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benzene and Experimental Leukemia

benzene has been researched along with Experimental Leukemia in 23 studies

Research Excerpts

ExcerptRelevanceReference
"Although benzene is best known as a compound that causes bone marrow depression leading to aplastic anemia in animals and humans, it also induces acute myelogenous leukemia in humans."4.79A perspective on benzene leukemogenesis. ( Kalf, GF; Snyder, R, 1994)
"Until recently, the incidence of benzene carcinogenicity was based only on the association between benzene occupational exposure and human leukemia, with many limited case reports and scanty epidemiological data."3.66Benzene: a multipotential carcinogen. Results of long-term bioassays performed at the Bologna Institute of Oncology. ( Conti, B; Cotti, G; Maltoni, C, 1983)
" We thus hypothesize that free radicals contribute, at least in part, to the toxic and leukemogenic effects of benzene."2.38Potential role of free radicals in benzene-induced myelotoxicity and leukemia. ( Eastmond, DA; Ross, D; Smith, MT; Subrahmanyam, VV, 1991)
"There was one case of chronic myelogenous leukemia, one of acute myeloblastic leukemia, and one of granulocytic hyperplasia among 40 CD-1 mice exposed to 300 ppm benzene; and one case of chronic myelogenous leukemia among 40 rats exposed to 100 ppm benzene."1.26Myelogenous leukemia in rodents inhaling benzene. ( Albert, RE; Bromberg, I; Goldstein, BD; Laskin, S; Nelson, N; Snyder, CA, 1982)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199015 (65.22)18.7374
1990's6 (26.09)18.2507
2000's2 (8.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KIRSCHBAUM, A1
JUDD, T1
KHOKHLOVA, MP1
AMIEL, JL1
Burlakova, EB1
Pal'mina, NP1
Maltoni, C1
Conti, B1
Cotti, G1
Cronkite, EP5
Bullis, J1
Inoue, T2
Drew, RT2
Goldstein, BD1
Snyder, CA1
Laskin, S1
Bromberg, I1
Albert, RE1
Nelson, N1
Snyder, R2
Kalf, GF1
Irons, RD1
Stillman, WS1
Smith, MT2
Fanning, EW1
Rithidech, K1
Dunn, JJ1
Bond, VP1
Gordon, CR1
French, JE1
Saulnier, M1
Tabershaw, IR1
Subrahmanyam, VV1
Ross, D1
Eastmond, DA1
Ellis, NM1
Pellack-Walker, P1
Blumer, JL1
Sokolov, VV1
Frash, VN1
Bullis, JE1
Gunz, FW1
Laerum, OD1

Reviews

7 reviews available for benzene and Experimental Leukemia

ArticleYear
A perspective on benzene leukemogenesis.
    Critical reviews in toxicology, 1994, Volume: 24, Issue:3

    Topics: Animals; Benzene; Benzene Derivatives; Carcinogens; Humans; Leukemia; Leukemia, Experimental

1994
The effects of benzene and other leukaemogenic agents on haematopoietic stem and progenitor cell differentiation.
    European journal of haematology. Supplementum, 1996, Volume: 60

    Topics: Animals; Benzene; Carcinogens; Cell Differentiation; Cytokines; Hematopoietic Stem Cells; Humans; Le

1996
Characterization of genetic instability in radiation- and benzene-induced murine acute leukemia.
    Mutation research, 1999, Jul-16, Volume: 428, Issue:1-2

    Topics: Animals; Benzene; Chromosome Banding; Chromosome Deletion; Disease Models, Animal; Humans; In Situ H

1999
Recent developments in the understanding of benzene toxicity and leukemogenesis.
    Drug and chemical toxicology, 2000, Volume: 23, Issue:1

    Topics: Animals; Benzene; Bone Marrow; DNA; DNA Adducts; Dose-Response Relationship, Drug; Genetic Predispos

2000
Potential role of free radicals in benzene-induced myelotoxicity and leukemia.
    Free radical biology & medicine, 1991, Volume: 11, Issue:5

    Topics: Animals; Benzene; Bone Marrow; Free Radicals; Humans; Leukemia, Experimental

1991
Chemical leukemogenesis: benzene as a model.
    Seminars in hematology, 1987, Volume: 24, Issue:1

    Topics: Animals; Benzene; Disease Models, Animal; Hematopoiesis; Humans; Leukemia; Leukemia, Experimental; M

1987
[Debatable questions of the leukemogenic (blastomogenic) action of benzine].
    Gigiena truda i professional'nye zabolevaniia, 1985, Issue:4

    Topics: Animals; Benzene; Chromosome Aberrations; DNA; Dose-Response Relationship, Drug; Humans; Immune Tole

