benzene has been researched along with Chromosome-Defective Micronuclei in 31 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzene is a well-known carcinogen that induces chromosomal instability, including chromosome aberration and aneuploidy." | 3.76 | Micronucleus-centromere assay in workers occupationally exposed to low level of benzene. ( , 2010) |
| "It has been shown, that benzene causes chromosomal aberrations, sister chromatid exchanges and micronuclei in lymphocytes of exposed workers." | 2.42 | Chromosomal aberrations in humans induced by benzene. ( Dianovskỳ, J; Holecková, B; Piesová, E; Sivikova, K, 2004) |
| "Benzene is a ubiquitous environmental pollutant and a confirmed human carcinogen, which requires metabolic activation, primarily by CYP2E1, for most of its biological actions." | 1.40 | Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster V79-derived cells. ( Hu, K; Jiang, H; Lai, Y; Liu, Y; Wei, Q, 2014) |
| "Benzene is a leukemogen, and exposure to benzene is an occupational hazard in the petroleum refining industries." | 1.35 | Association of the NQO1, MPO, and XRCC1 polymorphisms and chromosome damage among workers at a petroleum refinery. ( Choi, JY; Chung, HW; Kim, YJ; Paek, D, 2008) |
| "Benzene is an important industrial chemical." | 1.35 | Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice. ( Allison, N; Bird, MG; Dorman, DC; Gao, P; Letinski, DJ; Nicolich, MJ; Roberts, KC; Sharma, S; Struve, MF; Wetmore, BA, 2008) |
| " Here we compared the toxic effects of benzene on mice (C57BL/6 and 129/Sv) homozygous for the wild-type Prkdc allele and mice (129/SvJ) homozygous for a Prkdc functional polymorphism that leads to diminished DNA-PK activity and enhanced apoptosis in response to radiation-induced damage." | 1.32 | Variations in Prkdc and susceptibility to benzene-induced toxicity in mice. ( Abernethy, DJ; Bauer, AK; Everitt, JI; Faiola, B; Fuller, ES; Mangum, JB; Pluta, LJ; Recio, L; Wong, VA, 2003) |
| "Benzene is a widespread human carcinogen, inducing leukaemia and hematotoxicity." | 1.32 | The induction of micronuclei in bovine lymphocytes by exposure to benzene and S-9 mix. ( Piesova, E; Sivikova, K, 2003) |
| " Since P-450 catalyzed oxidation of benzene is crucial to its toxic effects, the action of DAMC and related analogues were considered promising in preventing the genotoxicity due to benzene." | 1.31 | Chemoprevention of benzene-induced bone marrow and pulmonary genotoxicity. ( Adhikari, JS; Bose, M; Dwarakanath, BS; Jain, SC; Kohli, E; Malik, S; Olsen, CE; Parmar, VS; Raj, HG; Rohil, V; Tyagi, YK, 2001) |
| "Benzene is an established human leukemogen." | 1.28 | Characterization of micronuclei induced in human lymphocytes by benzene metabolites. ( Eastmond, DA; Paradisin, WM; Robertson, ML; Smith, MT; Yager, JW, 1990) |
| " These findings bring further support to the hypothesis that the toxic and genotoxic effects of benzene are produced by several metabolites acting synergistically." | 1.28 | Genotoxicity of two metabolites of benzene: phenol and hydroquinone show strong synergistic effects in vivo. ( Barale, R; Barrai, I; Betti, C; Loprieno, N; Marrazzini, A; Vangelisti, V, 1990) |
| "Benzene pretreatment also had no effect, in either species, on formation of [14C]benzene-derived hemoglobin adducts." | 1.28 | Effect of repeated benzene inhalation exposures on benzene metabolism, binding to hemoglobin, and induction of micronuclei. ( Birnbaum, LS; Henderson, RF; Lucier, G; MacGregor, JT; Sabourin, PJ; Sun, JD; Wehr, CM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (35.48) | 18.2507 |
