benzbromarone has been researched along with Kidney Failure, Chronic in 9 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have retrospectively evaluated the uric acid control status and renal function changes over a period of up to 7 years in 35 patients with renal impairment who had stage 3 or higher chronic kidney disease (CKD; stage 3 in 32 patients, stage 4 in 2 patients, and stage 5 in 1 patient) associated with hyperuricemia and were receiving monotherapy with benzbromarone as an antihyperuricemic drug." | 3.77 | Efficacy of benzbromarone in hyperuricemic patients associated with chronic kidney disease. ( Fujimori, S; Moromizato, H; Ooyama, H; Ooyama, K, 2011) |
| "Gouty arthritis is a metabolic disorder associated with hyperuricemia." | 1.40 | Successful treatment of refractory gout using combined therapy consisting of febuxostat and allopurinol in a patient with chronic renal failure. ( Aoki, T; Hishida, M; Maekawa, M; Morinaga, T; Tamai, H; Tomida, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maekawa, M | 1 |
| Tomida, H | 1 |
| Aoki, T | 1 |
| Hishida, M | 1 |
| Morinaga, T | 1 |
| Tamai, H | 1 |
| Fujimori, S | 1 |
| Ooyama, K | 1 |
| Ooyama, H | 1 |
| Moromizato, H | 1 |
| Caldas, CA | 1 |
| Fuller, R | 1 |
| Heidelmann, G | 1 |
| Burck, G | 1 |
| Dauterstedt, W | 1 |
| Heinrich, JJ | 1 |
| Ohlmer, R | 1 |
| Hisatome, I | 1 |
| Kosaka, H | 1 |
| Ohtahara, K | 1 |
| Tsuboi, M | 1 |
| Manabe, I | 1 |
| Ohtahara, A | 1 |
| Sawaguchi, M | 1 |
| Igawa, O | 1 |
| Tanaka, Y | 1 |
| Fujimoto, Y | 1 |
| Yoshida, A | 1 |
| Takeda, A | 1 |
| Shigemasa, C | 1 |
| Grahame, R | 1 |
| Simmonds, HA | 1 |
| McBride, MB | 1 |
| Marsh, FP | 1 |
| Lhotta, K | 1 |
| Gruber, J | 1 |
| Sgonc, R | 1 |
| Fend, F | 1 |
| König, P | 1 |
| Didier, M | 1 |
| Olmer, M | 1 |
| Bec, Ph | 1 |
| Pujo, JM | 1 |
| Suc, JM | 1 |
1 trial available for benzbromarone and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Hypouricemic effect of benzbromarone especially in kidney failure].
Topics: Adolescent; Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Depression, Chemical; | 1978 |
8 other studies available for benzbromarone and Kidney Failure, Chronic
| Article | Year |
|---|---|
Successful treatment of refractory gout using combined therapy consisting of febuxostat and allopurinol in a patient with chronic renal failure.
Topics: Adrenal Cortex Hormones; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Drug Therapy, Combinati | 2014 |
Efficacy of benzbromarone in hyperuricemic patients associated with chronic kidney disease.
Topics: Benzbromarone; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Kidney Failure, Chronic; M | 2011 |
Excellent response to the clinical treatment of tophaceous gout.
Topics: Aged; Allopurinol; Benzbromarone; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Kidne | 2007 |
[Indications for and methods of allopurinol-benzbromarone combination therapy in the treatment of hyperuricemic metabolic disorders].
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Drug Therapy, Combination; | 1982 |
Renal handling of urate in a patient with familial juvenile gouty nephropathy.
Topics: Adolescent; Benzbromarone; Female; Genes, Dominant; Gout; Gout Suppressants; Humans; Kidney; Kidney | 1996 |
How should we treat tophaceous gout in patients with allopurinol hypersensitivity?
Topics: Adolescent; Adult; Aged; Allopurinol; Benzbromarone; Creatinine; Drug Hypersensitivity; Gout; Gout S | 1998 |
Apoptosis of tubular epithelial cells in familial juvenile gouty nephropathy.
Topics: Adult; Apoptosis; Benzbromarone; Biopsy; Biotin; Deoxyuracil Nucleotides; DNA Fragmentation; Family | 1998 |
[Mechanisms of action of benzbromarone. Study in 3 anephric subjects. Preliminary results in 3 cases].
Topics: Adult; Benzbromarone; Benzofurans; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Failure, | 1977 |