Page last updated: 2024-10-16

benzene and Acute Lymphoid Leukemia

benzene has been researched along with Acute Lymphoid Leukemia in 25 studies

Research Excerpts

ExcerptRelevanceReference
" However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL) have not been systematically assessed."8.90Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies. ( Bai, Y; Bi, Y; Li, Z; Wang, H; Zhang, S; Zhou, Y; Zhu, J, 2014)
"A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous."8.86Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010)
"Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia."7.78Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012)
"The meta-SMR for acute myeloid leukemia was 0."6.39Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996)
" However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL) have not been systematically assessed."4.90Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies. ( Bai, Y; Bi, Y; Li, Z; Wang, H; Zhang, S; Zhou, Y; Zhu, J, 2014)
"A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous."4.86Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. ( Jaakkola, JJ; Jaakkola, MS; Khalade, A; Pukkala, E, 2010)
"We aimed to evaluate the impact of the EPA's Mobile Source Air Toxics rules (MSAT), which targeted benzene emissions, on childhood and young adult leukemia and lymphoma incidence in Alaska."4.31Mobile Source Benzene Regulations and Risk of Childhood and Young Adult Hematologic Cancers in Alaska: A Quasi-experimental Study. ( Frazier, AL; Laden, F; Nethery, RC; Vega, S, 2023)
"Petrol stations emit benzene and other contaminants that have been associated with an increased risk of childhood leukemia."4.31Residential proximity to petrol stations and risk of childhood leukemia. ( Bellelli, A; Cellini, M; Costanzini, S; Filippini, T; Malagoli, C; Malavolti, M; Palazzi, G; Teggi, S; Vinceti, M; Wise, LA, 2023)
"In a case-cohort study with follow-up of 110 631 Chinese workers during 1972-1999, we evaluated benzene exposure-response for non-Hodgkin lymphoma (NHL), lymphoid leukemias (LL), acute lymphocytic leukemia (ALL), and total lymphoid neoplasms (LN)."3.96Benzene exposure-response and risk of lymphoid neoplasms in Chinese workers: A multicenter case-cohort study. ( Dores, GM; Gilbert, ES; Hayes, RB; Ji, BT; Lan, Q; Li, GL; Linet, MS; Portengen, L; Rothman, N; Vermeulen, R; Yin, SN, 2020)
"Benzene, a recognized occupational leukemogen in adults, has been hypothesized to also increase the risk of childhood leukemia."3.78Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population. ( Cherubini, A; Consonni, D; Crespi, CM; De Girolamo, G; Fabbi, S; Ferretti, E; Guerra, L; Maffeis, G; Malagoli, C; Meggiato, A; Palazzi, G; Paolucci, P; Rothman, KJ; Sterni, A; Teggi, S; Vinceti, M, 2012)
"Benzene is an established cause of leukemia in adults, especially acute non-lymphocytic leukemia (ANLL)."3.69Environmental exposure to gasoline and leukemia in children and young adults--an ecology study. ( Järvholm, B; Nordlinder, R, 1997)
"Benzene is an established cause of adult leukemia, but whether it is associated with childhood leukemia remains unclear."2.53Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis. ( Carlos-Wallace, FM; Rader, G; Smith, MT; Steinmaus, C; Zhang, L, 2016)
"Discussion and synthesis of the animal cancer studies and mechanistic data related to specific cancers also were limited."2.47The IARC october 2009 evaluation of benzene carcinogenicity was incomplete and needs to be reconsidered. ( Infante, PF, 2011)
"The meta-SMR for acute myeloid leukemia was 0."2.39Leukemia mortality by cell type in petroleum workers with potential exposure to benzene. ( Raabe, GK; Wong, O, 1996)
"Benzene was largely banned from Danish workplaces after 1975, thus this case-control study focused on the immediately prior years."1.51Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study. ( Contreras, ZA; Hansen, J; He, D; Heck, JE; Olsen, J; Ritz, B, 2019)
"Benzene exposure was assessed through self-reported exposure to "gasoline or exhaust"."1.48Maternal exposure to gasoline and exhaust increases the risk of childhood leukaemia in offspring - a prospective study in the Norwegian Mother and Child Cohort Study. ( Baccarelli, A; Bjørge, T; Bråtveit, M; Christiani, DC; Gjertsen, BT; Hollund, BE; Kirkeleit, J; Mattioli, S; Riise, T, 2018)
"Etoposide was used as a positive control as it is a topo II poison and established human leukemogen that has previously been shown to induce END in Chinese hamster ovary cells."1.35The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells. ( Guo, W; Ji, Z; McHale, CM; Smith, MT; Zhang, L, 2009)
"This study investigated benzene-induced neoplasia in CBA/Ca mice, with special emphasis on hematopoietic tissues."1.29Carcinogenicity of inhaled benzene in CBA mice. ( Everitt, JI; Farris, GM; Irons, RD; Popp, JA, 1993)
"All cancers, acute lymphocytic leukemia (ALL), and brain cancer were examined in relation to parental occupation during the year prior to the birth of the child."1.28Use of a job-exposure matrix to evaluate parental occupation and childhood cancer. ( Feingold, L; John, EM; Savitz, DA, 1992)
"A case of early B t(4;11)(q21;q23) acute lymphoblastic leukemia (ALL) with low white blood cell (WBC) count, without splenomegaly, short survival time, in a patient previously exposed to benzol is presented."1.28Acute lymphoblastic leukemia with t(4;11) in a patient previously exposed to a carcinogen. ( Caballín, MR; Coll, MD; Egozcue, J; Solé, F; Woessner, S, 1990)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (24.00)18.2507
2000's4 (16.00)29.6817
2010's12 (48.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Nethery, RC1
Vega, S1
Frazier, AL1
Laden, F1
Malavolti, M1
Malagoli, C2
Filippini, T1
Wise, LA1
Bellelli, A1
Palazzi, G2
Cellini, M1
Costanzini, S1
Teggi, S2
Vinceti, M2
Linet, MS1
Gilbert, ES1
Vermeulen, R1
Dores, GM1
Yin, SN1
Portengen, L1
Hayes, RB1
Ji, BT1
Lan, Q1
Li, GL1
Rothman, N1
Janitz, AE1
Campbell, JE1
Magzamen, S1
Pate, A1
Stoner, JA1
Peck, JD1
Raaschou-Nielsen, O1
Hvidtfeldt, UA1
Roswall, N1
Hertel, O1
Poulsen, AH1
Sørensen, M1
Kirkeleit, J1
Riise, T1
Bjørge, T1
Christiani, DC1
Bråtveit, M1
Baccarelli, A1
Mattioli, S1
Hollund, BE1
Gjertsen, BT1
Heck, JE1
He, D1
Contreras, ZA1
Ritz, B1
Olsen, J1
Hansen, J1
Zhou, Y1
Zhang, S1
Li, Z1
Zhu, J1
Bi, Y1
Bai, Y1
Wang, H1
Houot, J1
Marquant, F1
Goujon, S1
Faure, L1
Honoré, C1
Roth, MH1
Hémon, D2
Clavel, J2
Carlos-Wallace, FM1
Zhang, L2
Smith, MT3
Rader, G1
Steinmaus, C1
Symanski, E1
Tee Lewis, PG1
Chen, TY1
Chan, W1
Lai, D1
Ma, X1
Ji, Z1
Guo, W1
McHale, CM1
Khalade, A1
Jaakkola, MS1
Pukkala, E1
Jaakkola, JJ1
Cogliano, VJ1
Baan, R1
Straif, K1
Infante, PF1
Rothman, KJ1
Crespi, CM1
Sterni, A1
Cherubini, A1
Guerra, L1
Maffeis, G1
Ferretti, E1
Fabbi, S1
Consonni, D1
De Girolamo, G1
Meggiato, A1
Paolucci, P1
Skibola, CF1
Allan, JM1
Morgan, GJ1
Steffen, C1
Auclerc, MF1
Auvrignon, A1
Baruchel, A1
Kebaili, K1
Lambilliotte, A1
Leverger, G1
Sommelet, D1
Vilmer, E1
Infante-Rivard, C1
Vermunt, JK1
Weinberg, CR1
Farris, GM1
Everitt, JI1
Irons, RD1
Popp, JA1
Raabe, GK1
Wong, O1
Rushton, L1
Romaniuk, H1
Nordlinder, R1
Järvholm, B1
Feingold, L1
Savitz, DA1
John, EM1
Solé, F1
Caballín, MR1
Coll, MD1
Woessner, S1
Egozcue, J1

