Page last updated: 2024-10-16

benzene and Acute Myelogenous Leukemia

benzene has been researched along with Acute Myelogenous Leukemia in 119 studies

Research Excerpts

ExcerptRelevanceReference
"Chronic exposure to high concentrations of benzene is an established cause of acute myeloid leukemia (AML) in occupationally exposed workers."8.86A review of the potential association between childhood leukemia and benzene. ( Hays, S; Pyatt, D, 2010)
"Our study provides consistent evidence that exposure to benzene at work increases the risk of leukemia with a dose-response pattern."8.86Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010)
"Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia."7.78Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012)
"Cigarette smoking is associated with an increased risk of leukemia; benzene, an established leukemogen, is present in cigarette smoke."7.70The contribution of benzene to smoking-induced leukemia. ( Ball, LM; Duell, EJ; Hertz-Picciotto, I; Korte, JE; Schulz, MR, 2000)
"This report updates the risk assessment by Crump and Allen for benzene-induced leukemia that was based on a cohort exposed to benzene in the manufacture of Pliofilm."7.69Risk of benzene-induced leukemia predicted from the Pliofilm cohort. ( Crump, KS, 1996)
"This report updates the risk assessment by Crump and Allen (1984) for benzene-induced leukemia that was used by OSHA (1987) to support its reduction of the permissible exposure limit (PEL) to 1 ppm and that also was the basis for EPA's (1985) interim "unit risk" for benzene."7.69Risk of benzene-induced leukemia: a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates. ( Crump, KS, 1994)
"Benzene has the sad privilege of being the only industrial chemical inducing leukemia in susceptible individuals chronically exposed to its vapors."7.66An hypothesis for the induction of leukemia by benzene. ( Braier, L, 1983)
"The distribution of various types of leukemia due to chronic exposure to benzene is described in a series comprising 34 cases."7.65Types of leukemia in chronic benzene poisoning. A study in thirty-four patients. ( Aksoy, M; Dinçol, G; Erdem, S, 1976)
"Evidence indicates that acute myeloid leukemia arises as a secondary event, subsequent to evolution of the leukemia-initiating cell phenotype within the altered BM microenvironment."6.50Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum. ( Irons, RD; Kerzic, PJ, 2014)
"The meta-SMR for acute myeloid leukemia was 0."6.39Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996)
" The dose-response relationship is strongly nonlinear."6.38Consistencies and inconsistencies underlying the quantitative assessment of leukemia risk from benzene exposure. ( Byrd, DM; Grunwald, H; Lamm, SH; Walters, AS; Wilson, R, 1989)
"We assessed three study quality dimensions to evaluate the impact of study quality variations on meta-relative risks (mRRs): stratification by the year of start of follow-up, stratification by the strength of the reported acute myelogenous leukemia association, and stratification by the quality of benzene exposure assessment."4.87Occupational benzene exposure and the risk of lymphoma subtypes: a meta-analysis of cohort studies incorporating three study quality dimensions. ( Kromhout, H; Lan, Q; Rothman, N; Vermeulen, R; Vlaanderen, J, 2011)
"Chronic exposure to high concentrations of benzene is an established cause of acute myeloid leukemia (AML) in occupationally exposed workers."4.86A review of the potential association between childhood leukemia and benzene. ( Hays, S; Pyatt, D, 2010)
"Our study provides consistent evidence that exposure to benzene at work increases the risk of leukemia with a dose-response pattern."4.86Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010)
" Over the last half-century a predominant paradigm has emerged to describe leukemia developing secondary to alkylating drug therapy or exposure to benzene in which progressive dysplastic changes, accompanied by a distinct pattern of clonal cytogenetic abnormalities, give rise to acute myelogenous leukemia."4.79The process of leukemogenesis. ( Irons, RD; Stillman, WS, 1996)
"There is international consensus that benzene exposure is causally related to acute myeloid leukemia (AML), and more recent evidence of association with myelodysplastic syndromes (MDS)."3.91Benzene Exposure Response and Risk of Myeloid Neoplasms in Chinese Workers: A Multicenter Case-Cohort Study. ( Dores, GM; Gilbert, ES; Hayes, RB; Ji, BT; Lan, Q; Li, GL; Linet, MS; Portengen, L; Rothman, N; Vermeulen, R; Yin, SN, 2019)
"High benzene exposure is related to acute nonlymphocytic leukemia."3.81Lymphatic and hematopoietic cancers among benzene-exposed workers. ( Anteau, SE; Bodnar, CM; Bodner, KM; Collins, JJ; Swaen, GM, 2015)
"Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia."3.78Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012)
"Benzene exposure is associated with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and probably lymphoma and childhood leukemia."3.77Benzene, the exposome and future investigations of leukemia etiology. ( McHale, CM; Rappaport, SM; Skibola, CF; Smith, MT; Zhang, L, 2011)
"Benzene exposure has been shown to be related to acute myelogenous leukemia, while the association with multiple myeloma and non-Hodgkin lymphoma has been a much-debated issue."3.74Increased risk of acute myelogenous leukemia and multiple myeloma in a historical cohort of upstream petroleum workers exposed to crude oil. ( Bråtveit, M; Kirkeleit, J; Moen, BE; Riise, T, 2008)
"Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML)."3.70The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 1999)
"Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome and acute myelogenous leukemia."3.70The benzene metabolite, hydroquinone, selectively induces 5q31- and -7 in human CD34+CD19- bone marrow cells. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 2000)
"Cigarette smoking is associated with an increased risk of leukemia; benzene, an established leukemogen, is present in cigarette smoke."3.70The contribution of benzene to smoking-induced leukemia. ( Ball, LM; Duell, EJ; Hertz-Picciotto, I; Korte, JE; Schulz, MR, 2000)
"This report updates the risk assessment by Crump and Allen for benzene-induced leukemia that was based on a cohort exposed to benzene in the manufacture of Pliofilm."3.69Risk of benzene-induced leukemia predicted from the Pliofilm cohort. ( Crump, KS, 1996)
"Benzene is a clastogenic and carcinogenic agent that induces acute myelogenous leukemia in humans and multiple of tumors in animals."3.69Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites. ( Chen, H; Eastmond, DA; Frantz, CE, 1996)
"Chronic exposure of humans to benzene causes acute myelogenous leukemia (AML)."3.69Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone. ( Hazel, BA; Kalf, GF; Niculescu, R; O'Connor, A, 1996)
"Chronic exposure of humans to benzene (BZ), a Class I carcinogen, causes acute myelogenous leukemia, possibly via its bone marrow metabolite, hydroquinone (HQ)."3.69Induction of granulocytic differentiation in myeloblasts by hydroquinone, a metabolite of benzene, involves the leukotriene D4 receptor. ( Hazel, BA; Kalf, GF, 1996)
"This report updates the risk assessment by Crump and Allen (1984) for benzene-induced leukemia that was used by OSHA (1987) to support its reduction of the permissible exposure limit (PEL) to 1 ppm and that also was the basis for EPA's (1985) interim "unit risk" for benzene."3.69Risk of benzene-induced leukemia: a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates. ( Crump, KS, 1994)
"Benzene has the sad privilege of being the only industrial chemical inducing leukemia in susceptible individuals chronically exposed to its vapors."3.66An hypothesis for the induction of leukemia by benzene. ( Braier, L, 1983)
"The distribution of various types of leukemia due to chronic exposure to benzene is described in a series comprising 34 cases."3.65Types of leukemia in chronic benzene poisoning. A study in thirty-four patients. ( Aksoy, M; Dinçol, G; Erdem, S, 1976)
"Are dose-response relationships for benzene and health effects such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) supra-linear, with disproportionately high risks at low concentrations, e."2.72The shape of low-concentration dose-response functions for benzene: implications for human health risk assessment. ( Cox, LA; Ketelslegers, HB; Lewis, RJ, 2021)