| 2000's | 9 (29.03) | 29.6817 |
| 2010's | 11 (35.48) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sha, Y | 1 |
| Zhou, W | 1 |
| Yang, Z | 1 |
| Zhu, X | 1 |
| Xiang, Y | 1 |
| Li, T | 1 |
| Zhu, D | 1 |
| Yang, X | 1 |
| Jiang, H | 1 |
| Lai, Y | 1 |
| Hu, K | 1 |
| Wei, Q | 1 |
| Liu, Y | 1 |
| Jamebozorgi, I | 1 |
| Mahjoubi, F | 1 |
| Pouryaghoub, G | 1 |
| Mehrdad, R | 1 |
| Majidzadeh, T | 1 |
| Saltanatpour, Z | 1 |
| Nasiri, F | 1 |
| Lau, A | 1 |
| Belanger, CL | 1 |
| Winn, LM | 1 |
| Bird, MG | 2 |
| Wetmore, BA | 2 |
| Letinski, DJ | 2 |
| Nicolich, M | 1 |
| Chen, M | 1 |
| Schnatter, AR | 1 |
| Whitman, FT | 1 |
| Rekhadevi, PV | 1 |
| Mahboob, M | 1 |
| Rahman, MF | 1 |
| Grover, P | 1 |
| Angelini, S | 2 |
| Kumar, R | 1 |
| Bermejo, JL | 2 |
| Maffei, F | 2 |
| Barbieri, A | 1 |
| Graziosi, F | 1 |
| Carbone, F | 1 |
| Cantelli-Forti, G | 2 |
| Violante, FS | 2 |
| Hemminki, K | 1 |
| Hrelia, P | 2 |
| Kumar, A | 1 |
| Sushama, A | 1 |
| Rohil, V | 2 |
| Manral, S | 1 |
| Gangopadhyay, S | 1 |
| Prasad, AK | 1 |
| Raj, HG | 2 |
| Parmar, VS | 2 |
| Rossnerova, A | 1 |
| Spatova, M | 1 |
| Pastorkova, A | 1 |
| Tabashidze, N | 1 |
| Veleminsky, M | 1 |
| Balascak, I | 1 |
| Solansky, I | 1 |
| Sram, RJ | 1 |
| Ravegnini, G | 1 |
| L'insalata, D | 1 |
| Zhang, J | 1 |
| Lü, JP | 1 |
| Zhang, C | 1 |
| Zhou, LF | 1 |
| Ye, YJ | 1 |
| Sun, P | 1 |
| Cheng, ZX | 1 |
| Xia, ZL | 1 |
| Faiola, B | 1 |
| Bauer, AK | 1 |
| Fuller, ES | 1 |
| Wong, VA | 1 |
| Pluta, LJ | 2 |
| Abernethy, DJ | 1 |
| Mangum, JB | 1 |
| Everitt, JI | 1 |
| Recio, L | 2 |
| Piesova, E | 2 |
| Sivikova, K | 2 |
| Ye, LL | 1 |
| Zhu, MY | 1 |
| Ye, HK | 1 |
| Wu, JB | 1 |
| Lin, Z | 1 |
| Zhang, SH | 1 |
| Jiang, L | 1 |
| Chen, P | 1 |
| Hu, LM | 1 |
| Holecková, B | 1 |
| Dianovskỳ, J | 1 |
| Kim, YJ | 1 |
| Choi, JY | 1 |
| Paek, D | 1 |
| Chung, HW | 1 |
| Struve, MF | 1 |
| Gao, P | 1 |
| Sharma, S | 1 |
| Allison, N | 1 |
| Roberts, KC | 1 |
| Nicolich, MJ | 1 |
| Dorman, DC | 1 |
| Marrazzini, A | 2 |
| Chelotti, L | 1 |
| Barrai, I | 2 |
| Loprieno, N | 2 |
| Barale, R | 2 |
| Chen, H | 1 |
| Eastmond, DA | 2 |
| Medinsky, MA | 1 |
| Schlosser, PM | 1 |
| Bond, JA | 1 |
| Pitarque, M | 1 |
| Carbonell, E | 1 |
| Lapeña, N | 1 |
| Marsá, M | 1 |
| Torres, M | 1 |
| Creus, A | 1 |
| Xamena, N | 1 |
| Marcos, R | 1 |
| Nilsson, R | 1 |
| Nordlinder, R | 1 |
| Högstedt, B | 2 |
| Karlsson, A | 1 |
| Järvholm, B | 1 |
| Mozdarani, H | 1 |
| Kamali, S | 1 |
| Malik, S | 1 |
| Kohli, E | 1 |
| Tyagi, YK | 1 |
| Dwarakanath, BS | 1 |
| Adhikari, JS | 1 |
| Bose, M | 1 |
| Jain, SC | 1 |
| Olsen, CE | 1 |
| Healy, LN | 1 |
| James, RA | 1 |
| Janszen, DB | 1 |
| Torous, D | 1 |
| French, JE | 1 |
| Nise, G | 1 |
| Bratt, I | 1 |
| Skerfving, S | 1 |
| Ning, H | 1 |
| Kado, NY | 1 |
| Kuzmicky, PA | 1 |
| Hsieh, DP | 1 |
| Yager, JW | 1 |
| Robertson, ML | 1 |
| Paradisin, WM | 1 |
| Smith, MT | 1 |
| Betti, C | 1 |
| Vangelisti, V | 1 |
| Sabourin, PJ | 1 |
| Sun, JD | 1 |
| MacGregor, JT | 1 |
| Wehr, CM | 1 |
| Birnbaum, LS | 1 |
| Lucier, G | 1 |
| Henderson, RF | 1 |
1 review available for benzene and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Chromosomal aberrations in humans induced by benzene.
