Page last updated: 2024-10-23

benzbromarone and Pseudoxanthoma Elasticum

benzbromarone has been researched along with Pseudoxanthoma Elasticum in 2 studies

Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.

Pseudoxanthoma Elasticum: An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iliás, A1
Urbán, Z1
Seidl, TL1
Le Saux, O1
Sinkó, E1
Boyd, CD1
Sarkadi, B1
Váradi, A1
Boraldi, F1
Quaglino, D1
Croce, MA1
Garcia Fernandez, MI1
Tiozzo, R1
Gheduzzi, D1
Bacchelli, B1
Pasquali Ronchetti, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)[NCT04660461]Phase 420 participants (Anticipated)Interventional2020-02-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for benzbromarone and Pseudoxanthoma Elasticum

ArticleYear
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).
    The Journal of biological chemistry, 2002, May-10, Volume: 277, Issue:19

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport; Blotting, Western;

2002
Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients.
    Matrix biology : journal of the International Society for Matrix Biology, 2003, Volume: 22, Issue:6

    Topics: Adult; Benzbromarone; Cell Count; Cell Division; Chlorambucil; Female; Fibroblasts; Fluoresceins; Fl

2003