benzene has been researched along with Experimental Leukemia in 23 studies
Excerpt | Relevance | Reference |
---|---|---|
"Although benzene is best known as a compound that causes bone marrow depression leading to aplastic anemia in animals and humans, it also induces acute myelogenous leukemia in humans." | 4.79 | A perspective on benzene leukemogenesis. ( Kalf, GF; Snyder, R, 1994) |
"Until recently, the incidence of benzene carcinogenicity was based only on the association between benzene occupational exposure and human leukemia, with many limited case reports and scanty epidemiological data." | 3.66 | Benzene: a multipotential carcinogen. Results of long-term bioassays performed at the Bologna Institute of Oncology. ( Conti, B; Cotti, G; Maltoni, C, 1983) |
" We thus hypothesize that free radicals contribute, at least in part, to the toxic and leukemogenic effects of benzene." | 2.38 | Potential role of free radicals in benzene-induced myelotoxicity and leukemia. ( Eastmond, DA; Ross, D; Smith, MT; Subrahmanyam, VV, 1991) |
"There was one case of chronic myelogenous leukemia, one of acute myeloblastic leukemia, and one of granulocytic hyperplasia among 40 CD-1 mice exposed to 300 ppm benzene; and one case of chronic myelogenous leukemia among 40 rats exposed to 100 ppm benzene." | 1.26 | Myelogenous leukemia in rodents inhaling benzene. ( Albert, RE; Bromberg, I; Goldstein, BD; Laskin, S; Nelson, N; Snyder, CA, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 15 (65.22) | 18.7374 |
1990's | 6 (26.09) | 18.2507 |
2000's | 2 (8.70) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
KIRSCHBAUM, A | 1 |
JUDD, T | 1 |
KHOKHLOVA, MP | 1 |
AMIEL, JL | 1 |
Burlakova, EB | 1 |
Pal'mina, NP | 1 |
Maltoni, C | 1 |
Conti, B | 1 |
Cotti, G | 1 |
Cronkite, EP | 5 |
Bullis, J | 1 |
Inoue, T | 2 |
Drew, RT | 2 |
Goldstein, BD | 1 |
Snyder, CA | 1 |
Laskin, S | 1 |
Bromberg, I | 1 |
Albert, RE | 1 |
Nelson, N | 1 |
Snyder, R | 2 |
Kalf, GF | 1 |
Irons, RD | 1 |
Stillman, WS | 1 |
Smith, MT | 2 |
Fanning, EW | 1 |
Rithidech, K | 1 |
Dunn, JJ | 1 |
Bond, VP | 1 |
Gordon, CR | 1 |
French, JE | 1 |
Saulnier, M | 1 |
Tabershaw, IR | 1 |
Subrahmanyam, VV | 1 |
Ross, D | 1 |
Eastmond, DA | 1 |
Ellis, NM | 1 |
Pellack-Walker, P | 1 |
Blumer, JL | 1 |
Sokolov, VV | 1 |
Frash, VN | 1 |
Bullis, JE | 1 |
Gunz, FW | 1 |
Laerum, OD | 1 |
7 reviews available for benzene and Experimental Leukemia
Article | Year |
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A perspective on benzene leukemogenesis.
Topics: Animals; Benzene; Benzene Derivatives; Carcinogens; Humans; Leukemia; Leukemia, Experimental | 1994 |
The effects of benzene and other leukaemogenic agents on haematopoietic stem and progenitor cell differentiation.
Topics: Animals; Benzene; Carcinogens; Cell Differentiation; Cytokines; Hematopoietic Stem Cells; Humans; Le | 1996 |
Characterization of genetic instability in radiation- and benzene-induced murine acute leukemia.
Topics: Animals; Benzene; Chromosome Banding; Chromosome Deletion; Disease Models, Animal; Humans; In Situ H | 1999 |
Recent developments in the understanding of benzene toxicity and leukemogenesis.
Topics: Animals; Benzene; Bone Marrow; DNA; DNA Adducts; Dose-Response Relationship, Drug; Genetic Predispos | 2000 |
Potential role of free radicals in benzene-induced myelotoxicity and leukemia.
