Humans; Leukemia; Neoplasms; Pancytopenia | 1989 |
Review and update of leukemia risk potentially associated with occupational exposure to benzene.
Topics: Benzene; Epidemiologic Methods; Humans; Leukemia; Models, Biological; Occupational Diseases; Risk | 1989 |
Consistencies and inconsistencies underlying the quantitative assessment of leukemia risk from benzene exposure.
Topics: Benzene; Humans; Leukemia; Leukemia, Myeloid, Acute; Occupational Diseases; Risk | 1989 |
Carcinogenicity of benzene, toluene and xylene: epidemiological and experimental evidence.
Topics: Animals; Benzene; Carcinogenicity Tests; Carcinogens, Environmental; Chromosomes; Humans; Leukemia; | 1988 |
Benzene and leukemia. A review of the literature and a risk assessment.
Topics: Benzene; Environmental Exposure; Humans; Leukemia; Maximum Allowable Concentration; Risk Factors | 1988 |
Benzene toxicity: studying a subject to death.
Topics: Benzene; Humans; Leukemia; Occupational Diseases; Politics; Risk; United States; United States Occup | 1987 |
Occupational health: the intersection between clinical medicine and public health.
Topics: Asbestos; Benzene; Epidemiologic Methods; History, 19th Century; History, 20th Century; Humans; Leuk | 1986 |
Chemical leukemogenesis: benzene as a model.
Topics: Animals; Benzene; Disease Models, Animal; Hematopoiesis; Humans; Leukemia; Leukemia, Experimental; M | 1987 |
Projections of leukemia risk associated with occupational exposure to benzene.
Topics: Air Pollutants, Occupational; Benzene; Humans; Leukemia; Occupational Diseases; Risk | 1985 |
[Debatable questions of the leukemogenic (blastomogenic) action of benzine].
Topics: Animals; Benzene; Chromosome Aberrations; DNA; Dose-Response Relationship, Drug; Humans; Immune Tole | 1985 |
[Benzene and leukemias and malignant lymphomas].
Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Europe; Humans; Leukemia; Lymphoma; North Ame | 1985 |
Environmental factors and leukaemia.
Topics: Acute Disease; Animals; Benzene; Cattle; Chromosome Aberrations; Electromagnetic Phenomena; Environm | 1985 |
Increased aromatics in motor fuels: a review of the environmental and health effects.
Topics: Air Pollution; Aldehydes; Animals; Benzene; Bone Marrow; Carcinogens; Central Nervous System; Chromo | 1974 |
Clinical epidemiology of leukemia.
Topics: Adolescent; Age Factors; Anemia, Pernicious; Benzene; Child, Preschool; Chloramphenicol; Chromosome | 1969 |
Recent developments in industrial carcinogens.
Topics: Amines; Animals; Arsenic Poisoning; Asbestos; Benzene; Carcinogens; Coal; Humans; Leukemia; Lung Neo | 1973 |
[Etiology of human leukemias].
Topics: Age Factors; Benzene; Cell Transformation, Neoplastic; Chloramphenicol; Hematopoietic Stem Cells; Hu | 1974 |
Chemical leukemogenesis in man.
Topics: Anemia, Aplastic; Benzene; Benzene Derivatives; Bone Marrow; Bone Marrow Cells; Chloramphenicol; Hum | 1974 |
[Leukemia-disposing factors in man].
Topics: Benzene; Child; Female; Humans; Leukemia; Leukemia, Radiation-Induced | 1974 |
[Current status of the problem of blood system change in chronic benzol poisoning (literature review)].
Topics: Anemia, Hypochromic; Ascorbic Acid Deficiency; Benzene; Blood Platelets; Bone Marrow; Bone Marrow Di | 1967 |
Progress in the leukemias.
Topics: Alkylating Agents; Androgens; Anemia, Hemolytic, Autoimmune; Benzene; Blood Transfusion; Bone Marrow | 1971 |
294 other studies available for benzene and Leukemia
| Article | Year |
|---|---|
Plasma metabolomics study reveals the critical metabolic signatures for benzene-induced hematotoxicity.
Topics: Acetylcysteine; Animals; Benzene; Bone Diseases, Metabolic; Fatty Acids; Humans; Leukemia; Leukocyte | 2022 |
Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells.
Topics: Benzene; Gene Regulatory Networks; Humans; Hydroquinones; K562 Cells; Leukemia; MicroRNAs; RNA, Mess | 2022 |
Combined efficacy of Cinnamomum zeylanicum and doxorubicin against leukemia through regulation of TRAIL and NF-kappa B pathways in rat model.
Topics: Animals; Apoptosis; Benzene; Cinnamomum zeylanicum; Doxorubicin; Leukemia; NF-kappa B; Oils, Volatil | 2022 |
Whole-exome sequencing identified recurrent and novel variants in benzene-induced leukemia.
Topics: Benzene; Exome Sequencing; Gene Frequency; Humans; Leukemia; Phosphatidylinositol 3-Kinases | 2023 |
Health Risk Assessment in Children Occupationally and Para-Occupationally Exposed to Benzene Using a Reverse-Translation PBPK Model.
Topics: Adult; Benzene; Carcinogenesis; Carcinogens; Child; Humans; Leukemia; Occupational Exposure; Risk As | 2023 |
Benzene metabolite hydroquinone enhances self-renewal and proliferation of preleukemic cells through the Ppar-γ pathway.
Topics: Animals; Benzene; Cell Proliferation; Hydroquinones; Leukemia; Mice; PPAR gamma | 2023 |
Residential proximity to petrol stations and risk of childhood leukemia.
Topics: Adolescent; Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Gasoline; Humans | 2023 |
LncRNA OBFC2A modulated benzene metabolites-induced autophagy and apoptosis by interacting with LAMP2.
Topics: Apoptosis; Autophagy; Benzene; Humans; Leukemia; Lysosomal-Associated Membrane Protein 2; RNA, Long | 2023 |
Leukemia Mortality among Benzene-Exposed Workers in Brazil (2006-2011).
Topics: Benzene; Brazil; Humans; Leukemia; Occupational Diseases; Occupational Exposure; Occupations | 2023 |
Toxicity in hematopoietic stem cells from bone marrow and peripheral blood in mice after benzene exposure: Single-cell transcriptome sequencing analysis.
Topics: Animals; Apoptosis; Benzene; Bone Marrow; Bone Marrow Cells; Environmental Pollutants; Hematopoietic | 2021 |
Genomic analysis of mutations in platelet mitochondria in a case of benzene-induced leukaemia: A case report.
Topics: Antineoplastic Agents; Benzene; Blood Platelets; Environmental Exposure; Female; Genome, Mitochondri | 2021 |
Daphnetin exerts an anticancer effect by attenuating the pro-inflammatory cytokines.
Topics: Animals; Antineoplastic Agents; Benzene; Cytokines; Inflammation; Leukemia; Neoplasm Proteins; Rats; | 2021 |
The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3).
Topics: Benzene; Benzoquinones; Cell Line; Cysteine; Histone-Lysine N-Methyltransferase; Histones; Humans; L | 2021 |
Parental occupational exposure to benzene and the risk of childhood cancer: A census-based cohort study.
Topics: Adolescent; Benzene; Censuses; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Infa | 2017 |
Adductomic signatures of benzene exposure provide insights into cancer induction.
Topics: Adult; Benzene; Benzene Derivatives; Carcinogenesis; Carcinogens; Cyclohexanes; Epoxy Compounds; Fem | 2018 |
Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study.
Topics: Adolescent; Adult; Benzene; Case-Control Studies; Child; Child, Preschool; Denmark; Female; Humans; | 2019 |
Benzene and leukemia: from scientific evidence to regulations. A historical example.
Topics: Benzene; Humans; Italy; Leukemia; Occupational Exposure; Solvents; Workplace | 2019 |
Good, the bad, and the ugly.
Topics: Benzene; Extraction and Processing Industry; Humans; Leukemia; Myelodysplastic Syndromes; Occupation | 2013 |
The bone marrow niche, stem cells, and leukemia: impact of drugs, chemicals, and the environment.
