benzbromarone and Necrosis studies

benzbromarone and Necrosis

benzbromarone has been researched along with Necrosis in 2 studies

Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

Excerpt	Relevance	Reference
"Benzbromarone is an uricosuric structurally related to amiodarone and a known mitochondrial toxicant."	1.40	Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. ( Felser, A; Jenö, P; Krähenbühl, S; Kratschmar, DV; Lindinger, PW; Mies, S; Odermatt, A; Schnell, D, 2014)
"Treatment with benzarone or benzbromarone can be associated with hepatic injury."	1.33	Mechanisms of benzarone and benzbromarone-induced hepatic toxicity. ( Gasser, R; Hänni, A; Kaufmann, P; Krähenbühl, S; Roberts, P; Török, M, 2005)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (50.00)

29.6817

2010's

1 (50.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Felser, A	1
Lindinger, PW	1
Schnell, D	1
Kratschmar, DV	1
Odermatt, A	1
Mies, S	1
Jenö, P	1
Krähenbühl, S	2
Kaufmann, P	1
Török, M	1
Hänni, A	1
Roberts, P	1
Gasser, R	1

Studies

Felser, A

Lindinger, PW

Schnell, D

Kratschmar, DV

Odermatt, A

Mies, S

Jenö, P

Krähenbühl, S

Kaufmann, P

Török, M

Hänni, A

Roberts, P

Gasser, R

Other Studies

2 other studies available for benzbromarone and Necrosis

Article	Year
Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology, 2014, Oct-03, Volume: 324 Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzbromarone; Chemical and Drug Induced Liver Injury; D	2014
Mechanisms of benzarone and benzbromarone-induced hepatic toxicity. Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:4 Topics: Amiodarone; Animals; Apoptosis; Benzbromarone; Benzofurans; Cell Line, Tumor; Hepatocytes; Ketone Bo	2005

Article

Year

Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure.

Toxicology, 2014, Oct-03, Volume: 324

Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzbromarone; Chemical and Drug Induced Liver Injury; D

2014

Mechanisms of benzarone and benzbromarone-induced hepatic toxicity.

Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:4

Topics: Amiodarone; Animals; Apoptosis; Benzbromarone; Benzofurans; Cell Line, Tumor; Hepatocytes; Ketone Bo

2005