Page last updated: 2024-10-16

benzene and Genetic Predisposition

benzene has been researched along with Genetic Predisposition in 61 studies

Research Excerpts

ExcerptRelevanceReference
"Individual variations in the capacity of DNA repair machinery to relieve benzene-induced DNA damage may be the key to developing chronic benzene poisoning (CBP), an increasingly prevalent occupational disease in China."7.81Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population. ( Cai, Y; Gao, L; Jin, C; Lu, X; Wu, S; Xiao, M; Xiao, S; Xue, P; Yang, J; Zhang, G; Zhang, Q; Zheng, X, 2015)
"Leukemia is the most common cancer in children."5.30Biomarkers of leukemia risk: benzene as a model. ( Smith, MT; Zhang, L, 1998)
"Mutations at CYP2E1 RsaI/PstI can enhance the expression of CYP2E1 and this suggests individuals with the mutated gene have increased susceptibility to chronic benzene poisoning."3.81[Analysis of cytochrome P450 2E1 RsaI/PstI and DraI polymorphisms in workers exposed to benzene]. ( Chen, Z; Ling, J; Liu, Y; Tu, H; Wang, D; Wang, J; Wu, X, 2015)
"Individual variations in the capacity of DNA repair machinery to relieve benzene-induced DNA damage may be the key to developing chronic benzene poisoning (CBP), an increasingly prevalent occupational disease in China."3.81Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population. ( Cai, Y; Gao, L; Jin, C; Lu, X; Wu, S; Xiao, M; Xiao, S; Xue, P; Yang, J; Zhang, G; Zhang, Q; Zheng, X, 2015)
"Chronic exposure to benzene results in progressive decline of hematopoietic function and may lead to the onset of various disorders, including aplastic anemia, myelodysplastic syndrome, and leukemia."3.72Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression. ( Abernethy, DJ; Faiola, B; Fuller, ES; Pluta, L; Recio, L; Rose, J; Wong, VA, 2004)
" We present two hypothetical scenarios: (1) benzene-induced cancer with few expected cases, and (2) chronic beryllium disease with many expected cases."3.70A cost-benefit analysis of genetic screening for susceptibility to occupational toxicants. ( Lomax, GP; Nicas, M, 1999)
"Benzene is a ubiquitous occupational and environmental pollutant."2.53Biomarkers of susceptibility following benzene exposure: influence of genetic polymorphisms on benzene metabolism and health effects. ( Carbonari, D; Chiarella, P; Iavicoli, S; Mansi, A; Pigini, D; Tranfo, G, 2016)
" People vary greatly in their susceptibility to adverse health outcomes from benzene exposure."2.41[Individual susceptibility to hematotoxicity from benzene exposure and the genetic polymorphism of metabolic enzymes]. ( Chen, Y; Li, G; Yin, S, 2002)
" The main objective of this study was to ascertain whether polymorphism of GSTP1, GSTM1, GSTT1 and CYP2E1 genes might influence susceptibility to the adverse effects of benzene among employees of a petrochemical plant."1.48Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity. ( Bazzaz, JT; Mansoori, Y; Neghab, M; Nejat, S; Nourozi, MA; Shahtaheri, SJ, 2018)
"To provide better understanding of genetic susceptibility for health risk among current benzene-exposed workers."1.46Association Between Polymorphisms of Metabolic Enzyme Genes and Chromosomal Damage in Benzene-Exposed Workers in China. ( Au, W; Fang, Y; Hu, W; Sun, P; Wu, HT; Xia, ZL; Ye, YJ; Zhang, GH; Zhou, LF, 2017)
"Benzene is an important industrial chemical and widespread environmental pollutant known to induce leukemia and other blood disorders."1.39Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers. ( Chen, Q; Guo, X; Hou, L; Li, G; Liu, X; Wang, QF; Xing, C; Zhang, L; Zheng, M; Zou, Z, 2013)