Topics: Animals; Benzene; Bone Marrow Cells; Drug-Related Side Effects and Adverse Reactions; Environmental | 2014 |
Chemopreventive and anti-leukemic effects of ethanol extracts of Moringa oleifera leaves on wistar rats bearing benzene induced leukemia.
Topics: Animals; Antineoplastic Agents; Benzene; Carcinogens; Ethanol; Glutathione; Hematologic Tests; Leuke | 2014 |
Lymphatic and hematopoietic cancers among benzene-exposed workers.
Topics: Benzene; Carcinogens; Cause of Death; Humans; Leukemia; Leukemia, Myeloid, Acute; Michigan; Myelodys | 2015 |
New mouse models mimic biology of human cancer.
Topics: Air Pollutants; Animals; Animals, Inbred Strains; Animals, Outbred Strains; Benzene; Carcinogens; En | 2015 |
Benzene exposure and risk of lymphohaematopoietic cancers in 25 000 offshore oil industry workers.
Topics: Adolescent; Adult; Aged; Benzene; Case-Control Studies; Cohort Studies; Follow-Up Studies; Hematolog | 2015 |
Non-radiation risk factors for leukemia: A case-control study among chornobyl cleanup workers in Ukraine.
Topics: Benzene; Case-Control Studies; Chernobyl Nuclear Accident; Hazardous Substances; Humans; Leukemia; L | 2015 |
Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells.
Topics: Benzene; Bone Marrow Cells; Chromosome Breakage; Core Binding Factor beta Subunit; Diethylnitrosamin | 2015 |
Traffic-related air pollution and risk for leukaemia of an adult population.
Topics: Adult; Aged; Aged, 80 and over; Air Pollution; Benzene; Case-Control Studies; Female; Humans; Leukem | 2016 |
Comparison of hematological alterations and markers of B-cell activation in workers exposed to benzene, formaldehyde and trichloroethylene.
Topics: Adult; B-Lymphocytes; Benzene; Biomarkers, Tumor; China; Female; Formaldehyde; Hemolytic Agents; Hum | 2016 |
Residential Proximity to Gasoline Stations and Risk of Childhood Leukemia.
Topics: Benzene; Environmental Exposure; Gasoline; Humans; Leukemia; Vehicle Emissions | 2017 |
Steinmaus and Smith Respond to "Proximity to Gasoline Stations and Childhood Leukemia".
Topics: Air Pollutants; Benzene; Gasoline; Housing; Humans; Leukemia | 2017 |
[Practice of recognizing benzene-caused occupational diseases in 2006].
Topics: Adult; Aged; Benzene; Female; Germany; Humans; Leukemia; Lymphoma; Male; Middle Aged; Myelodysplasti | 2008 |
Effect of urethane, X-rays, potassium arsenite, benzol, on survival time in transplanted mouse leukemia.
Topics: Animals; Arsenicals; Arsenites; Benzene; Leukemia; Leukemia, Experimental; Potassium; Potassium Comp | 1948 |
Multistage modeling of leukemia in benzene workers: a simple approach to fitting the 2-stage clonal expansion model.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Benzene; Chemical Industry; Cohort Studies; | 2009 |
Benzene risk estimation using radiation equivalent coefficients.
Topics: Adult; Benzene; Cells, Cultured; Chromosome Aberrations; Computer Simulation; Female; Humans; Inhala | 2009 |
Acute childhood leukaemia and residence next to petrol stations and automotive repair garages: the ESCALE study (SFCE).
Topics: Acute Disease; Adolescent; Age Distribution; Air Pollutants; Benzene; Carcinogens, Environmental; Ca | 2009 |
[One case of benzene induced acute leukemia].
Topics: Acute Disease; Adult; Benzene; Female; Humans; Leukemia; Occupational Exposure | 2009 |
Risk factors for leukemia in Thailand.
Topics: Adult; Aged; Benzene; Case-Control Studies; Cell Phone; Electromagnetic Fields; Female; Humans; Leuk | 2009 |
Retrospective exposure assessment in environmental epidemiology.
Topics: Acute Disease; Benzene; Child; Environmental Exposure; Environmental Monitoring; Epidemiological Mon | 2009 |
A review of the data quality and comparability of case-control studies of low-level exposure to benzene in the petroleum industry.
Topics: Benzene; Case-Control Studies; Extraction and Processing Industry; Humans; Leukemia; Occupational Ex | 2010 |
How much does benzene contribute to the overall burden of cancer due to occupation?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzene; Carcinogens; Female; Humans; Leukemia; Male; Mi | 2010 |
Ensuring comparability of benzene exposure estimates across three nested case-control studies in the petroleum industry in support of a pooled epidemiological analysis.
Topics: Benzene; Case-Control Studies; Cohort Studies; Humans; Leukemia; Occupational Exposure; Petroleum; R | 2010 |
Exposure assessment for case-control and case-case epidemiology studies based in Shanghai China: summary of methods and results.
Topics: Anemia, Aplastic; Benzene; Case-Control Studies; China; Environmental Exposure; Humans; Leukemia; Ly | 2010 |
Implications of latency period between benzene exposure and development of leukemia--a synopsis of literature.
Topics: Benzene; Cohort Studies; Germany; Humans; Leukemia; Occupational Exposure; Risk Assessment; Time Fac | 2010 |
Methylation and expression analysis of tumor suppressor genes p15 and p16 in benzene poisoning.
Topics: Aged; Benzene; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Met | 2010 |
Flexible meta-regression to assess the shape of the benzene-leukemia exposure-response curve.
Topics: Benzene; Humans; Leukemia; Occupational Exposure; Regression Analysis | 2010 |
Proposed mode of action of benzene-induced leukemia: Interpreting available data and identifying critical data gaps for risk assessment.
Topics: Animals; Benzene; Bone Marrow Cells; Carcinogens; Cytochrome P-450 Enzyme System; Humans; Leukemia; | 2010 |
Chronic lymphomatosis in a benzolic.
Topics: Benzene; Humans; Leukemia; Leukemia, Lymphoid | 1947 |
Benzene leukemia 15 months with benzol in the blood.
Topics: Benzene; Blood; Humans; Leukemia | 1946 |
Comment on: Implications of latency period between benzene exposure and development of leukemia-a synopsis of literature.
Topics: Benzene; Carcinogens; Cohort Studies; DNA Repair; Humans; Leukemia; Occupational Diseases; Occupatio | 2010 |
A graphical tool to evaluate temporal coverage of occupational history by exposure measurements.
Topics: Australia; Benzene; Canada; Case-Control Studies; Computer Graphics; Employment; Humans; Leukemia; O | 2010 |
[Observation on therapeutic effect of double unrelated umbilical cord blood transplantation for treatment of leukemia due to chronic benzene poisoning in adults].
Topics: Adult; Benzene; Cord Blood Stem Cell Transplantation; Female; Humans; Infant, Newborn; Leukemia; Mal | 2010 |
Further observations on the effect of benzene on a strain of myeloid chloroleukemia in mice and on changes produced in the leukemic cells by the chemical.
Topics: Animals; Benzene; Leukemia; Mice; Neoplasms; Sarcoma, Myeloid | 1946 |
Global gene expression profiling of a population exposed to a range of benzene levels.
Topics: Adult; Benzene; Female; Gene Expression Profiling; Humans; Leukemia; Leukocytes, Mononuclear; Lympho | 2011 |
Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene.
Topics: Adult; Aneuploidy; Benzene; Chromosomes, Human, X; Dose-Response Relationship, Drug; Female; Humans; | 2011 |
[Cases of benzene-related leukemia reported in periodicals in China and analysis of diagnosis].
Topics: Adolescent; Adult; Benzene; China; Female; Humans; Leukemia; Male; Middle Aged; Occupational Exposur | 2010 |
[Analysis on bone marrow feature of 56 clinic cases of benzene poisoning].