1985

Other Studies

16 other studies available for benzene and Experimental Leukemia

ArticleYear
Effect of urethane, X-rays, potassium arsenite, benzol, on survival time in transplanted mouse leukemia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1948, Volume: 68, Issue:2

    Topics: Animals; Arsenicals; Arsenites; Benzene; Leukemia; Leukemia, Experimental; Potassium; Potassium Comp

1948
Pathologic anatomy of experimental leukemia produced by injection of benzol extracts from organs of leukemic patients.
    Blood, 1958, Volume: 13, Issue:10

    Topics: Animals; Benzene; Humans; Injections; Leukemia, Experimental

1958
[Negative attempt at induction of leukemia in mice by benzene].
    Revue francaise d'etudes cliniques et biologiques, 1960, Volume: 5

    Topics: Animals; Benzene; Leukemia; Leukemia, Experimental; Mice

1960
[Synthetic inhibitors and natural antioxidants. 3. The antioxidative activity of lipids of mouse liver in transplanted leukosis and the action of free radical reaction inhibitors].
    Biofizika, 1966, Volume: 11, Issue:2

    Topics: Animals; Antioxidants; Benzene; Chemistry, Organic; Free Radicals; Leukemia, Experimental; Leukocyte

1966
Benzene: a multipotential carcinogen. Results of long-term bioassays performed at the Bologna Institute of Oncology.
    American journal of industrial medicine, 1983, Volume: 4, Issue:5

    Topics: Animals; Benzene; Bone Marrow; Cricetinae; Drug Evaluation, Preclinical; Female; History, 20th Centu

1983
Benzene inhalation produces leukemia in mice.
    Toxicology and applied pharmacology, 1984, Sep-15, Volume: 75, Issue:2

    Topics: Animals; Atmosphere Exposure Chambers; Benzene; Female; Leukemia, Experimental; Lymphoma; Mice; Mice

1984
Myelogenous leukemia in rodents inhaling benzene.
    Toxicology letters, 1982, Volume: 13, Issue:3-4

    Topics: Animals; Benzene; Carcinogens; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute;

1982
Report on the workshop entitled: "Modeling chemically induced leukemia--implications for benzene risk assessment".
    Leukemia research, 1997, Volume: 21, Issue:5

    Topics: Animals; Benzene; Biotransformation; Carcinogens; Hematopoietic Stem Cells; Humans; Leukemia; Leukem

1997
Benzene leukemogenesis: an environmental carcinogen-induced tissue-specific model of neoplasia using genetically altered mouse models.
    Journal of toxicology and environmental health. Part A, 2000, Volume: 61, Issue:5-6

    Topics: Animals; Benzene; Carcinogens, Environmental; Disease Models, Animal; Female; Leukemia, Experimental

2000
Protection from adverse effects of benzene.
    Texas reports on biology and medicine, 1978, Volume: 37

    Topics: Animals; Benzene; Carcinogens, Environmental; Government Agencies; Humans; Leukemia; Leukemia, Exper

1978
Chemical carcinogenesis--toluene?
    The Medical journal of Australia, 1991, Aug-19, Volume: 155, Issue:4

    Topics: Acute Disease; Animals; Benzene; Humans; Leukemia, Experimental; Toluene

1991
DNA damage in L5178YS cells following exposure to benzene metabolites.
    Molecular pharmacology, 1986, Volume: 30, Issue:1

    Topics: Animals; Benzene; Benzoquinones; Catechols; DNA, Neoplasm; Dose-Response Relationship, Drug; Hydroqu

1986
Benzene hematotoxicity and leukemogenesis.
    Blood cells, 1986, Volume: 12, Issue:1

    Topics: Anemia; Animals; Benzene; Bone Marrow; Dose-Response Relationship, Drug; Female; Hematopoietic Stem

1986
Benzene hematotoxicity and leukemogenesis.
    American journal of industrial medicine, 1985, Volume: 7, Issue:5-6

    Topics: Animals; Benzene; Female; Granulocytes; Hematopoietic Stem Cells; Leukemia, Experimental; Lymphocyte

1985
Problems in leukemia etiology.
    Hamatologie und Bluttransfusion, 1970, Volume: 9

    Topics: Animals; Benzene; Diseases in Twins; Down Syndrome; Fanconi Syndrome; Humans; Leukemia; Leukemia Vir

1970
Reticulum cell neoplasms in normal and benzene treated hairless mice.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1973, Volume: 81, Issue:1

    Topics: Age Factors; Animals; Benzene; Carcinogens; Female; Hair; Leukemia, Experimental; Lymphoma, Follicul

1973