benzene has been researched along with Abnormalities, Autosome in 171 studies
Excerpt | Relevance | Reference |
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"We investigated whether occupational exposures to benzene near 1 ppm induce aneuploidy in sperm." | 7.76 | Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy. ( Eskenazi, B; Kurtovich, E; Li, G; Marchetti, F; Rappaport, S; Schmid, TE; Waidyanatha, S; Weldon, RH; Wyrobek, AJ; Xing, C; Young, S; Zhang, L, 2010) |
"Epidemiological studies show that benzene exposure is associated with an increased incidence of leukemia and perhaps lymphoma." | 7.74 | Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Li, G; Lu, W; Rothman, N; Smith, MT; Yang, W; Yin, S; Zhang, L, 2007) |
"To compare the extent of genetic damages in somatic and germ cells from patients of benzene poisoning, silicosis and gas poisoning, which may provide clues for protection and reproductive healthcare." | 7.74 | [Genetic damages in somatic and germ cells from patients of benzene poisoning, asbestosis and gas poisoning.]. ( Li, L; Meng, XL; Wen, T; Wu, B; You, T; Zhang, H, 2007) |
"Leukemia is the most common cancer in children." | 5.30 | Biomarkers of leukemia risk: benzene as a model. ( Smith, MT; Zhang, L, 1998) |
"Benzene is a human carcinogen present naturally in petroleum and gasoline." | 5.30 | Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells. ( Barrett, JC; Hayashi, N; Huff, J; Maizumi, H; Tsutsui, T, 1997) |
"Benzene has been known to be a bone marrow poison for almost a century." | 5.27 | Benzene: epidemiologic observations of leukemia by cell type and adverse health effects associated with low-level exposure. ( Infante, PF; White, MC, 1983) |
"Benzene is an established cause of human leukemia that is thought to act by producing chromosomal aberrations and altered in cell differentiation." | 4.81 | The nature of chromosomal aberrations detected in humans exposed to benzene. ( Eastmond, DA; Smith, MT; Zhang, L, 2002) |
" Over the last half-century a predominant paradigm has emerged to describe leukemia developing secondary to alkylating drug therapy or exposure to benzene in which progressive dysplastic changes, accompanied by a distinct pattern of clonal cytogenetic abnormalities, give rise to acute myelogenous leukemia." | 4.79 | The process of leukemogenesis. ( Irons, RD; Stillman, WS, 1996) |
"Production usage and potential occupational exposure to benzene are described in this review, as are selected, relevant reports presenting evidence evidence implicating benzene as a causative factor in leukemia, particularly acute myelogenous leukemia, pancytopenia (including aplastic anemia) and chromosomal aberrations." | 4.75 | Benzene--attempts to establish a lower exposure standard in the United States. A review. ( Zenz, C, 1978) |
"We investigated whether occupational exposures to benzene near 1 ppm induce aneuploidy in sperm." | 3.76 | Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy. ( Eskenazi, B; Kurtovich, E; Li, G; Marchetti, F; Rappaport, S; Schmid, TE; Waidyanatha, S; Weldon, RH; Wyrobek, AJ; Xing, C; Young, S; Zhang, L, 2010) |
"To compare the extent of genetic damages in somatic and germ cells from patients of benzene poisoning, silicosis and gas poisoning, which may provide clues for protection and reproductive healthcare." | 3.74 | [Genetic damages in somatic and germ cells from patients of benzene poisoning, asbestosis and gas poisoning.]. ( Li, L; Meng, XL; Wen, T; Wu, B; You, T; Zhang, H, 2007) |
"Epidemiological studies show that benzene exposure is associated with an increased incidence of leukemia and perhaps lymphoma." | 3.74 | Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers. ( Guo, W; Hayes, RB; Hubbard, AE; Li, G; Lu, W; Rothman, N; Smith, MT; Yang, W; Yin, S; Zhang, L, 2007) |
"Exposed to benzene at higher concentration may induce increase in aneuploidy frequency of sperm sex chromosome in exposed workers." | 3.70 | [Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization]. ( Deng, L; Liu, S; Tang, G; Zhang, Q; Zheng, L, 2000) |
"Benzene is a clastogenic and carcinogenic agent that induces acute myelogenous leukemia in humans and multiple of tumors in animals." | 3.69 | Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites. ( Chen, H; Eastmond, DA; Frantz, CE, 1996) |
"Hydroquinone is a phenolic metabolite of benzene, a known human carcinogen." | 2.48 | Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature. ( Brautbar, N; Regev, L; Wu, M; Zlotolow, R, 2012) |
" It is believed that benzene exerts its adverse effects by metabolic activation to toxic metabolites." | 2.44 | Benzene's toxicity: a consolidated short review of human and animal studies. ( Ahmad Khan, H, 2007) |
"Its latency, cytogenetic aberrations, and clinical features are thought similar to, or identical with, AML resulting from the use of modern day cytotoxic agents for chemotherapy and immunotherapy." | 2.44 | Benzene-induced acute myeloid leukemia: a clinician's perspective. ( Natelson, EA, 2007) |
"The primary aim of cancer prevention is to stop carcinogens from entering the body." | 2.44 | [Theory and practice of primary cancer prevention]. ( Tompa, A, 2007) |
"It has been shown, that benzene causes chromosomal aberrations, sister chromatid exchanges and micronuclei in lymphocytes of exposed workers." | 2.42 | Chromosomal aberrations in humans induced by benzene. ( Dianovskỳ, J; Holecková, B; Piesová, E; Sivikova, K, 2004) |
" There is need to better define the lower end of the dose-response curve for benzene as a human leukemogen." | 2.38 | The toxicology of benzene. ( Goldstein, BD; Snyder, R; Witz, G, 1993) |
" In one study, we observed unusual dose-response in lymphocyte chromosome aberration frequencies after exposure of mice to low doses of a chemical mixture (benzene, chloroprene, epichlorohydrin, and xylene)." | 2.38 | Cytogenetic assays in genotoxic studies: somatic cell effects of benzene and germinal cell effects of dibromochloropropane. ( Au, WW; Cantelli-Forti, G; Hrelia, P; Legator, MS, 1990) |
"Benzene exposure can induce chromosome aberrations in somatic cells (lymphocytes and bone marrow cells) of man and of experimental animals in vivo, as well as in some in vitro systems." | 2.36 | Chromosome changes and benzene exposure. A review. ( Forni, A, 1979) |
"Benzene is a recognized hematotoxin and leukemogen; however, its mechanism of action in humans remain unclear." | 1.62 | Metabolome-wide association study of occupational exposure to benzene. ( Hu, W; Jones, DP; Lan, Q; Rahman, M; Rappaport, SM; Rothman, N; Smith, MT; Vermeulen, R; Walker, DI; Yin, S; Zhang, L, 2021) |
"It is known that acquired chromosomal aberrations are positively correlated with cancer and reproductive risk." | 1.46 | Benzene poisoning, clinical and blood abnormalities in two Brazilian female gas station attendants: two case reports. ( Alves, G; Kosyakova, N; Liehr, T; Lima, S; Ornellas, MH; Otero, UB; Pinheiro, T; Santiago, F; Silvestre, RT; Tabalipa, MM, 2017) |