"Benzene is an established cause of adult leukemia, but whether it is associated with childhood leukemia remains unclear."2.53Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis. ( Carlos-Wallace, FM; Rader, G; Smith, MT; Steinmaus, C; Zhang, L, 2016)
"Evidence indicates that acute myeloid leukemia arises as a secondary event, subsequent to evolution of the leukemia-initiating cell phenotype within the altered BM microenvironment."2.50Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum. ( Irons, RD; Kerzic, PJ, 2014)
"We report seven cases of acute myeloid leukemia (AML) with occupational exposure to a toluene-based hydrocarbon solvent."2.50Benzene-contaminated toluene and acute myeloid leukemia: a case series and review of literature. ( Dahlgren, J; Klein, J; Kopstein, M; Peckham, T, 2014)
"Cumulative benzene exposure showed a monotonic dose-response relationship with MDS (highest vs lowest tertile, >2."2.48Myelodysplastic syndrome and benzene exposure among petroleum workers: an international pooled analysis. ( Glass, DC; Irons, RD; Rushton, L; Schnatter, AR; Tang, G, 2012)
"Hydroquinone is a phenolic metabolite of benzene, a known human carcinogen."2.48Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature. ( Brautbar, N; Regev, L; Wu, M; Zlotolow, R, 2012)
"Benzene is a ubiquitous chemical in our environment that causes acute leukemia and probably other hematological cancers."2.46Advances in understanding benzene health effects and susceptibility. ( Smith, MT, 2010)
" The epidemiological evidence suggests that acute myelogenous leukemia (AML) associated with chronic occupational benzene exposure can be best described by sigmoid dose-response relationships."2.44Is benzene exposure from gasoline carcinogenic? ( Jamall, IS; Willhite, CC, 2008)
"Benzene has long been recognised as a carcinogen and recent concern has centred on the effects of continuous exposure to low concentrations of benzene both occupationally and environmentally."2.41Benzene in the environment: an assessment of the potential risks to the health of the population. ( Courage, C; Duarte-Davidson, R; Levy, L; Rushton, L, 2001)
"Risks of acute myeloid leukemia and other malignant and nonmalignant hematopoietic disorders associated with benzene exposure in China are consistent with other information about benzene exposure, hematotoxicity, and cancer risk, extending evidence for hematopoietic cancer risks to levels substantially lower than had previously been established."2.41Benzene and lymphohematopoietic malignancies in humans. ( Dosemeci, M; Hayes, RB; Linet, M; Songnian, Y, 2001)
"The meta-SMR for acute myeloid leukemia was 0."2.39Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996)
" The dose-response relationship is strongly nonlinear."2.38Consistencies and inconsistencies underlying the quantitative assessment of leukemia risk from benzene exposure. ( Byrd, DM; Grunwald, H; Lamm, SH; Walters, AS; Wilson, R, 1989)
"Benzene exposure can induce chromosome aberrations in somatic cells (lymphocytes and bone marrow cells) of man and of experimental animals in vivo, as well as in some in vitro systems."2.36Chromosome changes and benzene exposure. A review. ( Forni, A, 1979)
"Benzene poisoning can cause acute myeloid leukemia (AML) through a variety of passways."1.91Tim-3 facilitates immune escape in benzene-induced acute myeloid leukemia mouse model by promoting macrophage M2 polarization. ( Cui, S; He, X; Jian, T; Jian, X; Li, X; Ning, Q; Shi, L; Zhang, X, 2023)
"We estimated the ERC for benzene and acute myeloid leukemia (AML), by fitting linear and spline-based Bayesian meta-regression models that included summary risk estimates from non-AML and nonhuman studies as prior information."1.72Estimation of the Exposure-Response Relation between Benzene and Acute Myeloid Leukemia by Combining Epidemiologic, Human Biomarker, and Animal Data. ( Downward, GS; Portengen, L; Pronk, A; Scholten, B; Stierum, R; Vermeulen, R; Vlaanderen, J, 2022)
"Benzene exposure is a risk factor of acute myeloid leukemia (AML), during such carcinogenesis long non-coding RNAs (lncRNAs) are important epigenetic regulators."1.56Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene. ( Ling, X; Liu, L; Pan, Z; Tan, Q; Wu, M; Xie, D; Xie, P; Yuan, Q; Zhang, H; Zheng, D, 2020)
" The response patterns of majority of genes as captured by mean estimates of the first and second principal components of the dose-response for the five pathways and the profiles of 6 AML pathway response-representative genes (identified by clustering) exhibited similar apparent supra-linear responses."1.40Characterization of changes in gene expression and biochemical pathways at low levels of benzene exposure. ( Guyton, KZ; Hubbard, AE; Jinot, J; Lan, Q; McHale, CM; Rappaport, SM; Rothman, N; Smith, MT; Sonawane, BR; Thomas, R; Vermeulen, R; Zhang, L, 2014)
"Benzene exposures were much lower than previous studies."1.40Acute myeloid and chronic lymphoid leukaemias and exposure to low-level benzene among petroleum workers. ( Glass, DC; Rushton, L; Schnatter, AR; Tang, G, 2014)
"Benzene is a known environmental pollutant with demonstrated leukemogenic activity."1.38How benzene and its metabolites affect human marrow derived mesenchymal stem cells. ( Amirizadeh, N; Hosseinkhani, S; Nazem, S; Sadeghizadeh, M; Zolghadr, F, 2012)
"Benzene exposure causes acute myeloid leukemia and hematotoxicity, shown as suppression of mature blood and myeloid progenitor cell numbers."1.38Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Ji, Z; Lan, Q; Li, G; Linet, MS; McHale, CM; Rappaport, SM; Rothman, N; Shen, M; Smith, MT; Vermeulen, R; Yin, S; Zhang, L, 2012)
"Benzene is an established leukemogen at high exposure levels."1.38Increased mitochondrial DNA copy number in occupations associated with low-dose benzene exposure. ( Albetti, B; Baccarelli, A; Bertazzi, PA; Bollati, V; Bonzini, M; Byun, HM; Carugno, M; Cipolla, M; Cocco, P; Dioni, L; Fustinoni, S; Hoxha, M; Merlo, DF; Pesatori, AC; Satta, G; Zucca, M, 2012)
" The network was used to perform the biomarker-based dose-response analysis, and various other approaches to the dose-response analysis were conducted for comparison."1.36A Bayesian network model for biomarker-based dose response. ( Fowler, B; Haber, LT; Hack, CE; Lotz, WG; Maier, A; Savage, RE; Shulte, P, 2010)
" The results suggest that risks among these nuclear workers are comparable to those observed in high-dose populations, although no evidence was observed of a positive quadratic dose-response term in this study."1.34Risk of chronic myeloid and acute leukemia mortality after exposure to ionizing radiation among workers at four U.S. nuclear weapons facilities and a nuclear naval shipyard. ( Ahrenholz, SH; Anderson, JL; Burphy, JS; Couch, JR; Daniels, RD; Fleming, DA; Markey, AM; Schubauer-Berigan, MK; Tseng, CY, 2007)
"Benzene has been used in various industries as glues or solvents in Korea."1.33Occupational exposure to benzene in South Korea. ( Ahn, YS; Kang, SK; Kim, TK; Lee, JO; Lee, MY, 2005)
"National mortality rates and cancer registration (incidence) rates were used to calculate standardised mortality ratios and standardised registration ratios."1.33Cancer risks in a historical UK cohort of benzene exposed workers. ( Doll, R; Kinlen, LJ; Sorahan, T, 2005)
"Benzene exposure was associated with increases in the rates of monosomy 5 and 7 but not monosomy 1 (P < 0."1.30Increased aneusomy and long arm deletion of chromosomes 5 and 7 in the lymphocytes of Chinese workers exposed to benzene. ( Dosemeci, M; Hayes, RB; Kolachana, P; Li, G; Rothman, N; Smith, MT; Titenko-Holland, N; Wang, Y; Yin, S; Zhang, L, 1998)
"A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1."1.29An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group. ( Blot, WJ; Chow, WH; Dosemeci, M; Hayes, RB; Li, DG; Li, GL; Linet, MS; Travis, LB; Wacholder, S; Yin, SN; Zhang, ZN, 1996)
"Two young patients with secondary acute myeloid leukemia were treated with allogeneic bone marrow transplantation as first-line treatment for their disease."1.27Bone marrow transplantation performed as first-time treatment in two cases of secondary acute myeloid leukemia. ( Tricot, G; Van Hoof, A; Verwilghen, RL; Zachee, P, 1984)
"There was one case of chronic myelogenous leukemia, one of acute myeloblastic leukemia, and one of granulocytic hyperplasia among 40 CD-1 mice exposed to 300 ppm benzene; and one case of chronic myelogenous leukemia among 40 rats exposed to 100 ppm benzene."1.26Myelogenous leukemia in rodents inhaling benzene. ( Albert, RE; Bromberg, I; Goldstein, BD; Laskin, S; Nelson, N; Snyder, CA, 1982)

