Page last updated: 2024-09-02

benzamil and Blood Pressure, High

benzamil has been researched along with Blood Pressure, High in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (30.00)18.2507
2000's9 (45.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersen, H; Hansen, PBL; Jacobsen, IA; Jensen, BL; Jürgensen, JF; Oxlund, CS; Peluso, AA; Staehr, M; Svenningsen, P; Vanhoutte, PM; Ydegaard, R1
Cowley, AW; Ilatovskaya, DV; Levchenko, V; Lombard, JH; Mattson, DL; Mori, T; O'Connor, PM; Palygin, O; Pavlov, TS; Sorokin, A; Staruschenko, A1
Carretero, OA; D'Ambrosio, MA; Garvin, JL; Ren, Y; Wang, H1
Gabor, A; Leenen, FH1
Amin, MS; Leenen, FH; Reza, E; Wang, H1
Aaronson, PI; Loutzenhiser, R1
Amin, MS; Leenen, FH; Van Huysse, JW; Yang, B1
Auberson, M; Hoffmann-Pochon, N; Kellenberger, S; Schild, L; Vandewalle, A1
Leenen, FH; Wang, H1
Huang, BS; Leenen, FH; Wang, H1
Hagiwara, Y; Kubo, T1
Butler, AA; Cone, RD; Humphreys, MH; Ni, XP1
Abrams, JM; Osborn, JW1
Gomez-Sanchez, CE; Gomez-Sanchez, EP2
Gómez Sánchez, EP1
Nanbu, A; Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M1
Betz, AL; Ennis, SR; Keep, RF; Shakui, P; Si, X1
Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M1
Hawk, CT; Schafer, JA1

Reviews

1 review(s) available for benzamil and Blood Pressure, High

ArticleYear
A role for benzamil-sensitive proteins of the central nervous system in the pathogenesis of salt-dependent hypertension.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:5-6

    Topics: Amiloride; Central Nervous System; Humans; Hypertension; Sodium Channel Blockers; Sodium Chloride

2008

Trials

1 trial(s) available for benzamil and Blood Pressure, High

ArticleYear
The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.
    Acta physiologica (Oxford, England), 2019, Volume: 225, Issue:1

    Topics: Acid Sensing Ion Channel Blockers; Amiloride; Animals; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endothelial Cells; Epithelial Sodium Channels; Gene Expression Regulation; Humans; Hypertension; Mice; Mice, Knockout; Nitric Oxide Synthase Type III

2019

Other Studies

18 other study(ies) available for benzamil and Blood Pressure, High

ArticleYear
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension.
    Journal of the American Society of Nephrology : JASN, 2013, Volume: 24, Issue:7

    Topics: Amiloride; Animals; Blood Pressure; Disease Models, Animal; Epidermal Growth Factor; Epithelial Sodium Channels; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary

2013
Connecting tubule glomerular feedback in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:4

    Topics: Amiloride; Animals; Blood Pressure; Hypertension; Kidney Glomerulus; Nephrons; Rats; Rats, Inbred Dahl; Vasoconstriction

2013
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cerebrospinal Fluid; Diuretics; Dose-Response Relationship, Drug; Eplerenone; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Ouabain; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Spironolactone

2009
Sodium transport in the choroid plexus and salt-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4

    Topics: Amiloride; Animals; Biological Transport; Choroid Plexus; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Male; Ouabain; Rats; Rats, Inbred Dahl; Rats, Wistar; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary

2009
Role of epithelial sodium channels in the renal myogenic response?
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Amiloride; Humans; Hypertension; Muscle, Smooth, Vascular; Renal Artery; Sodium Channel Blockers; Sodium Channels; Vasoconstriction

2010
Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Amiloride; Animals; Blood Pressure; Brain; Disease Models, Animal; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channels; Female; Heart Rate; Hypertension; Liddle Syndrome; Male; Mice; Mice, Knockout; Nedd4 Ubiquitin Protein Ligases; Sodium; Sodium Chloride, Dietary; Ubiquitin-Protein Ligases