"The frequency of chromosome aberrations (CA) and micronuclei (MN) was investigated in the peripheral lymphocytes of workers occupationally exposed to low or very low concentrations of benzene." | 1.40 | Evaluation of chromosome aberration and micronucleus frequencies in blood lymphocytes of workers exposed to low concentrations of benzene. ( Bartolucci, GB; Carrieri, M; D'Errico, MN; Drago, I; Hrelia, P; Lovreglio, P; Maffei, F; Soleo, L, 2014) |
"Benzene is an industrial chemical that causes blood disorders, including acute myeloid leukemia." | 1.38 | Occupational exposure to benzene and chromosomal structural aberrations in the sperm of Chinese men. ( Eskenazi, B; Kurtovich, E; Li, G; Marchetti, F; Rappaport, SM; Schmid, TE; Weldon, RH; Wyrobek, AJ; Xing, C; Zhang, L, 2012) |
"Frequent karyotypic changes were trisomy 8 (9." | 1.38 | Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience. ( Alimena, G; Breccia, M; Finsinger, P; Latagliata, R; Loglisci, G; Nanni, M; Petrucci, L; Salaroli, A; Santopietro, M; Serrao, A; Volpicelli, P, 2012) |
"Benzene exposure was measured in 33 petrochemical industry operators (PIO), 28 service station attendants (SSA), 21 gasoline pump maintenance workers (GPMW) and 51 non-exposed controls by GC-FID analysis." | 1.36 | Low air levels of benzene: correlation between biomarkers of exposure and genotoxic effects. ( Ballini, A; Bartolucci, GB; Carrieri, M; Doria, D; Fracasso, ME; Lovreglio, P; Manno, M; Soleo, L; Tranfo, G, 2010) |
"Benzene is a relatively common environmental and occupational contaminant with carcinogenic and clastogenic properties." | 1.35 | FISH detection of chromosome 1 aberration in human interphase and metaphase lymphocytes after exposure to benzene. ( Dianovsky, J; Holeckova, B; Piesova, E; Sivikova, K, 2008) |
"Significant chromosomal aberrations were induced mainly by BQ, BT and HQ, with moderate response shown by CT and BZ and least by MA." | 1.35 | In silico studies with human DNA topoisomerase-II alpha to unravel the mechanism of in vitro genotoxicity of benzene and its metabolites. ( Ajmani, S; Bajpayee, M; Dhawan, A; Gurbani, D; Pandey, AK; Parmar, D, 2009) |
"Stable and unstable chromosome aberrations (CA) and sister chromatid exchanges (SCE) were examined." | 1.33 | Chromosome damage induced by benzene after the use of conventional and FISH chromosome painting. ( Dianovský, J; Holecková, B; Siviková, K, 2005) |
"The frequencies of total chromosome aberrations were significantly associated with benzene concentration after adjusting for confounding variables such as age, smoking status, and alcohol intake." | 1.32 | Determination of chromosome aberrations in workers in a petroleum refining factory. ( Cho, YH; Chung, HW; Kim, YJ; Paek, D, 2004) |
"In our investigation the occurrence of chromosome aberrations negatively correlated with CD25 (IL-2R) expression in both CD4 and CD8 positive T cells." | 1.31 | Lymphocyte phenotype analysis and chromosome aberration frequency of workers occupationally exposed to styrene, benzene, polycyclic aromatic hydrocarbons or mixed solvents. ( Biró, A; Falus, A; Jakab, MG; Klupp, T; Major, J; Pállinger, E; Tompa, A, 2002) |
"Elevated frequencies of chromosomal aberrations have been observed in the lymphocytes of benzene-exposed workers." | 1.31 | Characterization and mechanisms of chromosomal alterations induced by benzene in mice and humans. ( Chen, H; Eastmond, DA; Frantz, C; Hasegawa, L; Parks, R; Schuler, M; Wang, L, 2001) |
"To study the frequency of numerical chromosome aberrations in sperm of workers exposed to benzene series, the aneuploidy frequencies of 9 and 18 chromosomes were detected in sperm of workers by two color fluorescence in situ hybridization with digoxingenin labeled 9 chromosome probe (D9z1) and biotin labelled 18 chromosome probe (D18z1)." | 1.31 | [Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization]. ( Deng, LX; Li, X; Zhang, Q; Zheng, LK, 2001) |
"Benzene exposure was associated with significant increases in hyperdiploidy of chromosomes 8 (1." | 1.30 | Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene. ( Dosemeci, M; Hayes, RB; Kolachana, P; Li, G; Rothman, N; Smith, MT; Titenko-Holland, N; Wang, Y; Wiemels, J; Xi, L; Yin, S; Zhang, L, 1998) |
"Leukemia is the most common cancer in children." | 1.30 | Biomarkers of leukemia risk: benzene as a model. ( Smith, MT; Zhang, L, 1998) |
"The mitotic index (MI), chromosome aberrations (CAs), sister chromatid exchanges (SCEs) and satellite associations (SAs) were analysed." | 1.30 | Effect of polycyclic aromatic hydrocarbons on somatic chromosomes of coal tar workers. ( Seth, N; Yadav, JS, 1998) |
"The incidence of structural chromosome aberrations and sister chromatid exchanges was studied in the peripheral blood lymphocytes cell genome of 49 female shoe-makers, mean age 38 years, mean length of occupational exposure 17 years and in a group of 27 well-matched controls." | 1.30 | Genotoxic effects in workers exposed to benzene: with special reference to exposure biomarkers and confounding factors. ( Bogadi-Sare, A; Brumen, V; Karacić, V; Turk, R; Zavalić, M, 1997) |
"Benzene is a human carcinogen present naturally in petroleum and gasoline." | 1.30 | Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells. ( Barrett, JC; Hayashi, N; Huff, J; Maizumi, H; Tsutsui, T, 1997) |
"Benzene is a well-characterized human carcinogen and clastogen still present in both the occupational and general environment." | 1.30 | Molecular cytogenetic analysis of buccal cells and lymphocytes from benzene-exposed workers. ( Autio, K; Järventaus, H; Norppa, H; Nylund, L; Peltonen, K; Sorsa, M; Surrallés, J; Veidebaum, T, 1997) |
"Preliminary data of chromosome aberrations (CA) and sister chromatid exchanges (SCE) showed differences among sampling subgroups." | 1.29 | Biological monitoring of workers exposed to emissions from petroleum plants. ( Anderson, D; Cebulska-Wasilewska, A; Hughes, JA; Kasper, E; Wierzewska, A, 1996) |
"Five deaths were from neoplasia (acute erythroleukemia, brain tumor, cancer of lung, paranasal cavity, esophagus)." | 1.29 | Benzene-induced chromosome aberrations: a follow-up study. ( Forni, A, 1996) |
"The incidence of chromosomal aberrations (particularly chromatid gaps and breaks) in the exposed group was significantly higher than in the control group." | 1.29 | Analysis of chromosomal aberrations in shoe workers exposed long term to benzene. ( Egeli, U; Türkel, B, 1994) |
"Benzene content was determined to be between 0 and 28." | 1.29 | Cytogenetic findings on shoe workers exposed long-term to benzene. ( Egeli, U; Tunca, BT, 1996) |
"These data demonstrate that both aneuploidy and chromosomal breakage are early genotoxic events induced by benzene or its metabolites in vivo and also indicate that the nature of the chromosomal alterations may vary depending on the target organ or cell type." | 1.29 | Chromosomal loss and breakage in mouse bone marrow and spleen cells exposed to benzene in vivo. ( Chen, H; Eastmond, DA; Rupa, DS; Tomar, R, 1994) |
