benzbromarone has been researched along with Kidney Diseases in 15 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzbromarone1 is a benzofuran derivative which lowers serum urate and increases urinary urate excretion in normal, hyperuricaemic and gouty subjects." | 8.75 | Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| "A study was conducted to determine whether combination treatment using allopurinol and benzbromarone was more useful than single allopurinol treatment for the gout and hyperuricemia accompanying renal dysfunction." | 7.74 | [Usefulness of combination treatment using allopurinol and benzbromarone for gout and hyperuricemia accompanying renal dysfunction: kinetic analysis of oxypurinol]. ( Gomi, H; Hikita, M; Hosoya, T; Ichida, K; Ohno, I; Okabe, H; Saikawa, H; Uetake, D; Yamaguchi, Y, 2008) |
| "Benzbromarone1 is a benzofuran derivative which lowers serum urate and increases urinary urate excretion in normal, hyperuricaemic and gouty subjects." | 4.75 | Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| " The effect of preventing hyperuricemia was determined by concomitant treatment with a xanthine oxidase inhibitor, allopurinol (CsAALP), or with a uricosuric, benzbromarone (CsABENZ), in drinking water." | 3.78 | Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. ( Johnson, RJ; Mazali, FC; Mazzali, M, 2012) |
| "A study was conducted to determine whether combination treatment using allopurinol and benzbromarone was more useful than single allopurinol treatment for the gout and hyperuricemia accompanying renal dysfunction." | 3.74 | [Usefulness of combination treatment using allopurinol and benzbromarone for gout and hyperuricemia accompanying renal dysfunction: kinetic analysis of oxypurinol]. ( Gomi, H; Hikita, M; Hosoya, T; Ichida, K; Ohno, I; Okabe, H; Saikawa, H; Uetake, D; Yamaguchi, Y, 2008) |
| "Hematuria was seen in 7 out of the 16 patients (44%), all of whom were females (58%)." | 1.30 | Hematuria in patients with renal hypouricemia. ( Hamada, N; Hiroe, K; Hisatome, I; Kato, T; Kinugawa, T; Manabe, I; Ogino, K; Ohtahara, A; Sato, R; Shigemasa, C; Shimoyama, M; Takeda, A; Tanaka, Y; Tsuboi, M; Yamamoto, Y; Yoshida, A, 1998) |
| "Uric acid clearance was increased by benzbromarone from 3." | 1.26 | [The effect of benzbromaron in gout patients with limited kidney function]. ( Bresnik, W; Kuzmits, R; Müller, MM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ichida, K | 2 |
| Hosoyamada, M | 1 |
| Kimura, H | 1 |
| Takeda, M | 1 |
| Utsunomiya, Y | 1 |
| Hosoya, T | 2 |
| Endou, H | 1 |
| Ohno, I | 1 |
| Okabe, H | 1 |
| Yamaguchi, Y | 1 |
| Saikawa, H | 1 |
| Uetake, D | 1 |
| Hikita, M | 1 |
| Gomi, H | 1 |
| Mazali, FC | 1 |
| Johnson, RJ | 1 |
| Mazzali, M | 1 |
| Zhu, W | 1 |
| Pang, M | 1 |
| Dong, L | 1 |
| Huang, X | 1 |
| Wang, S | 1 |
| Zhou, L | 1 |
| Yamanaka, H | 1 |
| Lhotta, K | 1 |
| Hisatome, I | 3 |
| Tanaka, Y | 2 |
| Kotake, H | 2 |
| Kosaka, H | 1 |
| Hirata, N | 1 |
| Fujimoto, Y | 1 |
| Yoshida, A | 2 |
| Shigemasa, C | 2 |
| Mashiba, H | 2 |
| Sato, R | 2 |
| Ogino, K | 2 |
| Shimoyama, M | 1 |
| Hiroe, K | 1 |
| Tsuboi, M | 1 |
| Yamamoto, Y | 1 |
| Hamada, N | 1 |
| Kato, T | 1 |
| Manabe, I | 1 |
| Kinugawa, T | 1 |
| Ohtahara, A | 1 |
| Takeda, A | 1 |
| Gröbner, W | 1 |
| Walter-Sack, I | 1 |
| Heel, RC | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Kuzmits, R | 1 |
| Bresnik, W | 1 |