"Toluene exposure is a potential confounder for some peripheral blood effects, pointing to the need to scrutinize levels of both compounds in the occupational environment."1.36Peripheral blood effects in benzene-exposed workers. ( Armstrong, TW; Bird, MG; Chen, M; Fu, H; Irons, RD; Kerzic, PJ; Lavelle, K; Lin, L; Nicolich, MJ; Robert Schnatter, A; Zhou, Y, 2010)
" To determine whether the genotype at these loci might influence susceptibility to the adverse effects of benzene exposure, 208 Bulgarian petrochemical workers and controls, whose exposure to benzene was determined by active personal sampling, were studied."1.35Genetic susceptibility to benzene toxicity in humans. ( Bolognesi, C; Farmer, P; Garte, S; Merlo, F; Popov, T; Taioli, E, 2008)
"Benzene is an established human haematotoxin, with substantial interindividual variation in benzene-induced toxicity."1.35Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. ( Berndt, SI; Chanock, S; Hosgood, HD; Lan, Q; Li, G; Rothman, N; Shen, M; Smith, M; Vermeulen, R; Yeager, M; Yin, S; Yuenger, J; Zhang, L, 2009)
"Benzene is a leukemogen, and exposure to benzene is an occupational hazard in the petroleum refining industries."1.35Association of the NQO1, MPO, and XRCC1 polymorphisms and chromosome damage among workers at a petroleum refinery. ( Choi, JY; Chung, HW; Kim, YJ; Paek, D, 2008)
"Benzene is a recognized haematotoxin and leukaemogen, but its mechanism of action and the role of genetic susceptibility are still unclear."1.34Genetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations. ( Chen, Y; Ji, Z; Li, G; Liu, L; Ma, D; Xiu, X; Xu, J; Yin, S, 2007)
"Benzene is a recognized hematotoxicant and carcinogen that produces genotoxic damage."1.33Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity. ( Chanock, S; Forrest, MS; Guo, W; Hayes, RB; Lan, Q; Li, G; Linet, M; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Welch, R; Yeager, M; Yin, S; Zhang, L, 2006)
"NAD(P)H: quinone oxidoreductase-1 (NQO1) detoxifies benzoquinones, proposed toxic metabolites of benzene."1.32Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. ( Abernethy, DJ; Bauer, AK; Borghoff, S; Butterworth, BE; Everitt, J; Faiola, B; Gonzalez, FJ; Jaiswal, AK; Marchan, R; Parkinson, H; Pluta, LJ; Recio, L; Roberts, K; Wong, VA, 2003)
"Benzene has been implicated as an environmental risk factor in leukaemia and other haematological diseases."1.32Urban benzene exposure and oxidative DNA damage: influence of genetic polymorphisms in metabolism genes. ( Autrup, H; Hertel, O; Loft, S; Skov, H; Sørensen, M, 2003)
" Here we compared the toxic effects of benzene on mice (C57BL/6 and 129/Sv) homozygous for the wild-type Prkdc allele and mice (129/SvJ) homozygous for a Prkdc functional polymorphism that leads to diminished DNA-PK activity and enhanced apoptosis in response to radiation-induced damage."1.32Variations in Prkdc and susceptibility to benzene-induced toxicity in mice. ( Abernethy, DJ; Bauer, AK; Everitt, JI; Faiola, B; Fuller, ES; Mangum, JB; Pluta, LJ; Recio, L; Wong, VA, 2003)
"Among the nonexposed, genetic susceptibility alone did not confer a significant adverse effect."1.31Genetic susceptibility to benzene and shortened gestation: evidence of gene-environment interaction. ( Chen, D; Christiani, DC; Niu, T; Ryan, L; Smith, T; Wang, L; Wang, X; Wang, Z; Xu, X; Zuckerman, B, 2000)
"Leukemia is the most common cancer in children."1.30Biomarkers of leukemia risk: benzene as a model. ( Smith, MT; Zhang, L, 1998)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (8.20)18.2507
2000's37 (60.66)29.6817
2010's15 (24.59)24.3611
2020's4 (6.56)2.80