Reviews

7 reviews available for benzene and Acute Lymphoid Leukemia

ArticleYear
Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Benzene; Case-Control Studies; Cohort Studies; Female; Humans; Maternal Exposure; Odds Ratio; Precur

2014
Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis.
    American journal of epidemiology, 2016, Jan-01, Volume: 183, Issue:1

    Topics: Adolescent; Benzene; Child; Child, Preschool; Environmental Exposure; Female; Humans; Infant; Infant

2016
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis.
    Environmental health : a global access science source, 2010, Jun-28, Volume: 9

    Topics: Benzene; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, B

2010
Updating IARC's carcinogenicity assessment of benzene.
    American journal of industrial medicine, 2011, Volume: 54, Issue:2

    Topics: Benzene; Carcinogens, Environmental; Congresses as Topic; Humans; International Agencies; Internatio

2011
The IARC october 2009 evaluation of benzene carcinogenicity was incomplete and needs to be reconsidered.
    American journal of industrial medicine, 2011, Volume: 54, Issue:2

    Topics: Benzene; Carcinogens, Environmental; Congresses as Topic; Humans; International Agencies; Internatio

2011
Causal models of leukaemia and lymphoma.
    IARC scientific publications, 2004, Issue:157

    Topics: Autoimmunity; Benzene; Biomarkers; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Models, Bio

2004
Leukemia mortality by cell type in petroleum workers with potential exposure to benzene.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Benzene; Cohort Studies; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloge