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-199033 (27.73)18.7374
1990's17 (14.29)18.2507
2000's16 (13.45)29.6817
2010's43 (36.13)24.3611
2020's10 (8.40)2.80

Authors

AuthorsStudies
Scholten, B1
Portengen, L2
Pronk, A1
Stierum, R1
Downward, GS1
Vlaanderen, J3
Vermeulen, R6
Zhang, H3
Pan, Z2
Ling, X2
Tan, Q2
Yuan, Q2
Qin, J1
Zhong, B1
Li, H1
Chen, J1
Chen, X1
Shi, Z1
Liu, L2
Ning, Q1
Jian, T1
Cui, S2
Shi, L1
Jian, X1
He, X2
Zhang, X1
Li, X1
Wu, M2
Zheng, D1
Xie, P1
Xie, D1
Zhao, J1
Sui, P1
Wu, B1
Chen, A1
Lu, Y1
Hou, F1
Cheng, X1
Song, J1
Huang, G1
Xing, C1
Wang, QF1
Tian, W1
Wang, TS1
Fang, Y1
Wu, HT1
Zheng, GQ1
Guo, KR1
Huang, M1
Sun, DY1
Xia, ZL1
Shallis, RM1
Weiss, JJ1
Deziel, NC1
Gore, SD1
North, CM1
Schnatter, AR4
Rooseboom, M1
Aygun Kocabas, N1
Dalzell, A1
Williams, SD1
Houot, MT1
Homère, J1
Goulard, H1
Garras, L1
Delabre, L1
Pilorget, C1
Cox, LA1
Ketelslegers, HB1
Lewis, RJ1
Janitz, AE1
Campbell, JE1
Magzamen, S1
Pate, A1
Stoner, JA1
Peck, JD1
Kerzic, PJ3
Irons, RD7
Loomis, D1
Guyton, KZ2
Grosse, Y1
El Ghissassi, F1
Bouvard, V1
Benbrahim-Tallaa, L1
Guha, N1
Vilahur, N1
Mattock, H1
Straif, K1
Gross, SA2
Paustenbach, DJ1
Fiebelkorn, S1
Meredith, C1
Raaschou-Nielsen, O1
Hvidtfeldt, UA1
Roswall, N1
Hertel, O1
Poulsen, AH1
Sørensen, M1
Linet, MS4
Gilbert, ES1
Dores, GM1
Yin, SN2
Hayes, RB6
Ji, BT1
Lan, Q4
Li, GL2
Rothman, N6
Chen, Y2
Wang, X1
Ryder, J1
Rushton, L3
Tang, G2
Glass, DC2
Mukhopadhyay, MK1
Nath, D1
Thomas, R1
Hubbard, AE2
McHale, CM3
Zhang, L5
Rappaport, SM3
Jinot, J1
Sonawane, BR1
Smith, MT8
Talibov, M1
Lehtinen-Jacks, S1
Martinsen, JI1
Kjærheim, K1
Lynge, E1
Sparén, P1
Tryggvadottir, L1
Weiderpass, E1
Kauppinen, T1
Kyyrönen, P1
Pukkala, E2
Li, K1
Jing, Y1
Yang, C1
Liu, S1
Zhao, Y1
Li, F1
Han, J1
Li, G4
Collins, JJ1
Anteau, SE1
Swaen, GM2
Bodner, KM1
Bodnar, CM1
Houot, J1
Marquant, F1
Goujon, S1
Faure, L1
Honoré, C1
Roth, MH1
Hémon, D2
Clavel, J2
Carlos-Wallace, FM1
Rader, G1
Steinmaus, C1
Wang, T1
Zhang, J1
Zou, D1
Rhomberg, L1
Goodman, J1
Tao, G1
Zu, K1
Chandalia, J1
Williams, PR1
Allen, B1
Poynter, JN1
Richardson, M1
Roesler, M1
Blair, CK1
Hirsch, B1
Nguyen, P1
Cioc, A1
Cerhan, JR1
Warlick, E1
Heederik, D1
Kromhout, H2
Kawasaki, Y1
Hirabayashi, Y2
Kaneko, T1
Kanno, J1
Kodama, Y1
Matsushima, Y1
Ogawa, Y1
Saitoh, M1
Sekita, K1
Uchida, O1
Umemura, T1
Yoon, BI1
Inoue, T2
Johnson, GT1
Harbison, SC1
McCluskey, JD1
Harbison, RD1
Bird, MG2
Greim, H1
Kaden, DA1
Rice, JM1
Snyder, R1
Leone, G1
Fianchi, L1
Pagano, L1
Voso, MT1
Pyatt, D1
Hays, S1
Hack, CE1
Haber, LT1
Maier, A1
Shulte, P1
Fowler, B1
Lotz, WG1
Savage, RE1
Khalade, A1
Jaakkola, MS1
Jaakkola, JJ1
Galbraith, D1
Paustenbach, D1
Skibola, CF2
Regev, L1
Zlotolow, R1
Brautbar, N1
Pyatt, DW1
Hays, SM1
English, C1
Cushing, CA1
Carugno, M1
Pesatori, AC1
Dioni, L1
Hoxha, M1
Bollati, V1
Albetti, B1
Byun, HM1
Bonzini, M1
Fustinoni, S1
Cocco, P1
Satta, G1
Zucca, M1
Merlo, DF1
Cipolla, M1
Bertazzi, PA1
Baccarelli, A1
Goldstein, BD5
Liu, Y1
Wu, F1
Lioy, P1
Bonaventure, A1
Goujon-Bellec, S1
Rudant, J1
Orsi, L1
Leverger, G1
Baruchel, A1
Bertrand, Y1
Nelken, B1
Pasquet, M1
Michel, G1
Sirvent, N1
Bordigoni, P1
Ducassou, S1
Rialland, X1
Zelenika, D1
Ji, Z1
Shen, M1
Guo, W1
Yin, S3
Peckham, T1
Kopstein, M1
Klein, J1
Dahlgren, J1
Vinceti, M1
Rothman, KJ1
Crespi, CM1
Sterni, A1
Cherubini, A1
Guerra, L1
Maffeis, G1
Ferretti, E1
Fabbi, S1
Teggi, S1
Consonni, D1
De Girolamo, G1
Meggiato, A1
Palazzi, G1
Paolucci, P1
Malagoli, C1
Zolghadr, F1
Sadeghizadeh, M1
Amirizadeh, N1
Hosseinkhani, S1
Nazem, S1
Kanagal-Shamanna, R1
Zhao, W1
Vadhan-Raj, S1
Nguyen, MH1
Fernandez, MH1
Medeiros, LJ1
Bueso-Ramos, CE1
Demian, C1
Martin, CJ1
Colovic, M1
Jankovic, G1
Suvajdzic, N1
Kraguljac, N1
Allan, JM1
Morgan, GJ1
Sorahan, T1
Kinlen, LJ1
Doll, R1
Kang, SK1
Lee, MY1
Kim, TK1
Lee, JO1
Ahn, YS1
Schubauer-Berigan, MK1
Daniels, RD1
Fleming, DA1
Markey, AM1
Couch, JR1
Ahrenholz, SH1
Burphy, JS1
Anderson, JL1
Tseng, CY1
Kirkeleit, J1
Riise, T1
Bråtveit, M1