Authors

AuthorsStudies
Jafari Roshan, S1
Mansoori, Y3
Hosseini, SR1
Sabour, D1
Daraei, A1
Hausman-Cohen, SR1
Hausman-Cohen, LJ1
Williams, GE1
Bilich, CE1
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J3
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W2
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X3
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y8
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Ma, Q1
Wang, J5
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L3
Yan, Z2
Wang, Y2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X2
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C4
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L2
Zhu, J2
Zhang, L9
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X6
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W2
Zhang, Y4
Wu, X2
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J2
Ge, J1
Hu, J2
Wang, H2
Liu, Y5
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D2
Wu, D4
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Li, C1
Chen, W2
Hu, X1
Zhang, F1
Wei, H1
Wang, Z2
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q3
Lyu, Y1
Huang, J1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
Ryan, CM1
Bellingham, G1
Singh, M2
Waseem, R1
Eckert, DJ1
Chung, F1
Hegde, H1
Shimpi, N1
Panny, A1
Glurich, I1
Christie, P1
Acharya, A1
English, KL1
Downs, M1
Goetchius, E1
Buxton, R1
Ryder, JW1
Ploutz-Snyder, R1
Guilliams, M1
Scott, JM1
Ploutz-Snyder, LL1
Martens, C1
Goplen, FK1
Aasen, T1
Gjestad, R1
Nordfalk, KF1
Nordahl, SHG1
Inoue, T1
Soshi, S1
Kubota, M1
Marumo, K1
Mortensen, NP1
Caffaro, MM1
Patel, PR2
Uddin, MJ1
Aravamudhan, S1
Sumner, SJ1
Fennell, TR1
Gal, RL1
Cohen, NJ1
Kruger, D1
Beck, RW1
Bergenstal, RM1
Calhoun, P1
Cushman, T1
Haban, A1
Hood, K1
Johnson, ML1
McArthur, T1
Olson, BA1
Weinstock, RS1
Oser, SM1
Oser, TK1
Bugielski, B1
Strayer, H1
Aleppo, G1
Maruyama, H1
Hirayama, K1
Yamashita, M1
Ohgi, K1
Tsujimoto, R1
Takayasu, M1
Shimohata, H1
Kobayashi, M1
Buscagan, TM1
Rees, DC1
Jaborek, JR1
Zerby, HN1
Wick, MP1
Fluharty, FL1
Moeller, SJ1
Razavi, P1
Dickler, MN1
Shah, PD1
Toy, W1
Brown, DN1
Won, HH1
Li, BT1
Shen, R1
Vasan, N1
Modi, S1
Jhaveri, K1
Caravella, BA1
Patil, S1
Selenica, P1
Zamora, S1
Cowan, AM1
Comen, E1
Singh, A1
Covey, A1
Berger, MF1
Hudis, CA1
Norton, L1
Nagy, RJ1
Odegaard, JI1
Lanman, RB1
Solit, DB1
Robson, ME1
Lacouture, ME1
Brogi, E1
Reis-Filho, JS1
Moynahan, ME1
Scaltriti, M1
Chandarlapaty, S1
Papouskova, K1
Moravcova, M1
Masrati, G1
Ben-Tal, N1
Sychrova, H1
Zimmermannova, O1
Fang, J1
Fan, Y1
Luo, T2
Su, H1
Tsetseris, L1
Anthopoulos, TD1
Liu, SF1
Zhao, K1
Sacan, O1
Turkyilmaz, IB1
Bayrak, BB1
Mutlu, O1
Akev, N1
Yanardag, R1
Gruber, S1
Kamnoedboon, P1
Özcan, M1
Srinivasan, M1
Jo, YH1
Oh, HK1
Jeong, SY1
Lee, BG1
Zheng, J1
Guan, H1
Li, D2
Tan, H1
Maji, TK1
J R, A1
Mukherjee, S1
Alexander, R1
Mondal, A1
Das, S1
Sharma, RK1
Chakraborty, NK1
Dasgupta, K1
Sharma, AMR1
Hawaldar, R1
Pandey, M1
Naik, A1
Majumdar, K1
Pal, SK1
Adarsh, KV1
Ray, SK1
Karmakar, D1
Ma, Y2
Gao, W1
Ma, S1
Lin, W1
Zhou, T1
Wu, T1
Wu, Q1
Ye, C1
He, X1
Jiang, F1
Yuan, D1
Chen, Q2
Hong, M1
Chen, K1
Hussain, M1
Razi, SS1
Yildiz, EA1
Zhao, J1
Yaglioglu, HG1
Donato, MD1
Jiang, J1
Jamil, MI1
Zhan, X1
Chen, F1
Cheng, D1
Wu, CT1
Utsunomiya, T1
Ichii, T1
Fujinami, S1
Nakajima, K1
Sanchez, DM1
Raucci, U1
Ferreras, KN1
Martínez, TJ1
Mordi, NA1
Mordi, IR1
Singh, JS1
McCrimmon, RJ1
Struthers, AD1
Lang, CC1
Wang, XW1
Yuan, LJ1
Yang, Y1
Chen, WF1
Luo, R1
Yang, K1
Amarasiri, SS1
Attanayake, AP1
Arawwawala, LDAM1
Jayatilaka, KAPW1
Mudduwa, LKB1
Ogunsuyi, O2
Akanni, O1
Alabi, O1
Alimba, C1
Adaramoye, O1
Cambier, S1
Eswara, S1
Gutleb, AC1
Bakare, A1
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Gu, L1
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Reviews

