benzamide has been researched along with Diabetes Mellitus, Adult-Onset in 4 studies
benzamide : An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, YH-GKA exhibited high bioavailability and moderate elimination in preclinical species." | 1.39 | Discovery of a novel phenylethyl benzamide glucokinase activator for the treatment of type 2 diabetes mellitus. ( Choi, HH; Chong, W; Han, T; Kim, YH; Lee, BM; Lee, CH; Lee, DH; Park, K; Yi, W, 2013) |
| " Through modification of our initial lead 5, we have identified potent and selective 11beta-HSD1 inhibitors, such as 11n, which demonstrated improved glycemic control, decreased serum lipids, and enhanced insulin sensitivity when dosed ip in diabetic ob/ob mice." | 1.35 | 4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice. ( Chen, J; Du, L; Feng, Y; Leng, Y; Shen, J; Yang, H; Zhang, X; Zhou, Z, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rew, Y | 1 |
| McMinn, DL | 1 |
| Wang, Z | 1 |
| He, X | 1 |
| Hungate, RW | 1 |
| Jaen, JC | 1 |
| Sudom, A | 1 |
| Sun, D | 1 |
| Tu, H | 1 |
| Ursu, S | 1 |
| Villemure, E | 1 |
| Walker, NP | 1 |
| Yan, X | 1 |
| Ye, Q | 1 |
| Powers, JP | 1 |
| Zhang, X | 1 |
| Zhou, Z | 1 |
| Yang, H | 1 |
| Chen, J | 1 |
| Feng, Y | 1 |
| Du, L | 1 |
| Leng, Y | 1 |
| Shen, J | 1 |
| Park, K | 2 |
| Lee, BM | 1 |
| Kim, YH | 1 |
| Han, T | 1 |
| Yi, W | 1 |
| Lee, DH | 1 |
| Choi, HH | 1 |
| Chong, W | 1 |
| Lee, CH | 1 |
1 review available for benzamide and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Identification of YH-GKA, a novel benzamide glucokinase activator as therapeutic candidate for type 2 diabetes mellitus.
Topics: Animals; Benzamides; Diabetes Mellitus, Type 2; Enzyme Activators; Glucokinase; Humans; Hypoglycemic | 2012 |
3 other studies available for benzamide and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Benzamides; Crystallography, X-Ray; Diabetes Mellitus, | 2009 |
4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Benzamides; Blood Glucose; Diabetes Mellitus, | 2009 |
Discovery of a novel phenylethyl benzamide glucokinase activator for the treatment of type 2 diabetes mellitus.
Topics: Animals; Benzamides; Cells, Cultured; Diabetes Mellitus, Type 2; Drug Discovery; Enzyme Activation; | 2013 |