benzene has been researched along with Chromosome Deletion in 12 studies
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidemiological studies show that benzene exposure is associated with an increased incidence of leukemia and perhaps lymphoma." | 7.74 | Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Li, G; Lu, W; Rothman, N; Smith, MT; Yang, W; Yin, S; Zhang, L, 2007) |
| " Over the last half-century a predominant paradigm has emerged to describe leukemia developing secondary to alkylating drug therapy or exposure to benzene in which progressive dysplastic changes, accompanied by a distinct pattern of clonal cytogenetic abnormalities, give rise to acute myelogenous leukemia." | 4.79 | The process of leukemogenesis. ( Irons, RD; Stillman, WS, 1996) |
| "Epidemiological studies show that benzene exposure is associated with an increased incidence of leukemia and perhaps lymphoma." | 3.74 | Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Li, G; Lu, W; Rothman, N; Smith, MT; Yang, W; Yin, S; Zhang, L, 2007) |
| "Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML)." | 3.70 | The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 1999) |
| "Benzene exposure causes acute myeloid leukemia and hematotoxicity, shown as suppression of mature blood and myeloid progenitor cell numbers." | 1.38 | Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Ji, Z; Lan, Q; Li, G; Linet, MS; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2012) |
| "Benzene exposure was associated with increases in the rates of monosomy 5 and 7 but not monosomy 1 (P < 0." | 1.30 | Increased aneusomy and long arm deletion of chromosomes 5 and 7 in the lymphocytes of Chinese workers exposed to benzene. ( Dosemeci, M; Hayes, RB; Kolachana, P; Li, G; Rothman, N; Smith, MT; Titenko-Holland, N; Wang, Y; Yin, S; Zhang, L, 1998) |
| "Benzene is a widely recognized human and animal carcinogen." | 1.29 | Chromosomal loss and breakage in mouse bone marrow and spleen cells exposed to benzene in vivo. ( Chen, H; Eastmond, DA; Rupa, DS; Tomar, R, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soós, I | 1 |
| Szabad, J | 1 |
| Zhang, L | 4 |
| Lan, Q | 1 |
| Ji, Z | 1 |
| Li, G | 3 |
| Shen, M | 1 |
| Vermeulen, R | 1 |
| Guo, W | 2 |
| Hubbard, AE | 3 |
| McHale, CM | 1 |
| Rappaport, SM | 1 |
| Hayes, RB | 3 |
| Linet, MS | 1 |
| Yin, S | 3 |
| Smith, MT | 4 |
| Rothman, N | 3 |
| Yang, W | 2 |
| Lu, W | 1 |
| Carls, N | 1 |
| Schiestl, RH | 1 |
| Chen, H | 1 |
| Rupa, DS | 1 |
| Tomar, R | 1 |
| Eastmond, DA | 1 |
| Irons, RD | 2 |
| Stillman, WS | 2 |
| Carere, A | 1 |
| Antoccia, A | 1 |
| Cimini, D | 1 |
| Crebelli, R | 1 |
| Degrassi, F | 1 |
| Leopardi, P | 1 |
| Marcon, F | 1 |
| Sgura, A | 1 |
| Tanzarella, C | 1 |
| Zijno, A | 1 |
| Wang, Y | 1 |
| Dosemeci, M | 1 |
| Kolachana, P | 1 |
| Titenko-Holland, N | 1 |
| Rithidech, K | 1 |
| Dunn, JJ | 1 |
| Bond, VP | 1 |
| Gordon, CR | 1 |
| Cronkite, EP | 1 |
| Varella-Garcia, M | 1 |
| Lumley, M | 1 |
| Barker, H | 1 |
| Murray, JA | 1 |
2 reviews available for benzene and Chromosome Deletion
| Article | Year |
|---|---|
The process of leukemogenesis.
Topics: Benzene; Carcinogens; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 5; Cocar | 1996 |
Characterization of genetic instability in radiation- and benzene-induced murine acute leukemia.
Topics: Animals; Benzene; Chromosome Banding; Chromosome Deletion; Disease Models, Animal; Humans; In Situ H | 1999 |
10 other studies available for benzene and Chromosome Deletion
| Article | Year |
|---|---|
Assaying benzene, a parquet varnish, and a synthetic thinner with respect to induction of in vivo chromosome loss in wing primordial cells of Drosophila.
Topics: Animals; Animals, Genetically Modified; Benzene; Chromosome Deletion; Drosophila; Drosophila Protein | 2014 |
Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers.
Topics: Adult; Aneuploidy; Benzene; Case-Control Studies; Chromosome Deletion; Chromosomes, Human, Pair 7; C | 2012 |
Nonrandom aneuploidy of chromosomes 1, 5, 6, 7, 8, 9, 11, 12, and 21 induced by the benzene metabolites hydroquinone and benzenetriol.
Topics: Acute Disease; Benzene; Cells, Cultured; Chromosome Deletion; Chromosomes, Human; Female; Humans; Hy | 2005 |
Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers.
Topics: Adult; Benzene; Case-Control Studies; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Huma | 2007 |
Evaluation of the yeast DEL assay with 10 compounds selected by the International Program on Chemical Safety for the evaluation of short-term tests for carcinogens.
Topics: Acrylonitrile; Benzene; Carcinogens; Chromosome Deletion; Diethylhexyl Phthalate; Diethylstilbestrol | 1994 |
Chromosomal loss and breakage in mouse bone marrow and spleen cells exposed to benzene in vivo.
Topics: Aneuploidy; Animals; Antibodies; Base Sequence; Benzene; Bone Marrow Cells; Chromosome Aberrations; | 1994 |
Genetic effects of petroleum fuels: II. Analysis of chromosome loss and hyperploidy in peripheral lymphocytes of gasoline station attendants.
Topics: Air Pollutants, Occupational; Aneuploidy; Benzene; Cell Cycle; Cells, Cultured; Chromosome Deletion; | 1998 |
Increased aneusomy and long arm deletion of chromosomes 5 and 7 in the lymphocytes of Chinese workers exposed to benzene.
Topics: Adult; Benzene; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 5; Chromos | 1998 |
The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line.
Topics: Benzene; Catechols; Cell Transformation, Neoplastic; Chromosome Deletion; Chromosomes, Human, Pair 5 | 1999 |
Benzene in petrol.
Topics: Benzene; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair | 1990 |