"Structural chromosome aberrations and sister chromatid exchanges (SCEs) in peripheral blood were studied in female workers employed in the shoe-making industry in two periods: 1987 (group I; N = 38) and 1992 (group II; N = 45)." | 1.29 | Possible genotoxicity in low level benzene exposure. ( Bogadi-Sare, A; Bosner-Cucancić, B; Karacić, V; Skender, L, 1995) |
"Praziquantel (PQ) is a commonly used drug to treat schistosomiasis patients." | 1.29 | Praziquantel (antischistosomal drug): is it clastogenic, co-clastogenic or anticlastogenic? ( Anwar, WA, 1994) |
"Chromosome aberrations were not associated with chemical exposures (OR = 1." | 1.29 | Myeloid leukemias and myelodysplastic syndromes: chemical exposure, histologic subtype and cytogenetics in a case-control study. ( Ciccone, G; Davico, L; Gavarotti, P; Levis, A; Mirabelli, D; Rege-Cambrin, G; Vineis, P, 1993) |
"Benzene is a recognized hematotoxin and leukemogen, but its mechanisms of action in humans are still uncertain." | 1.29 | An epidemiologic study of early biologic effects of benzene in Chinese workers. ( Bechtold, WE; Campleman, S; Dosemeci, M; Haas, R; Hayes, RB; Irons, RD; Kolachana, P; Li, GL; Linet, M; Lu, W; Meyer, KB; Quintana, PJ; Rothman, N; Smith, MT; Stillman, WS; Titenko-Holland, N; Wang, YZ; Wiemels, J; Xi, LQ; Yin, S; Zhang, L, 1996) |
"A significant increase in chromosome aberrations was observed." | 1.28 | Nonrandom distribution of breakpoints in the karyotypes of workers occupationally exposed to benzene. ( Sasiadek, M, 1992) |
" Based on prior studies, the lack of a dose-response indicator from internal plutonium was not unexpected because of the small sample and the low frequency of aberrations induced at the lower plutonium burdens." | 1.28 | Sister chromatid exchanges and chromosome aberration frequencies in plutonium workers. ( Bistline, RW; Bloom, AD; Brandom, WF; McGavran, L, 1990) |
"Significant increases in chromosome aberrations in spleen lymphocytes were observed in exposed compared with control mice except in the high-dose group (p less than 0." | 1.28 | Chromosome aberrations in lymphocytes of mice after sub-acute low-level inhalation exposure to benzene. ( Au, WW; Legator, MS; Ramanujam, VM; Ward, JB, 1991) |
"The aim of this work is to analyse chromosome aberrations and cell cycle kinetics in workers occupationally exposed to organic solvents, which contain benzene among other agents." | 1.28 | Genotoxic effects observed in workers occupationally exposed to organic solvents. ( Jagielski, J; Sasiadek, M, 1990) |
"Benzene is an established human leukemogen." | 1.28 | Characterization of micronuclei induced in human lymphocytes by benzene metabolites. ( Eastmond, DA; Paradisin, WM; Robertson, ML; Smith, MT; Yager, JW, 1990) |
"The incidence of chromosomal aberrations (particularly chromatid deletions and gaps) in the exposed group were slightly increased compared with the control group." | 1.28 | Analysis of chromosomal aberrations in workers exposed to low level benzene. ( Anderson, D; Jenkinson, PC; Lovell, DP; Yardley-Jones, A, 1990) |
"In the examined group structural chromosome aberrations were found in 147 metaphases (4." | 1.28 | Localization of breakpoints in the karyotype of workers professionally exposed to benzene. ( Jagielski, J; Sasiadek, M; Smolik, R, 1989) |
"The rate of cells with chromosome aberrations increased as the benzene level was raised (upon both administration routes) and was satisfactorily depicted by linear equations." | 1.27 | [Relation of the frequency of chromosome aberrations in mouse bone marrow cells to the concentration (dose) of benzene administered by various routes]. ( Fel'dt, EG; Kosiakov, VV; Zhurkov, VS, 1983) |
"Benzene has been known to be a bone marrow poison for almost a century." | 1.27 | Benzene: epidemiologic observations of leukemia by cell type and adverse health effects associated with low-level exposure. ( Infante, PF; White, MC, 1983) |
"The induction of chromosome aberrations in lymphocytes of mice after subchronic exposure to benzene was investigated." | 1.27 | Induction of chromosome aberrations in lymphocytes of mice after subchronic exposure to benzene. ( Au, WW; Legator, MS; Ramanujam, VM; Rithidech, K; Whorton, EB, 1987) |
"These endpoints include chromosomal aberrations in peripheral lymphocytes and sister chromatid exchanges." | 1.27 | Biomonitoring of exposure to potential mutagens and carcinogens in industrial populations. ( de Jong, G; van Sittert, NJ, 1985) |
"An approach to surveillance for chromosomal abnormalities in offspring of occupationally exposed parents is outlined." | 1.26 | Risks to the offspring from parental occupational exposures. ( Haas, JF; Schottenfeld, D, 1979) |
" 4) The experiment with dosage fractionation method showed that the more strongly benzene could inhibit the rejoining of radiation-induced chromosome breaks, the higher concentration it was treated at." | 1.26 | Analysis of combined effects of benzene with radiation on chromosomes in cultured human leukocytes. ( Morimoto, K, 1976) |
"Phenobarbital pretreatment synergistically interacted with benzene exposure to further increase sister chromatid exchanges in female mice, induce greater inhibition of cellular proliferation in male mice, and induce a significant level of chromatid-type chromosomal aberrations in both sexes." | 1.26 | Cytogenetic effects of inhaled benzene in murine bone marrow: induction of sister chromatid exchanges, chromosomal aberrations, and cellular proliferation inhibition in DBA/2 mice. ( Costa, DL; Drew, RT; Tice, RR, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 84 (49.12) | 18.7374 |
1990's | 38 (22.22) | 18.2507 |
2000's | 31 (18.13) | 29.6817 |
2010's | 15 (8.77) | 24.3611 |
2020's | 3 (1.75) | 2.80 |
Authors | Studies |
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Rothman, N | 5 |
Vermeulen, R | 1 |
Zhang, L | 8 |
Hu, W | 1 |
Yin, S | 4 |
Rappaport, SM | 2 |
Smith, MT | 9 |
Jones, DP | 1 |
Rahman, M | 1 |
Lan, Q | 1 |
Walker, DI | 1 |
Zhou, Y | 1 |
Wang, K | 1 |
Wang, B | 1 |
Pu, Y | 1 |
Zhang, J | 1 |
Tian, W | 1 |
Wang, TS | 1 |
Fang, Y | 1 |
Wu, HT | 1 |
Zheng, GQ | 1 |
Guo, KR | 1 |
Huang, M | 2 |
Sun, DY | 1 |
Xia, ZL | 1 |
Liang, BX | 1 |
Liu, XX | 3 |
Chen, LP | 1 |
Yang, AC | 1 |
Deng, QF | 1 |
Chen, W | 1 |
Xiao, YM | 1 |
Irons, RD | 3 |
Chen, Y | 1 |
Wang, X | 1 |
Ryder, J | 1 |
Kerzic, PJ | 1 |
Trevisan, P | 1 |
da Silva, JN | 1 |
da Silva, AP | 1 |
Rosa, RF | 1 |
Paskulin, GA | 1 |
Thiesen, FV | 1 |
de Oliveira, CA | 1 |
Zen, PR | 1 |
Mukhopadhyay, MK | 1 |
Nath, D | 1 |
Lovreglio, P | 2 |
Maffei, F | 1 |
Carrieri, M | 2 |
D'Errico, MN | 1 |
Drago, I | 1 |
Hrelia, P | 2 |
Bartolucci, GB | 2 |
Soleo, L | 2 |
Gonçalves, RO | 1 |
de Almeida Melo, N | 1 |
Rêgo, MA | 1 |
Lehman, CE | 1 |
Dillon, LW | 1 |
Nikiforov, YE | 1 |
Wang, YH | 1 |
Santiago, F | 1 |
Lima, S | 1 |