13 reviews available for benzene and Genetic Predisposition

ArticleYear
Genomics of Detoxification: How Genomics can be Used for Targeting Potential Intervention and Prevention Strategies Including Nutrition for Environmentally Acquired Illness.
    Journal of the American College of Nutrition, 2020, Volume: 39, Issue:2

    Topics: Benzene; Chemically-Induced Disorders; Cytochrome P-450 Enzyme System; Environmental Exposure; Envir

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Key Genetic and Epigenetic Mechanisms in Chemical Carcinogenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 148, Issue:1

    Topics: Animals; Benzene; Biomarkers; Carcinogenesis; Carcinogens; Carcinogens, Environmental; DNA Methylati

2015
Biomarkers of susceptibility following benzene exposure: influence of genetic polymorphisms on benzene metabolism and health effects.
    Biomarkers in medicine, 2016, Volume: 10, Issue:2

    Topics: Acetylcysteine; Adult; Benzene; Biomarkers; Biotransformation; Carcinogenesis; Child; Cytochrome P-4

2016
Application of OMICS technologies in occupational and environmental health research; current status and projections.
    Occupational and environmental medicine, 2010, Volume: 67, Issue:2

    Topics: Arsenic; Benzene; Biomarkers; Environmental Medicine; Genetic Predisposition to Disease; Genomics; H

2010
[Individual susceptibility to hematotoxicity from benzene exposure and the genetic polymorphism of metabolic enzymes].
    Wei sheng yan jiu = Journal of hygiene research, 2002, Volume: 31, Issue:2

    Topics: Air Pollutants, Occupational; Benzene; Cytochrome P-450 CYP2E1; Genetic Predisposition to Disease; G

2002
[Risk of leukemia related with benzene and chromosomal aberrations.].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2005, Volume: 23, Issue:1

    Topics: Benzene; Carcinogens; Chromosome Aberrations; Genetic Predisposition to Disease; Humans; Leukemia

2005
Use of 'Omic' technologies to study humans exposed to benzene.
    Chemico-biological interactions, 2005, May-30, Volume: 153-154

    Topics: Air Pollutants, Occupational; Benzene; Biomarkers; Environmental Monitoring; Gene Expression Profili

2005
Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity.
    Chemico-biological interactions, 2005, May-30, Volume: 153-154

    Topics: Animals; Benzene; Bone Marrow; Genetic Predisposition to Disease; Humans; Hyperplasia; Leukemia; Mic

2005
Functions and distribution of NQO1 in human bone marrow: potential clues to benzene toxicity.
    Chemico-biological interactions, 2005, May-30, Volume: 153-154

    Topics: Animals; Benzene; Bone Marrow; Genetic Predisposition to Disease; Genotype; Humans; Leukemia; NAD(P)

2005
Benzene, NQO1, and genetic susceptibility to cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jul-06, Volume: 96, Issue:14

    Topics: Benzene; Genetic Predisposition to Disease; Homozygote; Humans; NAD(P)H Dehydrogenase (Quinone); Neo

1999
Recent developments in the understanding of benzene toxicity and leukemogenesis.
    Drug and chemical toxicology, 2000, Volume: 23, Issue:1

    Topics: Animals; Benzene; Bone Marrow; DNA; DNA Adducts; Dose-Response Relationship, Drug; Genetic Predispos

2000
Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen.
    Free radical biology & medicine, 2000, Volume: 29, Issue:3-4

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzene; Carcinogens; Drug Evaluation, Preclinical;

2000

Trials

2 trials available for benzene and Genetic Predisposition

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Genetic variations in benzene metabolism and susceptibility to multiple myeloma.
    Leukemia research, 2007, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzene; Case-Control Studies; Epoxide Hydrolases; Femal

