benzene has been researched along with Hematologic Diseases in 112 studies
Hematologic Diseases: Disorders of the blood and blood forming tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gender differences in risk for leukemia and other selected and combined disease categories were examined by major occupational category for 74,828 benzene-exposed workers compared to 35,805 unexposed workers from 12 cities in China." | 7.69 | Gender differences in hematopoietic and lymphoproliferative disorders and other cancer risks by major occupational group among workers exposed to benzene in China. ( Chow, WH; Dosemeci, M; Hayes, RB; Jiang, ZL; Li, GL; Linet, MS; Wacholder, S; Wang, YZ; Yin, SN; Zhang, WU, 1994) |
| "Gender differences in risk for leukemia and other selected and combined disease categories were examined by major occupational category for 74,828 benzene-exposed workers compared to 35,805 unexposed workers from 12 cities in China." | 3.69 | Gender differences in hematopoietic and lymphoproliferative disorders and other cancer risks by major occupational group among workers exposed to benzene in China. ( Chow, WH; Dosemeci, M; Hayes, RB; Jiang, ZL; Li, GL; Linet, MS; Wacholder, S; Wang, YZ; Yin, SN; Zhang, WU, 1994) |
| " Transgenic cytochrome P450 IIE1 mice may help in understanding further toxic manifestations of benzene." | 2.43 | Biochemical toxicity of benzene. ( Rana, SV; Verma, Y, 2005) |
| " Using the results from 17-week studies, doses for the 2-year studies were selected based on clinical observations (tremors in higher dosed mice), on clinical pathologic findings (lymphoid depletion in rats and leukopenia in mice), and on body weight effects." | 2.38 | Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice. ( Chrisp, CE; DeMarini, DM; Eustis, S; Haseman, JK; Huff, JE; Jacobs, AC; Maronpot, RR; Persing, RL; Peters, AC, 1989) |
| "The clinical and hematologic picture of aplastic anemia resulting from benzene exposure is not different from classical aplastic anemia; in some cases, mild bilirubinemia, changes in osmotic fragility, increase in lactic dehydrogenase and fecal urobilinogen, and occasionally some neurological abnormalities are found." | 2.38 | Hematotoxicity and carcinogenicity of benzene. ( Aksoy, M, 1989) |
| " Some ethylene glycol ethers are also toxic to bone marrow." | 2.37 | Kidney disorders and hematotoxicity from organic solvent exposure. ( Bernard, A; Buchet, JP; Lauwerys, R; Viau, C, 1985) |
| " The main objective of this study was to ascertain whether polymorphism of GSTP1, GSTM1, GSTT1 and CYP2E1 genes might influence susceptibility to the adverse effects of benzene among employees of a petrochemical plant." | 1.48 | Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity. ( Bazzaz, JT; Mansoori, Y; Neghab, M; Nejat, S; Nourozi, MA; Shahtaheri, SJ, 2018) |
| "Benzene is a primary industrial chemical and a ubiquitous environmental pollutant." | 1.46 | Association between Promoter Methylation of Gene ERCC3 and Benzene Hematotoxicity. ( Hou, F; Li, G; Lin, F; Wang, Q; Xing, C; Xu, P; Zheng, M; Zhu, C, 2017) |
| "Benzene is an established human hematotoxicant and leukemogen." | 1.40 | Long non-coding RNA NR_045623 and NR_028291 involved in benzene hematotoxicity in occupationally benzene-exposed workers. ( Bai, W; Gao, A; Niu, P; Tian, L; Yang, G; Yang, J, 2014) |
| "However, compensable occupational diseases involve the additional layer of legal systems and social welfare policies as well." | 1.40 | Compensation for work-related hematologic, liver, and infectious diseases. ( Kang, DM; Kim, JW, 2014) |
| "Benzene is an important industrial chemical and widespread environmental pollutant known to induce leukemia and other blood disorders." | 1.39 | Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers. ( Chen, Q; Guo, X; Hou, L; Li, G; Liu, X; Wang, QF; Xing, C; Zhang, L; Zheng, M; Zou, Z, 2013) |