Moen, BE1
Natelson, EA1
Jamall, IS1
Willhite, CC1
Rosenstock, L1
Tricot, G1
Van Hoof, A1
Zachee, P1
Verwilghen, RL1
Braier, L1
Snyder, CA1
Laskin, S1
Bromberg, I1
Albert, RE1
Nelson, N1
Crump, KS2
Hazel, BA2
Kalf, GF3
Nicolich, MJ1
Stillman, WS3
Hutt, AM1
O'Connor, A1
Niculescu, R1
Frantz, CE1
Chen, H1
Eastmond, DA1
Dosemeci, M4
Travis, LB1
Zhang, ZN1
Li, DG1
Chow, WH1
Wacholder, S1
Blot, WJ1
Raabe, GK1
Wong, O1
Wang, Y1
Kolachana, P1
Titenko-Holland, N1
Varella-Garcia, M2
Korte, JE1
Hertz-Picciotto, I1
Schulz, MR1
Ball, LM1
Duell, EJ1
Schlosser, PM1
Travis, LT1
Duarte-Davidson, R1
Courage, C1
Levy, L1
Songnian, Y1
Linet, M1
Infante, PF1
Rinsky, RA1
Wagoner, JK1
Young, RJ1
Tabershaw, IR1
Lamm, SH2
Brandt, L1
Nilsson, PG1
Mitelman, F1
Iwata, N1
Omine, M1
Tsuchiya, J1
Maekawa, T1
Forni, A3
Aksoy, M3
Erdem, S3
Dinçol, G3
Vigliani, EC2
Jakobsson, R2
Ahlbom, A2
Bellander, T2
Lundberg, I2
Lumley, M1
Barker, H1
Murray, JA1
Meijers, JM1
Walters, AS1
Wilson, R1
Byrd, DM2
Grunwald, H1
Barfield, ET1
Nilsson, RI1
Carneskog, J1
Järvholm, BG1
Nordlinder, RG1
Austin, H1
Cole, P1
McCraw, DS1
Fraumeni, JF1
Dinçol, K1
Erdogan, G1
Robustelli della Cuna, G1
Favino, A1
Biscaldi, GP1
Pollini, G1
Zini, C1
Alessandri, M1
Pugni, M1
Sinibaldi, V1
Galli, F1
Gallinelli, R1
Moreo, L1
Hartwich, G2
Schwanitz, G2
Becker, J2
Paterni, L1
Lob, M1
Buday, M1
Labant, M1
Soós, G1
Inceman, S1
Tangün, Y1

Reviews

26 reviews available for benzene and Acute Myelogenous Leukemia

ArticleYear
A clandestine culprit with critical consequences: Benzene and acute myeloid leukemia.
    Blood reviews, 2021, Volume: 47

    Topics: Adult; Benzene; Environmental Exposure; Humans; Leukemia, Myeloid, Acute; Occupational Exposure; Ris

2021
The shape of low-concentration dose-response functions for benzene: implications for human health risk assessment.
    Critical reviews in toxicology, 2021, Volume: 51, Issue:2

    Topics: Bayes Theorem; Benzene; China; Dose-Response Relationship, Drug; Environmental Exposure; Environment

2021
Shanghai Health Study (2001-2009): What was learned about benzene health effects?
    Critical reviews in toxicology, 2018, Volume: 48, Issue:3

    Topics: Benzene; Case-Control Studies; China; Environmental Exposure; Humans; Leukemia, Myeloid, Acute; Myel

2018
Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum.
    Annals of the New York Academy of Sciences, 2014, Volume: 1310

    Topics: Animals; Benzene; Cell Transformation, Neoplastic; Cytogenetic Analysis; Disease Progression; Epigen

2014
Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis.
    American journal of epidemiology, 2016, Jan-01, Volume: 183, Issue:1

    Topics: Adolescent; Benzene; Child; Child, Preschool; Environmental Exposure; Female; Humans; Infant; Infant

2016
A review of the potential association between childhood leukemia and benzene.
    Chemico-biological interactions, 2010, Mar-19, Volume: 184, Issue:1-2

    Topics: Benzene; Child; Environmental Exposure; Humans; Leukemia; Leukemia, Myeloid, Acute; Risk Factors

2010
Advances in understanding benzene health effects and susceptibility.
    Annual review of public health, 2010, Volume: 31

    Topics: Benzene; Carcinogens, Environmental; Dose-Response Relationship, Drug; Environmental Exposure; Epide

2010
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis.
    Environmental health : a global access science source, 2010, Jun-28, Volume: 9

    Topics: Benzene; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, B

2010
Occupational benzene exposure and the risk of lymphoma subtypes: a meta-analysis of cohort studies incorporating three study quality dimensions.
    Environmental health perspectives, 2011, Volume: 119, Issue:2

    Topics: Benzene; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute;

2011
Benzene and human health: A historical review and appraisal of associations with various diseases.
    Critical reviews in toxicology, 2010, Volume: 40 Suppl 2

