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benzene and Acute Promyelocytic Leukemia

benzene has been researched along with Acute Promyelocytic Leukemia in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Benzene is a well known environmental carcinogen which causes myeloid leukemia."1.35Generation of phosphorylated histone H2AX by benzene metabolites. ( Ibuki, Y; Ishihama, M; Toyooka, T, 2008)
" Comparison of the slopes of the dose-response curves showed that hydroquinone was 7-9 times more effective than 1,2,4,-benzenetriol and catechol at inducing DNA adducts."1.28Potentiation of DNA adduct formation in HL-60 cells by combinations of benzene metabolites. ( Bodell, WJ; Lévay, G, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishihama, M1
Toyooka, T1
Ibuki, Y1
Hazel, BA1
O'Connor, A2
Niculescu, R1
Kalf, GF2
Kolachana, P1
Subrahmanyam, VV1
Meyer, KB1
Zhang, L1
Smith, MT1
Lévay, G1
Bodell, WJ1

Reviews

1 review available for benzene and Acute Promyelocytic Leukemia

ArticleYear
The effects of benzene and hydroquinone on myeloid differentiation of HL-60 promyelocytic leukemia cells.
    Leukemia & lymphoma, 1993, Volume: 11, Issue:5-6

    Topics: Arachidonate 5-Lipoxygenase; Benzene; Cell Differentiation; Enzyme Activation; Granulocytes; Humans;

1993

Other Studies

4 other studies available for benzene and Acute Promyelocytic Leukemia

ArticleYear
Generation of phosphorylated histone H2AX by benzene metabolites.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:8

    Topics: Benzene; Benzoquinones; Cell Survival; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug

2008
Benzene and its metabolite, hydroquinone, induce granulocytic differentiation in myeloblasts by interacting with cellular signaling pathways activated by granulocyte colony-stimulating factor.
    Stem cells (Dayton, Ohio), 1995, Volume: 13, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Benzene; Cell Differentiation; Cell Division; Cell Line; Granu

1995
Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo.
    Cancer research, 1993, Mar-01, Volume: 53, Issue:5

    Topics: Animals; Benzene; Bone Marrow; Catechols; DNA; DNA Damage; Humans; Hydroquinones; Leukemia, Promyelo

1993
Potentiation of DNA adduct formation in HL-60 cells by combinations of benzene metabolites.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-01, Volume: 89, Issue:15

    Topics: Autoradiography; Benzene; Benzoquinones; Catechols; Cell Line; Cell Survival; DNA, Neoplasm; Humans;

1992