benzene has been researched along with Cell Transformation, Neoplastic in 24 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Evidence indicates that acute myeloid leukemia arises as a secondary event, subsequent to evolution of the leukemia-initiating cell phenotype within the altered BM microenvironment." | 6.50 | Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum. ( Irons, RD; Kerzic, PJ, 2014) |
| "Chronic exposure to benzene results in progressive decline of hematopoietic function and may lead to the onset of various disorders, including aplastic anemia, myelodysplastic syndrome, and leukemia." | 3.72 | Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression. ( Abernethy, DJ; Faiola, B; Fuller, ES; Pluta, L; Recio, L; Rose, J; Wong, VA, 2004) |
| "Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML)." | 3.70 | The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 1999) |
| "Evidence indicates that acute myeloid leukemia arises as a secondary event, subsequent to evolution of the leukemia-initiating cell phenotype within the altered BM microenvironment." | 2.50 | Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum. ( Irons, RD; Kerzic, PJ, 2014) |
| "Benzene is an established human and animal carcinogen." | 2.44 | Benzene's toxicity: a consolidated short review of human and animal studies. ( Ahmad Khan, H, 2007) |
| "The first step in cancer initiation is the reaction of chemical carcinogens with DNA to form stable adducts, which remain in DNA unless removed by repair, and depurinating adducts, which detach from DNA following destabilization of the glycosyl bond." | 2.42 | A unifying mechanism in the initiation of cancer and other diseases by catechol quinones. ( Cavalieri, EL; Rogan, EG, 2004) |
| "Frequent karyotypic changes were trisomy 8 (9." | 1.38 | Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience. ( Alimena, G; Breccia, M; Finsinger, P; Latagliata, R; Loglisci, G; Nanni, M; Petrucci, L; Salaroli, A; Santopietro, M; Serrao, A; Volpicelli, P, 2012) |
| "Benzene is an organic solvent that has been used in industry for about 100 years throughout the world." | 1.33 | Progress of epidemiological and molecular epidemiological studies on benzene in China. ( Li, G; Yin, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (41.67) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ling, X | 1 |
| Pan, Z | 1 |
| Zhang, H | 1 |
| Wu, M | 1 |
| Gui, Z | 1 |
| Yuan, Q | 1 |
| Chen, J | 1 |
| Peng, J | 1 |
| Liu, Z | 1 |
| Tan, Q | 1 |
| Huang, D | 1 |
| Xiu, L | 1 |
| Liu, L | 1 |
| Zhao, J | 1 |
| Sui, P | 1 |
| Wu, B | 1 |
| Chen, A | 1 |
| Lu, Y | 1 |
| Hou, F | 1 |
| Cheng, X | 1 |
| Cui, S | 1 |
| Song, J | 1 |
| Huang, G | 1 |
| Xing, C | 1 |
| Wang, QF | 1 |
| Taş, İ | 1 |
| Zhou, R | 1 |
| Park, SY | 1 |
| Yang, Y | 1 |
| Gamage, CDB | 1 |
| Son, YJ | 1 |
| Paik, MJ | 1 |
| Kim, H | 1 |
| Irons, RD | 2 |
| Kerzic, PJ | 1 |
| Zahid, M | 1 |
| Saeed, M | 1 |
| Rogan, EG | 2 |
| Cavalieri, EL | 2 |
| Breccia, M | 1 |
| Finsinger, P | 1 |
| Loglisci, G | 1 |
| Santopietro, M | 1 |
| Salaroli, A | 1 |
| Serrao, A | 1 |
| Latagliata, R | 1 |
| Volpicelli, P | 1 |
| Petrucci, L | 1 |
| Nanni, M | 1 |
| Alimena, G | 1 |
| Faiola, B | 1 |
| Fuller, ES | 1 |
| Wong, VA | 1 |
| Pluta, L | 1 |
| Abernethy, DJ | 1 |
| Rose, J | 1 |
| Recio, L | 1 |
| Li, G | 1 |
| Yin, S | 1 |
| Ahmad Khan, H | 1 |
| Snyder, R | 1 |
| Atkinson, TJ | 1 |
| Joseph, P | 1 |
| Klein-Szanto, AJ | 1 |
| Jaiswal, AK | 1 |
| Stillman, WS | 1 |
| Varella-Garcia, M | 1 |
| Moloney, WC | 1 |
| Heidelberger, C | 1 |
| Zhang, ZZ | 1 |
| Zeng, XG | 1 |
| Guo, JT | 1 |
| Sun, ML | 1 |
| Zhang, XL | 1 |
| Dean, BJ | 1 |
| Rhim, JS | 2 |
| Gordon, RJ | 2 |
| Bryan, RJ | 2 |
| Huebner, RJ | 2 |
| Seilern-Aspang, F | 1 |
| Mazzucco, K | 1 |
| Christian, I | 1 |
| Mey, U | 1 |
| Demoise, C | 1 |
| Wolford, RG | 1 |
| Freeman, AE | 1 |
| Hori, SH | 1 |
| Sasaki, M | 1 |
8 reviews available for benzene and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum.