2007

Other Studies

47 other studies available for benzene and Genetic Predisposition

ArticleYear
Genetic variations in ATM and H2AX loci contribute to risk of hematological abnormalities in individuals exposed to BTEX chemicals.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:4

    Topics: Ataxia Telangiectasia Mutated Proteins; Benzene; Benzene Derivatives; Genetic Predisposition to Dise

2022
Conditions of Aerogenic Exposure to Benzene and Genetic Status as Factors of Formation of Immune Profile Features in Men with Autonomic Regulation Disturbances.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:2

    Topics: Adult; Air Pollutants; Autonomic Nervous System; Autonomic Nervous System Diseases; Benzene; Case-Co

2021
Association Between Polymorphisms of Metabolic Enzyme Genes and Chromosomal Damage in Benzene-Exposed Workers in China.
    Journal of occupational and environmental medicine, 2017, Volume: 59, Issue:11

    Topics: Adult; Age Factors; Air Pollutants, Occupational; Benzene; China; Cytochrome P-450 CYP2E1; DNA Damag

2017
Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity.
    Archives of toxicology, 2018, Volume: 92, Issue:6

    Topics: Adult; Air Pollutants, Occupational; Benzene; Cross-Sectional Studies; Cytochrome P450 Family 2; Ery

2018
Effects of Genetic Polymorphism on Susceptibility to Nephrotoxic Properties of BTEXs Compounds.
    Journal of occupational and environmental medicine, 2018, Volume: 60, Issue:8

    Topics: Adult; Air Pollutants, Occupational; Benzene; Benzene Derivatives; Blood Urea Nitrogen; Chemical Ind

2018
Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers.
    Environmental and molecular mutagenesis, 2013, Volume: 54, Issue:6

    Topics: Benzene; China; Cytochrome P-450 CYP1A1; DNA Helicases; DNA Methylation; DNA-Binding Proteins; Envir

2013
New mouse models mimic biology of human cancer.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:2

    Topics: Air Pollutants; Animals; Animals, Inbred Strains; Animals, Outbred Strains; Benzene; Carcinogens; En

2015
[Analysis of cytochrome P450 2E1 RsaI/PstI and DraI polymorphisms in workers exposed to benzene].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2015, Volume: 33, Issue:8

    Topics: Alleles; Benzene; Cross-Sectional Studies; Cytochrome P-450 CYP2E1; Genetic Predisposition to Diseas

2015
Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Adolescent; Adult; Benzene; Case-Control Studies; China; DNA Helicases; DNA-Binding Proteins; Female

2015
Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population.
    Carcinogenesis, 2008, Volume: 29, Issue:12

    Topics: Adolescent; Adult; Alcohol Drinking; Asian People; Benzene; Case-Control Studies; Chronic Disease; E

2008
Genetic susceptibility to benzene toxicity in humans.
    Journal of toxicology and environmental health. Part A, 2008, Volume: 71, Issue:22

    Topics: Adult; Benzene; Bulgaria; Chemical Industry; DNA Damage; Female; Gene Expression Profiling; Genetic

2008
Association of genetic polymorphisms, mRNA expression of p53 and p21 with chronic benzene poisoning in a chinese occupational population.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Asian People; Benzene; Case-Control Studies; Chronic Disease; Cyclin-Dependent Ki

2009
Association of genetic polymorphisms in GADD45A, MDM2, and p14 ARF with the risk of chronic benzene poisoning in a Chinese occupational population.
    Toxicology and applied pharmacology, 2009, Oct-01, Volume: 240, Issue:1

    Topics: Adolescent; Adult; Aged; Asian People; Benzene; Case-Control Studies; Cell Cycle Proteins; Chronic D

2009
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
    Occupational and environmental medicine, 2009, Volume: 66, Issue:12

    Topics: Benzene; DNA Helicases; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Hematologic

2009
Peripheral blood effects in benzene-exposed workers.
    Chemico-biological interactions, 2010, Mar-19, Volume: 184, Issue:1-2

    Topics: Adult; Benzene; Blood Cells; DNA; Female; Genetic Predisposition to Disease; Hematologic Tests; Huma

2010
Polymorphisms in genes involved in innate immunity and susceptibility to benzene-induced hematotoxicity.
    Experimental & molecular medicine, 2011, Jun-30, Volume: 43, Issue:6