Topics: Adult; Anemia; Anemia, Aplastic; Benzene; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; F | 2011 |
The impact of saturable metabolism on exposure-response relations in 2 studies of benzene-induced leukemia.
Topics: Benzene; Biomarkers; Humans; Leukemia; Occupational Diseases; Occupational Exposure; Risk Assessment | 2011 |
Differential gene expression profiles of human leukemia cell lines exposed to benzene and its metabolites.
Topics: Benzene; Benzoquinones; Biomarkers; Cluster Analysis; Environmental Pollutants; Gene Expression; Gen | 2011 |
The role of residence near hazardous waste sites containing benzene in the development of hematologic cancers in upstate New York.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzene; Black or African American; Child; Child, Presch | 2011 |
Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience.
Topics: Acute Disease; Adult; Aged; Analysis of Variance; Benzene; Cell Transformation, Neoplastic; Chromoso | 2012 |
Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population.
Topics: Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Fema | 2012 |
[Carcinogenic chemicals and risk of hematopoietic neoplasms].
Topics: Alkylating Agents; Animals; Benzene; Formaldehyde; Humans; Leukemia; Thorium Dioxide; Topoisomerase | 2012 |
A methodological frame for assessing benzene induced leukemia risk mitigation due to policy measures.
Topics: Benzene; Carcinogens; Environmental Policy; Humans; Leukemia; Risk Assessment | 2013 |
Leukemia in relation to occupational exposures to benzene and other agents: a case-control study nested in a cohort of gas and electric utility workers.
Topics: Adult; Benzene; Case-Control Studies; Cohort Studies; Electricity; Gasoline; Humans; Incidence; Leuk | 2002 |
Benzene exposure and hematopoietic mortality: A long-term epidemiologic risk assessment.
Topics: Aged; Benzene; Cohort Studies; Female; Humans; Leukemia; Life Tables; Longitudinal Studies; Male; Mi | 2002 |
Effect of follow-up time on risk estimates: a longitudinal examination of the relative risks of leukemia and multiple myeloma in a rubber hydrochloride cohort.
Topics: Benzene; Cohort Studies; Dose-Response Relationship, Drug; Humans; Leukemia; Longitudinal Studies; M | 2002 |
Assessing health risk from benzene pollution in an urban area.
Topics: Adult; Air Pollution, Indoor; Benzene; Carcinogens; Environmental Exposure; Female; Humans; Italy; L | 2002 |
Lymphohaematopoietic system cancer incidence in an urban area near a coke oven plant: an ecological investigation.
Topics: Benzene; Coke; Environmental Exposure; Female; Humans; Incidence; Industry; Italy; Leukemia; Lymphom | 2003 |
Exposure to benzene and risk of leukemia among shoe factory workers.
Topics: Benzene; Carcinogens; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Industry; It | 2003 |
Mechanisms of benzene-induced hematotoxicity and leukemogenicity: cDNA microarray analyses using mouse bone marrow tissue.
Topics: Administration, Inhalation; Animals; Apoptosis; Benzene; Bone Marrow; DNA Damage; DNA Repair; Gene E | 2003 |
Lymphohaematopoeitic cancer mortality among workers with benzene exposure.
Topics: Benzene; Cause of Death; Chemical Industry; Female; Humans; Leukemia; Lymphoma; Male; Occupational D | 2003 |
[Experimental investigations on the etiology and pathogenesis of human chronic myeloid leukemia. II. Antigenic relation of benzol eosinophilia].
Topics: Benzene; Eosinophilia; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, | 1952 |
[Treatment of chronic leukemias with benzene and its homologues; role of choline and methionine].
Topics: Benzene; Choline; Humans; Leukemia; Methionine; Toluene; Xylenes | 1953 |
[Leukemoid reaction (benzene poisoning?)].
Topics: Benzene; Humans; Leukemia; Leukemoid Reaction | 1954 |
[A case of acute leukemia in a person inhaling higher benzene homologs].
Topics: Acute Disease; Benzene; Humans; Leukemia; Poisoning | 1954 |
[Acute myelosis caused by chronic benzolism with initial aspects of aplasia and subsequent symptoms of leukemia or erythro-leukemia].
Topics: Anemia; Anemia, Aplastic; Anemia, Myelophthisic; Benzene; Disease; Humans; Leukemia; Leukemia, Myelo | 1957 |
[Acute leukemia occurring 27 years after exposure to benzene fumes].
Topics: Acute Disease; Benzene; Gases; Humans; Leukemia | 1959 |
[A fatal case of benzene leukosis].
Topics: Benzene; Humans; Leukemia; Medical Records | 1960 |
[A case of myeloid leukosis due to benzene hydrocarbons. Initial long latency; hematological observations showing phases of establishment of the leukosis].
Topics: Benzene; Humans; Hydrocarbons; Leukemia; Leukemia, Myeloid | 1961 |
[Chronic myeloid leukemia after long-term contact with benzene].
Topics: Benzene; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid | 1961 |
[Negative attempt at induction of leukemia in mice by benzene].
Topics: Animals; Benzene; Leukemia; Leukemia, Experimental; Mice | 1960 |
[A case of chronic benzene poisoning terminated by acute hemocytoblastosis].
Topics: Benzene; Humans; Leukemia; Medical Records | 1962 |
[On the leukemogenic action of benzol].
Topics: Benzene; Humans; Leukemia | 1962 |
BENZENE EXPOSURE AND APLASTIC ANEMIA FOLLOWED BY LEUKEMIA 15 YEARS LATER.
Topics: Anemia; Anemia, Aplastic; Benzene; Biopsy; Leukemia; Leukemia, Myeloid; Pathology; Toxicology | 1963 |
BENZENE LEUKEMIAS.
Topics: Benzene; Leukemia; Neoplasms; Occupational Diseases; Toxicology; USSR | 1963 |
[PRELEUKEMIC STATES].
Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Benzene; Leukemia; Leukemia, Myeloid; Leukemia, Radiati | 1963 |
[BENZENE BLOOD DISEASE. 3 CASES OF CHRONIC BENZENE POISONING OF WHICH 2 WERE FATAL (ACUTE LEUKEMIA, ACUTE PANMYELOPHTHISIS)].
Topics: Adrenocorticotropic Hormone; Anemia; Anemia, Myelophthisic; Anti-Bacterial Agents; Ascorbic Acid; Be | 1963 |
[CLINICAL CONTRIBUTION TO THE STUDY OF BLOOD DISEASES INDUCED BY BENZENE HYDROCARBONS AND PROBLEMS OF PREVENTION].
Topics: Adolescent; Anemia; Asthenia; Benzene; Bone Marrow Examination; Cerebral Hemorrhage; Hematologic Dis | 1963 |
[LEUKEMOID STATES AND INITIAL STAGES OF LEUKEMIA].
Topics: Anemia; Benzene; Bone Marrow Diseases; Hemolysis; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-I | 1964 |
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Coba | 1964 |
[ASSESSMENT OF OCCUPATIONAL LEUKEMIA IN SUBJECTS EXPOSED TO BENZENE].
Topics: Benzene; Genetic Diseases, X-Linked; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid; Lymphatic Di | 1964 |
[ON HYPOPLASTIC STATES IN HEMATOPOIESIS AS A PRECURSOR OF ACUTE LEUKOSIS].
Topics: Benzene; Bone Marrow Diseases; Hematopoiesis; Leukemia; Leukopenia; Radiation Injuries; Toxicology | 1964 |
BENZENE AND LEUKEMIA.
Topics: Anemia; Anemia, Aplastic; Benzene; Leukemia; Leukemoid Reaction; Leukopenia; Occupational Diseases; | 1964 |
REFRACTORY SIDEROBLASTIC ANEMIA. CLINICAL AND HEMATOLOGIC STUDY OF TEN CASES.
Topics: Anemia; Anemia, Sideroblastic; Benzene; Bone Marrow; Carbon Tetrachloride; Geriatrics; Hematology; H | 1964 |
CHROMOSOME ABERRATIONS AND EXPOSURE TO AMBIENT BENZENE.
