benzbromarone has been researched along with Inflammation in 6 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The data indicate that the development of atherosclerosis and inflammation is promoted by uric acid in vivo." | 7.96 | Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. ( Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T, 2020) |
| "The data indicate that the development of atherosclerosis and inflammation is promoted by uric acid in vivo." | 3.96 | Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. ( Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T, 2020) |
| "Fructose-fed rats showed hyperuricemia, abdominal obesity hypertension and an activation in adipose renin-angiotensin system (RAS)." | 1.62 | Hyperuricemia Inhibition Protects SD Rats Against Fructose-Induced Obesity Hypertension Via Modulation of Inflammation and Renin-Angiotensin System in Adipose Tissue. ( Lin, X; Tang, F; Xu, J; Zhang, JX, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Zhang, JX | 1 |
| Lin, X | 1 |
| Xu, J | 1 |
| Tang, F | 1 |
| Abdel-Razek, EA | 1 |
| Abo-Youssef, AM | 1 |
| Azouz, AA | 1 |
| Kimura, Y | 1 |
| Yanagida, T | 1 |
| Onda, A | 1 |
| Tsukui, D | 1 |
| Hosoyamada, M | 1 |
| Kono, H | 1 |
| Thounaojam, MC | 1 |
| Montemari, A | 1 |
| Powell, FL | 1 |
| Malla, P | 1 |
| Gutsaeva, DR | 1 |
| Bachettoni, A | 1 |
| Ripandelli, G | 1 |
| Repossi, A | 1 |
| Tawfik, A | 1 |
| Martin, PM | 1 |
| Facchiano, F | 1 |
| Bartoli, M | 1 |
| Zheng, Y | 1 |
| Xu, H | 1 |
| Zhan, L | 1 |
| Zhou, X | 1 |
| Chen, X | 1 |
| Gao, Z | 1 |
6 other studies available for benzbromarone and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Hyperuricemia Inhibition Protects SD Rats Against Fructose-Induced Obesity Hypertension Via Modulation of Inflammation and Renin-Angiotensin System in Adipose Tissue.
Topics: Adipose Tissue; Allopurinol; Animals; Benzbromarone; Diet, Carbohydrate Loading; Disease Models, Ani | 2021 |
Benzbromarone mitigates cisplatin nephrotoxicity involving enhanced peroxisome proliferator-activated receptor-alpha (PPAR-α) expression.
Topics: Animals; Antioxidants; Benzbromarone; Blood Urea Nitrogen; Cisplatin; Creatinine; Inflammation; Kidn | 2020 |
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Topics: Adult; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Benzbromarone; Biomarkers; Disease M | 2020 |
Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy.
Topics: Allopurinol; Animals; Benzbromarone; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; | 2019 |
Activation of peripheral KCNQ channels relieves gout pain.
Topics: Action Potentials; Animals; Animals, Newborn; Arthritis; Benzbromarone; Cells, Cultured; CHO Cells; | 2015 |