    Topics: Benzene; Female; History, 20th Century; History, 21st Century; Humans; Leukemia, Myeloid, Acute; Lym

2010
Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature.
    Toxicology and industrial health, 2012, Volume: 28, Issue:1

    Topics: Adult; Animals; Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pai

2012
Benzene-contaminated toluene and acute myeloid leukemia: a case series and review of literature.
    Toxicology and industrial health, 2014, Volume: 30, Issue:1

    Topics: Aged; Benzene; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndrome

2014
Myelodysplastic syndrome and benzene exposure among petroleum workers: an international pooled analysis.
    Journal of the National Cancer Institute, 2012, Nov-21, Volume: 104, Issue:22

    Topics: Adult; Australia; Benzene; Canada; Case-Control Studies; Extraction and Processing Industry; Humans;

2012
Is this man's cancer related to his occupation?
    Journal of occupational and environmental medicine, 2013, Volume: 55, Issue:1

    Topics: Adult; Benzene; Biopsy, Needle; Blood Chemical Analysis; Bone Marrow; Decision Making; Disease Progr

2013
Causal models of leukaemia and lymphoma.
    IARC scientific publications, 2004, Issue:157

    Topics: Autoimmunity; Benzene; Biomarkers; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Models, Bio

2004
Benzene exposure and refractory sideroblastic erythropoiesis: is there an association?
    The American journal of the medical sciences, 2007, Volume: 334, Issue:5

    Topics: Anemia, Sideroblastic; Benzene; Environmental Pollutants; Erythropoiesis; Humans; Leukemia, Myeloid,

2007
Is benzene exposure from gasoline carcinogenic?
    Journal of environmental monitoring : JEM, 2008, Volume: 10, Issue:2

    Topics: Animals; Benzene; Carcinogens, Environmental; Gasoline; Humans; Leukemia, Myeloid, Acute; Soil Pollu

2008
The process of leukemogenesis.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Benzene; Carcinogens; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 5; Cocar

1996
Leukemia mortality by cell type in petroleum workers with potential exposure to benzene.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Benzene; Cohort Studies; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloge

1996
Needs for research on benzene metabolism and dosimetry.
    Journal of toxicology and environmental health. Part A, 2000, Volume: 61, Issue:5-6

    Topics: Anemia, Aplastic; Animals; Benzene; Dose-Response Relationship, Drug; Environmental Exposure; Humans

2000
Benzene in the environment: an assessment of the potential risks to the health of the population.
    Occupational and environmental medicine, 2001, Volume: 58, Issue:1

    Topics: Adolescent; Aged; Air Pollutants; Benzene; Carcinogens, Environmental; Child; Child, Preschool; Dose

2001
Benzene and lymphohematopoietic malignancies in humans.
    American journal of industrial medicine, 2001, Volume: 40, Issue:2

    Topics: Benzene; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Lymphoproliferative Disorders; Occ

2001
Chromosome changes and benzene exposure. A review.
    Reviews on environmental health, 1979, Volume: 3, Issue:1

    Topics: Adult; Benzene; Bone Marrow; Cell Cycle; Chromosome Aberrations; Chromosomes; Environmental Exposure

1979
Is exposure to benzene a cause of human multiple myeloma?
    Annals of the New York Academy of Sciences, 1990, Volume: 609

    Topics: Benzene; Bone Marrow; Environmental Exposure; Humans; Incidence; Leukemia, Myeloid, Acute; Multiple

1990
Consistencies and inconsistencies underlying the quantitative assessment of leukemia risk from benzene exposure.
    Environmental health perspectives, 1989, Volume: 82

    Topics: Benzene; Humans; Leukemia; Leukemia, Myeloid, Acute; Occupational Diseases; Risk

1989
Clinical epidemiology of leukemia.
    Seminars in hematology, 1969, Volume: 6, Issue:3

    Topics: Adolescent; Age Factors; Anemia, Pernicious; Benzene; Child, Preschool; Chloramphenicol; Chromosome

1969

Trials

1 trial available for benzene and Acute Myelogenous Leukemia

ArticleYear
Ambient benzene at the residence and risk for subtypes of childhood leukemia, lymphoma and CNS tumor.
    International journal of cancer, 2018, 09-15, Volume: 143, Issue:6

    Topics: Adolescent; Adult; Air Pollutants; Benzene; Case-Control Studies; Central Nervous System Neoplasms;

2018

Other Studies

92 other studies available for benzene and Acute Myelogenous Leukemia

ArticleYear
Estimation of the Exposure-Response Relation between Benzene and Acute Myeloid Leukemia by Combining Epidemiologic, Human Biomarker, and Animal Data.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2022, 04-01, Volume: 31, Issue:4

    Topics: Animals; Bayes Theorem; Benzene; Biomarkers; Humans; Leukemia, Myeloid, Acute; Occupational Exposure

2022
LINC00173 Interacts With DNMT1 to Regulate LINC00173 Expression via Promoter Methylation in Hydroquinone-Induced Malignantly Transformed TK6 Cells and Benzene-Exposed Workers.
    Toxicological sciences : an official journal of the Society of Toxicology, 2022, 05-26, Volume: 187, Issue:2

    Topics: Benzene; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Humans; Hydroquinones; Leukemia, My

2022
Tim-3 facilitates immune escape in benzene-induced acute myeloid leukemia mouse model by promoting macrophage M2 polarization.
    Ecotoxicology and environmental safety, 2023, Nov-01, Volume: 266

    Topics: Animals; Benzene; Disease Models, Animal; Hepatitis A Virus Cellular Receptor 2; Leukemia, Myeloid,

2023
Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene.
    Toxicology letters, 2020, Apr-01, Volume: 322

    Topics: Benzene; Case-Control Studies; Cell Line, Transformed; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltra

2020
Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine model.
    Leukemia, 2021, Volume: 35, Issue:2

    Topics: Animals; Benzene; Bone Marrow Cells; Cell Transformation, Neoplastic; Disease Models, Animal; Leukem

2021
Aberrant lncRNA Profiles Are Associated With Chronic Benzene Poisoning and Acute Myelocytic Leukemia.
    Journal of occupational and environmental medicine, 2020, Volume: 62, Issue:7

    Topics: Adult; Benzene; Chromosome Aberrations; Female; Gene Expression Regulation; Humans; Leukemia, Myeloi

2020
Key event-informed risk models for benzene-induced acute myeloid leukaemia.
    Toxicology letters, 2021, Apr-01, Volume: 340

    Topics: Benzene; Humans; Leukemia, Myeloid, Acute; Models, Biological; Occupational Exposure; Risk Assessmen

2021
Lifetime occupational exposure proportion estimation methods: a sensitivity analysis in the general population.
    International archives of occupational and environmental health, 2021, Volume: 94, Issue:7

    Topics: Adult; Aged; Benzene; Construction Materials; Female; Flour; France; Humans; Leukemia, Myeloid, Acut

2021
Benzene and childhood acute leukemia in Oklahoma.
    Environmental research, 2017, Volume: 158

    Topics: Adolescent; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Environm

2017
Distribution of chromosome breakpoints in benzene-exposed and unexposed AML patients.
    Environmental toxicology and pharmacology, 2017, Volume: 55