Topics: Benzene; Chromosome Aberrations; Humans; Leukemia; Lymphocytes; Neoplasms; Occupational Diseases; Ra | 1965 |
[BENZENE, BENZENE HOMOLOGUES AND MYELOID LEUKEMIA].
Topics: Benzene; Carcinogens; Germany; Germany, West; Leukemia; Leukemia, Myeloid; Toxicology | 1964 |
[A CASE OF MYELOGENOUS LEUKEMIA SUSPECTED TO HAVE BEEN CAUSED BY BENZOL POISONING].
Topics: Anemia; Anemia, Aplastic; Benzene; Leukemia; Leukemia, Myeloid; Poisoning; Toxicology | 1965 |
Leukemia risk associated with low-level benzene exposure.
Topics: Adult; Aged; Benzene; Case-Control Studies; Cohort Studies; Humans; Leukemia; Male; Middle Aged; Occ | 2003 |
A note on myeloperoxidation index and its correlation to the biomarker, urine trans, trans-muconic acid level, in the subjects occupationally exposed to benzene.
Topics: Benzene; Biomarkers; Hematologic Tests; Humans; Leukemia; Male; Occupational Exposure; Peroxidase; S | 2004 |
[Study on the relationship between glutathione S transferase mu gene deletion and leukemia in workers exposed to benzene].
Topics: Benzene; Case-Control Studies; Gene Deletion; Glutathione Transferase; Humans; Leukemia; Logistic Mo | 2002 |
Childhood leukemia and road traffic: A population-based case-control study.
Topics: Adolescent; Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Female; Humans; | 2004 |
Leukemia risk and relevant benzene exposure period-Re: follow-up time on risk estimates, Am J Ind Med 42:481-489, 2002.
Topics: Australia; Benzene; Case-Control Studies; Humans; Leukemia; Multiple Myeloma; Occupational Diseases; | 2004 |
Lymphohaematopoietic cancer risk among chemical workers exposed to benzene.
Topics: Adult; Aged; Benzene; Chemical Industry; Cohort Studies; Female; Follow-Up Studies; Humans; Leukemia | 2004 |
Agreement of job-exposure matrix (JEM) assessed exposure and self-reported exposure among adult leukemia patients and controls in Shanghai.
Topics: Adult; Aged; Benzene; Case-Control Studies; China; Data Collection; Electromagnetic Fields; Female; | 2004 |
Story of benzene and leukemia: epidemiologic approach of Muzaffer Aksoy.
Topics: Benzene; History, 20th Century; Humans; Leukemia; Occupational Exposure; Risk Factors; Turkey | 2004 |
Benzene exposure and leukemia.
Topics: Benzene; Bias; Humans; Leukemia; Occupational Exposure; Petroleum; Risk Assessment; Sentinel Surveil | 2004 |
Benzene exposure and leukemia.
Topics: Benzene; Bias; Humans; Leukemia; Occupational Exposure; Petroleum; Risk Assessment | 2004 |
Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.
Topics: Animals; Apoptosis; Benzene; Benzoquinones; Carcinogens; Cell Cycle Proteins; Cell Transformation, N | 2004 |
Erythroleukaemic myelosis in benzene poisoning.
Topics: Benzene; Humans; Industry; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Occupational | 1950 |
Leukemia risk in caprolactam workers exposed to benzene.
Topics: Algorithms; Benzene; Caprolactam; Cause of Death; Chemical Industry; Cohort Studies; Humans; Leukemi | 2005 |
Cancer risks in a historical UK cohort of benzene exposed workers.
Topics: Benzene; Carcinogens, Environmental; Cause of Death; Cohort Studies; England; Female; Humans; Incide | 2005 |
Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase II alpha: 1,4-hydroquinone is a topoisomerase II poison.
Topics: Antigens, Neoplasm; Benzene; Cells, Cultured; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins | 2005 |
International symposium: Recent advances in benzene toxicity.
Topics: Air Pollutants, Occupational; Benzene; Biomarkers; Humans; Leukemia; Occupational Diseases; Occupati | 2005 |
Health Watch exposure estimates: do they underestimate benzene exposure?
Topics: Air Pollutants, Occupational; Australia; Benzene; Case-Control Studies; Employment; Humans; Leukemia | 2005 |
Surviving apoptosis: a possible mechanism of benzene-induced leukemia.
Topics: Animals; Apoptosis; Benzene; DNA Damage; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; H | 2005 |
Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene.
Topics: Benzene; Benzoquinones; Carcinogens; Dithiothreitol; DNA Topoisomerases, Type II; DNA, Kinetoplast; | 2005 |
Benzene metabolites block gap junction intercellular communication. Role in hematotoxicity and leukemia?
Topics: Aldehydes; Animals; Benzene; Cell Communication; Cell Line; Gap Junctions; Hematologic Diseases; Hyd | 2005 |
Lifestyle factors and the risk of adult leukemia in Canada.
Topics: Age Distribution; Benzene; Body Mass Index; Canada; Case-Control Studies; Diet; Female; Fruit; Human | 2005 |
Comment on Caprolactam study.
Topics: Benzene; Caprolactam; Chemical Industry; Cohort Studies; Humans; Leukemia; Netherlands; Occupational | 2005 |
Risk of cancer as a result of community exposure to gasoline vapors.
Topics: Adolescent; Adult; Aged; Benzene; Carcinogens, Environmental; Cohort Studies; Environmental Exposure | 2004 |
Physiologically-based pharmacokinetic modeling of benzene in humans: a Bayesian approach.
Topics: Analysis of Variance; Bayes Theorem; Benzene; Environmental Pollutants; Humans; Leukemia; Markov Cha | 2006 |
The health watch case-control study of leukemia and benzene: the story so far.
Topics: Benzene; Case-Control Studies; Cohort Studies; Humans; Leukemia; Male; Occupational Exposure; Retros | 2006 |
Progress of epidemiological and molecular epidemiological studies on benzene in China.
Topics: Benzene; Cell Transformation, Neoplastic; China; Cohort Studies; Dose-Response Relationship, Drug; H | 2006 |
Commentary on "Penetration of benzene, toluene and xylenes contained in gasolines through human abdominal skin in vitro".
Topics: Benzene; Carcinogens; Humans; Leukemia; Occupational Exposure; Permeability; Risk Assessment; Skin A | 2008 |
Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers.
Topics: Adult; Benzene; Case-Control Studies; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Huma | 2007 |
Incidence of lymphohaematopoietic cancer at a university laboratory: a cluster investigation.
Topics: Adult; Benzene; Chemistry, Organic; Cluster Analysis; Cohort Studies; Female; Hodgkin Disease; Human | 2008 |
Benzolism and acute leukemia.
Topics: Benzene; Humans; Leukemia | 1949 |
Temporal variation in the association between benzene and leukemia mortality.
Topics: Adult; Age Factors; Benzene; Carcinogens, Environmental; Chemical Industry; Cohort Studies; Female; | 2008 |
[Case of acute leukemia complicated by pulmonary aspergillosis in its terminal stage presenting aplastic anemia-like symptoms at autopsy].
Topics: Anemia, Aplastic; Aspergillosis; Benzene; Cerebral Hemorrhage; Diagnosis, Differential; Humans; Leuk | 1966 |
A critical look at hazards from benzene in workplace and community air.
Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Denmark; Gasoline; Humans; Leukemia; Netherla | 1982 |
Benzene: a multipotential carcinogen. Results of long-term bioassays performed at the Bologna Institute of Oncology.
Topics: Animals; Benzene; Bone Marrow; Cricetinae; Drug Evaluation, Preclinical; Female; History, 20th Centu | 1983 |
The benzene problem in historical perspective.
Topics: Agranulocytosis; Animals; Benzene; Bone Marrow; Humans; Immunosuppressive Agents; Leukemia; Maximum | 1984 |
An overview of environmental and toxicological aspects of aromatic hydrocarbons. I. Benzene.
Topics: Animals; Benzene; Bone Marrow; Environmental Exposure; Environmental Health; Environmental Pollutant | 1984 |
An hypothesis for the induction of leukemia by benzene.