Pinheiro, T | 1 |
Silvestre, RT | 1 |
Otero, UB | 1 |
Tabalipa, MM | 1 |
Kosyakova, N | 1 |
Ornellas, MH | 1 |
Liehr, T | 1 |
Alves, G | 1 |
Holeckova, B | 3 |
Piesova, E | 2 |
Sivikova, K | 3 |
Dianovsky, J | 3 |
Pandey, AK | 1 |
Gurbani, D | 1 |
Bajpayee, M | 1 |
Parmar, D | 1 |
Ajmani, S | 1 |
Dhawan, A | 1 |
Nakayama, A | 1 |
Isono, T | 1 |
Kikuchi, T | 1 |
Ohnishi, I | 1 |
Igarashi, J | 1 |
Yoneda, M | 1 |
Morisawa, S | 1 |
Fracasso, ME | 1 |
Doria, D | 1 |
Ballini, A | 1 |
Tranfo, G | 1 |
Manno, M | 1 |
Xing, C | 2 |
Marchetti, F | 2 |
Li, G | 5 |
Weldon, RH | 2 |
Kurtovich, E | 2 |
Young, S | 1 |
Schmid, TE | 2 |
Rappaport, S | 1 |
Waidyanatha, S | 1 |
Wyrobek, AJ | 2 |
Eskenazi, B | 2 |
Regev, L | 1 |
Wu, M | 1 |
Zlotolow, R | 1 |
Brautbar, N | 1 |
Mazzeo, DE | 1 |
Fernandes, TC | 1 |
Marin-Morales, MA | 1 |
Breccia, M | 1 |
Finsinger, P | 1 |
Loglisci, G | 1 |
Santopietro, M | 1 |
Salaroli, A | 1 |
Serrao, A | 1 |
Latagliata, R | 1 |
Volpicelli, P | 1 |
Petrucci, L | 1 |
Nanni, M | 1 |
Alimena, G | 1 |
Hu, XX | 1 |
Chen, J | 1 |
Yang, YP | 1 |
Li, NN | 1 |
Yang, B | 1 |
Yang, R | 1 |
Li, XL | 1 |
Zheng, H | 1 |
TOUGH, IM | 2 |
BROWN, WM | 1 |
Stronati, L | 1 |
Farris, A | 1 |
Pacchierotti, F | 2 |
Tang, GH | 1 |
Yuan, YX | 1 |
Deng, LX | 3 |
Zhang, Q | 3 |
Zheng, LK | 3 |
Ji, Z | 1 |
Li, L | 2 |
Gao, Y | 1 |
Zhao, T | 1 |
He, Y | 1 |
Kim, YJ | 1 |
Cho, YH | 1 |
Paek, D | 1 |
Chung, HW | 1 |
Ji, ZY | 1 |
Li, GL | 2 |
Yin, SN | 1 |
Testa, A | 1 |
Festa, F | 1 |
Ranaldi, R | 2 |
Giachelia, M | 1 |
Tirindelli, D | 1 |
De Marco, A | 1 |
Owczarek, M | 1 |
Guidotti, M | 1 |
Cozzi, R | 1 |
Tompa, A | 5 |
Jakab, MG | 3 |
Major, J | 4 |
Albertini, RJ | 1 |
Sram, RJ | 1 |
Vacek, PM | 1 |
Lynch, J | 1 |
Rossner, P | 1 |
Nicklas, JA | 1 |
McDonald, JD | 1 |
Boysen, G | 1 |
Georgieva, N | 1 |
Swenberg, JA | 1 |
Natelson, EA | 1 |
Hatzi, VI | 1 |
Terzoudi, GI | 1 |
Pantelias, GE | 1 |
Spiliopoulou, C | 1 |
Makropoulos, V | 1 |
Guo, W | 1 |
Yang, W | 1 |
Hubbard, AE | 1 |
Hayes, RB | 3 |
Lu, W | 2 |
Endoh, K | 1 |
Murakami, M | 1 |
Sugiyama, T | 1 |
Taki, Y | 1 |
Umegaki, K | 1 |
Ahmad Khan, H | 1 |
Snyder, R | 2 |
Wen, T | 1 |
Meng, XL | 1 |
Zhang, H | 1 |
Wu, B | 1 |
You, T | 1 |
Wang, ZQ | 1 |
Melino, C | 1 |
Ding, XJ | 1 |
Li, Y | 1 |
Ding, Y | 1 |
Yang, HZ | 1 |
Sofuni, T | 1 |
Hayashi, M | 1 |
Matsuoka, A | 1 |
Sawada, M | 1 |
Hatanaka, M | 1 |
Ishidate, M | 1 |
Infante, PF | 2 |
White, MC | 2 |
Zhurkov, VS | 1 |
Fel'dt, EG | 2 |
Kosiakov, VV | 1 |
Styles, JA | 1 |
Richardson, CR | 2 |
Clare, MG | 1 |
Yardley-Jones, A | 2 |
Maclean, AC | 1 |
Dean, BJ | 2 |
van Raalte, HG | 1 |
Grasso, P | 1 |
Anderson, D | 3 |
Tice, RR | 2 |
Costa, DL | 1 |
Drew, RT | 1 |
Dabney, BJ | 1 |
Walker, B | 1 |
Zhong, BZ | 1 |
Meyne, J | 1 |
Legator, MS | 8 |
Siou, G | 1 |
Conan, L | 1 |
el Haitem, M | 1 |
Watanabe, T | 2 |
Endo, A | 1 |
Kato, Y | 1 |
Shima, S | 1 |
Ikeda, M | 1 |
Rank, J | 1 |
Nielsen, MH | 1 |
Anwar, WA | 1 |
Eastmond, DA | 8 |
Rupa, DS | 2 |
Hasegawa, LS | 1 |
Chen, H | 4 |
Armstrong, MJ | 1 |
Galloway, SM | 1 |
Karacić, V | 2 |
Skender, L | 1 |
Bosner-Cucancić, B | 1 |
Bogadi-Sare, A | 2 |
Nikiforov, B | 1 |
Davidkova, E | 1 |
Tomar, R | 1 |
Türkel, B | 1 |
Egeli, U | 2 |
Jakab, M | 1 |
Kiss, G | 1 |
Ciccone, G | 1 |
Mirabelli, D | 1 |
Levis, A | 1 |
Gavarotti, P | 1 |
Rege-Cambrin, G | 1 |
Davico, L | 1 |
Vineis, P | 1 |
Witz, G | 1 |
Goldstein, BD | 1 |
Morimoto, K | 2 |
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34 reviews available for benzene and Abnormalities, Autosome
Article | Year |
---|---|
Occupational benzene exposure and the risk of genetic damage: a systematic review and meta-analysis.
Topics: Adult; Benzene; Carcinogens; Case-Control Studies; Chromosome Aberrations; DNA Damage; Female; Human | 2020 |
Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature.
Topics: Adult; Animals; Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pai | 2012 |
Evaluation of chromosome painting to assess the induction and persistence of chromosome aberrations in bone marrow cells of mice treated with benzene.
Topics: Animals; Benzene; Bone Marrow Cells; Chromosome Aberrations; Chromosome Painting; Mice; Mutagens | 2004 |
Chromosomal aberrations in humans induced by benzene.
Topics: Benzene; Chromosome Aberrations; Cytogenetic Analysis; DNA Damage; Humans; In Situ Hybridization, Fl | 2004 |
[Risk of leukemia related with benzene and chromosomal aberrations.].
Topics: Benzene; Carcinogens; Chromosome Aberrations; Genetic Predisposition to Disease; Humans; Leukemia | 2005 |
[Theory and practice of primary cancer prevention].
Topics: Antioxidants; Apoptosis; Benzene; Biomarkers, Tumor; Carcinogens; Chemical Industry; Chromosome Aber | 2007 |
Benzene-induced acute myeloid leukemia: a clinician's perspective.
Topics: Acute Disease; Attitude of Health Personnel; Benzene; Chromosome Aberrations; Chromosome Inversion; | 2007 |
Benzene's toxicity: a consolidated short review of human and animal studies.
Topics: Animals; Benzene; Biotransformation; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; D | 2007 |
Hematological, myelotoxic, clastogenic, carcinogenic, and leukemogenic effects of benzene.
Topics: Animals; Benzene; Bone Diseases; Carcinogens; Chromosome Aberrations; Environmental Pollutants; Hodg | 1982 |
The role of human genetic monitoring in the workplace.
Topics: Benzene; Body Fluids; Chromosome Aberrations; Cytogenetics; Epichlorohydrin; Genetic Techniques; Hum | 1981 |
Occupational exposure to benzene: a review of carcinogenic and related health effects following the U.S. Supreme Court decision.
Topics: Animals; Benzene; Carcinogens; Chromosome Aberrations; Dose-Response Relationship, Drug; Epidemiolog | 1980 |
[The permissible concentrations of benzene in the atmospheric air of populated locations].
Topics: Air Pollutants; Benzene; Chromosome Aberrations; Drug Interactions; Humans; Leukemia; Maximum Allowa | 1994 |
The toxicology of benzene.
Topics: Animals; Benzene; Chromosome Aberrations; Hematopoiesis; Humans; Mutagens; Neoplasms | 1993 |
The process of leukemogenesis.
Topics: Benzene; Carcinogens; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 5; Cocar | 1996 |
Benzene-induced genotoxicity: a different perspective.
Topics: Animals; Benzene; Carcinogens; Chromosome Aberrations; DNA; Humans | 2000 |
Chromosome damage from biological reactive intermediates of benzene and 1,3-butadiene in leukemia.
Topics: Benzene; Butadienes; Carcinogens; Chromosome Aberrations; Humans; Leukemia; Lymphoma; Risk Assessmen | 2001 |
The nature of chromosomal aberrations detected in humans exposed to benzene.
Topics: Adult; Aged; Aged, 80 and over; Benzene; Biomarkers; Carcinogens; Chromosome Aberrations; Female; Hu | 2002 |
Cytologic and cytogenetic effects of benzene.
Topics: Animals; Benzene; Carcinogens; Cell Nucleus; Chromosome Aberrations; Humans; In Vitro Techniques; Mu | 1977 |
Benzene--attempts to establish a lower exposure standard in the United States. A review.
