benzbromarone has been researched along with Cardiomegaly in 1 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vascular remodeling is promoted by the survival and proliferation of pulmonary arterial vascular cells in a DNA-damaging, hostile microenvironment." | 1.51 | The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension. ( Hegde, RS; Hu, YC; Mallela, J; Molkentin, JD; Nichols, WC; Pandey, RN; Wang, Y; Wikenheiser-Brokamp, KA; York, AJ, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Pandey, RN | 1 |
| York, AJ | 1 |
| Mallela, J | 1 |
| Nichols, WC | 1 |
| Hu, YC | 1 |
| Molkentin, JD | 1 |
| Wikenheiser-Brokamp, KA | 1 |
| Hegde, RS | 1 |
1 other study available for benzbromarone and Cardiomegaly
| Article | Year |
|---|---|
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Topics: Animals; Apoptosis; Benzbromarone; Cardiomegaly; Cell Proliferation; Cell Survival; DNA Damage; DNA | 2019 |