1996

Trials

1 trial available for benzene and Acute Lymphoid Leukemia

ArticleYear
Ambient benzene at the residence and risk for subtypes of childhood leukemia, lymphoma and CNS tumor.
    International journal of cancer, 2018, 09-15, Volume: 143, Issue:6

    Topics: Adolescent; Adult; Air Pollutants; Benzene; Case-Control Studies; Central Nervous System Neoplasms;

2018

Other Studies

17 other studies available for benzene and Acute Lymphoid Leukemia

ArticleYear
Mobile Source Benzene Regulations and Risk of Childhood and Young Adult Hematologic Cancers in Alaska: A Quasi-experimental Study.
    Epidemiology (Cambridge, Mass.), 2023, 05-01, Volume: 34, Issue:3

    Topics: Air Pollutants; Alaska; Benzene; Child; Hematologic Neoplasms; Humans; Lymphoma; Precursor Cell Lymp

2023
Residential proximity to petrol stations and risk of childhood leukemia.
    European journal of epidemiology, 2023, Volume: 38, Issue:7

    Topics: Adolescent; Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Gasoline; Humans

2023
Benzene exposure-response and risk of lymphoid neoplasms in Chinese workers: A multicenter case-cohort study.
    American journal of industrial medicine, 2020, Volume: 63, Issue:9

    Topics: Adolescent; Adult; Benzene; China; Cohort Studies; Female; Follow-Up Studies; Humans; Leukemia, Lymp

2020
Benzene and childhood acute leukemia in Oklahoma.
    Environmental research, 2017, Volume: 158

    Topics: Adolescent; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Environm

2017
Maternal exposure to gasoline and exhaust increases the risk of childhood leukaemia in offspring - a prospective study in the Norwegian Mother and Child Cohort Study.
    British journal of cancer, 2018, Volume: 119, Issue:8

    Topics: Benzene; Female; Gasoline; Humans; Male; Maternal Exposure; Norway; Precursor Cell Lymphoblastic Leu

2018
Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study.
    Occupational and environmental medicine, 2019, Volume: 76, Issue:8

    Topics: Adolescent; Adult; Benzene; Case-Control Studies; Child; Child, Preschool; Denmark; Female; Humans;

2019
Residential Proximity to Heavy-Traffic Roads, Benzene Exposure, and Childhood Leukemia-The GEOCAP Study, 2002-2007.
    American journal of epidemiology, 2015, Oct-15, Volume: 182, Issue:8

    Topics: Adolescent; Air Pollution; Benzene; Carcinogens; Case-Control Studies; Child; Child, Preschool; Fema

2015
Air toxics and early childhood acute lymphocytic leukemia in Texas, a population based case control study.
    Environmental health : a global access science source, 2016, 06-14, Volume: 15, Issue:1

    Topics: Adult; Air Pollutants; Benzene; Butadienes; Case-Control Studies; Child, Preschool; Environmental Mo

2016
The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells.
    Mutagenesis, 2009, Volume: 24, Issue:4

    Topics: Benzene; Cell Line, Tumor; Chromosomes; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gen

2009
Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control study in an Italian population.
    European journal of epidemiology, 2012, Volume: 27, Issue:10

    Topics: Air Pollutants; Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Fema

2012
Acute childhood leukaemia and environmental exposure to potential sources of benzene and other hydrocarbons; a case-control study.
    Occupational and environmental medicine, 2004, Volume: 61, Issue:9

    Topics: Benzene; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Female; France; Huma

2004
Excess transmission of the NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia.
    American journal of epidemiology, 2007, Jun-01, Volume: 165, Issue:11

    Topics: Adolescent; Benzene; Child; Child, Preschool; Family Health; Female; Humans; Infant; Infant, Newborn

2007
Carcinogenicity of inhaled benzene in CBA mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1993, Volume: 20, Issue:4

    Topics: Administration, Inhalation; Animals; Benzene; Blood Cell Count; Bone Marrow; Carcinogenicity Tests;

1993
A case-control study to investigate the risk of leukaemia associated with exposure to benzene in petroleum marketing and distribution workers in the United Kingdom.
    Occupational and environmental medicine, 1997, Volume: 54, Issue:3

    Topics: Benzene; Case-Control Studies; Cohort Studies; Death Certificates; Humans; Leukemia; Leukemia, Lymph

1997
Environmental exposure to gasoline and leukemia in children and young adults--an ecology study.
    International archives of occupational and environmental health, 1997, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Automobiles; Benzene; Child; Child, Preschool; Environmental Exposure; Female; Ga

1997
Use of a job-exposure matrix to evaluate parental occupation and childhood cancer.
    Cancer causes & control : CCC, 1992, Volume: 3, Issue:2

    Topics: Adolescent; Benzene; Beryllium; Brain Neoplasms; Carcinogens; Child; Child, Preschool; Creosote; Fem

1992
Acute lymphoblastic leukemia with t(4;11) in a patient previously exposed to a carcinogen.
    Cancer genetics and cytogenetics, 1990, Oct-01, Volume: 49, Issue:1

    Topics: Benzene; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Female; Genetic Markers; Humans; K

1990