Topics: Benzene; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Occupational D | 1983 |
[Effect of organic solvents containing benzene and its homologues on the hematopoietic system].
Topics: Animals; Benzene; Blood Cell Count; Blood Cells; Blood Coagulation; Female; Hematopoietic System; Hu | 1983 |
Leukemia and benzene.
Topics: Benzene; Humans; Leukemia; Maximum Allowable Concentration; Occupational Diseases; Risk | 1983 |
Benzene: epidemiologic observations of leukemia by cell type and adverse health effects associated with low-level exposure.
Topics: Adult; Aged; Benzene; Chromosome Aberrations; Dose-Response Relationship, Drug; Humans; Legislation | 1983 |
An evaluation of the associations of leukemia and rubber industry solvent exposures.
Topics: Adult; Benzene; Female; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Rubber; Solvents | 1984 |
Association of childhood leukemia with maternal age, birth order, and paternal occupation. A case-control study.
Topics: Adolescent; Adult; Benzene; Birth Order; California; Child; Fathers; Female; Humans; Leukemia; Male; | 1984 |
Malignancies due to occupational exposure to benzene.
Topics: Benzene; Humans; Leukemia; Lung Neoplasms; Lymphoma; Multiple Myeloma; Neoplasms; Occupational Disea | 1980 |
The benefits and costs of regulating benzene.
Topics: Air Pollutants; Benzene; Cost-Benefit Analysis; Government Agencies; Humans; Leukemia; United States | 1981 |
Mortality among chemical workers exposed to benzene and other agents.
Topics: Adult; Aged; Benzene; Chemical Industry; Humans; Leukemia; Male; Middle Aged; Multiple Myeloma; Neop | 1983 |
Benzene, leukemia, and the Supreme Court.
Topics: Benzene; Government Agencies; Health Policy; Humans; Jurisprudence; Leukemia; Maximum Allowable Conc | 1981 |
[Risk factor benzene (author's transl)].
Topics: Anemia, Aplastic; Benzene; Hematologic Diseases; Hematopoiesis; Humans; Leukemia; Occupational Disea | 1981 |
Leukemia in benzene workers.
Topics: Adult; Aged; Air Pollutants; Air Pollutants, Occupational; Benzene; Epidemiologic Methods; Humans; L | 1981 |
A case-control study of occupational exposures and leukaemia.
Topics: Agriculture; Benzene; Epidemiologic Methods; Female; Health Occupations; Humans; Leukemia; Male; Mid | 1980 |
A mortality survey of employees engaged in the development or manufacture of styrene-based products.
Topics: Benzene; Chemical Industry; Coloring Agents; Humans; Leukemia; Male; Neoplasms; Occupational Disease | 1980 |
Does nutritional status affect benzene induced toxicity and/or leukemia?
Topics: Animals; Ascorbic Acid; Benzene; Dietary Fats; Dietary Proteins; Dogs; Energy Metabolism; Humans; Ir | 1980 |
Benzene in the workplace.
Topics: Air Pollutants; Anemia, Aplastic; Benzene; Humans; Leukemia; Maximum Allowable Concentration; Occupa | 1980 |
A case-control study to investigate the association between exposure to benzene and deaths from leukaemia in oil refinery workers.
Topics: Benzene; Chemical Industry; Humans; Leukemia; Models, Biological; Occupational Diseases; Petroleum; | 1981 |
Haematopoietic cancer mortality among vehicle mechanics.
Topics: Adult; Benzene; Cause of Death; District of Columbia; Gasoline; Humans; Leukemia; Lymphoma; Male; Mi | 1995 |
Benzene exposure assessment in rubber hydrochloride workers: a critical evaluation of previous estimates.
Topics: Air Pollutants, Occupational; Benzene; Cohort Studies; Humans; Leukemia; Occupational Diseases; Occu | 1995 |
Apparent association between benzene and childhood leukaemia: methodological doubts concerning a report by Knox.
Topics: Benzene; Case-Control Studies; Child; Child, Preschool; Cluster Analysis; Data Interpretation, Stati | 1995 |
Gasoline consumption and leukemia mortality and morbidity in 19 European countries: an ecological study.
Topics: Adult; Air Pollutants; Benzene; Dose-Response Relationship, Drug; Europe; Female; Gasoline; Humans; | 1995 |
A screen for RAS mutations in individuals at risk of secondary leukaemia due to occupational exposure to petrochemicals.
Topics: Adult; Benzene; Genes, ras; Humans; Leukemia; Mutation; Occupational Diseases; Oligonucleotide Probe | 1995 |
Gender differences in hematopoietic and lymphoproliferative disorders and other cancer risks by major occupational group among workers exposed to benzene in China.
Topics: Benzene; China; Cohort Studies; Female; Hematologic Diseases; Hematopoietic System; Humans; Leukemia | 1994 |
Leukemia risk associated with benzene exposure in the pliofilm cohort: I. Mortality update and exposure distribution.
Topics: Adult; Aged; Benzene; Chemical Industry; Cohort Studies; Dose-Response Relationship, Drug; Female; H | 1994 |
Leukemia risk associated with benzene exposure in the pliofilm cohort. II. Risk estimates.
Topics: Aged; Benzene; Chemical Industry; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; | 1994 |
Rings of controversy around benzene.
Topics: Benzene; Bone Marrow; Carcinogens; China; Environmental Exposure; Europe; Humans; Leukemia; Risk Fac | 1994 |
Risk of benzene-induced leukemia: a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates.
Topics: Adult; Aged; Benzene; Cohort Studies; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; L | 1994 |
A cohort study of cancer among benzene-exposed workers in China: overall results.
Topics: Adult; Age Distribution; Benzene; China; Cohort Studies; Confidence Intervals; Female; Humans; Incid | 1996 |
Retrospective benzene and total hydrocarbon exposure assessment for a petroleum marketing and distribution worker epidemiology study.
Topics: Algorithms; Benzene; Canada; Environmental Monitoring; Epidemiological Monitoring; Humans; Hydrocarb | 1996 |
Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry.
Topics: Benzene; Butadienes; Carcinogens; Humans; Leukemia; Male; Occupational Diseases; Occupational Exposu | 1996 |
Determination of leukemogenic benzene exposure concentrations: refined analyses of the Pliofilm cohort.
Topics: Benzene; Carcinogens; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Le | 1996 |
Lymphohaematopoietic malignancies and quantitative estimates of exposure to benzene in Canadian petroleum distribution workers.
Topics: Aged; Benzene; Canada; Case-Control Studies; Cause of Death; Histiocytic Disorders, Malignant; Human | 1996 |
Cancer mortality among workers with benzene exposure.
Topics: Benzene; Cause of Death; Chemical Industry; Cohort Studies; Confidence Intervals; Humans; Illinois; | 1997 |
An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group.
Topics: Anemia, Aplastic; Benzene; Carcinogens; China; Cohort Studies; Female; Humans; Leukemia; Leukemia, M | 1996 |
Mortality among benzene-exposed workers in China.
Topics: Benzene; China; Cohort Studies; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Neoplasms; | 1996 |
Benzene exposure in the petroleum distribution industry associated with leukemia in the United Kingdom: overview of the methodology of a case-control study.
Topics: Benzene; Case-Control Studies; Cohort Studies; Epidemiologic Methods; Humans; Leukemia; Occupational | 1996 |
The relationship between low-level benzene exposure and leukemia in Canadian petroleum distribution workers.
Topics: Adult; Aged; Benzene; Carcinogens; Case-Control Studies; Cohort Studies; Humans; Leukemia; Logistic | 1996 |
Leukemia risk associated with benzene exposure in the Pliofilm cohort.
Topics: Benzene; Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukem | 1996 |
Risk of benzene-induced leukemia predicted from the Pliofilm cohort.
Topics: Benzene; Cohort Studies; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Leukemia; Leuk | 1996 |
A case-control study to investigate the risk of leukaemia associated with exposure to benzene in petroleum marketing and distribution workers in the United Kingdom.