| "Benzene is an important industrial chemical and an environmental contaminant, but the pathogenesis of hematotoxicity induced by chronic occupational benzene exposure (HCOBE) remains to be elucidated." | 1.38 | iTRAQ-based proteomic profiling of human serum reveals down-regulation of platelet basic protein and apolipoprotein B100 in patients with hematotoxicity induced by chronic occupational benzene exposure. ( Chen, C; Chen, J; Chen, S; Huang, H; Huang, M; Huang, Z; Lai, G; Lang, L; Liang, W; Qiu, X; Wang, H; Wu, B; Xia, L; Zheng, Q, 2012) |
| "Benzene is an established human haematotoxin, with substantial interindividual variation in benzene-induced toxicity." | 1.35 | Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. ( Berndt, SI; Chanock, S; Hosgood, HD; Lan, Q; Li, G; Rothman, N; Shen, M; Smith, M; Vermeulen, R; Yeager, M; Yin, S; Yuenger, J; Zhang, L, 2009) |
| "Benzene is a recognized hematotoxin and leukemogen but its mechanism of action and the role of genetic susceptibility are still unclear." | 1.33 | Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene. ( Alter, BP; Chanock, S; Dosemeci, M; Forrest, MS; Hayes, RB; Kim, S; Lan, Q; Li, G; Linet, M; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Waidyanatha, S; Weinberg, RS; Welch, R; Yeager, M; Yin, S; Zhang, L, 2005) |
| "NAD(P)H: quinone oxidoreductase-1 (NQO1) detoxifies benzoquinones, proposed toxic metabolites of benzene." | 1.32 | Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. ( Abernethy, DJ; Bauer, AK; Borghoff, S; Butterworth, BE; Everitt, J; Faiola, B; Gonzalez, FJ; Jaiswal, AK; Marchan, R; Parkinson, H; Pluta, LJ; Recio, L; Roberts, K; Wong, VA, 2003) |
| "Benzene is a human carcinogen; exposure to benzene can result in aplastic anemia and leukemia." | 1.29 | Differences in xenobiotic detoxifying activities between bone marrow stromal cells from mice and rats: implications for benzene-induced hematotoxicity. ( Li, Y; Trush, MA; Zhu, H, 1995) |
| "Benzene is a well-established hematotoxin." | 1.29 | Hematotoxicity among Chinese workers heavily exposed to benzene. ( Bechtold, WE; Blot, W; Dosemeci, M; Hayes, RB; Li, GL; Linet, M; Lu, W; Marti, GE; Rothman, N; Smith, MT; Titenko-Holland, N; Wang, YZ; Xi, LQ; Yin, SN; Zhang, LP, 1996) |
| " This is in accordance with the principles of modern occupational medicine which requires identification of early changes and prevention of irreversible benzene induced toxic changes in the haematopoietic system." | 1.28 | [Early detection of the toxic effects of benzene on the hematopoietic system--the imperative of modern occupational medicine]. ( Bogadi-Sare, A, 1992) |
| "Benzene treatment of mice also resulted in enhanced chemotaxis and production of hydrogen peroxide by bone marrow granulocytes and mononuclear phagocytes." | 1.28 | Alterations in the morphology and functional activity of bone marrow phagocytes following benzene treatment of mice. ( Laskin, DL; MacEachern, L; Snyder, R, 1992) |
| "No hydroquinone formation was detected in the absence of myeloperoxidase." | 1.28 | Hydroxylation of phenol to hydroquinone catalyzed by a human myeloperoxidase-superoxide complex: possible implications in benzene-induced myelotoxicity. ( Kolachana, P; Smith, MT; Subrahmanyam, VV, 1991) |
| " Hydroquinone (HQ), a toxic bone marrow (BM) metabolite of BZ, causes time- and concentration-dependent inhibition of processing of the 34-Kd pre-interleukin-1 alpha (IL-1 alpha) to the 17-Kd mature cytokine in murine P388D1 macrophages and BM stromal macrophages, as measured by Western immunoblots of cell lysate proteins using a polyclonal rabbit antimurine IL-1 alpha antibody." | 1.28 | Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha. ( Kalf, GF; Renz, JF, 1991) |
| "Benzene is a potent carcinogen in CBA/Ca mice." | 1.28 | Hematotoxicity and carcinogenicity of inhaled benzene. ( Bullis, JE; Cronkite, EP; Drew, RT; Hirabayashi, Y; Inoue, T, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (58.04) | 18.7374 |
| 1990's | 16 (14.29) | 18.2507 |
| 2000's | 15 (13.39) | 29.6817 |
