benzbromarone has been researched along with Cardiac Hypertrophy in 1 studies
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vascular remodeling is promoted by the survival and proliferation of pulmonary arterial vascular cells in a DNA-damaging, hostile microenvironment." | 1.51 | The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension. ( Hegde, RS; Hu, YC; Mallela, J; Molkentin, JD; Nichols, WC; Pandey, RN; Wang, Y; Wikenheiser-Brokamp, KA; York, AJ, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Pandey, RN | 1 |
| York, AJ | 1 |
| Mallela, J | 1 |
| Nichols, WC | 1 |
| Hu, YC | 1 |
| Molkentin, JD | 1 |
| Wikenheiser-Brokamp, KA | 1 |
| Hegde, RS | 1 |
1 other study available for benzbromarone and Cardiac Hypertrophy
| Article | Year |
|---|---|
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Topics: Animals; Apoptosis; Benzbromarone; Cardiomegaly; Cell Proliferation; Cell Survival; DNA Damage; DNA | 2019 |