Topics: Air Pollutants; Air Pollutants, Occupational; Anemia, Aplastic; Benzene; Carcinogens; Chromosome Abe | 1978 |
[Significance and limitations of the study of chromosome aberrations in occupational medicine].
Topics: Benzene; Chromosome Aberrations; Humans; Lead Poisoning; Leukemia; Leukemia, Radiation-Induced; Merc | 1978 |
[Chromosome changes induced by industrial chemicals (author's transl)].
Topics: Adult; Animals; Benzene; Chromosome Aberrations; Cytogenetics; Environmental Exposure; Female; Human | 1979 |
Chromosome changes and benzene exposure. A review.
Topics: Adult; Benzene; Bone Marrow; Cell Cycle; Chromosome Aberrations; Chromosomes; Environmental Exposure | 1979 |
Genetic toxicology of benzene, toluene, xylenes and phenols.
Topics: Animals; Benzene; Biotransformation; Carcinogens; Catechols; Cats; Chickens; Chiroptera; Chromosome | 1978 |
Cytogenetic assays in genotoxic studies: somatic cell effects of benzene and germinal cell effects of dibromochloropropane.
Topics: Animals; Benzene; Chromosome Aberrations; Lymphocytes; Mutagenicity Tests; Mutagens; Propane | 1990 |
Genetic effects of benzene, toluene and xylene.
Topics: Animals; Benzene; Chromosome Aberrations; Humans; Mutagenicity Tests; Mutation; Toluene; Xylenes | 1988 |
[Short-term tests in the system of assessment of human carcinogens].
Topics: 2-Naphthylamine; Animals; Benzene; Carcinogens, Environmental; Cells, Cultured; Chromosome Aberratio | 1986 |
[Effect of benzene on the body in the light of genetic studies].
Topics: Air Pollutants, Occupational; Animals; Benzene; Chromosome Aberrations; DNA Replication; Humans; In | 1986 |
[Debatable questions of the leukemogenic (blastomogenic) action of benzine].
Topics: Animals; Benzene; Chromosome Aberrations; DNA; Dose-Response Relationship, Drug; Humans; Immune Tole | 1985 |
Environmental factors and leukaemia.
Topics: Acute Disease; Animals; Benzene; Cattle; Chromosome Aberrations; Electromagnetic Phenomena; Environm | 1985 |
Mutagenicity of selected organic solvents.
Topics: Animals; Benzene; Chromosome Aberrations; Ethanol; Genes; Humans; Mutagenicity Tests; Mutagens; Sist | 1985 |
Increased aromatics in motor fuels: a review of the environmental and health effects.
Topics: Air Pollution; Aldehydes; Animals; Benzene; Bone Marrow; Carcinogens; Central Nervous System; Chromo | 1974 |
Chromosome damage induced by chemicals.
Topics: Antineoplastic Agents; Aspirin; Benzene; Caffeine; Chloramphenicol; Chlorine; Chlorpromazine; Chromo | 1973 |
Clinical epidemiology of leukemia.
Topics: Adolescent; Age Factors; Anemia, Pernicious; Benzene; Child, Preschool; Chloramphenicol; Chromosome | 1969 |
Progress in the leukemias.
Topics: Alkylating Agents; Androgens; Anemia, Hemolytic, Autoimmune; Benzene; Blood Transfusion; Bone Marrow | 1971 |
137 other studies available for benzene and Abnormalities, Autosome
Article | Year |
---|---|
Metabolome-wide association study of occupational exposure to benzene.
Topics: Adult; Benzene; Biomarkers; China; Chromosome Aberrations; Cross-Sectional Studies; Female; Hematopo | 2021 |
Aberrant lncRNA Profiles Are Associated With Chronic Benzene Poisoning and Acute Myelocytic Leukemia.
Topics: Adult; Benzene; Chromosome Aberrations; Female; Gene Expression Regulation; Humans; Leukemia, Myeloi | 2020 |
[Value of DNA content in comet tail in predicting changes in blood cell counts in workers exposed to benzene].
Topics: Air Pollutants, Occupational; Benzene; Blood Cell Count; Chromosome Aberrations; Comet Assay; Humans | 2017 |
Acute myeloid leukemia following exposure to benzene more closely resembles de novo than therapy related-disease.
Topics: Benzene; China; Chromosome Aberrations; Cohort Studies; Environmental Exposure; Flow Cytometry; Huma | 2013 |
Evaluation of genotoxic effects of benzene and its derivatives in workers of gas stations.
Topics: Adult; Air Pollutants, Occupational; Benzene; Biomarkers; Chromosome Aberrations; Female; Gasoline; | 2014 |
Physiologically based toxicokinetic modeling of secondary acute myelolytic leukemia.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzene; Bone Marrow Cells; Carcinogens; | 2014 |
Evaluation of chromosome aberration and micronucleus frequencies in blood lymphocytes of workers exposed to low concentrations of benzene.
Topics: Acetylcysteine; Adult; Benzene; Biomarkers; Body Mass Index; Chromosome Aberrations; Environmental M | 2014 |
Association between occupational exposure to benzene and chromosomal alterations in lymphocytes of Brazilian petrochemical workers removed from exposure.
Topics: Adult; Aged; Benzene; Brazil; Chemical Industry; Chromosome Aberrations; DNA Damage; Environmental M | 2016 |
DNA fragile site breakage as a measure of chemical exposure and predictor of individual susceptibility to form oncogenic rearrangements.
Topics: Benzene; Carcinoma; Carcinoma, Papillary; Chromosome Aberrations; Chromosome Fragile Sites; Diethyln | 2017 |
Benzene poisoning, clinical and blood abnormalities in two Brazilian female gas station attendants: two case reports.
Topics: Abortion, Spontaneous; Adult; Benzene; Chromosome Aberrations; Chromosome Painting; Chromosomes; Fem | 2017 |
FISH detection of chromosome 1 aberration in human interphase and metaphase lymphocytes after exposure to benzene.
Topics: Adult; Benzene; Chromosome Aberrations; Chromosome Breakage; Chromosomes, Human, Pair 1; Dose-Respon | 2008 |
In silico studies with human DNA topoisomerase-II alpha to unravel the mechanism of in vitro genotoxicity of benzene and its metabolites.
Topics: Animals; Antigens, Neoplasm; Benzene; Benzene Derivatives; Catalytic Domain; CHO Cells; Chromosome A | 2009 |
Benzene risk estimation using radiation equivalent coefficients.
Topics: Adult; Benzene; Cells, Cultured; Chromosome Aberrations; Computer Simulation; Female; Humans; Inhala | 2009 |
Low air levels of benzene: correlation between biomarkers of exposure and genotoxic effects.
Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Benzene; Biomarkers; Chromosome Aberrations; Co | 2010 |
Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy.
Topics: Aneuploidy; Benzene; China; Chromosome Aberrations; Environmental Pollutants; Humans; In Situ Hybrid | 2010 |
Cellular damages in the Allium cepa test system, caused by BTEX mixture prior and after biodegradation process.
Topics: Bacteria; Benzene; Benzene Derivatives; Biodegradation, Environmental; Chromosome Aberrations; Mutag | 2011 |
Occupational exposure to benzene and chromosomal structural aberrations in the sperm of Chinese men.
Topics: Adult; Benzene; China; Chromosome Aberrations; Dose-Response Relationship, Drug; Environmental Pollu | 2012 |
Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience.
Topics: Acute Disease; Adult; Aged; Analysis of Variance; Benzene; Cell Transformation, Neoplastic; Chromoso | 2012 |
[Effects of benzene on S+G2/M cell cycle arrest, apoptosis and oxidative DNA damage in human peripheral blood mononuclear cells].
Topics: Apoptosis; Benzene; Chromosome Aberrations; DNA Damage; Dose-Response Relationship, Drug; G2 Phase C | 2012 |
CHROMOSOME ABERRATIONS AND EXPOSURE TO AMBIENT BENZENE.
Topics: Benzene; Chromosome Aberrations; Humans; Leukemia; Lymphocytes; Neoplasms; Occupational Diseases; Ra | 1965 |
[Detection of the frequencies of numerical and structural chromosome aberrations in sperm of benzene series-exposed workers by multi-color fluorescence in situ hybridization].
Topics: Adult; Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 18; Hum | 2003 |
[Chromosome aberration analysis of peripheral lymphocytes in workers exposed to benzene].