| 2010's | 16 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, CB | 1 |
| Mota, CL | 1 |
| Almeida, YR | 1 |
| Emídio, V | 1 |
| Fonseca, ASA | 1 |
| Mitri, S | 1 |
| Moreira, JC | 1 |
| Zheng, M | 2 |
| Lin, F | 1 |
| Hou, F | 1 |
| Li, G | 6 |
| Zhu, C | 1 |
| Xu, P | 1 |
| Xing, C | 2 |
| Wang, Q | 1 |
| D'Andrea, MA | 2 |
| Reddy, GK | 2 |
| Nourozi, MA | 1 |
| Neghab, M | 1 |
| Bazzaz, JT | 1 |
| Nejat, S | 1 |
| Mansoori, Y | 1 |
| Shahtaheri, SJ | 1 |
| Qian, S | 1 |
| Han, Y | 1 |
| Shi, Y | 1 |
| Xu, W | 1 |
| Zhu, Y | 1 |
| Jiang, S | 1 |
| Chen, Y | 1 |
| Yu, Z | 1 |
| Zhang, S | 2 |
| Yang, Y | 1 |
| Yu, K | 1 |
| Chen, Q | 1 |
| Zhang, L | 4 |
| Zou, Z | 1 |
| Hou, L | 1 |
| Wang, QF | 1 |
| Liu, X | 1 |
| Guo, X | 1 |
| Kowalówka-Zawieja, J | 1 |
| Zielińska-Psuja, B | 1 |
| Przystanowicz, J | 1 |
| Sommerfeld, K | 1 |
| Singh, O | 1 |
| Bai, W | 1 |
| Yang, J | 1 |
| Yang, G | 1 |
| Niu, P | 1 |
| Tian, L | 1 |
| Gao, A | 1 |
| Kim, JW | 1 |
| Kang, DM | 1 |
| AUDOYE, H | 1 |
| ROUX, M | 1 |
| RAYNARD, R | 1 |
| IMBERT, C | 1 |
| D'ESHOUGUES, JR | 1 |
| Hosgood, HD | 2 |
| Shen, M | 3 |
| Berndt, SI | 1 |
| Vermeulen, R | 3 |
| Yin, S | 4 |
| Yeager, M | 2 |
| Yuenger, J | 1 |
| Rothman, N | 4 |
| Chanock, S | 3 |
| Smith, M | 1 |
| Lan, Q | 3 |
| Kelsey, KT | 1 |
| BOWERS, VH | 1 |
| Ibrahim, KS | 1 |
| Saleh, ZA | 1 |
| Farrag, AR | 1 |
| Shaban, EE | 1 |
| Lee, KM | 1 |
| Smith, MT | 4 |
| Huang, Z | 1 |
| Wang, H | 1 |
| Huang, H | 1 |
| Xia, L | 1 |
| Chen, C | 1 |
| Qiu, X | 1 |
| Chen, J | 1 |
| Chen, S | 1 |
| Liang, W | 1 |
| Huang, M | 1 |
| Lang, L | 1 |
| Zheng, Q | 1 |
| Wu, B | 1 |
| Lai, G | 1 |
| Hosokawa, M | 1 |
| Asami, M | 1 |
| Yoshino, T | 1 |
| Tsujimura, N | 1 |
| Takahashi, M | 1 |
| Nakasono, S | 1 |
| Tanaka, T | 1 |
| Matsunaga, T | 1 |
| Haro-García, L | 1 |
| Vélez-Zamora, N | 1 |
| Aguilar-Madrid, G | 1 |
| Guerrero-Rivera, S | 1 |
| Sánchez-Escalante, V | 1 |
| Muñoz, SR | 1 |
| Mezones-Holguín, E | 1 |
| Juárez-Pérez, C | 1 |
| Qu, Q | 1 |
| Shore, R | 1 |
| Jin, X | 1 |
| Chen, LC | 1 |
| Cohen, B | 1 |
| Melikian, AA | 1 |
| Eastmond, D | 1 |
| Rappaport, SM | 2 |
| Li, H | 1 |
| Waidyanatha, S | 2 |
| Li, Y | 2 |
| Mu, R | 1 |
| Zhang, X | 1 |
| Li, K | 1 |
| Lee, CR | 1 |
| Yoo, CI | 1 |
| Lee, JH | 1 |
| Kim, SR | 1 |
| Kim, Y | 1 |
| Bauer, AK | 2 |
| Faiola, B | 2 |
| Abernethy, DJ | 2 |
| Marchan, R | 2 |
| Pluta, LJ | 2 |
| Wong, VA | 3 |
| Roberts, K | 1 |
| Jaiswal, AK | 1 |
| Gonzalez, FJ | 2 |
| Butterworth, BE | 2 |
| Borghoff, S | 1 |
| Parkinson, H | 1 |
| Everitt, J | 1 |
| Recio, L | 2 |
| Borghoff, SJ | 1 |
| Everitt, JI | 1 |
| Yoon, BI | 2 |
| Li, GX | 2 |
| Kitada, K | 1 |
| Kawasaki, Y | 2 |
| Igarashi, K | 1 |
| Kodama, Y | 2 |
| Inoue, T | 4 |
| Kobayashi, K | 1 |
| Kanno, J | 2 |
| Kim, DY | 1 |
| Hirabayashi, Y | 3 |
| BOUSSER, J | 3 |
| ALBAHARY, C | 3 |
| TARA, S | 3 |
| PATERNI, L | 8 |
| GERMINI, P | 1 |
| DOTTA, F | 1 |
| CREPET, M | 1 |
| PRATO, V | 1 |
| GIAMMARINARO, G | 1 |
| TEODORI, S | 2 |
| RUSSO, G | 2 |
| APPUHN, E | 1 |
| GOLDECK, H | 1 |
| TURA, S | 1 |
| D'ANTUONO, G | 1 |
| MORELLI, A | 1 |
| MASSEI, G | 3 |
| MARINAI, M | 1 |
| SAITA, G | 2 |
| MOREO, L | 1 |
| PAOLINO, W | 2 |
| VERCELLINO, E | 2 |
| VILLANI, C | 2 |
| ZANOBINI, R | 1 |
| GUIDICINI, F | 1 |
| COSCIA, GC | 2 |
| PERRELLI, G | 2 |
| MEO, G | 1 |
| GALLINELLI, R | 1 |
| TRALDI, A | 1 |
| DEDOMINICIS, G | 1 |
| ERSLEV, AJ | 1 |
| PIGUET, H | 1 |
| MERKER, H | 1 |
| Bogadi-Sare, A | 2 |
| Zavalić, M | 1 |
| Turk, R | 1 |
| Rivedal, E | 1 |
| Witz, G | 1 |
| Rana, SV | 1 |
| Verma, Y | 1 |
| Irons, RD | 1 |
| Lv, L | 1 |
| Gross, SA | 1 |
| Ye, X | 1 |
| Bao, L | 1 |
| Wang, XQ | 1 |
| Ryder, J | 1 |
| Armstrong, TW | 1 |
| Zhou, Y | 1 |
| Miao, L | 1 |
| Le, AT | 1 |
| Kerzic, PJ | 1 |
| Ni, W | 1 |
| Fu, H | 1 |
| Pyszel, A | 1 |
| Wróbel, T | 1 |
| Szuba, A | 1 |
| Andrzejak, R | 1 |
| Forrest, MS | 1 |
| Hayes, RB | 3 |
| Linet, M | 2 |
| Dosemeci, M | 3 |
| Alter, BP | 1 |
| Weinberg, RS | 1 |