Topics: Animals; Benzene; Bone Marrow; Free Radicals; Humans; Leukemia, Experimental | 1991 |
Chemical leukemogenesis: benzene as a model.
Topics: Animals; Benzene; Disease Models, Animal; Hematopoiesis; Humans; Leukemia; Leukemia, Experimental; M | 1987 |
[Debatable questions of the leukemogenic (blastomogenic) action of benzine].
Topics: Animals; Benzene; Chromosome Aberrations; DNA; Dose-Response Relationship, Drug; Humans; Immune Tole | 1985 |
16 other studies available for benzene and Experimental Leukemia
Article | Year |
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Effect of urethane, X-rays, potassium arsenite, benzol, on survival time in transplanted mouse leukemia.
Topics: Animals; Arsenicals; Arsenites; Benzene; Leukemia; Leukemia, Experimental; Potassium; Potassium Comp | 1948 |
Pathologic anatomy of experimental leukemia produced by injection of benzol extracts from organs of leukemic patients.
Topics: Animals; Benzene; Humans; Injections; Leukemia, Experimental | 1958 |
[Negative attempt at induction of leukemia in mice by benzene].
Topics: Animals; Benzene; Leukemia; Leukemia, Experimental; Mice | 1960 |
[Synthetic inhibitors and natural antioxidants. 3. The antioxidative activity of lipids of mouse liver in transplanted leukosis and the action of free radical reaction inhibitors].
Topics: Animals; Antioxidants; Benzene; Chemistry, Organic; Free Radicals; Leukemia, Experimental; Leukocyte | 1966 |
Benzene: a multipotential carcinogen. Results of long-term bioassays performed at the Bologna Institute of Oncology.
Topics: Animals; Benzene; Bone Marrow; Cricetinae; Drug Evaluation, Preclinical; Female; History, 20th Centu | 1983 |
Benzene inhalation produces leukemia in mice.
Topics: Animals; Atmosphere Exposure Chambers; Benzene; Female; Leukemia, Experimental; Lymphoma; Mice; Mice | 1984 |
Myelogenous leukemia in rodents inhaling benzene.
Topics: Animals; Benzene; Carcinogens; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute; | 1982 |
Report on the workshop entitled: "Modeling chemically induced leukemia--implications for benzene risk assessment".
Topics: Animals; Benzene; Biotransformation; Carcinogens; Hematopoietic Stem Cells; Humans; Leukemia; Leukem | 1997 |
Benzene leukemogenesis: an environmental carcinogen-induced tissue-specific model of neoplasia using genetically altered mouse models.
Topics: Animals; Benzene; Carcinogens, Environmental; Disease Models, Animal; Female; Leukemia, Experimental | 2000 |
Protection from adverse effects of benzene.
Topics: Animals; Benzene; Carcinogens, Environmental; Government Agencies; Humans; Leukemia; Leukemia, Exper | 1978 |
Chemical carcinogenesis--toluene?
Topics: Acute Disease; Animals; Benzene; Humans; Leukemia, Experimental; Toluene | 1991 |
DNA damage in L5178YS cells following exposure to benzene metabolites.
Topics: Animals; Benzene; Benzoquinones; Catechols; DNA, Neoplasm; Dose-Response Relationship, Drug; Hydroqu | 1986 |
Benzene hematotoxicity and leukemogenesis.
Topics: Anemia; Animals; Benzene; Bone Marrow; Dose-Response Relationship, Drug; Female; Hematopoietic Stem | 1986 |
Benzene hematotoxicity and leukemogenesis.
Topics: Animals; Benzene; Female; Granulocytes; Hematopoietic Stem Cells; Leukemia, Experimental; Lymphocyte | 1985 |
Problems in leukemia etiology.
Topics: Animals; Benzene; Diseases in Twins; Down Syndrome; Fanconi Syndrome; Humans; Leukemia; Leukemia Vir | 1970 |
Reticulum cell neoplasms in normal and benzene treated hairless mice.
Topics: Age Factors; Animals; Benzene; Carcinogens; Female; Hair; Leukemia, Experimental; Lymphoma, Follicul | 1973 |