Topics: Benzene; Chromosome Aberrations; Cytogenetic Analysis; DNA Damage; Humans; In Situ Hybridization, Fl | 2004 |
30 other studies available for benzene and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Changes in poly(ADP-ribosyl)ation patterns in workers exposed to BTX.
Topics: Adult; Benzene; Case-Control Studies; Cytokinesis; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytos | 2014 |
Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster V79-derived cells.
Topics: Animals; Arylsulfotransferase; Benzene; Benzene Derivatives; Catechols; Cell Line; Cricetinae; Crice | 2014 |
Micronucleus, Nucleoplasmic Bridge, and Nuclear Budding in Peripheral Blood Cells of Workers Exposed to Low Level Benzene.
Topics: Adult; Benzene; Case-Control Studies; Chemical Industry; DNA Damage; Humans; Lymphocytes; Male; Micr | 2016 |
In utero and acute exposure to benzene: investigation of DNA double-strand breaks and DNA recombination in mice.
Topics: Animals; Benzene; Bone Marrow; Bone Marrow Cells; Cell Nucleus; DNA; DNA Breaks, Double-Stranded; DN | 2009 |
Influence of toluene co-exposure on the metabolism and genotoxicity of benzene in mice using continuous and intermittent exposures.
Topics: Animals; Benzene; Bone Marrow; Buthionine Sulfoximine; Genes; Glutathione; Male; Mice; Micronuclei, | 2010 |
Micronucleus-centromere assay in workers occupationally exposed to low level of benzene.
Topics: Adult; Air Pollutants, Occupational; Aneuploidy; Benzene; Biomarkers; Centromere; Chromosomes, Human | 2010 |
Determination of genetic damage and urinary metabolites in fuel filling station attendants.
Topics: Acetylcysteine; Adult; Alcohol Drinking; Benzene; DNA Damage; Female; Gasoline; Humans; Male; Micron | 2011 |
Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes.
Topics: Acetylcysteine; Adult; Benzene; Environmental Pollutants; Epoxide Hydrolases; Female; Genotype; Glut | 2011 |
Prevention of benzene-induced genotoxicity in bone marrow and lung cells: superiority of polyphenolic acetates to polyphenols.
Topics: Acetates; Acetylation; Animals; Benzene; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Cells, Cul | 2011 |
Micronuclei levels in mothers and their newborns from regions with different types of air pollution.
Topics: Adolescent; Adult; Air Pollutants; Benzene; Benzo(a)pyrene; Body Mass Index; Czech Republic; Female; | 2011 |
Environmental exposure to benzene, micronucleus formation and polymorphisms in DNA-repair genes: a pilot study.
Topics: Adult; Benzene; DNA Repair; Environmental Exposure; Female; Humans; Male; Micronuclei, Chromosome-De | 2012 |
[Polymorphism of XRCC1 and chromosome damage in workers occupationally exposed to benzene].
Topics: Adult; Benzene; DNA Damage; DNA-Binding Proteins; Humans; Micronuclei, Chromosome-Defective; Micronu | 2012 |
Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.
Topics: Administration, Inhalation; Animals; Apoptosis; Benzene; Bone Marrow Cells; Cyclin-Dependent Kinase | 2003 |
The induction of micronuclei in bovine lymphocytes by exposure to benzene and S-9 mix.