    Topics: Benzene; China; Chromosome Breakpoints; Chromosomes; Cytogenetic Analysis; Female; Humans; In Situ H

2017
Carcinogenicity of benzene.
    The Lancet. Oncology, 2017, Volume: 18, Issue:12

    Topics: Animals; Benzene; Carcinogenesis; Carcinogenicity Tests; Carcinogens, Environmental; Consensus; Dise

2017
Estimation of the Leukemia Risk in Human Populations Exposed to Benzene from Tobacco Smoke Using Epidemiological Data.
    Risk analysis : an official publication of the Society for Risk Analysis, 2018, Volume: 38, Issue:7

    Topics: Adult; Aged; Air Pollution; Benzene; Female; Humans; Leukemia, Myeloid, Acute; Life Tables; Male; Mi

2018
Benzene Exposure Response and Risk of Myeloid Neoplasms in Chinese Workers: A Multicenter Case-Cohort Study.
    Journal of the National Cancer Institute, 2019, 05-01, Volume: 111, Issue:5

    Topics: Age Factors; Benzene; China; Cohort Studies; Confidence Intervals; Humans; Leukemia, Myeloid, Acute;

2019
Acute myeloid leukemia following exposure to benzene more closely resembles de novo than therapy related-disease.
    Genes, chromosomes & cancer, 2013, Volume: 52, Issue:10

    Topics: Benzene; China; Chromosome Aberrations; Cohort Studies; Environmental Exposure; Flow Cytometry; Huma

2013
Acute myeloid and chronic lymphoid leukaemias and exposure to low-level benzene among petroleum workers.
    British journal of cancer, 2014, Feb-04, Volume: 110, Issue:3

    Topics: Australia; Benzene; Case-Control Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia,

2014
Physiologically based toxicokinetic modeling of secondary acute myelolytic leukemia.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzene; Bone Marrow Cells; Carcinogens;

2014
Characterization of changes in gene expression and biochemical pathways at low levels of benzene exposure.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Air Pollutants, Occupational; Benzene; Blood Cell Count; Cluster Analysis; Female; Gene Expression P

2014
Occupational exposure to solvents and acute myeloid leukemia: a population-based, case-control study in four Nordic countries.
    Scandinavian journal of work, environment & health, 2014, Volume: 40, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Benzene; Case-Control Studies; Female; Humans; Incidence; Leukemia,

2014
Increased leukemia-associated gene expression in benzene-exposed workers.
    Scientific reports, 2014, Jul-04, Volume: 4

    Topics: Adult; Basigin; Benzene; Carcinogens; Carcinogens, Environmental; Case-Control Studies; DNA Copy Num

2014
Lymphatic and hematopoietic cancers among benzene-exposed workers.
    Journal of occupational and environmental medicine, 2015, Volume: 57, Issue:2

    Topics: Benzene; Carcinogens; Cause of Death; Humans; Leukemia; Leukemia, Myeloid, Acute; Michigan; Myelodys

2015
Residential Proximity to Heavy-Traffic Roads, Benzene Exposure, and Childhood Leukemia-The GEOCAP Study, 2002-2007.
    American journal of epidemiology, 2015, Oct-15, Volume: 182, Issue:8

    Topics: Adolescent; Air Pollution; Benzene; Carcinogens; Case-Control Studies; Child; Child, Preschool; Fema

2015
Sudden Death Due to Cerebral Leukemic Hemorrhage in a 32-Year-Old Woman Who Had a Short-Term Benzene Exposure History.
    The American journal of forensic medicine and pathology, 2016, Volume: 37, Issue:2

    Topics: Adult; Benzene; Cerebral Hemorrhage; Death, Sudden; Diagnostic Errors; Female; Humans; Leukemia, Mye

2016
Evaluation of Acute Nonlymphocytic Leukemia and Its Subtypes With Updated Benzene Exposure and Mortality Estimates: A Lifetable Analysis of the Pliofilm Cohort.
    Journal of occupational and environmental medicine, 2016, Volume: 58, Issue:4

    Topics: Adult; Aged; Benzene; Humans; Leukemia, Myeloid, Acute; Male; Manufacturing Industry; Middle Aged; O

2016
Chemical exposures and risk of acute myeloid leukemia and myelodysplastic syndromes in a population-based study.
    International journal of cancer, 2017, Jan-01, Volume: 140, Issue:1

    Topics: Adult; Aged; Benzene; Case-Control Studies; Environmental Exposure; Female; Health Surveys; Humans;

2017
Guidelines to evaluate human observational studies for quantitative risk assessment.
    Environmental health perspectives, 2008, Volume: 116, Issue:12

    Topics: Benzene; Carcinogens; Case-Control Studies; Cohort Studies; Guidelines as Topic; Humans; Leukemia, M

2008
Benzene-induced hematopoietic neoplasms including myeloid leukemia in Trp53-deficient C57BL/6 and C3H/He mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Animals; Apoptosis; Benzene; Carcinogens; DNA Repair; Dose-Response Relationship, Drug; Gene Express

2009
Characterization of cancer risk from airborne benzene exposure.
    Regulatory toxicology and pharmacology : RTP, 2009, Volume: 55, Issue:3

    Topics: Air Pollutants; Air Pollution; Benzene; Carcinogens; Environmental Exposure; Environmental Monitorin

2009
Benzene 2009--Health effects and mechanisms of bone marrow toxicity: implications for t-AML and the mode of action framework.
    Chemico-biological interactions, 2010, Mar-19, Volume: 184, Issue:1-2

    Topics: Anemia, Aplastic; Animals; Benzene; Bone Marrow; Humans; Leukemia, Myeloid, Acute

2010
Hematopoietic neoplastic diseases develop in C3H/He and C57BL/6 mice after benzene exposure: strain differences in bone marrow tissue responses observed using microarrays.
    Chemico-biological interactions, 2010, Mar-19, Volume: 184, Issue:1-2

    Topics: Animals; Benzene; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Ge

2010
Incidence and susceptibility to therapy-related myeloid neoplasms.
    Chemico-biological interactions, 2010, Mar-19, Volume: 184, Issue:1-2

    Topics: Antineoplastic Agents; Benzene; Disease Susceptibility; Humans; Incidence; Leukemia, Myeloid, Acute;

2010
A Bayesian network model for biomarker-based dose response.
    Risk analysis : an official publication of the Society for Risk Analysis, 2010, Volume: 30, Issue:7

    Topics: Air Pollutants; Bayes Theorem; Benzene; Biomarkers; Dose-Response Relationship, Drug; Humans; Leukem

2010
Benzene 2009-Health effects and mechanisms of bone marrow toxicity: implications for t-AML and the mode of action framework. Proceedings of a meeting. September 7-12, 2009. Munich, Germany.
    Chemico-biological interactions, 2010, Mar-19, Volume: 184, Issue:1-2

    Topics: Animals; Benzene; Bone Marrow; Bone Marrow Diseases; Humans; Leukemia, Myeloid, Acute

2010
Benzene, the exposome and future investigations of leukemia etiology.
    Chemico-biological interactions, 2011, Jun-30, Volume: 192, Issue:1-2

    Topics: Benzene; Carcinogens; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2011
United States Voluntary Children's Chemical Evaluation Program (VCCEP) risk assessment for children exposed to benzene.
    Toxicology mechanisms and methods, 2012, Volume: 22, Issue:2