| Welch, R | 1 |
| Kim, S | 1 |
| Tsuboi, I | 1 |
| Kurokawa, Y | 1 |
| Yodoi, J | 1 |
| White, MC | 1 |
| Infante, PF | 1 |
| Walker, B | 1 |
| Baarson, KA | 1 |
| Snyder, CA | 1 |
| Green, JD | 1 |
| Sellakumar, A | 2 |
| Goldstein, BD | 3 |
| Albert, RE | 1 |
| Harigaya, K | 1 |
| Miller, ME | 1 |
| Cronkite, EP | 2 |
| Drew, RT | 2 |
| Stobbe, H | 1 |
| Zhu, H | 1 |
| Trush, MA | 1 |
| Li, GL | 2 |
| Linet, MS | 1 |
| Yin, SN | 2 |
| Wang, YZ | 2 |
| Chow, WH | 1 |
| Jiang, ZL | 1 |
| Wacholder, S | 1 |
| Zhang, WU | 1 |
| Khristeva, V | 1 |
| Mirchev, N | 1 |
| Karacić, V | 1 |
| Mikulandra, O | 1 |
| Cala, D | 1 |
| Marković, V | 1 |
| Zorić, A | 1 |
| Ruiz, MA | 1 |
| Vassallo, J | 1 |
| de Souza, CA | 1 |
| Krishnan, K | 1 |
| Pelekis, M | 1 |
| Ward, E | 1 |
| Hornung, R | 1 |
| Morris, J | 1 |
| Rinsky, R | 1 |
| Wild, D | 1 |
| Halperin, W | 1 |
| Guthrie, W | 1 |
| Bechtold, WE | 1 |
| Marti, GE | 1 |
| Xi, LQ | 1 |
| Lu, W | 1 |
| Titenko-Holland, N | 1 |
| Zhang, LP | 1 |
| Blot, W | 1 |
| Farris, GM | 1 |
| Robinson, SN | 1 |
| Gaido, KW | 1 |
| Wong, BA | 1 |
| Hahn, WP | 1 |
| Shah, RS | 1 |
| Luebeck, EG | 1 |
| Andersen, ME | 1 |
| Krewski, D | 1 |
| Deubel, B | 1 |
| Wúllenweber, M | 1 |
| Szadkowski, D | 1 |
| Waldron, HA | 1 |
| Van den Berghe, H | 1 |
| Louwagie, A | 1 |
| Broeckaert-Van Orshoven, A | 1 |
| David, G | 1 |
| Verwilghen, R | 1 |
| Johnston, RV | 1 |
| Pinkerton, MN | 1 |
| Mensik, DC | 1 |
| Swaim, LD | 1 |
| Linscombe, VA | 1 |
| Benge, MC | 1 |
| Barna-Lloyd, G | 1 |
| Kilian, DJ | 1 |
| Synder, CA | 1 |
| Wolman, SR | 1 |
| Bromberg, I | 1 |
| Erlichman, MN | 1 |
| Laskin, S | 1 |
| Garavini, C | 1 |
| Seren, P | 1 |
| Sanderson, JH | 1 |
| Hirashima, K | 1 |
| MacEachern, L | 1 |
| Snyder, R | 1 |
| Laskin, DL | 1 |
| Burg, J | 1 |
| Gist, GL | 1 |
| Subrahmanyam, VV | 1 |
| Kolachana, P | 1 |
| Renz, JF | 1 |
| Kalf, GF | 1 |
| Huff, JE | 1 |
| Haseman, JK | 1 |
| DeMarini, DM | 1 |
| Eustis, S | 1 |
| Maronpot, RR | 1 |
| Peters, AC | 1 |
| Persing, RL | 1 |
| Chrisp, CE | 1 |
| Jacobs, AC | 1 |
| Aksoy, M | 3 |
| Bullis, JE | 1 |
| Ozeriş, S | 1 |
| Sabuncu, H | 1 |
| Inanici, Y | 1 |
| Yanardağ, R | 1 |
| Bittersohl, KU | 1 |
| Bittersohl, G | 1 |
| Lauwerys, R | 1 |
| Bernard, A | 1 |
| Viau, C | 1 |
| Buchet, JP | 1 |
| Tikhachek, ES | 1 |
| Frash, VN | 1 |
| Nau, CA | 1 |
| Neal, J | 1 |
| Thornton, M | 1 |
| Galton, DA | 1 |
| Spiers, AS | 1 |
| Forni, AM | 1 |
| Cappellini, A | 1 |
| Pacifico, E | 1 |
| Vigliani, EC | 1 |
| Kissling, M | 1 |
| Speck, B | 1 |
| Gribova, IA | 1 |
| Zorina, LA | 1 |
| Forni, A | 1 |
| Pollini, G | 1 |
| Biscaldi, GP | 1 |
| Robustelli della Cuna, G | 1 |
| Girard, R | 2 |
| Tolot, F | 2 |
| Bourret, J | 2 |
| Dinçol, K | 1 |
| Akgün, T | 1 |
| Erdem, S | 1 |
| Dinçol, G | 1 |
| Micu, D | 1 |
| Pogăceanu, P | 1 |
| Rigaut, P | 1 |
| Bertholon, J | 1 |
| Ghislandi, E | 1 |
| Annoni, S | 1 |
10 reviews available for benzene and Hematologic Diseases
| Article | Year |
|---|---|
Biochemical toxicity of benzene.
Topics: Absorption; Animals; Benzene; Bone Marrow; Carcinogens; DNA Damage; Environmental Monitoring; Hemato | 2005 |
[Effect of metals, benzene, pesticides and ethylene oxide on the haematopoietic system].
Topics: Benzene; Environmental Exposure; Environmental Pollutants; Ethylenes; Hazardous Substances; Hematolo | 2005 |
Occupational exposure to benzene: a review of carcinogenic and related health effects following the U.S. Supreme Court decision.
Topics: Animals; Benzene; Carcinogens; Chromosome Aberrations; Dose-Response Relationship, Drug; Epidemiolog | 1980 |
Hematotoxic interactions: occurrence, mechanisms and predictability.
Topics: Animals; Benzene; Carboxyhemoglobin; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dose-R | 1995 |
Benzene toxicity: a critical evaluation: hematotoxicity in humans.
Topics: Benzene; Blood Cells; Hematologic Diseases; Humans; Leukemia; Pancytopenia; Time Factors | 1977 |
Target organs. The blood.