Topics: Adult; Benzene; Centromere; Chromosome Aberrations; Dose-Response Relationship, Drug; Female; Humans | 2004 |
[Detection of numerical aberrations of chromosomes 7 and 8 in sperms of workers exposed to benzene series by two-color fluorescence in situ hybridization].
Topics: Adult; Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Fema | 2004 |
Determination of chromosome aberrations in workers in a petroleum refining factory.
Topics: Adult; Benzene; Case-Control Studies; Chromosome Aberrations; Humans; Industry; Leukocyte Count; Mal | 2004 |
Chromosome damage induced by benzene after the use of conventional and FISH chromosome painting.
Topics: Animals; Benzene; Cattle; Cell Culture Techniques; Chromosome Aberrations; Chromosome Painting; DNA | 2005 |
A multi-biomarker analysis of DNA damage in automobile painters.
Topics: Adult; Automobiles; Benzene; Biomarkers; Case-Control Studies; Chromosome Aberrations; Chromosomes; | 2005 |
Risk management among benzene-exposed oil refinery workers.
Topics: Adult; Benzene; Biomarkers; Case-Control Studies; Cell Proliferation; Chromosome Aberrations; Chroni | 2005 |
Molecular epidemiological studies in 1,3-butadiene exposed Czech workers: female-male comparisons.
Topics: Acetylcysteine; Adult; Benzene; Butadienes; Chemical Industry; Chromosome Aberrations; Czech Republi | 2007 |
The benzene metabolite hydroquinone enhances G2-chromosomal radiosensitivity by inducing a less-efficient G2-M-checkpoint in irradiated lymphocytes.
Topics: Benzene; Carcinogens; Cell Division; Cells, Cultured; Chromosome Aberrations; G2 Phase; Humans; Hydr | 2007 |
Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers.
Topics: Adult; Benzene; Case-Control Studies; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Huma | 2007 |
Low folate status enhanced benzene-induced cytogenetic damage in bone marrow of mice: a relationship between dietary intake and tissue levels of folate.
Topics: Administration, Oral; Animals; Benzene; Bone Marrow Cells; Chromosome Aberrations; DNA Damage; Dose- | 2007 |
Benzene's toxicity: a consolidated short review of human and animal studies by HA Khan.
Topics: Animals; Benzene; Biotransformation; Bone Marrow; Cell Transformation, Neoplastic; Chromosome Aberra | 2007 |
[Genetic damages in somatic and germ cells from patients of benzene poisoning, asbestosis and gas poisoning.].
Topics: Asbestosis; Benzene; Chromosome Aberrations; Gas Poisoning; Humans; Occupational Diseases; Occupatio | 2007 |
[Changes of lymphocytic micronucleus rate and amount of hemoglobin F in the peripheral blood of workers with long-term exposure to benzene (author's transl)].
Topics: Adolescent; Adult; Benzene; Cell Nucleus; Chromosome Aberrations; Environmental Exposure; Female; Fe | 1981 |
[Benzene carcinogenesis].
Topics: Anemia, Aplastic; Benzene; Chromosome Aberrations; Humans; Leukopenia; Mitosis; Neoplasms; Thrombocy | 1984 |
Chromosome changes in patients with chronic benzene poisoning.
Topics: Benzene; Chromosome Aberrations; Chronic Disease; DNA; Female; Humans; Male | 1983 |
[Cytogenetic effects of gaseous and volatile chemicals on mammalian cells in vitro and in vivo. I. Chromosome aberration tests in cultured mammalian cells].
Topics: Acrylates; Animals; Benzene; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Ethyle | 1984 |
Benzene: epidemiologic observations of leukemia by cell type and adverse health effects associated with low-level exposure.
Topics: Adult; Aged; Benzene; Chromosome Aberrations; Dose-Response Relationship, Drug; Humans; Legislation | 1983 |
[Relation of the frequency of chromosome aberrations in mouse bone marrow cells to the concentration (dose) of benzene administered by various routes].
Topics: Animals; Benzene; Bone Marrow; Chromosome Aberrations; Dose-Response Relationship, Drug; Injections; | 1983 |
Cytogenetic effects of benzene: dosimetric studies on rats exposed to benzene vapour.
Topics: Animals; Benzene; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Dose-Response Relations | 1984 |
Chromosome analysis from peripheral blood lymphocytes of workers after an acute exposure to benzene.
Topics: Accidents, Occupational; Benzene; Chromosome Aberrations; Crossing Over, Genetic; Environmental Expo | 1984 |
Issues relevant to the assessment of chemically induced chromosome damage in vivo and their relationship to chemical mutagenesis.
Topics: Animals; Benzene; Bone Marrow; Chromosome Aberrations; Chromosomes; Ethyl Methanesulfonate; Male; Mi | 1981 |
Cytogenetic effects of inhaled benzene in murine bone marrow: induction of sister chromatid exchanges, chromosomal aberrations, and cellular proliferation inhibition in DBA/2 mice.
Topics: Animals; Benzene; Biotransformation; Bone Marrow; Bromodeoxyuridine; Cell Division; Chromosome Aberr | 1980 |
[An experimental study on chromosome aberration induced by benzene (author's transl)].
Topics: Animals; Benzene; Chromosome Aberrations; Female; Rats | 1980 |
Sex-related differences in cytogenetic effects of benzene in the bone marrow of Swiss mice.
Topics: Animals; Benzene; Bone Marrow; Cell Nucleus; Chromosome Aberrations; Erythrocytes; Female; Male; Met | 1980 |
Evaluation of the clastogenic action of benzene by oral administration with 2 cytogenetic techniques in mouse and Chinese hamster.
Topics: Administration, Oral; Animals; Benzene; Bone Marrow; Chromosome Aberrations; Chromosomes; Cricetinae | 1981 |
Cytogenetics and cytokinetics of cultured lymphocytes from benzene-exposed workers.
Topics: Adult; Benzene; Chromosome Aberrations; Chromosome Disorders; Crossing Over, Genetic; Cytogenetics; | 1980 |
Monitoring of benzene-exposed workers for genotoxic effects of benzene: improved-working-condition-related decrease in the frequencies of chromosomal aberrations in peripheral blood lymphocytes.
Topics: Air Pollutants, Occupational; Benzene; Chemical Industry; Chromosome Aberrations; DNA; DNA Repair; D | 1994 |
Evaluation of the Allium anaphase-telophase test in relation to genotoxicity screening of industrial wastewater.
Topics: Allium; Benzene; Chromates; Chromosome Aberrations; Formaldehyde; Genes, Plant; Industrial Waste; Me | 1994 |
Praziquantel (antischistosomal drug): is it clastogenic, co-clastogenic or anticlastogenic?
Topics: Animals; Antimutagenic Agents; Benzene; Chromosome Aberrations; Egypt; Environmental Exposure; Epith | 1994 |
Detection of hyperdiploidy and chromosome breakage in interphase human lymphocytes following exposure to the benzene metabolite hydroquinone using multicolor fluorescence in situ hybridization with DNA probes.
Topics: Benzene; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human, Pair 9; Diploidy; DNA Probes; | 1994 |
Synergistic increase in chromosomal breakage within the euchromatin induced by an interaction of the benzene metabolites phenol and hydroquinone in mice.
Topics: Animals; Benzene; Chromatin; Chromosome Aberrations; DNA Repair; Drug Synergism; Hydroquinones; Male | 1995 |
Micronuclei induced in peripheral blood of E mu-PIM-1 transgenic mice by chronic oral treatment with 2-acetylaminofluorene or benzene but not with diethyl-nitrosamine or 1,2-dichloroethane.
Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Benzene; Chromosome Aberrations; Diethylnitros | 1993 |
Possible genotoxicity in low level benzene exposure.
Topics: Absorption; Adult; Air Pollutants, Occupational; Benzene; Biomarkers; Chromosome Aberrations; Chromo | 1995 |
Chromosomal loss and breakage in mouse bone marrow and spleen cells exposed to benzene in vivo.
Topics: Aneuploidy; Animals; Antibodies; Base Sequence; Benzene; Bone Marrow Cells; Chromosome Aberrations; | 1994 |
Analysis of chromosomal aberrations in shoe workers exposed long term to benzene.
