Page last updated: 2024-10-16
benzene and Aneuploid
benzene has been researched along with Aneuploid in 22 studies
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "An overall hypothesis for benzene-induced leukemia is proposed." | 8.79 | The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia. ( Smith, MT, 1996) |
| " This article presents an overview of work that has been performed using recently developed molecular cytogenic techniques to investigate the aneuploidy-inducing and clastogenic properties of the major quinone-forming metabolites of benzene, a widely used industrial chemical, and o-phenylphenol, a fungicide and disinfectant." | 8.78 | Induction of micronuclei and aneuploidy by the quinone-forming agents benzene and o-phenylphenol. ( Eastmond, DA, 1993) |
| "Evidence suggests that de novo, therapy-related and benzene-induced acute myeloid leukemias (AML) occur via similar cytogenetic and genetic pathways, several of which involve aneuploidy, the loss or gain of chromosomes." | 7.77 | Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene. ( Guo, W; Hubbard, AE; Ji, Z; Lan, Q; Li, G; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2011) |
| "Benzene is a common industrial chemical known to induce leukemia and other blood disorders, as well as aneuploidy, in both human blood cells and sperm at exposures > 10 ppm." | 7.76 | Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy. ( Eskenazi, B; Kurtovich, E; Li, G; Marchetti, F; Rappaport, S; Schmid, TE; Waidyanatha, S; Weldon, RH; Wyrobek, AJ; Xing, C; Young, S; Zhang, L, 2010) |
| "Previously, we have shown that phenyl hydroquinone, a hepatic metabolite of the Ames test-negative carcinogen o-phenylphenol, efficiently induced aneuploidy in Saccharomyces cerevisiae by arresting the cell cycle at the G2/M transition as a result of the activation of the Hog1 (p38 MAPK homolog)-Swe1 (Wee1 homolog) pathway." | 7.76 | Hydroquinone, a benzene metabolite, induces Hog1-dependent stress response signaling and causes aneuploidy in Saccharomyces cerevisiae. ( Shiga, T; Suzuki, H; Yamamoto, A; Yamamoto, H; Yamamoto, K, 2010) |
| "Exposure to high-dose benzene via gavage or inhalation was able to induce increase in aneuploidy frequency of M II oocytes in mice." | 7.71 | [Study on frequencies of aneuploidy in mouse oocyte and female pronucleus of one cell zygote induced by benzene]. ( Deng, L; Zeng, Q; Zheng, L, 2001) |
| "Benzene is a primary industrial chemical and a ubiquitous environmental pollutant that causes human leukemia and maybe other malignancies." | 5.38 | Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzene. ( Chen, H; Eskenazi, B; Ji, Z; Kurtovich, E; Li, G; Marchetti, F; Rappaport, S; Schmid, TE; Waidyanatha, S; Weldon, RH; Xing, C; Young, S; Zhang, L, 2012) |
| "Benzene (bz) is a common environmental contaminant associated with increased risk of myeloid leukemia." | 5.31 | Persistence of aneuploid immature/primitive hemopoietic sub-populations in mice 8 months after benzene exposure in vivo. ( Giver, CR; Moore, DH; Pallavicini, MG; Wong, R, 2001) |
| "Six days after bz or TCE exposure, aneuploid cells in the hsc compartment increase four- to eightfold in a dose- and schedule-independent manner." | 5.31 | Dermal benzene and trichloroethylene induce aneuploidy in immature hematopoietic subpopulations in vivo. ( Giver, CR; Moore, DH; Pallavicini, MG; Wong, R, 2001) |
| "Benzene is a human carcinogen present naturally in petroleum and gasoline." | 5.30 | Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells. ( Barrett, JC; Hayashi, N; Huff, J; Maizumi, H; Tsutsui, T, 1997) |
| "Benzene is an established human leukemogen that increases the level of chromosome aberrations in lymphocytes of exposed workers." | 5.30 | Benzene increases aneuploidy in the lymphocytes of exposed workers: a comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells. ( Dosemeci, M; Hayes, RB; Kolachana, P; Li, GL; Lu, W; Rothman, N; Smith, MT; Titenko-Holland, N; Wang, Y; Wang, YZ; Xi, L; Yin, S; Zhang, L, 1999) |
| "An overall hypothesis for benzene-induced leukemia is proposed." | 4.79 | The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia. ( Smith, MT, 1996) |
| " This article presents an overview of work that has been performed using recently developed molecular cytogenic techniques to investigate the aneuploidy-inducing and clastogenic properties of the major quinone-forming metabolites of benzene, a widely used industrial chemical, and o-phenylphenol, a fungicide and disinfectant." | 4.78 | Induction of micronuclei and aneuploidy by the quinone-forming agents benzene and o-phenylphenol. ( Eastmond, DA, 1993) |