Topics: Benzene; Case-Control Studies; Cohort Studies; Death Certificates; Humans; Leukemia; Leukemia, Lymph | 1997 |
Retrospective estimation of exposure to benzene in a leukaemia case-control study of petroleum marketing and distribution workers in the United Kingdom.
Topics: Benzene; Case-Control Studies; Cohort Studies; Environmental Monitoring; Epidemiological Monitoring; | 1997 |
Report on the workshop entitled: "Modeling chemically induced leukemia--implications for benzene risk assessment".
Topics: Animals; Benzene; Biotransformation; Carcinogens; Hematopoietic Stem Cells; Humans; Leukemia; Leukem | 1997 |
Environmental exposure to gasoline and leukemia in children and young adults--an ecology study.
Topics: Adolescent; Adult; Automobiles; Benzene; Child; Child, Preschool; Environmental Exposure; Female; Ga | 1997 |
Scientific update on benzene.
Topics: Anemia, Aplastic; Benzene; Biotransformation; Bone Marrow; Humans; Leukemia; Liver | 1997 |
Biomarkers of leukemia risk: benzene as a model.
Topics: Adult; Benzene; Biomarkers; Child; Chromosome Aberrations; Environmental Exposure; Genetic Predispos | 1998 |
Leukaemia, lymphoma, and multiple myeloma in seamen on tankers.
Topics: Adult; Benzene; Case-Control Studies; Humans; Leukemia; Lymphoma; Male; Medical Record Linkage; Midd | 1998 |
Investigation of a cluster of leukaemia in the Illawarra region of New South Wales, 1989-1996.
Topics: Adolescent; Adult; Air Pollution; Benzene; Cluster Analysis; Confounding Factors, Epidemiologic; Env | 1999 |
A critique of the exposure assessment in the epidemiologic study of benzene-exposed workers in China conducted by the Chinese Academy of Preventive Medicine and the US National Cancer Institute.
Topics: Benzene; China; Dose-Response Relationship, Drug; Humans; Leukemia; Occupational Diseases; Occupatio | 1999 |
Analysis of incidence of childhood cancer in the West Midlands of the United Kingdom in relation to proximity to main roads and petrol stations.
Topics: Adolescent; Air Pollutants; Benzene; Carcinogens, Environmental; Child; Child, Preschool; England; F | 1999 |
The contribution of benzene to smoking-induced leukemia.
Topics: Adolescent; Adult; Aged; Animals; Benzene; Child; Child, Preschool; Cohort Studies; Dogs; Female; Hu | 2000 |
Retrospective exposure assessment for benzene in the Australian petroleum industry.
Topics: Australia; Benzene; Case-Control Studies; Humans; Leukemia; Models, Theoretical; Occupational Exposu | 2000 |
Leukemia after exposure to benzene: temporal trends and implications for standards.
Topics: Adult; Benzene; Case-Control Studies; Confidence Intervals; Environmental Monitoring; Epidemiologica | 2000 |
Childhood cancer and possible exposure to benzene from traffic and petrol stations.
Topics: Benzene; Child; Child, Preschool; Environmental Exposure; Humans; Leukemia; Vehicle Emissions | 2000 |
Petroleum worker studies and benzene risk assessment.
Topics: Benzene; Carcinogens; Case-Control Studies; Extraction and Processing Industry; Humans; Leukemia; Ly | 2000 |
Issues for discussion: benzene-induced leukemia--human studies.
Topics: Benzene; Biomarkers, Tumor; China; Epidemiology; Extraction and Processing Industry; Humans; Leukemi | 2000 |
Carcinogenic effects of benzene--a status update and research needs to improve risk assessments: US EPA perspective. Environmental Protection Agency.
Topics: Benzene; Carcinogens; Dose-Response Relationship, Drug; Humans; Leukemia; Likelihood Functions; Line | 2000 |
Benzene status of assessment--priority substances program.
Topics: Benzene; Canada; Carcinogens; Dose-Response Relationship, Drug; Environment; Humans; Leukemia; Publi | 2000 |
From cyclophosphamide hematotoxicity to modeling cancer.
Topics: Animals; Benzene; Carcinogens; Cyclophosphamide; Dose-Response Relationship, Drug; Hematologic Disea | 2000 |
Review of the Cox model.
Topics: Animals; Benzene; Cyclophosphamide; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Huma | 2000 |
Biologically based risk assessment model for cyclophosphamide hematotoxicity in animal species: concluding comments.
Topics: Animals; Benzene; Cyclophosphamide; Dogs; Hematologic Diseases; Hematopoietic Stem Cells; Humans; Le | 2000 |
The influence of occupation on health--some results from a study in the UK oil industry.
Topics: Benzene; Cause of Death; Chemical Industry; Epidemiologic Methods; Humans; Leukemia; Male; Neoplasms | 1980 |
Air pollution from traffic at the residence of children with cancer.
Topics: Adolescent; Adult; Air Pollutants; Benzene; Brain Neoplasms; Case-Control Studies; Child; Child, Pre | 2001 |
Estimating mean exposures from censored data: exposure to benzene in the Australian petroleum industry.
Topics: Australia; Benzene; Epidemiologic Methods; Humans; Leukemia; Likelihood Functions; Lymphoproliferati | 2001 |
Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Benzene; Carcinogens; DNA; DNA Topoisomerases | 2001 |
Re: Benzene and lymphohematopoietic malignancies in humans. Hayes et al. Am. J. Ind. Med. 40:117-126, 2001.
Topics: Benzene; Hematologic Neoplasms; Humans; Incidence; Leukemia; Lymphoma; Occupational Exposure; Occupa | 2001 |
Leukemia mortality and occupational exposure to rubber: a nested case-control study.
Topics: Adult; Aged; Benzene; Case-Control Studies; Female; Humans; Industry; Leukemia; Male; Middle Aged; O | 2002 |
[Traffic-related air pollution at the place of residence and risk of cancer among children].
Topics: Adolescent; Air Pollutants; Benzene; Central Nervous System Neoplasms; Child; Child, Preschool; Denm | 2002 |
Leukaemia in benzene workers.
Topics: Adult; Aged; Benzene; Chemical Industry; Follow-Up Studies; Humans; Leukemia; Leukemia, Myeloid; Leu | 1977 |
Benzene and leukaemia.
Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Chemical Industry; Humans; Leukemia; Leukemia | 1977 |
Non-industrial exposure to benzene as leukaemogenic risk factor.
Topics: Acute Disease; Adolescent; Adult; Benzene; Environmental Exposure; Female; Humans; Leukemia; Leukemi | 1977 |
Benzene and leukemia.
Topics: Benzene; Environmental Exposure; Humans; Leukemia; Occupational Diseases; Shoes; Turkey | 1978 |
[Hematological damage of occupational origin in industry].
Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Benzene Derivatives; Environmental Pollutants | 1978 |
Experimental benzene intoxication.
Topics: Administration, Oral; Animals; Benzene; Embryo, Mammalian; Embryo, Nonmammalian; Female; Hematopoies | 1977 |
Chromosome analysis in two unusual malignant blood disorders presumably induced by benzene.
Topics: Adult; Aged; Benzene; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Hemat | 1979 |
[Benzene-origin leukemias].
Topics: Benzene; Benzene Derivatives; Humans; Leukemia | 1979 |
[Leukemia in benzene workers (report of 3 cases) (author's transl)].
Topics: Adult; Benzene; Female; Humans; Leukemia; Male; Middle Aged; Occupational Diseases | 1979 |
Bone marrow depressant and leukemogenic actions of benzene.
Topics: Animals; Benzene; Bone Marrow; Cell Division; Erythrocytes; Humans; Leukemia; Liver; Reticulocytes | 1977 |
Leukemia in workers due to occupational exposure to benzene.
Topics: Adolescent; Adult; Aged; Benzene; Environmental Exposure; Humans; Leukemia; Middle Aged; Occupationa | 1977 |
International workshop on toxicology of benzene, Paris: 9th - 11th November 1976.