2012
Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:3

    Topics: Aldosterone; Amiloride; Animals; Cell Line; Electric Conductivity; Epithelial Cells; Gene Expression; Humans; Hypertension; Mice; Mutation; Sodium Channels; Syndrome; Vasopressins

2003
Brain sodium channels and central sodium-induced increases in brain ouabain-like compound and blood pressure.
    Journal of hypertension, 2003, Volume: 21, Issue:8

    Topics: Amiloride; Animals; Blood Pressure; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Hypothalamus; Injections, Intraventricular; Male; Pituitary Gland; Rats; Rats, Wistar; Saponins; Sodium; Sodium Channels

2003
Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:6

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Brain Chemistry; Cardenolides; Digoxin; Heart Rate; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Wistar; Saponins; Sodium; Sodium Channels; Sympathetic Nervous System

2003
Enhanced central hypertonic saline-induced activation of angiotensin II-sensitive neurons in the anterior hypothalamic area of spontaneously hypertensive and Dahl S rats.
    Brain research bulletin, 2006, Jan-30, Volume: 68, Issue:5

    Topics: Action Potentials; Amiloride; Angiotensin II; Animals; Anterior Hypothalamic Nucleus; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; Hypertension; Male; Neurons; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Saline Solution, Hypertonic; Sodium; Vasoconstrictor Agents

2006
Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones.
    Journal of hypertension, 2006, Volume: 24, Issue:11

    Topics: alpha-MSH; Amiloride; Animals; Blood Pressure; Dose-Response Relationship, Drug; gamma-MSH; Heart Rate; Hypertension; Mice; Mice, Knockout; Models, Animal; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Sodium Channel Blockers; Sympatholytics

2006
Effect of central infusion of benzamil on Dahl S rat hypertension.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Amiloride; Animals; Brain; Drug Resistance; Hypertension; Injections, Intraventricular; Rats; Rats, Inbred Strains; Sodium Chloride

1995
Hypertension and the mineralocorticoid receptor in the brain.
    Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 746

    Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Blood Pressure; Brain; Cerebral Ventricles; Hippocampus; Hypertension; Infusions, Parenteral; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Mineralocorticoid; Spironolactone

1994
Effect of central amiloride infusion on mineralocorticoid hypertension.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 1

    Topics: Aldosterone; Amiloride; Animals; Brain; Carbenoxolone; Diet; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Male; Mineralocorticoids; Rats; Rats, Sprague-Dawley

1994
Benzamil blockade of brain Na+ channels averts Na(+)-induced hypertension in rats.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Amiloride; Animals; Arginine Vasopressin; Blood Pressure; Endothelin-1; Heart Rate; Hypertension; Injections, Intraventricular; Male; Natriuresis; Rats; Rats, Wistar; Saline Solution, Hypertonic; Sodium Channel Blockers

1998
Effect of amiloride analogs on DOCA-salt-induced hypertension in rats.
    The American journal of physiology, 1999, Volume: 276, Issue:6

    Topics: Amiloride; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride

1999
Role of FMRFamide-activated brain sodium channel in salt-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Amiloride; Anesthesia; Animals; Arginine Vasopressin; Blood Pressure; Brain Chemistry; DNA Primers; FMRFamide; Ganglia, Sympathetic; Gene Expression; Heart Rate; Hypertension; Injections, Intraventricular; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Channels; Sodium Chloride, Dietary

2000
Effects of AVP and deoxycorticosterone on Na+ and water transport in the Dahl salt-sensitive rat CCD.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2

    Topics: Absorption; Amiloride; Animals; Arginine Vasopressin; Body Water; Cell Membrane; Desoxycorticosterone; Drug Synergism; Hypertension; Kidney Tubules, Collecting; Kinetics; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Sodium, Dietary

1991