benzamide has been researched along with Brain Ischemia in 3 studies
benzamide : An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study is aimed at evaluating the functional and neuroprotective effect of benzamide, a poly-(ADP-ribose) polymerase (PARP) inhibitor on delayed neuronal death (DND) in hippocampus CA1 region and memory impairment following global cerebral ischemia (GCI) in a mouse model." | 7.74 | Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia. ( Katyal, A; Kumaran, D; Nair, RU; R, A; Udayabanu, M, 2008) |
| "The present study is aimed at evaluating the functional and neuroprotective effect of benzamide, a poly-(ADP-ribose) polymerase (PARP) inhibitor on delayed neuronal death (DND) in hippocampus CA1 region and memory impairment following global cerebral ischemia (GCI) in a mouse model." | 3.74 | Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia. ( Katyal, A; Kumaran, D; Nair, RU; R, A; Udayabanu, M, 2008) |
| " We examined the neuroprotective effects of the PARP inhibitors benzamide, 6(5H)-phenanthridinone, and 3,4-dihydro-5-[4-1(1-piperidinyl)buthoxy]-1(2H)-isoquinolinone in three rodent models of cerebral ischemia." | 3.71 | Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia. ( Chiarugi, A; Cozzi, A; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F; Picca, R; Romagnoli, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferraris, D | 1 |
| Ko, YS | 1 |
| Pahutski, T | 1 |
| Ficco, RP | 1 |
| Serdyuk, L | 1 |
| Alemu, C | 1 |
| Bradford, C | 1 |
| Chiou, T | 1 |
| Hoover, R | 1 |
| Huang, S | 1 |
| Lautar, S | 1 |
| Liang, S | 1 |
| Lin, Q | 1 |
| Lu, MX | 1 |
| Mooney, M | 1 |
| Morgan, L | 1 |
| Qian, Y | 1 |
| Tran, S | 1 |
| Williams, LR | 1 |
| Wu, QY | 1 |
| Zhang, J | 1 |
| Zou, Y | 1 |
| Kalish, V | 1 |
| Kumaran, D | 1 |
| Udayabanu, M | 1 |
| Nair, RU | 1 |
| R, A | 1 |
| Katyal, A | 1 |
| Moroni, F | 1 |
| Meli, E | 1 |
| Peruginelli, F | 1 |
| Chiarugi, A | 1 |
| Cozzi, A | 1 |
| Picca, R | 1 |
| Romagnoli, P | 1 |
| Pellicciari, R | 1 |
| Pellegrini-Giampietro, DE | 1 |
3 other studies available for benzamide and Brain Ischemia
| Article | Year |
|---|---|
Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries.
Topics: Animals; Aza Compounds; Brain Ischemia; Dogs; Enzyme Inhibitors; Haplorhini; Humans; In Vitro Techni | 2003 |
Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia.
Topics: Animals; Apoptosis; Arterial Occlusive Diseases; Avoidance Learning; Behavior, Animal; Benzamides; B | 2008 |
Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia.
Topics: Animals; Apoptosis; Benzamides; Brain Ischemia; Caspase 3; Caspases; Cell Death; Cell Line; Cerebral | 2001 |