benzamide has been researched along with Melanoma in 3 studies
benzamide : An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we provide our experience with different labeling procedures for the radioiodination of benzamides and report on initial dosimetry data and the first therapeutic application of (131)I-BA52, a novel melanin-binding benzamide in patients with metastatic malignant melanoma." | 7.80 | Radiopharmaceutical therapy of patients with metastasized melanoma with the melanin-binding benzamide 131I-BA52. ( Babich, JW; Beijer, B; Eisenhut, M; Enk, A; Friebe, M; Giesel, FL; Haberkorn, U; Hassel, JC; Kratochwil, C; Mier, W, 2014) |
| " With the goal of selective delivery of the HDACi to melanoma cells, we incorporated the benzamide, a high affinity melanin-binding template, into the design of HDACi to generate a new series of compounds 10a-b and 11a-b which display high potency towards HDAC1 and HDAC6." | 3.85 | Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors. ( Ahluwalia, K; Oyelere, AK; Raji, I, 2017) |
| "Here we provide our experience with different labeling procedures for the radioiodination of benzamides and report on initial dosimetry data and the first therapeutic application of (131)I-BA52, a novel melanin-binding benzamide in patients with metastatic malignant melanoma." | 3.80 | Radiopharmaceutical therapy of patients with metastasized melanoma with the melanin-binding benzamide 131I-BA52. ( Babich, JW; Beijer, B; Eisenhut, M; Enk, A; Friebe, M; Giesel, FL; Haberkorn, U; Hassel, JC; Kratochwil, C; Mier, W, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mier, W | 1 |
| Kratochwil, C | 1 |
| Hassel, JC | 1 |
| Giesel, FL | 1 |
| Beijer, B | 1 |
| Babich, JW | 1 |
| Friebe, M | 1 |
| Eisenhut, M | 1 |
| Enk, A | 1 |
| Haberkorn, U | 1 |
| Divgi, C | 1 |
| Raji, I | 1 |
| Ahluwalia, K | 1 |
| Oyelere, AK | 1 |
3 other studies available for benzamide and Melanoma
| Article | Year |
|---|---|
Radiopharmaceutical therapy of patients with metastasized melanoma with the melanin-binding benzamide 131I-BA52.
Topics: Adult; Aged; Aged, 80 and over; Benzamides; Benzodioxoles; Female; Humans; Iodine Radioisotopes; Mal | 2014 |
Whither goest thou, radiopharmaceutical therapy?
Topics: Benzamides; Benzodioxoles; Female; Humans; Iodine Radioisotopes; Male; Melanins; Melanoma; Radiophar | 2014 |
Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors.
Topics: Acetylation; Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; | 2017 |