| Müller, MM | 1 |
| Siegenthaler-Zuber, G | 1 |
| Yamamoto, T | 1 |
| Moriwaki, Y | 1 |
| Takahashi, S | 1 |
| Suda, M | 1 |
| Agbedana, EO | 1 |
| Higashino, K | 1 |
| Saito, M | 1 |
| Miyamoto, J | 1 |
| Hasegawa, J | 1 |
| Nakamoto, S | 1 |
| Takeda, E | 1 |
| Kuroda, Y | 1 |
| Ito, M | 2 |
| Toshima, K | 1 |
| Watanabe, T | 1 |
| Naito, E | 1 |
| Yokota, I | 1 |
| Hwang, TJ | 1 |
| Miyao, M | 1 |
2 reviews available for benzbromarone and Kidney Diseases
| Article | Year |
|---|---|
[Drug therapy for idiopathic hyperuricemia--introduction, dose, and side effects].
Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Enzyme Inhibitors; Gout; Humans; Hyperuricemia; Kidney | 2003 |
Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia.
Topics: Aspirin; Benzbromarone; Benzofurans; Drug Interactions; Fasting; Gout; Humans; Kidney Diseases; Kine | 1977 |
13 other studies available for benzbromarone and Kidney Diseases
| Article | Year |
|---|---|
Urate transport via human PAH transporter hOAT1 and its gene structure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Biological Transport; Blotting, Western; Car | 2003 |
[Usefulness of combination treatment using allopurinol and benzbromarone for gout and hyperuricemia accompanying renal dysfunction: kinetic analysis of oxypurinol].
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Benzbromarone; Drug Therapy, Combination; Gout; Gout Su | 2008 |
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy.
Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis; | 2012 |
Anti-inflammatory and immunomodulatory effects of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats.
Topics: Actins; Allopurinol; Animals; Anti-Inflammatory Agents; Benzbromarone; Chemokine CCL2; Cyclopentane | 2012 |
Stopping progression in familial juvenile hyperuricemic nephropathy with benzbromarone?
Topics: Benzbromarone; Disease Progression; Humans; Hyperuricemia; Kidney Diseases; Uricosuric Agents | 2003 |
Renal hypouricemia due to enhanced tubular secretion of urate associated with urolithiasis: successful treatment of urolithiasis by alkalization of urine K+, Na(+)-citrate.
Topics: Benzbromarone; Citrates; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Ki | 1993 |
Hematuria in patients with renal hypouricemia.
Topics: Adult; Aged; Aged, 80 and over; Benzbromarone; Creatinine; Female; Hematuria; Humans; Kidney Disease | 1998 |
[Hyperuricemia and gout--treatment].
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug | 2002 |
[The effect of benzbromaron in gout patients with limited kidney function].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Creatinine; Drug Evaluation; Gout; Humans; Kidney Diseases; | 1979 |
[Which uric acid value is in need of treatment?].
Topics: Allopurinol; Benzbromarone; Citrates; Coronary Disease; Gout; Humans; Hyperlipidemias; Hypertension; | 1976 |
Two cases in whom pyrazinamide does not inhibit the uricosuric action of benzbromarone.
Topics: Adult; Benzbromarone; Diabetes Mellitus, Type 2; Drug Interactions; Female; Humans; Kidney; Kidney D | 1992 |
Renal hypouricemia due to an isolated renal defect of urate transport.
Topics: Adult; Benzbromarone; Humans; Kidney; Kidney Diseases; Male; Pyrazinamide; Uric Acid | 1988 |
Hereditary renal hypouricemia in children.
Topics: Benzbromarone; Child; Child, Preschool; Creatinine; Humans; Kidney Diseases; Kidney Tubules; Metabol | 1985 |