Topics: Animals; Benzene; Bone Marrow Diseases; Chromosome Aberrations; Environmental Exposure; Humans; Leuk | 1978 |
Occupational exposure to petroleum products in men with acute non-lymphocytic leukaemia.
Topics: Adult; Aged; Benzene; Environmental Exposure; Humans; Leukemia; Male; Middle Aged; Occupational Dise | 1978 |
Followup study on the mortality and the development of leukemia in 44 pancytopenic patients with chronic exposure to benzene.
Topics: Adolescent; Adult; Benzene; Bone Marrow; Environmental Exposure; Female; Fetal Hemoglobin; Follow-Up | 1978 |
Mortality experience of styrene-polystyrene polymerization workers. Initial findings.
Topics: Adult; Aged; Benzene; Cardiovascular Diseases; Environmental Exposure; Follow-Up Studies; Humans; Le | 1978 |
Leukemia among workers exposed to benzene.
Topics: Benzene; Carcinogens, Environmental; Environmental Exposure; Household Products; Humans; Leukemia; M | 1978 |
Protection from adverse effects of benzene.
Topics: Animals; Benzene; Carcinogens, Environmental; Government Agencies; Humans; Leukemia; Leukemia, Exper | 1978 |
Benzene: cancer risk demands cancer control.
Topics: Benzene; Carcinogens, Environmental; Chemical Industry; Government Agencies; Humans; Labor Unions; L | 1978 |
Comments on session VI: benzene and health effects.
Topics: Benzene; Carcinogens, Environmental; Government Agencies; Humans; Leukemia; Maximum Allowable Concen | 1978 |
Types of leukemia in chronic benzene poisoning. A study in thirty-four patients.
Topics: Adolescent; Adult; Benzene; Environmental Exposure; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, | 1976 |
[Current views on the origin of human leukemia].
Topics: Benzene; Humans; Leukemia; Leukemia, Radiation-Induced; Oncogenic Viruses; Radiation, Ionizing | 1977 |
Combination of genetic factors and chronic exposure to benzene in the aetiology of leukaemia.
Topics: Acute Disease; Adult; Aged; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Leukemi | 1976 |
[Benzene acute aleukemic leukosis, with widespread leukemic parenchymal infiltration (author's transl)].
Topics: Autopsy; Benzene; Humans; Leukemia; Male; Occupational Diseases | 1976 |
Solvent exposure and leukemia among rubber workers: an epidemiologic study.
Topics: Adult; Age Factors; Benzene; Environmental Exposure; Epidemiologic Methods; Female; Humans; Leukemia | 1975 |
Leukemia associated with benzene exposure.
Topics: Acute Disease; Adult; Aged; Air Pollutants, Occupational; Anemia; Anemia, Aplastic; Benzene; Carcino | 1976 |
Letters to the editor: Leukemia and potential benzene exposure.
Topics: Benzene; Environmental Exposure; Humans; Leukemia; Occupational Diseases; Petroleum; Retrospective S | 1975 |
Haematological problems at work.
Topics: Anemia, Aplastic; Benzene; Carbon Monoxide Poisoning; Carboxyhemoglobin; Glucosephosphate Dehydrogen | 1976 |
Correlation between car ownership and leukaemia: is non-occupational exposure to benzene from petrol and motor vehicle exhaust a causative factor in leukaemia and lymphoma?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzene; Child; Child, Preschool; Environmental Exposure | 1992 |
[Secondary leukemia and the countermeasures].
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzene; Down Syndrome; Hematologic Diseases; Hodgki | 1992 |
Ethionine: a new antileukaemic drug?
Topics: Antineoplastic Agents; Benzene; Drug Synergism; Drug Therapy, Combination; Ethionine; Humans; Leukem | 1992 |
Biomarkers in occupational cancer epidemiology: considerations in study design.
Topics: Benzene; Benzidines; Biomarkers, Tumor; Case-Control Studies; Cohort Studies; Disease Susceptibility | 1992 |
[Exposure to gasoline and leukemia: a small risk for many].
Topics: Benzene; Female; Gasoline; Humans; Leukemia; Male; Occupational Exposure; Risk Factors | 1992 |
Exposure to benzene and mortality from leukaemia: results from coke oven and other coal product workers.
Topics: Aged; Benzene; Coal; Cohort Studies; Coke; Humans; Leukemia; Male; Middle Aged; Occupational Disease | 1991 |
Benzene in petrol: a continuing hazard.
Topics: Adult; Benzene; Gasoline; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Petroleum; Sol | 1990 |
Chemical carcinogenesis.
Topics: Animals; Benzene; Humans; Leukemia; Lymphoma; Time Factors; Toluene | 1991 |
Parental occupations of children with leukaemia in west Cumbria, north Humberside, and Gateshead.
Topics: Adolescent; Benzene; Case-Control Studies; Child; Child, Preschool; England; Female; Humans; Infant; | 1991 |
Benzene and leukemia.
Topics: Benzene; Humans; Leukemia; Occupational Diseases; Risk Factors | 1991 |
Other factors in leukemia.
Topics: Benzene; Humans; Leukemia; Occupational Diseases; Reproducibility of Results; Risk Factors | 1991 |
The real role of risk assessment in cancer risk management.
Topics: Benzene; Humans; Leukemia; Neoplasms | 1991 |
Risk assessment of leukaemia and occupational exposure to benzene.
Topics: Benzene; Humans; Leukemia; Occupational Diseases; Risk | 1990 |
The exposure of the general population to benzene.
Topics: Air Pollutants, Occupational; Benzene; Half-Life; Humans; Leukemia; Occupational Diseases; Risk; Smo | 1989 |
Re: "Benzene and Leukemia: a Review of the Literature and a Risk Assessment".
Topics: Benzene; Cohort Studies; Humans; Leukemia; Retrospective Studies; Risk Factors | 1989 |
Quantitative assessment of lives lost due to delay in the regulation of occupational exposure to benzene.
Topics: Benzene; Epidemiologic Methods; Humans; Leukemia; Maximum Allowable Concentration; Occupational Dise | 1989 |
Benzene and leukemia: an epidemiologic risk assessment.
Topics: Benzene; Cohort Studies; Humans; Leukemia; Male; Mathematics; National Institute for Occupational Sa | 1989 |
A retrospective cohort study of leukemia and other cancers in benzene workers.
Topics: Adolescent; Adult; Aged; Benzene; China; Cohort Studies; Female; Humans; Leukemia; Male; Middle Aged | 1989 |
Aplastic anemia, leukemia and other cancer mortality in a cohort of shoe workers exposed to benzene.
Topics: Adhesives; Anemia, Aplastic; Benzene; Female; Humans; Italy; Leukemia; Male; Neoplasms; Occupational | 1989 |
Occupational benzene exposure: preventable deaths.
Topics: Benzene; Humans; Leukemia; Occupational Diseases | 1988 |
Recent laboratory studies in chemical carcinogenesis: benzene.
Topics: Benzene; Humans; Leukemia; Occupational Diseases; Risk Factors; Skin Absorption | 1988 |
[What is good for the car is not safe for the human. Damage to health by benzol--leukemia following chronic exposure--challenges].
Topics: Air Pollutants; Benzene; Humans; Leukemia; Risk Factors | 1988 |
Cigarette smoking and leukemia.
Topics: Acute Disease; Benzene; Chronic Disease; Epidemiologic Methods; Female; Follow-Up Studies; Humans; L | 1986 |
A case-control study of leukemia at an oil refinery.
Topics: Benzene; Follow-Up Studies; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Occupational Diseases; | 1986 |
Benzene and leukemia. An epidemiologic risk assessment.
Topics: Adult; Aged; Benzene; Environmental Exposure; Humans; Industry; Leukemia; Male; Middle Aged; Occupat | 1987 |
Benzene: evaluation of control measures not competitive with basic research requirements.
Topics: Benzene; Humans; Leukemia; Occupational Diseases; Public Policy; Risk; United States | 1987 |
Benzene and leukemia.