| "Evidence suggests that de novo, therapy-related and benzene-induced acute myeloid leukemias (AML) occur via similar cytogenetic and genetic pathways, several of which involve aneuploidy, the loss or gain of chromosomes." | 3.77 | Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene. ( Guo, W; Hubbard, AE; Ji, Z; Lan, Q; Li, G; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2011) |
| "Benzene is a well-known carcinogen that induces chromosomal instability, including chromosome aberration and aneuploidy." | 3.76 | Micronucleus-centromere assay in workers occupationally exposed to low level of benzene. ( , 2010) |
| "Benzene is a common industrial chemical known to induce leukemia and other blood disorders, as well as aneuploidy, in both human blood cells and sperm at exposures > 10 ppm." | 3.76 | Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy. ( Eskenazi, B; Kurtovich, E; Li, G; Marchetti, F; Rappaport, S; Schmid, TE; Waidyanatha, S; Weldon, RH; Wyrobek, AJ; Xing, C; Young, S; Zhang, L, 2010) |
| "Exposed to benzene at higher concentration may induce increase in aneuploidy frequency of sperm sex chromosome in exposed workers." | 3.70 | [Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization]. ( Deng, L; Liu, S; Tang, G; Zhang, Q; Zheng, L, 2000) |
| "Benzene exposure causes acute myeloid leukemia and hematotoxicity, shown as suppression of mature blood and myeloid progenitor cell numbers." | 1.38 | Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Ji, Z; Lan, Q; Li, G; Linet, MS; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2012) |
| "Benzene is a human carcinogen present naturally in petroleum and gasoline." | 1.30 | Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells. ( Barrett, JC; Hayashi, N; Huff, J; Maizumi, H; Tsutsui, T, 1997) |
| "Benzene is an established human leukemogen that increases the level of chromosome aberrations in lymphocytes of exposed workers." | 1.30 | Benzene increases aneuploidy in the lymphocytes of exposed workers: a comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells. ( Dosemeci, M; Hayes, RB; Kolachana, P; Li, GL; Lu, W; Rothman, N; Smith, MT; Titenko-Holland, N; Wang, Y; Wang, YZ; Xi, L; Yin, S; Zhang, L, 1999) |
| "Benzene is a widely recognized human and animal carcinogen." | 1.29 | Chromosomal loss and breakage in mouse bone marrow and spleen cells exposed to benzene in vivo. ( Chen, H; Eastmond, DA; Rupa, DS; Tomar, R, 1994) |
Research
Studies (22)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Xing, C | 2 |
| Marchetti, F | 2 |
| Li, G | 5 |
| Weldon, RH | 2 |
| Kurtovich, E | 2 |
| Young, S | 2 |
| Schmid, TE | 2 |
| Zhang, L | 6 |
| Rappaport, S | 2 |
| Waidyanatha, S | 2 |
| Wyrobek, AJ | 1 |
| Eskenazi, B | 2 |
| Shiga, T | 1 |
| Suzuki, H | 1 |
| Yamamoto, A | 1 |
| Yamamoto, H | 1 |
| Yamamoto, K | 1 |
| Lan, Q | 2 |
| Guo, W | 2 |
| Hubbard, AE | 2 |
| Rappaport, SM | 2 |
| McHale, CM | 2 |
| Shen, M | 2 |
| Ji, Z | 3 |
| Vermeulen, R | 2 |
| Yin, S | 4 |
| Rothman, N | 4 |
| Smith, MT | 5 |
| Chen, H | 2 |
| Hayes, RB | 3 |
| Linet, MS | 1 |
| Rupa, DS | 1 |
| Tomar, R | 1 |
| Eastmond, DA | 2 |
| Tsutsui, T | 1 |
| Hayashi, N | 1 |
| Maizumi, H | 1 |
| Huff, J | 1 |
| Barrett, JC | 1 |
| Wang, Y | 3 |
| Bechtold, W | 1 |
| Venkatesh, P | 1 |
| Dosemeci, M | 2 |
| Lu, W | 2 |
| Carere, A | 2 |
| Antoccia, A | 1 |
| Cimini, D | 1 |
| Crebelli, R | 2 |
| Degrassi, F | 1 |
| Leopardi, P | 1 |
| Marcon, F | 2 |
| Sgura, A | 1 |
| Tanzarella, C | 2 |
| Zijno, A | 2 |
| Ranaldi, R | 1 |
| Bassani, B | 1 |
| Villani, P | 1 |
| Lombardi, CC | 1 |
| Pacchierotti, F | 1 |
| Veidebaum, T | 1 |
| Peltonen, K | 1 |
| Parks, R | 1 |
| Schuler, M | 1 |
| Eastmond, D | 1 |
| Titenko-Holland, N | 1 |
| Wang, YZ | 1 |
| Kolachana, P | 1 |
| Xi, L | 1 |
| Li, GL | 1 |
| Giver, CR | 2 |
| Wong, R | 2 |
| Moore, DH | 2 |
| Pallavicini, MG | 2 |
| Zeng, Q | 1 |
| Zheng, L | 2 |
| Deng, L | 2 |
| Liu, S | 1 |
| Tang, G | 1 |
| Zhang, Q | 1 |
| Pollini, G | 1 |
| Biscaldi, GP | 1 |
| Miller, RW | 1 |
| Forni, AM | 1 |
| Cappellini, A | 1 |
| Pacifico, E | 1 |
| Vigliani, EC | 1 |
Reviews
2 reviews available for benzene and Aneuploid
| Article | Year |
|---|---|
Induction of micronuclei and aneuploidy by the quinone-forming agents benzene and o-phenylphenol.