Topics: Arsenic; Benzene; Blood Physiological Phenomena; Bone Marrow; Erythrocytes; Female; Globins; Hematol | 1979 |
Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice.
Topics: Animals; Benzene; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Female; Hematologic Di | 1989 |
Hematotoxicity and carcinogenicity of benzene.
Topics: Anemia, Aplastic; Benzene; Hematologic Diseases; Humans; Leukemia; Neoplasms; Pancytopenia | 1989 |
Kidney disorders and hematotoxicity from organic solvent exposure.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Benzene; Epidemiologic Methods; Ethers; Europe; Fe | 1985 |
Progress in the leukemias.
Topics: Alkylating Agents; Androgens; Anemia, Hemolytic, Autoimmune; Benzene; Blood Transfusion; Bone Marrow | 1971 |
102 other studies available for benzene and Hematologic Diseases
| Article | Year |
|---|---|
Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G>C and NQO1 609C>T) in Campos Elíseos residents, Duque de Caxias, Rio de Janeiro State, Brazil.
Topics: Acetylcysteine; Benzene; Biomarkers; Brazil; Causality; Chemical Industry; Creatinine; Cytochrome P- | 2019 |
Association between Promoter Methylation of Gene ERCC3 and Benzene Hematotoxicity.
Topics: Adult; Aged; Benzene; China; Cities; CpG Islands; DNA Helicases; DNA Methylation; DNA-Binding Protei | 2017 |
Benzene exposure from the BP refinery flaring incident alters hematological and hepatic functions among smoking subjects.
Topics: Adult; Aged; Air Pollutants; Benzene; Chemical Hazard Release; Environmental Exposure; Female; Hemat | 2017 |
Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity.
Topics: Adult; Air Pollutants, Occupational; Benzene; Cross-Sectional Studies; Cytochrome P450 Family 2; Ery | 2018 |
Benzene induces haematotoxicity by promoting deacetylation and autophagy.
Topics: Acetylation; Adult; Animals; Antigens, CD34; Apoptosis; Autophagy; Benzene; Bone Marrow Cells; Chlor | 2019 |
Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers.
Topics: Benzene; China; Cytochrome P-450 CYP1A1; DNA Helicases; DNA Methylation; DNA-Binding Proteins; Envir | 2013 |
Influence of acetylsalicylic acid on hematotoxicity of benzene.
Topics: Animals; Aspirin; Benzene; Bone Marrow Cells; Carboxylic Ester Hydrolases; Cyclooxygenase Inhibitors | 2013 |
Health consequences of involuntary exposure to benzene following a flaring incident at British Petroleum refinery in Texas City.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzene; Biomarkers; Chemical Hazard Release; Child; Chi | 2013 |
Long non-coding RNA NR_045623 and NR_028291 involved in benzene hematotoxicity in occupationally benzene-exposed workers.
Topics: Adult; Benzene; Carcinogens; Chemical and Drug Induced Liver Injury; Computational Biology; Female; | 2014 |
Compensation for work-related hematologic, liver, and infectious diseases.
Topics: Adult; Benzene; Chemical and Drug Induced Liver Injury; Communicable Diseases; Dimethylformamide; Fe | 2014 |
Prophylaxis of benzolic hematopathies.
Topics: Benzene; Blood; Hematologic Diseases; Humans; Occupational Diseases | 1948 |
Delayed benzolic hemopathy during acute malaria.
Topics: Benzene; Disease; Hematologic Diseases; Hematopoietic System; Humans; Malaria | 1948 |
Benzolic hematopathy with intense myeloblastosis without clinical manifestations.
Topics: Benzene; Disease; Hematologic Diseases; Hematopoietic System; Humans; Leukemia, Myeloid | 1947 |
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
Topics: Benzene; DNA Helicases; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Hematologic | 2009 |
Perspectives on research and practice in occupational and environmental health: the case of benzene.
Topics: Benzene; Finland; Hematologic Diseases; History, 20th Century; Humans; Occupational Diseases; Turkey | 2010 |
Reaction of human blood-forming tissues to chronic benzene exposure.
Topics: Benzene; Disease; Hematologic Diseases; Hematopoietic System; Humans | 1947 |
Protective effects of zinc and selenium against benzene toxicity in rats.
Topics: Animal Feed; Animals; Antioxidants; Benzene; Carbonates; Dietary Supplements; Eating; Hematologic Di | 2011 |
Polymorphisms in genes involved in innate immunity and susceptibility to benzene-induced hematotoxicity.
Topics: Adult; Arachidonate 5-Lipoxygenase; Benzene; Cell Count; Cross-Sectional Studies; Female; Genetic As | 2011 |
iTRAQ-based proteomic profiling of human serum reveals down-regulation of platelet basic protein and apolipoprotein B100 in patients with hematotoxicity induced by chronic occupational benzene exposure.
Topics: Adult; Apolipoprotein B-100; Benzene; beta-Thromboglobulin; Blood Cell Count; Blotting, Western; Chr | 2012 |
Monitoring of benzene-induced hematotoxicity in mice by serial leukocyte counting using a microcavity array.
Topics: Animals; Benzene; Blood Specimen Collection; Cell Separation; Cells, Cultured; Chemical and Drug Ind | 2013 |
[Blood disorders among workers exposed to a mixture of benzene-toluene-xylene (BTX) in a paint factory].
Topics: Adult; Benzene; Chemical Industry; Cross-Sectional Studies; Hematologic Diseases; Humans; Middle Age | 2012 |
Hematological changes among Chinese workers with a broad range of benzene exposures.