Topics: Adult; Aged; Alcohol Drinking; Benzene; Chromosome Aberrations; Chromosome Disorders; Female; Humans | 1994 |
Chromosome aberration, sister-chromatid exchange, proliferative rate index, and serum thiocyanate concentration in smokers exposed to low-dose benzene.
Topics: Adult; Analysis of Variance; Benzene; Cell Division; Cells, Cultured; Chromosome Aberrations; Confou | 1994 |
Myeloid leukemias and myelodysplastic syndromes: chemical exposure, histologic subtype and cytogenetics in a case-control study.
Topics: Adolescent; Adult; Aged; Benzene; Case-Control Studies; Chromosome Aberrations; Electromagnetic Fiel | 1993 |
Chromosome alterations in peripheral lymphocytes as indices of lifestyle and genotoxicity.
Topics: Benzene; Biotransformation; Cells, Cultured; Chromosome Aberrations; Health Behavior; Humans; Life S | 1993 |
Biological monitoring of workers exposed to emissions from petroleum plants.
Topics: Adult; Air Pollutants, Occupational; Benzene; Chemical Industry; Chromosome Aberrations; Environment | 1996 |
Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells.
Topics: Aneuploidy; Animals; Benzene; Carcinogens; Catechols; Cells, Cultured; Chromosome Aberrations; Crice | 1997 |
Molecular cytogenetic analysis of buccal cells and lymphocytes from benzene-exposed workers.
Topics: Benzene; Cheek; Chromosome Aberrations; Chromosomes, Human, Pair 9; Humans; Lymphocytes; Micronucleu | 1997 |
Benzene-induced chromosome aberrations: a follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Benzene; Bone Marrow; Case-Control Studies; Chromosome Aberrations; | 1996 |
Cytogenetic findings on shoe workers exposed long-term to benzene.
Topics: Adult; Aged; Benzene; Case-Control Studies; Chromosome Aberrations; Cytogenetics; Female; Humans; Ly | 1996 |
Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites.
Topics: Animals; Benzene; Carcinogens; Chromosome Aberrations; Enzyme Inhibitors; Humans; In Vitro Technique | 1996 |
An epidemiologic study of early biologic effects of benzene in Chinese workers.
Topics: Adult; Benzene; Blood Cell Count; China; Chromosome Aberrations; Cross-Sectional Studies; Cytokines; | 1996 |
Genotoxic effects in workers exposed to benzene: with special reference to exposure biomarkers and confounding factors.
Topics: Adult; Air Pollutants, Occupational; Benzene; Case-Control Studies; Chromosome Aberrations; Confound | 1997 |
Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene.
Topics: Acute Disease; Adult; Benzene; Carcinogens; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chr | 1998 |
Biomarkers of leukemia risk: benzene as a model.
Topics: Adult; Benzene; Biomarkers; Child; Chromosome Aberrations; Environmental Exposure; Genetic Predispos | 1998 |
Effect of polycyclic aromatic hydrocarbons on somatic chromosomes of coal tar workers.
Topics: Air Pollutants, Occupational; Benzene; Benzo(a)pyrene; Carcinogens, Environmental; Cells, Cultured; | 1998 |
Measurement and characterization of micronuclei in cultured primary lung cells of mice following inhalation exposure to benzene.
Topics: Administration, Inhalation; Aneuploidy; Animals; Benzene; Cells, Cultured; Chromosome Aberrations; D | 1998 |
Cytogenetic changes in subjects occupationally exposed to benzene.
Topics: Adult; Benzene; Chromosome Aberrations; Female; Humans; Middle Aged; Occupational Exposure; Sister C | 2000 |
Biomarkers in the molecular epidemiology of benzene-exposed workers.
Topics: Acute Disease; Air Pollutants, Occupational; Benzene; Biomarkers; Chromosome Aberrations; Cyclohexan | 2000 |
[Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization].
Topics: Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 9; Humans; In | 2001 |
Characterization and mechanisms of chromosomal alterations induced by benzene in mice and humans.
Topics: Adult; Animals; Benzene; Carcinogens; Chromosome Aberrations; DNA Damage; DNA Topoisomerases, Type I | 2001 |
Lymphocyte phenotype analysis and chromosome aberration frequency of workers occupationally exposed to styrene, benzene, polycyclic aromatic hydrocarbons or mixed solvents.
Topics: Adult; Antigens, CD; Benzene; Chromosome Aberrations; Female; Gene Frequency; Humans; Immunophenotyp | 2002 |
[Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization].
Topics: Adult; Air Pollutants, Occupational; Aneuploidy; Benzene; Chromosome Aberrations; Female; Humans; In | 2000 |
Chromosome analysis in two unusual malignant blood disorders presumably induced by benzene.
Topics: Adult; Aged; Benzene; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Hemat | 1979 |
Risks to the offspring from parental occupational exposures.
Topics: Alcohol Drinking; Anesthetics; Benzene; Carcinogens; Chloroprene; Chromosome Aberrations; Chromosome | 1979 |
Cytogenetic study of workers exposed to benzene.
Topics: Adult; Age Factors; Benzene; Chromosome Aberrations; Environmental Exposure; Epidemiologic Methods; | 1979 |
International workshop on toxicology of benzene, Paris: 9th - 11th November 1976.
Topics: Animals; Benzene; Bone Marrow Diseases; Chromosome Aberrations; Environmental Exposure; Humans; Leuk | 1978 |
Combination of genetic factors and chronic exposure to benzene in the aetiology of leukaemia.
Topics: Acute Disease; Adult; Aged; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Leukemi | 1976 |
Analysis of combined effects of benzene with radiation on chromosomes in cultured human leukocytes.
Topics: Benzene; Cells, Cultured; Chromatids; Chromosome Aberrations; Chromosomes; Gamma Rays; Humans; Leuko | 1976 |
Acute cytogenetic effect of benzene on rat bone marrow cells in vivo and the effect of inducers or inhibitors of drug-metabolizing enzymes.
Topics: Animals; Azo Compounds; Benzene; Benzoquinones; Bone Marrow; Bone Marrow Cells; Chi-Square Distribut | 1992 |
Nonrandom distribution of breakpoints in the karyotypes of workers occupationally exposed to benzene.
Topics: Benzene; Chromosome Aberrations; Chromosome Disorders; Humans; Karyotyping; Lymphocytes; Occupationa | 1992 |
Cytogenetic effects in rotogravure printers exposed to toluene (and benzene).
Topics: Adult; B-Lymphocytes; Benzene; Chromosome Aberrations; Humans; Lymphocyte Activation; Male; Micronuc | 1991 |
Dose-related clastogenic effects induced by benzene in bone marrow cells and in differentiating spermatogonia of Swiss CD1 mice.
Topics: Administration, Oral; Animals; Benzene; Bone Marrow; Carcinogenicity Tests; Chromosome Aberrations; | 1991 |
Sister chromatid exchanges and chromosome aberration frequencies in plutonium workers.
Topics: Adult; Benzene; Beryllium; Carbon Tetrachloride; Chromosome Aberrations; Environmental Exposure; Hum | 1990 |
Benzene in petrol.
Topics: Benzene; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair | 1990 |
Chromosome aberrations in lymphocytes of mice after sub-acute low-level inhalation exposure to benzene.
Topics: Administration, Inhalation; Animals; Benzene; Chromosome Aberrations; Female; Lymphocytes; Male; Mic | 1991 |
Genotoxic effects observed in workers occupationally exposed to organic solvents.
Topics: Adult; Benzene; Chromosome Aberrations; Female; Humans; Male; Middle Aged; Occupational Exposure; So | 1990 |
Characterization of micronuclei induced in human lymphocytes by benzene metabolites.
Topics: Adult; Benzene; Benzoquinones; Catechols; Cells, Cultured; Chromosome Aberrations; Dose-Response Rel | 1990 |
Analysis of chromosomal aberrations in workers exposed to low level benzene.
Topics: Benzene; Chemical Industry; Chromosome Aberrations; Environmental Exposure; Humans; Male; Metaphase | 1990 |
[The experimental research of acupuncture and moxibustion in preventing mice benzene poisoning].
Topics: Acupuncture Therapy; Animals; Benzene; Chromosome Aberrations; Female; Leukocyte Count; Mice; Moxibu | 1989 |
Localization of breakpoints in the karyotype of workers professionally exposed to benzene.