Topics: Aneuploidy; Animals; Benzene; Biphenyl Compounds; Carcinogens; Humans; Micronucleus Tests; Mutagenic | 1993 |
The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia.
Topics: Aneuploidy; Animals; Benzene; Carcinogens; Humans; Leukemia; Liver; Models, Biological; Phenols; Rec | 1996 |
Other Studies
20 other studies available for benzene and Aneuploid
| Article | Year |
|---|---|
Micronucleus-centromere assay in workers occupationally exposed to low level of benzene.
Topics: Adult; Air Pollutants, Occupational; Aneuploidy; Benzene; Biomarkers; Centromere; Chromosomes, Human | 2010 |
Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy.
Topics: Aneuploidy; Benzene; China; Chromosome Aberrations; Environmental Pollutants; Humans; In Situ Hybrid | 2010 |
Hydroquinone, a benzene metabolite, induces Hog1-dependent stress response signaling and causes aneuploidy in Saccharomyces cerevisiae.
Topics: Aneuploidy; Benzene; Cell Cycle; Cell Cycle Proteins; Checkpoint Kinase 2; Genes, Fungal; Hydroquino | 2010 |
Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene.
Topics: Adult; Aneuploidy; Benzene; Chromosomes, Human, X; Dose-Response Relationship, Drug; Female; Humans; | 2011 |
Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzene.
Topics: Air Pollutants; Aneuploidy; Benzene; China; Chromosomes, Human, Pair 21; Chromosomes, Human, X; Chro | 2012 |
Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers.
Topics: Adult; Aneuploidy; Benzene; Case-Control Studies; Chromosome Deletion; Chromosomes, Human, Pair 7; C | 2012 |
Chromosomal loss and breakage in mouse bone marrow and spleen cells exposed to benzene in vivo.
Topics: Aneuploidy; Animals; Antibodies; Base Sequence; Benzene; Bone Marrow Cells; Chromosome Aberrations; | 1994 |
Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells.
Topics: Aneuploidy; Animals; Benzene; Carcinogens; Catechols; Cells, Cultured; Chromosome Aberrations; Crice | 1997 |
Interphase cytogenetics of workers exposed to benzene.
Topics: Adult; Aneuploidy; Benzene; Carcinogens; Case-Control Studies; Chromosomes, Human, Pair 7; Chromosom | 1996 |
Genetic effects of petroleum fuels: II. Analysis of chromosome loss and hyperploidy in peripheral lymphocytes of gasoline station attendants.
Topics: Air Pollutants, Occupational; Aneuploidy; Benzene; Cell Cycle; Cells, Cultured; Chromosome Deletion; | 1998 |
Measurement and characterization of micronuclei in cultured primary lung cells of mice following inhalation exposure to benzene.
Topics: Administration, Inhalation; Aneuploidy; Animals; Benzene; Cells, Cultured; Chromosome Aberrations; D | 1998 |
Chromosome damage and aneuploidy detected by interphase multicolour FISH in benzene-exposed shale oil workers.
Topics: Adult; Aneuploidy; Benzene; Cells, Cultured; Chromosome Breakage; Chromosomes, Human, Pair 1; Chromo | 1999 |
Benzene increases aneuploidy in the lymphocytes of exposed workers: a comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells.
Topics: Adult; Aneuploidy; Benzene; Case-Control Studies; Chromosomes, Human, Pair 7; Chromosomes, Human, Pa | 1999 |
Persistence of aneuploid immature/primitive hemopoietic sub-populations in mice 8 months after benzene exposure in vivo.
Topics: Aneuploidy; Animals; Benzene; Bone Marrow Cells; Female; Male; Mice; Mice, Inbred C57BL | 2001 |
Dermal benzene and trichloroethylene induce aneuploidy in immature hematopoietic subpopulations in vivo.
Topics: Administration, Cutaneous; Aneuploidy; Animals; Antigens, Ly; Benzene; Bone Marrow Cells; Cell Divis | 2001 |
[Study on frequencies of aneuploidy in mouse oocyte and female pronucleus of one cell zygote induced by benzene].
Topics: Aneuploidy; Animals; Benzene; Female; Mice; Oocytes; Zygote | 2001 |
[Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization].
Topics: Adult; Air Pollutants, Occupational; Aneuploidy; Benzene; Chromosome Aberrations; Female; Humans; In | 2000 |
[Persistence of karyotype alterations in lymphocytes 10 years after benzene poisoning].
Topics: Aneuploidy; Benzene; Diploidy; Female; Humans; Karyotyping; Lymphocytes; Occupational Diseases; Pois | 1976 |
Persons with exceptionally high risk of leukemia.
Topics: Adult; Aneuploidy; Benzene; Child; Child, Preschool; Chromosome Aberrations; Diseases in Twins; Down | 1967 |
Chromosome changes and their evolution in subjects with past exposure to benzene.
Topics: Adult; Aneuploidy; Benzene; Blood Cell Count; Bone Marrow Cells; Cell Division; Chromosome Aberratio | 1971 |