    Topics: Adult; Arachidonate 5-Lipoxygenase; Benzene; Cell Count; Cross-Sectional Studies; Female; Genetic As

2011
[The study of susceptibility to carbon tetrachloride and benzene in offspring of expanded simple tandem repeats mutation mice exposed to formaldehyde].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:5

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzene; Carbon Tetrachloride; Chemical

2011
Maternal smoking during pregnancy, genetic polymorphisms of metabolic enzymes, and childhood acute leukemia: the ESCALE study (SFCE).
    Cancer causes & control : CCC, 2012, Volume: 23, Issue:2

    Topics: Adolescent; Alleles; Benzene; Case-Control Studies; Child; Child, Preschool; Cytochrome P-450 CYP1A1

2012
[Association analysis of polymorphisms of metabolizing enzyme genes with chronic benzene poisoning based on logistic regression and multifactor dimensionality reduction].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:7

    Topics: Adult; Benzene; Case-Control Studies; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2D6; Cytochrome P

2011
Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
    Environmental health perspectives, 2002, Volume: 110, Issue:12

    Topics: Benzene; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; DNA Primers; Genetic Predisp

2002
Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1.
    Cancer research, 2003, Mar-01, Volume: 63, Issue:5

    Topics: Animals; Benzene; Bone Marrow Cells; Cytochrome P-450 CYP2E1; DNA; DNA Damage; Female; Genetic Predi

2003
Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 72, Issue:2

    Topics: Administration, Inhalation; Animals; Benzene; Bone Marrow Cells; Cyclin-Dependent Kinase Inhibitor p

2003
Urban benzene exposure and oxidative DNA damage: influence of genetic polymorphisms in metabolism genes.
    The Science of the total environment, 2003, Jun-20, Volume: 309, Issue:1-3

    Topics: Adult; Benzene; Biomarkers; Comet Assay; DNA Damage; Environmental Pollutants; Female; Genetic Predi

2003
Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 75, Issue:2

    Topics: Administration, Inhalation; Animals; Apoptosis; Benzene; Bone Marrow Cells; Cyclin-Dependent Kinase

2003
[Case-only study on the relationship between genetic polymorphisms in toxicant metabolizing enzymes and risk of occupational chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2004, Volume: 22, Issue:3

    Topics: Adult; Benzene; Cytochrome P-450 CYP2E1; Female; Genetic Predisposition to Disease; Genotype; Glutat

2004
[Relationship of genetic polymorphism of microsomal epoxide hydrolase with susceptibility of chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2004, Volume: 22, Issue:3

    Topics: Adult; Benzene; Case-Control Studies; Epoxide Hydrolases; Female; Genetic Predisposition to Disease;

2004
Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.
    Stem cells (Dayton, Ohio), 2004, Volume: 22, Issue:5

    Topics: Animals; Apoptosis; Benzene; Benzoquinones; Carcinogens; Cell Cycle Proteins; Cell Transformation, N

2004
A Rawlsian approach to solving the problem of genetic discrimination in toxic workplaces.
    The San Diego law review, 2002,Summer, Volume: 39, Issue:3

    Topics: Benzene; Compensation and Redress; Ethical Theory; Genetic Predisposition to Disease; Genetic Testin

2002
[Genetic polymorphisms of NQO1, GSTT1, GSTM1 and susceptibility to chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2005, Volume: 23, Issue:1

    Topics: Adult; Aged; Benzene; Case-Control Studies; Chronic Disease; Female; Genetic Predisposition to Disea

2005
[Genetic polymorphism of tumor necrosis factor-alpha in patients with chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2005, Volume: 23, Issue:3

    Topics: Adult; Benzene; Chronic Disease; Female; Genetic Predisposition to Disease; Genotype; Humans; Male;

2005
Genetic polymorphisms in XRCC1, APE1, ADPRT, XRCC2, and XRCC3 and risk of chronic benzene poisoning in a Chinese occupational population.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:11 Pt 1

    Topics: Adult; Benzene; China; Chronic Disease; DNA Damage; DNA Repair; Female; Genetic Predisposition to Di

2005
Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity.
    Carcinogenesis, 2006, Volume: 27, Issue:10

    Topics: Adult; Benzene; Blood Cells; Cross-Sectional Studies; DNA Helicases; DNA Repair; Exodeoxyribonucleas

