benzbromarone has been researched along with Liver Cirrhosis in 2 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The disposition of benzbromarone and its uric acid lowering effect were investigated in 8 patients with compensated liver cirrhosis in order to obtain evidence whether dose requirements differ from subjects with normal liver function." | 7.69 | Biotransformation and uric acid lowering effect of benzbromarone in patients with liver cirrhosis - evidence for active benzbromarone metabolites? ( de Vries, JX; Pfleilschifter, V; Raedsch, R; von Bubnoff, A; Walter-Sack, I, 1995) |
| "The disposition of benzbromarone and its uric acid lowering effect were investigated in 8 patients with compensated liver cirrhosis in order to obtain evidence whether dose requirements differ from subjects with normal liver function." | 3.69 | Biotransformation and uric acid lowering effect of benzbromarone in patients with liver cirrhosis - evidence for active benzbromarone metabolites? ( de Vries, JX; Pfleilschifter, V; Raedsch, R; von Bubnoff, A; Walter-Sack, I, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hautekeete, ML | 1 |
| Henrion, J | 1 |
| Naegels, S | 1 |
| DeNeve, A | 1 |
| Adler, M | 1 |
| Deprez, C | 1 |
| Devis, G | 1 |
| Klöppel, G | 1 |
| Walter-Sack, I | 1 |
| de Vries, JX | 1 |
| von Bubnoff, A | 1 |
| Pfleilschifter, V | 1 |
| Raedsch, R | 1 |
2 other studies available for benzbromarone and Liver Cirrhosis
| Article | Year |
|---|---|
Severe hepatotoxicity related to benzarone: a report of three cases with two fatalities.
Topics: Adult; Aged; Benzbromarone; Biopsy; Chemical and Drug Induced Liver Injury; Chemical and Drug Induce | 1995 |
Biotransformation and uric acid lowering effect of benzbromarone in patients with liver cirrhosis - evidence for active benzbromarone metabolites?
Topics: Adult; Benzbromarone; Female; Humans; Liver Cirrhosis; Middle Aged; Uric Acid; Uricosuric Agents | 1995 |