Topics: Adult; Benzene; Chromosome Aberrations; Environmental Exposure; Female; Humans; Karyotyping; Lymphoc | 1989 |
Genetic effects of benzene and radiation in ICR and X/Gf mice.
Topics: Animals; Benzene; Benzo(a)pyrene; Chromosome Aberrations; Cyclophosphamide; Female; Male; Mice; Mice | 1989 |
The cytogenetic evaluation of in vivo genotoxic and cytotoxic activity using rodent somatic cells.
Topics: Animals; Benzene; Butadienes; Carcinogenicity Tests; Chloroprene; Chromosome Aberrations; Cyanates; | 1988 |
Genotoxic effects of a sub-acute low-level inhalation exposure to a mixture of carcinogenic chemicals.
Topics: Administration, Inhalation; Aerosols; Animals; Benzene; Body Weight; Carcinogens; Cell Nucleus; Chlo | 1988 |
Benzene and its biologic effects in humans. Discussion paper.
Topics: Benzene; Chromosome Aberrations; DNA; Humans | 1988 |
Exposure to benzene at different work places in Sweden.
Topics: Air Pollutants, Occupational; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Occup | 1987 |
The cytogenetic effects of benzene and toluene on bone marrow cells in rats.
Topics: Animals; Benzene; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Injections, Intraperito | 1987 |
Induction of chromosome aberrations in lymphocytes of mice after subchronic exposure to benzene.
Topics: Animals; Benzene; Chromosome Aberrations; Dose-Response Relationship, Drug; Lymphocytes; Male; Mice; | 1987 |
Cytogenetic analysis of peripheral blood lymphocytes in workers exposed to benzene.
Topics: Air Pollutants, Occupational; Benzene; Chromosome Aberrations; Czechoslovakia; Female; Humans; Karyo | 1987 |
Correlation between the induction of micronuclei in bone marrow by benzene exposure and the excretion of metabolites in urine of CD-1 mice.
Topics: Animals; Benzene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Bone Marrow; Catechols; Cel | 1986 |
[Immunologic and clastogenic changes in benzene-exposed workers].
Topics: Adult; Benzene; Chromosome Aberrations; Female; Humans; Immunologic Deficiency Syndromes; Male; Neop | 1986 |
Induction of cytogenetic damage in rodents after short-term inhalation of benzene.
Topics: Air Pollutants; Animals; Benzene; Bone Marrow; Cell Nucleus; Chromosome Aberrations; Dose-Response R | 1986 |
Low level benzene exposure in Sweden: effect on blood elements and body burden of benzene.
Topics: Air Pollutants, Occupational; Benzene; Body Burden; Chromosome Aberrations; Gasoline; Humans; Kineti | 1985 |
Benzene myeloclastogenicity: a function of its metabolism.
Topics: Animals; Benzene; Benzoflavones; beta-Naphthoflavone; Bone Marrow; Catechols; Chromosome Aberrations | 1985 |
Biomonitoring of exposure to potential mutagens and carcinogens in industrial populations.
Topics: Benzene; Carcinogens, Environmental; Chromosome Aberrations; DNA; Environmental Exposure; Epichloroh | 1985 |
[Assessment of the mutagenic hazards of benzene and its derivatives].
Topics: Animals; Benzene; Benzene Derivatives; Chromosome Aberrations; Dose-Response Relationship, Drug; Fem | 1985 |
Cancer risk and viral transformation.
Topics: Benzene; Carcinogens; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; | 1969 |
Persons with exceptionally high risk of leukemia.
Topics: Adult; Aneuploidy; Benzene; Child; Child, Preschool; Chromosome Aberrations; Diseases in Twins; Down | 1967 |
Chromosome aberrations--red herring or red flag?
Topics: Alkylating Agents; Anemia, Aplastic; Ataxia Telangiectasia; Benzene; Chromosome Aberrations; Down Sy | 1973 |
[Leukosis induced by benzene (author's transl)].
Topics: Anemia, Aplastic; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Leukemia; Occupat | 1974 |
Cytogenetic studies in thirteen patients with pancytopenia and leukaemia associated with long-term exposure to benzene.
Topics: Adult; Anemia, Aplastic; Benzene; Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Human, 6-1 | 1973 |
Acute leukaemia in two generations following chronic exposure to benzene.
Topics: Adult; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Leukemia, Lymphoid; Leukemia | 1974 |
[Transformation into acute leukemia of a case of involutive myelopathy due to benzene poisoning].
Topics: Anemia, Aplastic; Benzene; Chromosome Aberrations; Humans; Karyotyping; Leukemia, Myeloid, Acute; Ma | 1972 |
[Genetic activity of benzene and toluene].
Topics: Animals; Benzene; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Inje | 1973 |
[Cytogenetic studies following chronic exposure to benzene (author's transl)].
Topics: Adult; Benzene; Blood Cells; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Chromosome Abe | 1973 |
Preleukemic states.
Topics: Abnormalities, Multiple; Adolescent; Adult; Aged; Agranulocytosis; Anemia, Aplastic; Ataxia Telangie | 1974 |
Pathology of erythroblastic mitosis in occupational benzenic erythropathy and erythrema. In vivo and in vitro studies.
Topics: Animals; Benzene; Bone Marrow Examination; Cell Division; Cell Membrane; Cell Nucleus; Chromosome Ab | 1970 |
[Karyotype in preleukemic and preneoplastic conditions].
Topics: Anemia; Antineoplastic Agents; Benzene; Chloramphenicol; Chromosome Aberrations; Humans; Karyotyping | 1970 |
[Chromosome studies after chronic benzol exposure].
Topics: Acute Disease; Adult; Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Karyotyping; | 1972 |
Further studies on experimental benzene induced aplastic anemia.
Topics: Anemia, Aplastic; Animals; Autoradiography; Benzene; Bone Marrow; Bone Marrow Cells; Bone Marrow Exa | 1972 |
Chromosome studies in workers exposed to benzene or toluene or both.
Topics: Adult; Benzene; Blood Cell Count; Chemical Industry; Chromosome Aberrations; Humans | 1971 |
Chromosome changes and their evolution in subjects with past exposure to benzene.
Topics: Adult; Aneuploidy; Benzene; Blood Cell Count; Bone Marrow Cells; Cell Division; Chromosome Aberratio | 1971 |
Chromosome aberrations in experimental benzene intoxication.
Topics: Animals; Benzene; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Cytogene | 1971 |
[Aberrations of chromosome number and structure in industrial workers exposed to benzene].
Topics: Benzene; Chromosome Aberrations; Humans; Karyotyping; Male; Occupational Medicine | 1971 |
Chromosome studies in workers exposed to benzene or toluene or both.
Topics: Adult; Benzene; Blood Cell Count; Chemical Industry; Chromosome Aberrations; Hematologic Diseases; H | 1971 |
[Chromosome aberration in a benzol leukemia].
Topics: Benzene; Chromosome Aberrations; Environmental Exposure; Humans; Karyotyping; Leukemia, Myeloid, Acu | 1969 |
Chromosome anomalies in a case of benzene leukaemia.
Topics: Benzene; Chromosome Aberrations; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; M | 1969 |
Chromosome studies in a case of benzene-induced erythroleukaemia.
Topics: Adult; Benzene; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Female | 1969 |
Chromosome study in a case of granulocytic leukaemia with 'Pelgerisation' 7 years after benzene pancytopenia.
Topics: Adult; Anemia, Aplastic; Benzene; Chromosome Aberrations; Chromosomes; Humans; Karyotyping; Leukemia | 1971 |
[Chromosome changes of the lumphocytes discovered after five years in subjects with benzolic hemopathy].
Topics: Adult; Benzene; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1-3; Chromosomes, | 1969 |
Chromosome studies on workers exposed to atmospheric benzene. The possible influence of age.
Topics: Adolescent; Adult; Age Factors; Aged; Benzene; Chemical Industry; Chromosome Aberrations; Humans; Le | 1970 |
Benzene induced chromosome abnormalities in rat bone marrow cells.
Topics: Animals; Benzene; Bone Marrow Cells; Chromosome Aberrations; Male; Rats | 1970 |
[Benzene leukemia].
Topics: Benzene; Blood Sedimentation; Chromosome Aberrations; Disability Evaluation; Environmental Exposure; | 1969 |