2006
[Genetic polymorphism of CYP-1A1, CYP2D6 and risks of chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2006, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Benzene; Case-Control Studies; Chronic Disease; Cytochrome P-450 CYP1A1; Cytochro

2006
[Relationship of genetic polymorphism in APE1 and ADPRT to risks of chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2006, Volume: 24, Issue:7

    Topics: ADP Ribose Transferases; Alcohol Drinking; Benzene; Case-Control Studies; Chronic Disease; DNA-(Apur

2006
[Association between polymorphisms of XPD gene and susceptibility to chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2006, Volume: 24, Issue:7

    Topics: Alleles; Benzene; Case-Control Studies; Chronic Disease; Codon; Female; Genetic Predisposition to Di

2006
Genetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations.
    Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:1

    Topics: Adult; Aged; Asian People; Benzene; Case-Control Studies; China; Cytochrome P-450 CYP2E1; Female; Ge

2007
[Genetic polymorphisms of MPO, NQO1, GSTP1, UGT1A6 associated with susceptibility of chronic benzene poisoning].
    Wei sheng yan jiu = Journal of hygiene research, 2007, Volume: 36, Issue:1

    Topics: Adult; Alleles; Benzene; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype;

2007
Genetic polymorphisms in CYP1A1, CYP2D6, UGT1A6, UGT1A7, and SULT1A1 genes and correlation with benzene exposure in a Chinese occupational population.
    Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:11

    Topics: Adult; Arylsulfotransferase; Benzene; Case-Control Studies; China; Cytochrome P-450 CYP1A1; Cytochro

2007
[Association between genetic polymorphisms of DNA repair genes XRCC1, XRCC3 and susceptibility to chronic benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2007, Volume: 25, Issue:4

    Topics: Adult; Benzene; Case-Control Studies; Chronic Disease; DNA-Binding Proteins; Female; Genetic Predisp

2007
Association of the NQO1, MPO, and XRCC1 polymorphisms and chromosome damage among workers at a petroleum refinery.
    Journal of toxicology and environmental health. Part A, 2008, Volume: 71, Issue:5

    Topics: Adult; Benzene; Case-Control Studies; DNA Repair; DNA-Binding Proteins; Genetic Predisposition to Di

2008
[Relation between genetic polymorphism of hMSH2 and genetic predisposition of chronic occupational benzene poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2008, Volume: 26, Issue:2

    Topics: Adult; Benzene; Case-Control Studies; Chronic Disease; Female; Genetic Predisposition to Disease; Hu

2008
Benzene exposure, glutathione S-transferase theta homozygous deletion, and sister chromatid exchanges.
    American journal of industrial medicine, 1998, Volume: 33, Issue:2

    Topics: Adult; Benzene; Case-Control Studies; China; DNA Damage; Female; Gene Deletion; Genetic Predispositi

1998
Biomarkers of leukemia risk: benzene as a model.
    Environmental health perspectives, 1998, Volume: 106 Suppl 4

    Topics: Adult; Benzene; Biomarkers; Child; Chromosome Aberrations; Environmental Exposure; Genetic Predispos

1998
A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jul-06, Volume: 96, Issue:14

    Topics: Adult; Amino Acid Substitution; Antigens, CD34; Apoptosis; Benzene; Bone Marrow Cells; Catechols; En

1999
A cost-benefit analysis of genetic screening for susceptibility to occupational toxicants.
    Journal of occupational and environmental medicine, 1999, Volume: 41, Issue:7

    Topics: Benzene; Berylliosis; Cost-Benefit Analysis; Genetic Predisposition to Disease; Genetic Testing; Hum

1999
Genetic susceptibility to benzene and shortened gestation: evidence of gene-environment interaction.
    American journal of epidemiology, 2000, Oct-15, Volume: 152, Issue:8

    Topics: Adult; Benzene; China; Cytochrome P-450 Enzyme System; Environmental Exposure; Female; Genetic Predi

2000
Invited commentary: on studying the joint effects of candidate genes and exposures.
    American journal of epidemiology, 2000, Oct-15, Volume: 152, Issue:8

    Topics: Benzene; Confounding Factors, Epidemiologic; Cytochrome P-450 CYP1A1; Environmental Exposure; Female

2000