Topics: Adult; Analysis of Variance; Benzene; Biomarkers; Blood Cell Count; China; Environmental Monitoring; | 2002 |
Hematological changes of children exposed to volatile organic compounds containing low levels of benzene.
Topics: Benzene; Blood Cell Count; Chemical Industry; Child; Cohort Studies; Environmental Exposure; Female; | 2002 |
Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1.
Topics: Animals; Benzene; Bone Marrow Cells; Cytochrome P-450 CYP2E1; DNA; DNA Damage; Female; Genetic Predi | 2003 |
Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
Topics: Administration, Inhalation; Animals; Benzene; Bone Marrow Cells; Cyclin-Dependent Kinase Inhibitor p | 2003 |
Mechanisms of benzene-induced hematotoxicity and leukemogenicity: cDNA microarray analyses using mouse bone marrow tissue.
Topics: Administration, Inhalation; Animals; Apoptosis; Benzene; Bone Marrow; DNA Damage; DNA Repair; Gene E | 2003 |
[Atypical hemopoietic diseases caused by benzene poisoning].
Topics: Benzene; Disease; Hematologic Diseases; Hematopoietic System; Humans | 1952 |
[Benzene blood disease: hemato-medullar dissociations, latent forms, effects of pregnancy].
Topics: Benzene; Endocrine Glands; Female; Hematologic Diseases; Humans; Poisoning; Pregnancy; Pregnancy Com | 1954 |
[Benzol hemopathy in rat, myelosis of leukemic and erythremic type, effect of splenectomy and histiocytic origin of granulocytes with annular nucleus].
Topics: Animals; Benzene; Granulocytes; Hematologic Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positi | 1954 |
[Frequency and significance of erythroblastosis in blood diseases caused by benzene].
Topics: Benzene; Hematologic Diseases; Humans; Poisoning; Polycythemia Vera | 1955 |
[Global aplastic myelosis; nosographic and clinicopathogenetic considerations with particular regard to extramedullary hemopoietic foci].
Topics: Anemia; Anemia, Aplastic; Benzene; Hematologic Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Pos | 1955 |
[ACTH treatment of blood diseases caused by benzene].
Topics: Adrenocorticotropic Hormone; Benzene; Hematologic Diseases; Humans; Poisoning | 1956 |
[The effect of ACTH on experimental benzol-induced hemopathy].
Topics: Adrenocorticotropic Hormone; Benzene; Hematologic Diseases; Humans | 1957 |
[Early & late hemopoietic diseases caused by benzol & its homologues].
Topics: Benzene; Hematologic Diseases; Humans; Occupational Diseases | 1957 |
[Report on benzene-induced erythrocyte disorders].
Topics: Acridines; Anemia; Benzene; beta-Thalassemia; Erythroblasts; Hematologic Diseases | 1958 |
[The problem of blood diseases caused by benzene].
Topics: Acridines; Benzene; Hematologic Diseases; Humans; Occupational Diseases | 1958 |
[Effect of cortisone & ACTH on experimental benzol-induced blood disease].
Topics: Acridines; Adrenocorticotropic Hormone; Benzene; Cortisone; Hematologic Diseases | 1958 |
[Thalassemia and occupational blood diseases. I. Thalassemia and chronic benzolism].
Topics: Anemia; Benzene; beta-Thalassemia; Hematologic Diseases; Humans; Occupational Diseases; Thalassemia | 1959 |
[Experimental studies of the preventive and curative effectiveness of adenine in hematological damage caused by acute benzol intoxication].
Topics: Adenine; Benzene; Drug-Related Side Effects and Adverse Reactions; Hematologic Diseases; Humans; Psy | 1959 |
[Erythrocyte survival in benzol-induced blood diseases. Experimental study with Cr-51].
Topics: Benzene; Chromium; Chromium Radioisotopes; Erythrocyte Aging; Erythrocytes; Hematologic Diseases; Ra | 1960 |
[Experimental data concerning the participation of the spleen in benzol hemopathy].
Topics: Benzene; Hematologic Diseases; Spleen | 1960 |
[CLINICAL ASPECTS OF BLOOD DISEASE CAUSED BY BENZENE].
Topics: Adolescent; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzene | 1963 |
[BENZENE BLOOD DISEASE. 3 CASES OF CHRONIC BENZENE POISONING OF WHICH 2 WERE FATAL (ACUTE LEUKEMIA, ACUTE PANMYELOPHTHISIS)].
Topics: Adrenocorticotropic Hormone; Anemia; Anemia, Myelophthisic; Anti-Bacterial Agents; Ascorbic Acid; Be | 1963 |
[CLINICAL CONTRIBUTION TO THE STUDY OF BLOOD DISEASES INDUCED BY BENZENE HYDROCARBONS AND PROBLEMS OF PREVENTION].
Topics: Adolescent; Anemia; Asthenia; Benzene; Bone Marrow Examination; Cerebral Hemorrhage; Hematologic Dis | 1963 |
[PREGNANCY AND BENZENE BLOOD DISORDER. CLINICAL CONTRIBUTION].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Benzene; Cortisone; Female; Folic Acid; Hemato | 1963 |
DRUG-INDUCED BLOOD DYSCRASIAS. I. APLASTIC ANEMIA.
Topics: Acetazolamide; Anemia; Anemia, Aplastic; Anticonvulsants; Benzene; Chloramphenicol; Chlorothiazide; | 1964 |
[TOXIC HEMOPATHIES].
Topics: Benzene; Hematologic Diseases; Lead Poisoning; Radiation Injuries; Toxicology | 1964 |
Effects of adenine on blood disease due to benzene poisoning.
Topics: Adenine; Benzene; Hematologic Diseases; Humans | 1960 |
[First case of Pelger's anomaly in benzene hemopathy; association with cellular nanism].