Topics: Benzene; Humans; Leukemia; Occupational Diseases | 1987 |
An industry wide mortality study of chemical workers occupationally exposed to benzene. I. General results.
Topics: Adult; Age Factors; Aged; Benzene; Chemical Industry; Humans; Kidney Neoplasms; Leukemia; Lymphoma, | 1987 |
An industry wide mortality study of chemical workers occupationally exposed to benzene. II. Dose response analyses.
Topics: Adult; Age Factors; Aged; Benzene; Chemical Industry; Dose-Response Relationship, Drug; Humans; Leuk | 1987 |
Benzene and leukemia.
Topics: Benzene; Environmental Exposure; Humans; Leukemia; Occupational Diseases; United States | 1987 |
Time-related factors in quantitative risk assessment.
Topics: Actuarial Analysis; Age Factors; Asbestos; Benzene; Humans; Leukemia; Mesothelioma; Models, Biologic | 1987 |
Exposure to benzene in Turkey between 1983 and 1985: a haematological study on 231 workers.
Topics: Adolescent; Adult; Air Pollutants, Occupational; Benzene; Hematologic Diseases; Hematologic Tests; H | 1987 |
Leukaemia in benzene workers: a retrospective cohort study.
Topics: Adult; Benzene; China; Female; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Retrospec | 1987 |
Occupational exposure to benzene in China.
Topics: Adult; Anemia, Aplastic; Benzene; China; Female; Humans; Leukemia; Male; Maximum Allowable Concentra | 1987 |
Malignancies due to occupational exposure to benzene.
Topics: Adult; Benzene; Cholera Vaccines; Humans; Leukemia; Lung Neoplasms; Lymphoma; Middle Aged; Multiple | 1985 |
Benzene as a leukemogenic and carcinogenic agent.
Topics: Benzene; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Multiple Myeloma; Occupational | 1985 |
Cancer risk and viral transformation.
Topics: Benzene; Carcinogens; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; | 1969 |
Persons with exceptionally high risk of leukemia.
Topics: Adult; Aneuploidy; Benzene; Child; Child, Preschool; Chromosome Aberrations; Diseases in Twins; Down | 1967 |
[Benzene leukemia].
Topics: Benzene; Environmental Exposure; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Occupat | 1969 |
[Comments on indemnifiction for benzene-induced leukemia and aplasia (apropos of 48 cases)].
Topics: Anemia, Aplastic; Benzene; France; Humans; Leukemia; Workers' Compensation | 1971 |
Chromosome aberrations--red herring or red flag?
Topics: Alkylating Agents; Anemia, Aplastic; Ataxia Telangiectasia; Benzene; Chromosome Aberrations; Down Sy | 1973 |
[Studies on the composition and carcinogenic properties of substances contained in dust suspended in atmospheric air. II. Studies on carcinogenic properties of benzene extracts from the atmospheric dust collected in 10 towns in Poland].
Topics: Adenocarcinoma; Air Pollution; Animals; Benzene; Breast Neoplasms; Carcinogens; Carcinoma, Hepatocel | 1970 |
Problems in leukemia etiology.
Topics: Animals; Benzene; Diseases in Twins; Down Syndrome; Fanconi Syndrome; Humans; Leukemia; Leukemia Vir | 1970 |
[Leukosis induced by benzene (author's transl)].
Topics: Anemia, Aplastic; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Leukemia; Occupat | 1974 |
Radiation and drug therapies, and leukemia.
Topics: Antineoplastic Agents; Benzene; Bone Marrow Diseases; Chloramphenicol; Cyclophosphamide; Dose-Respon | 1973 |
Cytogenetic studies in thirteen patients with pancytopenia and leukaemia associated with long-term exposure to benzene.
Topics: Adult; Anemia, Aplastic; Benzene; Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Human, 6-1 | 1973 |
Leukemia in shoe-workers exposed chronically to benzene.
Topics: Adult; Benzene; Bone Marrow Examination; Cell Nucleus; Erythropoiesis; Humans; Leukemia; Leukemia, E | 1974 |
Multiple cistrons for fetal hemoglobin in man.
Topics: Adult; Alleles; Amino Acid Sequence; Amino Acids; Anemia; Benzene; Child, Preschool; Fanconi Syndrom | 1974 |
[Cytogenetic studies following chronic exposure to benzene (author's transl)].
Topics: Adult; Benzene; Blood Cells; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Chromosome Abe | 1973 |
[Leukemia origin after benzene and phenylbutazone].
Topics: Adult; Benzene; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Phenylbutazone | 1973 |
Preleukemic states.
Topics: Abnormalities, Multiple; Adolescent; Adult; Aged; Agranulocytosis; Anemia, Aplastic; Ataxia Telangie | 1974 |
Epidemiologic survey of leukemia in persons potentially exposed to benzene.
Topics: Benzene; Environmental Exposure; Europe; Female; Humans; Leukemia; Male; Methods; Occupational Disea | 1974 |
[Symptoms of leukemia development in chronic benzene poisoning].
Topics: Benzene; Blood Cell Count; Bone Marrow Examination; Humans; Karyotyping; Leukemia | 1969 |
[Karyotype in preleukemic and preneoplastic conditions].
Topics: Anemia; Antineoplastic Agents; Benzene; Chloramphenicol; Chromosome Aberrations; Humans; Karyotyping | 1970 |
[Chromosome studies after chronic benzol exposure].
Topics: Acute Disease; Adult; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Karyotyping; | 1972 |
[General pathology of blood diseases due to non-hemolytic chemical agents. Special reference to myelopathies and cryptogenetic leukemia].
Topics: Acute Disease; Benzene; Bone Marrow Diseases; Chloramphenicol; Hematologic Diseases; Hemoglobinuria, | 1972 |
[Never start a therpy when the diagnosis is not certain. A firm point in the fight against leukemia].
Topics: Benzene; Diagnostic Errors; Humans; Leukemia; Leukemia, Radiation-Induced | 1972 |
Carcinogenic activity of 5-hydroxy-3,4-benzopyrene.
Topics: Adenoma; Animals; Benzene; Benzopyrenes; Carcinogens; Fibrosarcoma; Injections, Intradermal; Injecti | 1971 |
[Protein composition of the blood in leukemia caused by the effect of benzol and its changes under the effect of corticosteroid therapy].
Topics: Adult; Benzene; Blood Proteins; Blood Transfusion; Dexamethasone; Electrophoresis, Paper; Female; Hu | 1971 |
[Leukemias and lymph gland tumors due to benzene: etiological and general pathological aspects].
Topics: Benzene; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; L | 1969 |
[Etiological role of benzene in 2 supposedly cryptogenetic fatal hemopathies].
Topics: Adult; Benzene; Carcinogens; Environmental Exposure; Female; Humans; Leukemia; Leukemia, Myeloid, Ac | 1969 |
[Benzene hydrocarbons and severe hemopathies].
Topics: Adolescent; Adult; Aged; Benzene; Benzene Derivatives; Female; Hematologic Diseases; Hematopoietic S | 1970 |
[Benzene leukosis in the Paris area from 1950 to 1965].
Topics: Adult; Aged; Benzene; Female; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Paris | 1967 |
[New discussable problems of modern leukosology].
Topics: Animals; Benzene; Cats; Dogs; Humans; Leukemia; Mice; Viruses | 1968 |
[Unknown benzene exposures. Their systematic detection during severe hemopathies, (Survey of 200 hospitalized hemopathic patients)].
Topics: Benzene; France; Health Surveys; Hematologic Diseases; Humans; Leukemia; Occupational Diseases | 1968 |
[Leukemia as a reaction to poisons and drugs? Discussion of a hypothesis].
Topics: Analgesics; Benzene; Chloramphenicol; Leukemia | 1969 |
[Benzene leukemia].
Topics: Benzene; Blood Sedimentation; Chromosome Aberrations; Disability Evaluation; Environmental Exposure; | 1969 |
[Occupational leukemogenesis].
Topics: Anemia, Aplastic; Benzene; Humans; Leukemia; Occupational Diseases; Radiology | 1966 |