benzbromarone has been researched along with Fibrosis in 2 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High levels of serum uric acid is closely associated with atrial fibrillation (AF); nonetheless, the detailed mechanisms remain unknown." | 4.02 | Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications. ( Li, Y; Liang, D; Liang, Z; Liu, H; Liu, Y; Su, M; Sun, L; Wang, D; Wei, Y; Yin, S; Zhang, G; Zhang, S; Zhao, J, 2021) |
| " The effect of preventing hyperuricemia was determined by concomitant treatment with a xanthine oxidase inhibitor, allopurinol (CsAALP), or with a uricosuric, benzbromarone (CsABENZ), in drinking water." | 3.78 | Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. ( Johnson, RJ; Mazali, FC; Mazzali, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, D | 1 |
| Sun, L | 1 |
| Zhang, G | 1 |
| Liu, Y | 1 |
| Liang, Z | 1 |
| Zhao, J | 1 |
| Yin, S | 1 |
| Su, M | 1 |
| Zhang, S | 1 |
| Wei, Y | 1 |
| Liu, H | 1 |
| Liang, D | 1 |
| Li, Y | 1 |
| Mazali, FC | 1 |
| Johnson, RJ | 1 |
| Mazzali, M | 1 |
2 other studies available for benzbromarone and Fibrosis
| Article | Year |
|---|---|
Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications.
Topics: Actins; Animals; Apoptosis; Atrial Fibrillation; Atrial Remodeling; bcl-2-Associated X Protein; Benz | 2021 |
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy.
Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis; | 2012 |