Topics: Benzene; Dwarfism; Hematologic Diseases; Humans; Leukocytes; Medical Records; Occupational Diseases | 1960 |
[Benzene and the early recognition of its blood-damaging effects].
Topics: Benzene; Hematologic Diseases; Humans | 1962 |
Utility of a routine medical surveillance program with benzene exposed workers.
Topics: Adult; Benzene; Female; Hematologic Diseases; Humans; Industry; Mass Screening; Middle Aged; Occupat | 2003 |
[Atypical aspects of diseases of the blood caused by benzene].
Topics: Benzene; Disease; Hematologic Diseases; Hematopoietic System; Humans | 1952 |
[Atypical aspects of blood diseases due to benzols].
Topics: Benzene; Benzoates; Hematologic Diseases; Humans | 1951 |
Benzene metabolites block gap junction intercellular communication. Role in hematotoxicity and leukemia?
Topics: Aldehydes; Animals; Benzene; Cell Communication; Cell Line; Gap Junctions; Hematologic Diseases; Hyd | 2005 |
Chronic exposure to benzene results in a unique form of dysplasia.
Topics: Adult; Autoimmunity; Benzene; Blood Cells; Bone Marrow Diseases; Female; Hematologic Diseases; Human | 2005 |
Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene.
Topics: Adult; Benzene; Cell Adhesion Molecules; Cytokines; Female; Hematologic Diseases; Hematopoiesis; Hum | 2005 |
Thioredoxin overexpression in mice, model of attenuation of oxidative stress, prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.
Topics: Animals; Benzene; Burkitt Lymphoma; Carcinogens; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P | 2006 |
The hematotoxic effects of inhaled benzene on peripheral blood, bone marrow, and spleen cells are increased by ingested ethanol.
Topics: Animals; Benzene; Body Weight; Bone Marrow Cells; Bone Marrow Diseases; Drug Interactions; Ethanol; | 1982 |
The detection of in vivo hematotoxicity of benzene by in vitro liquid bone marrow cultures.
Topics: Animals; Benzene; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Femal | 1981 |
[Risk factor benzene (author's transl)].
Topics: Anemia, Aplastic; Benzene; Hematologic Diseases; Hematopoiesis; Humans; Leukemia; Occupational Disea | 1981 |
Differences in xenobiotic detoxifying activities between bone marrow stromal cells from mice and rats: implications for benzene-induced hematotoxicity.
Topics: Animals; Benzene; Benzoquinones; Bone Marrow; Cells, Cultured; Glutathione; Hematologic Diseases; Hy | 1995 |
Gender differences in hematopoietic and lymphoproliferative disorders and other cancer risks by major occupational group among workers exposed to benzene in China.
Topics: Benzene; China; Cohort Studies; Female; Hematologic Diseases; Hematopoietic System; Humans; Leukemia | 1994 |
[Changes in the blood system under chronic toxic exposure].
Topics: Adolescent; Adult; Agricultural Workers' Diseases; Air Pollutants; Benzene; Blood; Bulgaria; Chemica | 1993 |
[Exposure to benzene and hematologic changes in workers at the Ina-Oki Drnisplast factory in Drnisa].
Topics: Benzene; Hematologic Diseases; Humans; Occupational Diseases | 1994 |
[Exposure to benzene and hematologic changes in workers at the Ina-Oki Drnisplast factory in Drnis].
Topics: Adult; Benzene; Hematologic Diseases; Humans; Middle Aged; Nervous System Diseases; Occupational Dis | 1993 |
[Hematologic changes in patients chronically exposed to benzene].
Topics: Benzene; Bone Marrow; Hematologic Diseases; Humans; Occupational Diseases; Occupational Exposure; Ri | 1993 |
Risk of low red or white blood cell count related to estimated benzene exposure in a rubberworker cohort (1940-1975)
Topics: Benzene; Case-Control Studies; Chemical Industry; Cohort Studies; Dose-Response Relationship, Drug; | 1996 |
Hematotoxicity among Chinese workers heavily exposed to benzene.
Topics: Adult; Age Distribution; Benzene; Blood Cell Count; China; Cohort Studies; Cross-Sectional Studies; | 1996 |
Benzene-induced hematotoxicity and bone marrow compensation in B6C3F1 mice.
Topics: Animals; Benzene; Blood Cell Count; Bone Marrow; Bromodeoxyuridine; Cell Differentiation; Cell Divis | 1997 |
From cyclophosphamide hematotoxicity to modeling cancer.
Topics: Animals; Benzene; Carcinogens; Cyclophosphamide; Dose-Response Relationship, Drug; Hematologic Disea | 2000 |
Biologically based risk assessment model for cyclophosphamide hematotoxicity in animal species: concluding comments.
Topics: Animals; Benzene; Cyclophosphamide; Dogs; Hematologic Diseases; Hematopoietic Stem Cells; Humans; Le | 2000 |
[Benzene-conditioned blood count changes in relation to spontaneous normal value variations (author's transl)].
Topics: Adult; Benzene; Blood Cell Count; Blood Cells; Environmental Exposure; Hematologic Diseases; Humans; | 1979 |
[Hematological damage of occupational origin in industry].
Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Benzene Derivatives; Environmental Pollutants | 1978 |
Chromosome analysis in two unusual malignant blood disorders presumably induced by benzene.
Topics: Adult; Aged; Benzene; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Hemat | 1979 |
Hematologic and myelogenous effects of inhaled benzene in the pig and the rat.
Topics: Animals; Benzene; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Female; Gases; Hematologic Disea | 1979 |
Hematotoxicity of inhaled benzene to Sprague-Dawley rats and AKR mice at 300 ppm.