    Topics: Benzene; Child; Hematopoietic System; Humans; Leukemia, Myeloid, Acute; Neoplasms; Reference Values;

2012
Increased mitochondrial DNA copy number in occupations associated with low-dose benzene exposure.
    Environmental health perspectives, 2012, Volume: 120, Issue:2

    Topics: Adult; Air Pollutants, Occupational; Benzene; Biomarkers; Cities; Cross-Sectional Studies; Cyclin-De

2012
Comparison of the effects of the US Clean Air Act and of smoking prevention and cessation efforts on the risk of acute myelogenous leukemia.
    American journal of public health, 2011, Volume: 101, Issue:12

    Topics: Air Pollutants; Air Pollution; Benzene; Environmental Exposure; Humans; Leukemia, Myeloid, Acute; Ri

2011
Maternal smoking during pregnancy, genetic polymorphisms of metabolic enzymes, and childhood acute leukemia: the ESCALE study (SFCE).
    Cancer causes & control : CCC, 2012, Volume: 23, Issue:2

    Topics: Adolescent; Alleles; Benzene; Case-Control Studies; Child; Child, Preschool; Cytochrome P-450 CYP1A1

2012
Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers.
    Leukemia, 2012, Volume: 26, Issue:12

    Topics: Adult; Aneuploidy; Benzene; Case-Control Studies; Chromosome Deletion; Chromosomes, Human, Pair 7; C

2012
Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population.
    European journal of epidemiology, 2012, Volume: 27, Issue:10

    Topics: Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Fema

2012
How benzene and its metabolites affect human marrow derived mesenchymal stem cells.
    Toxicology letters, 2012, Oct-17, Volume: 214, Issue:2

    Topics: Apoptosis; Benzene; Benzoquinones; Calcium-Binding Proteins; Caspases; Cell Survival; Chemokine CXCL

2012
Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv(16)(p13.1q22); CBFβ-MYH11.
    International journal of environmental research and public health, 2012, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Aged; Benzene; Child; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Female; H

2012
Cytologically distinct acute leukemia in sibs exposed to the same leukemogen.
    Haematologia, 1996, Volume: 27, Issue:4

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzene; Cyclophospham

1996
Cancer risks in a historical UK cohort of benzene exposed workers.
    Occupational and environmental medicine, 2005, Volume: 62, Issue:4

    Topics: Benzene; Carcinogens, Environmental; Cause of Death; Cohort Studies; England; Female; Humans; Incide

2005
Occupational exposure to benzene in South Korea.
    Chemico-biological interactions, 2005, May-30, Volume: 153-154

    Topics: Adult; Air Pollutants, Occupational; Benzene; Biomarkers; Environmental Monitoring; Epidemiological

2005
Risk of chronic myeloid and acute leukemia mortality after exposure to ionizing radiation among workers at four U.S. nuclear weapons facilities and a nuclear naval shipyard.
    Radiation research, 2007, Volume: 167, Issue:2

    Topics: Aged; Benzene; Cohort Studies; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leu

2007
Increased risk of acute myelogenous leukemia and multiple myeloma in a historical cohort of upstream petroleum workers exposed to crude oil.
    Cancer causes & control : CCC, 2008, Volume: 19, Issue:1

    Topics: Benzene; Cohort Studies; Humans; Leukemia, Myeloid, Acute; Multiple Myeloma; Norway; Occupational Di

2008
Occupational cancer: clinical interpretation and application of scientific evidence.
    Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:3

    Topics: Aged; Air Pollutants, Occupational; Asbestos; Benzene; Epidemiologic Methods; Humans; Leukemia, Myel

1984
Bone marrow transplantation performed as first-time treatment in two cases of secondary acute myeloid leukemia.
    Leukemia research, 1984, Volume: 8, Issue:1

    Topics: Benzene; Bone Marrow Transplantation; Combined Modality Therapy; Humans; Leukemia, Myeloid, Acute; R

1984
Benzene is still with us.
    American journal of industrial medicine, 1983, Volume: 4, Issue:5

    Topics: Benzene; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Occupational Diseases;

1983
An hypothesis for the induction of leukemia by benzene.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1983, Volume: 6

    Topics: Benzene; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Occupational D

1983
Myelogenous leukemia in rodents inhaling benzene.
    Toxicology letters, 1982, Volume: 13, Issue:3-4

    Topics: Animals; Benzene; Carcinogens; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute;

1982
Risk of benzene-induced leukemia: a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates.
    Journal of toxicology and environmental health, 1994, Volume: 42, Issue:2

    Topics: Adult; Aged; Benzene; Cohort Studies; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; L

1994
Induction of granulocytic differentiation in myeloblasts by hydroquinone, a metabolite of benzene, involves the leukotriene D4 receptor.
    Receptors & signal transduction, 1996, Volume: 6, Issue:1

    Topics: Animals; Benzene; Cell Differentiation; Cell Line; Granulocyte Colony-Stimulating Factor; Granulocyt

1996
Determination of leukemogenic benzene exposure concentrations: refined analyses of the Pliofilm cohort.
    Risk analysis : an official publication of the Society for Risk Analysis, 1996, Volume: 16, Issue:6

    Topics: Benzene; Carcinogens; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Le

1996
Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Animals; Benzene; Benzoquinones; Carcinogens; DNA Damage; DNA, Kinetoplast; Enzyme Inhibitors; Human

1996
Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Animals; Arachidonate 5-Lipoxygenase; Benzene; Carcinogens; Cell Differentiation; Granulocytes; HL-6

1996
Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Animals; Benzene; Carcinogens; Chromosome Aberrations; Enzyme Inhibitors; Humans; In Vitro Technique

1996
An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Anemia, Aplastic; Benzene; Carcinogens; China; Cohort Studies; Female; Humans; Leukemia; Leukemia, M

1996
Risk of benzene-induced leukemia predicted from the Pliofilm cohort.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Benzene; Cohort Studies; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Leukemia; Leuk

1996
Increased aneusomy and long arm deletion of chromosomes 5 and 7 in the lymphocytes of Chinese workers exposed to benzene.
    Carcinogenesis, 1998, Volume: 19, Issue:11

    Topics: Adult; Benzene; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 5; Chromos

1998
The benzene metabolite, hydroquinone, selectively induces 5q31- and -7 in human CD34+CD19- bone marrow cells.
    Experimental hematology, 2000, Volume: 28, Issue:2

    Topics: Benzene; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Hematop

2000
The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:3-4

    Topics: Benzene; Catechols; Cell Transformation, Neoplastic; Chromosome Deletion; Chromosomes, Human, Pair 5

1999
The contribution of benzene to smoking-induced leukemia.
    Environmental health perspectives, 2000, Volume: 108, Issue:4

    Topics: Adolescent; Adult; Aged; Animals; Benzene; Child; Child, Preschool; Cohort Studies; Dogs; Female; Hu

2000
Benzene and lymphohematopoietic malignancies in China.
    Journal of toxicology and environmental health. Part A, 2000, Volume: 61, Issue:5-6

    Topics: Adult; Anemia, Aplastic; Benzene; Carcinogens; China; Cohort Studies; Dose-Response Relationship, Dr