Topics: Animals; Benzene; Cell Transformation, Neoplastic; Cytogenetic Analysis; Disease Progression; Epigen | 2014 |
A unifying mechanism in the initiation of cancer and other diseases by catechol quinones.
Topics: Animals; Benzene; Breast Neoplasms; Carcinogens; Catechols; Cell Line, Tumor; Cell Proliferation; Ce | 2004 |
Benzene's toxicity: a consolidated short review of human and animal studies.
Topics: Animals; Benzene; Biotransformation; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; D | 2007 |
A review of the role of benzene metabolites and mechanisms in malignant transformation: summative evidence for a lack of research in nonmyelogenous cancer types.
Topics: Benzene; Carcinogens; Cell Transformation, Neoplastic; Hemolytic Agents; Humans; Neoplasms; Occupati | 2009 |
Natural history of chronic granulocytic leukaemia.
Topics: Adult; Animals; Benzene; Cell Differentiation; Cell Transformation, Neoplastic; Female; Granulocytes | 1977 |
Chemical carcinogenesis.
Topics: Aflatoxins; Amines; Animals; Benzene; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; | 1975 |
Recent findings on the genetic toxicology of benzene, toluene, xylenes and phenols.
Topics: Animals; Bacteria; Benzene; Carcinogens; Cell Transformation, Neoplastic; Drosophila melanogaster; D | 1985 |
[Etiology of human leukemias].
Topics: Age Factors; Benzene; Cell Transformation, Neoplastic; Chloramphenicol; Hematopoietic Stem Cells; Hu | 1974 |
16 other studies available for benzene and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
PARP-1 modulates the expression of miR-223 through histone acetylation to involve in the hydroquinone-induced carcinogenesis of TK6 cells.
Topics: Acetylation; Benzene; Cell Transformation, Neoplastic; Epigenesis, Genetic; Histones; Humans; Hydroq | 2022 |
Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine model.
Topics: Animals; Benzene; Bone Marrow Cells; Cell Transformation, Neoplastic; Disease Models, Animal; Leukem | 2021 |
Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells.
Topics: Benzene; Benzo(a)pyrene; Cadmium; Carcinogens; Cell Line; Cell Membrane Permeability; Cell Transform | 2019 |
Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease.
Topics: Aminobutyrates; Animals; Benzene; Catechols; Cattle; Cell Transformation, Neoplastic; Chromatography | 2010 |
Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience.
Topics: Acute Disease; Adult; Aged; Analysis of Variance; Benzene; Cell Transformation, Neoplastic; Chromoso | 2012 |
Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.
Topics: Animals; Apoptosis; Benzene; Benzoquinones; Carcinogens; Cell Cycle Proteins; Cell Transformation, N | 2004 |
Progress of epidemiological and molecular epidemiological studies on benzene in China.
Topics: Benzene; Cell Transformation, Neoplastic; China; Cohort Studies; Dose-Response Relationship, Drug; H | 2006 |
Benzene's toxicity: a consolidated short review of human and animal studies by HA Khan.
Topics: Animals; Benzene; Biotransformation; Bone Marrow; Cell Transformation, Neoplastic; Chromosome Aberra | 2007 |
Hydroquinones cause specific mutations and lead to cellular transformation and in vivo tumorigenesis.
Topics: 3T3 Cells; Animals; Benzene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cult | 1998 |
The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line.
Topics: Benzene; Catechols; Cell Transformation, Neoplastic; Chromosome Deletion; Chromosomes, Human, Pair 5 | 1999 |
[In vitro transformation of Syrian hamster embryo cells by four chemicals].
Topics: Animals; Benzene; Cell Transformation, Neoplastic; Cells, Cultured; Coal; Cricetinae; Embryo, Mammal | 1989 |
Cancer risk and viral transformation.
Topics: Benzene; Carcinogens; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; | 1969 |
Transformation of mouse cells infected with AKR leukemia virus by benzene extact fractions of city air particles.
Topics: Acetone; Animals; Benzene; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Ce | 1973 |
[Influence of methylcholanthrene on synthesis, cross-linkage and degradation of mouse dermis collagen, and the possible significance of this degradation for malignant growth].
Topics: Animals; Back; Benzene; Cell Transformation, Neoplastic; Citrates; Collagen; Cysteamine; Electrophor | 1969 |
Transformation of rat and mouse embryo cells by a new class of carcinogenic compounds isolated from particles in city air.
Topics: Air Pollution; Animals; Antibody Formation; Benzene; Benzopyrenes; California; Carcinogens; Cell Lin | 1973 |
Glucose 6-phosphate dehydrogenase isoenzyme patterns and chromosomes in primary liver tumors of the rat.
Topics: Animals; Azo Compounds; Benzene; Cell Transformation, Neoplastic; Cytogenetics; Female; Glucosephosp | 1969 |