Topics: Animals; Benzene; Blood Cell Count; Erythrocyte Count; Glutathione; Hematologic Diseases; L-Lactate | 1978 |
Hematologic and hemopoietic alterations following experimental benzene exposure in newts (Triturus cristatus).
Topics: Animals; Benzene; Erythrocyte Count; Hematologic Diseases; Hematopoiesis; Leukocyte Count; Liver; Ph | 1978 |
Haematological problems at work.
Topics: Anemia, Aplastic; Benzene; Carbon Monoxide Poisoning; Carboxyhemoglobin; Glucosephosphate Dehydrogen | 1976 |
[Secondary leukemia and the countermeasures].
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzene; Down Syndrome; Hematologic Diseases; Hodgki | 1992 |
[Early detection of the toxic effects of benzene on the hematopoietic system--the imperative of modern occupational medicine].
Topics: Benzene; Hematologic Diseases; Humans; Maximum Allowable Concentration; Occupational Diseases | 1992 |
Alterations in the morphology and functional activity of bone marrow phagocytes following benzene treatment of mice.
Topics: Animals; Benzene; Bone Marrow; Cell Differentiation; Chemotaxis; Granulocytes; Hematologic Diseases; | 1992 |
Chronic low-level exposure to benzene.
Topics: Adult; Benzene; Dose-Response Relationship, Drug; Environmental Exposure; Hematologic Diseases; Huma | 1992 |
Hydroxylation of phenol to hydroquinone catalyzed by a human myeloperoxidase-superoxide complex: possible implications in benzene-induced myelotoxicity.
Topics: Benzene; Hematologic Diseases; Histidine; Humans; Hydroquinones; Hydroxylation; Mannitol; Neutrophil | 1991 |
Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha.
Topics: Animals; Benzene; Blotting, Western; Bone Marrow Cells; Cells, Cultured; DNA; Hematologic Diseases; | 1991 |
Hematotoxicity and carcinogenicity of inhaled benzene.
Topics: Administration, Inhalation; Animals; Benzene; Carcinogens; Dose-Response Relationship, Drug; Drug Ad | 1989 |
Exposure to benzene in Turkey between 1983 and 1985: a haematological study on 231 workers.
Topics: Adolescent; Adult; Air Pollutants, Occupational; Benzene; Hematologic Diseases; Hematologic Tests; H | 1987 |
[Epidemiological studies of hematotoxic and hepatotoxic effects of benzene and benzene-containing solvent mixtures].
Topics: Anemia, Aplastic; Benzene; Chemical and Drug Induced Liver Injury; Drug Combinations; Fatty Liver; G | 1985 |
[Autoimmune processes in experimental benzene hemopathy].
Topics: Animals; Autoantibodies; Autoantigens; Benzene; Bone Marrow; Hematologic Diseases; Liver; Plasma Cel | 1973 |
[Interpretation and reflections of blood disease pictures due to benzene in the general field of blood diseases].
Topics: Benzene; Hematologic Diseases; Humans | 1965 |
C9-C12 fractions obtained from petroleum distillates. An evaluation of their potential toxicity.
Topics: Animals; Benzene; Cataract; Cycloparaffins; Eye; Haplorhini; Hematologic Diseases; Kidney; Liver; Lu | 1966 |
[General pathology of blood diseases due to non-hemolytic chemical agents. Special reference to myelopathies and cryptogenetic leukemia].
Topics: Acute Disease; Benzene; Bone Marrow Diseases; Chloramphenicol; Hematologic Diseases; Hemoglobinuria, | 1972 |
Chromosome changes and their evolution in subjects with past exposure to benzene.
Topics: Adult; Aneuploidy; Benzene; Blood Cell Count; Bone Marrow Cells; Cell Division; Chromosome Aberratio | 1971 |
Chromosome aberrations in experimental benzene intoxication.
Topics: Animals; Benzene; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Cytogene | 1971 |
[The dynamics of peripheral blood changes in the late period of chronic benzene poisoning].
Topics: Benzene; Chronic Disease; Female; Hematologic Diseases; Humans; Male | 1971 |
Chromosome studies in workers exposed to benzene or toluene or both.
Topics: Adult; Benzene; Blood Cell Count; Chemical Industry; Chromosome Aberrations; Hematologic Diseases; H | 1971 |
[Chromosome changes of the lumphocytes discovered after five years in subjects with benzolic hemopathy].
Topics: Adult; Benzene; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1-3; Chromosomes, | 1969 |
[Benzene hydrocarbons and severe hemopathies].
Topics: Adolescent; Adult; Aged; Benzene; Benzene Derivatives; Female; Hematologic Diseases; Hematopoietic S | 1970 |
Haematological effects of chronic benzene poisoning in 217 workers.
Topics: Adolescent; Adult; Anemia, Aplastic; Anemia, Hypochromic; Basophils; Benzene; Blood Platelet Disorde | 1971 |
[Hematological disorders in benzene poisoning].
Topics: Benzene; Hematologic Diseases; Humans | 1971 |
[Reflections on the hemopathic disorders caused by benzene in the general field of hemopathies].
Topics: Benzene; Hematologic Diseases; Humans; Occupational Diseases | 1968 |
[Unknown benzene exposures. Their systematic detection during severe hemopathies, (Survey of 200 hospitalized hemopathic patients)].
Topics: Benzene; France; Health Surveys; Hematologic Diseases; Humans; Leukemia; Occupational Diseases | 1968 |
[On corticosteroid therapy in benzene hemopathy].
Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Benzene; Female; Hematologic Diseases; Humans; Mal | 1966 |