2000
Leukaemia in benzene workers.
    Lancet (London, England), 1977, Jul-09, Volume: 2, Issue:8028

    Topics: Adult; Aged; Benzene; Chemical Industry; Follow-Up Studies; Humans; Leukemia; Leukemia, Myeloid; Leu

1977
Benzene and leukaemia.
    Lancet (London, England), 1977, Oct-22, Volume: 2, Issue:8043

    Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Chemical Industry; Humans; Leukemia; Leukemia

1977
Non-industrial exposure to benzene as leukaemogenic risk factor.
    Lancet (London, England), 1977, Nov-19, Volume: 2, Issue:8047

    Topics: Acute Disease; Adolescent; Adult; Benzene; Environmental Exposure; Female; Humans; Leukemia; Leukemi

1977
[A case with aplastic anemia presumably related to benzene exposure terminating in acute myelogenous leukemia associated with myelofibrosis (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1978, Volume: 19, Issue:9

    Topics: Adult; Anemia, Aplastic; Benzene; Humans; Leukemia, Myeloid, Acute; Male; Occupational Diseases; Pri

1978
Types of leukemia in chronic benzene poisoning. A study in thirty-four patients.
    Acta haematologica, 1976, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Benzene; Environmental Exposure; Humans; Leukemia; Leukemia, Lymphoid; Leukemia,

1976
Leukemia associated with benzene exposure.
    Annals of the New York Academy of Sciences, 1976, Volume: 271

    Topics: Acute Disease; Adult; Aged; Air Pollutants, Occupational; Anemia; Anemia, Aplastic; Benzene; Carcino

1976
[Follow-up of leukemia in drivers is of interest].
    Lakartidningen, 1992, Apr-29, Volume: 89, Issue:18

    Topics: Automobile Driving; Benzene; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Occupational Expos

1992
[Strongly increased risk of acute myeloid leukemia among gasoline service station workers].
    Lakartidningen, 1992, Jan-15, Volume: 89, Issue:3

    Topics: Adult; Aged; Benzene; Gasoline; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Occupational Ex

1992
Benzene in petrol.
    Lancet (London, England), 1990, Nov-24, Volume: 336, Issue:8726

    Topics: Benzene; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair

1990
Risk assessment of leukaemia and occupational exposure to benzene.
    British journal of industrial medicine, 1989, Volume: 46, Issue:12

    Topics: Benzene; Humans; Leukemia, Myeloid, Acute; Male; Occupational Diseases; Risk Factors

1989
Uncertainty in the estimation of benzene risks: application of an uncertainty taxonomy to risk assessments based on an epidemiology study of rubber hydrochloride workers.
    Environmental health perspectives, 1989, Volume: 82

    Topics: Benzene; Epidemiologic Methods; Humans; Leukemia, Myeloid, Acute; Middle Aged; Occupational Diseases

1989
Acute nonlymphatic leukemia among deck officers on coastal tankers: a report of two cases.
    American journal of industrial medicine, 1988, Volume: 14, Issue:6

    Topics: Adult; Aged; Benzene; Humans; Leukemia, Myeloid, Acute; Male; Occupational Diseases; Risk Factors; S

1988
Biological and ambient monitoring of benzene in the workplace.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1986, Volume: 28, Issue:10

    Topics: Air Pollutants, Occupational; Anemia, Aplastic; Benzene; Blood Cell Count; Humans; Leukemia, Myeloid

1986
A case-control study of leukemia at an oil refinery.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1986, Volume: 28, Issue:11

    Topics: Benzene; Follow-Up Studies; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Occupational Diseases;

1986
Acute leukemia due to chronic exposure to benzene.
    The American journal of medicine, 1972, Volume: 52, Issue:2

    Topics: Adult; Anemia, Aplastic; Benzene; Environmental Exposure; Humans; Leukemia, Monocytic, Acute; Leukem

1972
Acute leukaemia in two generations following chronic exposure to benzene.
    Human heredity, 1974, Volume: 24, Issue:1

    Topics: Adult; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Leukemia, Lymphoid; Leukemia

1974
[Transformation into acute leukemia of a case of involutive myelopathy due to benzene poisoning].
    Haematologica, 1972, Volume: 57, Issue:1

    Topics: Anemia, Aplastic; Benzene; Chromosome Aberrations; Humans; Karyotyping; Leukemia, Myeloid, Acute; Ma

1972
[Pseudo-Pelger leukocyte anomaly in a case of benzene hemopathy with acute terminal leukemia].
    Haematologica, 1967, Volume: 52, Issue:3

    Topics: Adult; Benzene; Female; Humans; Leukemia, Myeloid, Acute; Leukocytes; Primary Myelofibrosis

1967
[Development of involutive benzol myelopathy into acute leukemia].
    Haematologica, 1971, Volume: 56, Issue:1

    Topics: Benzene; Bone Marrow; Bone Marrow Diseases; Bone Marrow Examination; Environmental Exposure; Humans;

1971
[Acute paramyeloblastic leukosis due to chronic benzene poisoning in a girl student of an art school of mosaics].
    La Medicina del lavoro, 1966, Volume: 57, Issue:4

    Topics: Adolescent; Benzene; Female; Humans; Leukemia, Myeloid, Acute; Occupational Diseases

1966
Cytogenetic studies in a case of benzene leukaemia.
    European journal of cancer, 1967, Volume: 3, Issue:4

    Topics: Adult; Benzene; Chromosomes; Environmental Exposure; Female; Humans; Leukemia, Myeloid, Acute

1967
[Chromosome aberration in a benzol leukemia].
    Deutsche medizinische Wochenschrift (1946), 1969, Jun-06, Volume: 94, Issue:23

    Topics: Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Karyotyping; Leukemia, Myeloid, Acu

1969
[Leukemias and lymph gland tumors due to benzene: etiological and general pathological aspects].
    Minerva medica, 1969, May-16, Volume: 60, Issue:39

    Topics: Benzene; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; L

1969
Benzene, chromosome changes and leukemia.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1969, Volume: 11, Issue:3

    Topics: Benzene; Chromosomes; Humans; Leukemia, Myeloid, Acute

1969
Chromosome anomalies in a case of benzene leukaemia.
    German medical monthly, 1969, Volume: 14, Issue:9

    Topics: Benzene; Chromosome Aberrations; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; M

1969
[Etiological role of benzene in 2 supposedly cryptogenetic fatal hemopathies].
    Schweizerische medizinische Wochenschrift, 1969, Aug-16, Volume: 99, Issue:33

    Topics: Adult; Benzene; Carcinogens; Environmental Exposure; Female; Humans; Leukemia; Leukemia, Myeloid, Ac

1969
[Acute myelosis caused by benzol-induced panmyelopathy].
    Orvosi hetilap, 1971, Oct-03, Volume: 112, Issue:40

    Topics: Adult; Air Pollution; Benzene; Bone Marrow; Bone Marrow Diseases; Bone Marrow Examination; Chemical

1971
[Impaired platelet-collagen reaction in a case of acute myeloblastic leukemia due to chronic benzene intoxication].
    Turk Tip Cemiyeti mecmuasi, 1969, Volume: 35, Issue:7

    Topics: Adult; Benzene; Blood Platelet Disorders; Environmental Exposure; Humans; Leukemia, Myeloid, Acute;

1969