Topics: Animals; Benzene; Carcinogens; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Lymphocyte | 2003 |
[The relativity between bone marrow mononuclear cells apoptosis and peripheral lymphocyte micronucleus in workers exposed to benzene].
Topics: Adult; Apoptosis; Benzene; Biomarkers; Bone Marrow Cells; Female; Flow Cytometry; Humans; Leukocytes | 2004 |
Association of the NQO1, MPO, and XRCC1 polymorphisms and chromosome damage among workers at a petroleum refinery.
Topics: Adult; Benzene; Case-Control Studies; DNA Repair; DNA-Binding Proteins; Genetic Predisposition to Di | 2008 |
Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice.
Topics: Animals; Atmosphere Exposure Chambers; Benzene; Benzene Derivatives; Body Weight; Bone Marrow Cells; | 2008 |
In vivo genotoxic interactions among three phenolic benzene metabolites.
Topics: Animals; Benzene; Catechols; Drug Interactions; Hydroquinones; Male; Mice; Micronuclei, Chromosome-D | 1994 |
Synergistic increase in chromosomal breakage within the euchromatin induced by an interaction of the benzene metabolites phenol and hydroquinone in mice.
Topics: Animals; Benzene; Chromatin; Chromosome Aberrations; DNA Repair; Drug Synergism; Hydroquinones; Male | 1995 |
Critical issues in benzene toxicity and metabolism: the effect of interactions with other organic chemicals on risk assessment.
Topics: Animals; Benzene; Bone Marrow; Cell Division; Drug Interactions; Ethanol; Female; Humans; Hydroquino | 1994 |
No increase in micronuclei frequency in cultured blood lymphocytes from a group of filling station attendants.
Topics: Adolescent; Adult; Benzene; Cells, Cultured; Gasoline; Hippurates; Humans; Leukocyte Count; Lymphocy | 1996 |
Symptoms, lung and liver function, blood counts, and genotoxic effects in coastal tanker crews.
Topics: Adolescent; Adult; Benzene; Blood Cell Count; Carcinogens; Case-Control Studies; Cross-Sectional Stu | 1997 |
Antigenotoxic effects of cimetidine against benzene induced micronuclei in mouse bone marrow erythrocytes.
Topics: Animals; Antimutagenic Agents; Benzene; Bone Marrow Cells; Cell Nucleus; Cimetidine; Dose-Response R | 1998 |
Chemoprevention of benzene-induced bone marrow and pulmonary genotoxicity.
Topics: Animals; Benzene; Bone Marrow; Bone Marrow Cells; Coumarins; Cyclopentanes; DNA Damage; Dose-Respons | 2001 |
Induction and time-dependent accumulation of micronuclei in peripheral blood of transgenic p53+/- mice, Tg.AC (v-Ha-ras) and parental wild-type (C57BL/6 and FVB/N) mice exposed to benzene by inhalation.
Topics: Animals; Benzene; Genes, p53; Genes, ras; Inhalation Exposure; Mice; Mice, Inbred C57BL; Mice, Inbre | 2001 |
Cytogenetic effects in rotogravure printers exposed to toluene (and benzene).
Topics: Adult; B-Lymphocytes; Benzene; Chromosome Aberrations; Humans; Lymphocyte Activation; Male; Micronuc | 1991 |
Benzene-induced micronuclei formation in mouse fetal liver blood, peripheral blood, and maternal bone marrow cells.
Topics: Animals; Benzene; Bone Marrow; Dose-Response Relationship, Drug; Erythrocytes; Female; Fetal Blood; | 1991 |
Characterization of micronuclei induced in human lymphocytes by benzene metabolites.
Topics: Adult; Benzene; Benzoquinones; Catechols; Cells, Cultured; Chromosome Aberrations; Dose-Response Rel | 1990 |
Genotoxicity of two metabolites of benzene: phenol and hydroquinone show strong synergistic effects in vivo.
Topics: Animals; Benzene; Dose-Response Relationship, Drug; Drug Synergism; Hydroxyquinolines; Injections, I | 1990 |
Effect of repeated benzene inhalation exposures on benzene metabolism, binding to hemoglobin, and induction of micronuclei.
Topics: Administration, Inhalation; Animals; Benzene; Carbon Radioisotopes; Drug Administration Schedule; En | 1990 |