Page last updated: 2024-10-23

benzbromarone and Pulmonary Arterial Hypertension

benzbromarone has been researched along with Pulmonary Arterial Hypertension in 2 studies

Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.

Pulmonary Arterial Hypertension: A progressive rare pulmonary disease characterized by high blood pressure in the PULMONARY ARTERY.

Research Excerpts

ExcerptRelevanceReference
"Vascular remodeling is promoted by the survival and proliferation of pulmonary arterial vascular cells in a DNA-damaging, hostile microenvironment."1.51The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension. ( Hegde, RS; Hu, YC; Mallela, J; Molkentin, JD; Nichols, WC; Pandey, RN; Wang, Y; Wikenheiser-Brokamp, KA; York, AJ, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Gao, J1
Yin, H1
Dong, Y1
Wang, X1
Liu, Y1
Wang, K1
Wang, Y1
Pandey, RN1
York, AJ1
Mallela, J1
Nichols, WC1
Hu, YC1
Molkentin, JD1
Wikenheiser-Brokamp, KA1
Hegde, RS1

Other Studies

2 other studies available for benzbromarone and Pulmonary Arterial Hypertension

ArticleYear
A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction.
    Molecular pharmacology, 2023, Volume: 103, Issue:4

    Topics: Asthma; Benzbromarone; Channelopathies; Humans; Large-Conductance Calcium-Activated Potassium Channe

2023
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
    Nature communications, 2019, 09-12, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Benzbromarone; Cardiomegaly; Cell Proliferation; Cell Survival; DNA Damage; DNA

2019