benserazide has been researched along with Schizophrenia in 9 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
Excerpt | Relevance | Reference |
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" In both men and women there tended to be a significant correlation between the initial log plasma PRL level while on neuroleptic maintenance treatment and the dosage received converted to chlorpromazine equivalents." | 2.65 | Lack of tolerance to long-term neuroleptic treatment in dopamine tuberoinfundibular system. ( Annable, L; Chouinard, G; Collu, R; Jones, BD, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (88.89) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (11.11) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ostrovskaya, RU | 1 |
Retyunskaya, MV | 1 |
Bondarenko, NA | 1 |
Gudasheva, TA | 1 |
Bobkova, NV | 1 |
Samokhin, AN | 1 |
Chouinard, G | 4 |
Annable, L | 3 |
Jones, BD | 2 |
Collu, R | 1 |
Casey, DE | 1 |
Gerlach, J | 2 |
Bjørndal, N | 1 |
Young, SN | 2 |
Gauthier, S | 1 |
Anderson, GM | 1 |
Purdy, WC | 1 |
Lühdorf, K | 1 |
Chouinard, Q | 1 |
Sourkes, TL | 1 |
Serrano, M | 1 |
Charette, R | 1 |
Matussek, N | 1 |
6 trials available for benserazide and Schizophrenia
Article | Year |
---|---|
Lack of tolerance to long-term neuroleptic treatment in dopamine tuberoinfundibular system.
Topics: Adult; Aged; Antipsychotic Agents; Benserazide; Chlorpromazine; Clinical Trials as Topic; Dose-Respo | 1981 |
The effect of L-dopa on young patients with simple schizophrenia, treated with neuroleptic drugs: a double-blind cross-over trial with Madopar and placebo.
Topics: Adult; Affect; Antipsychotic Agents; Anxiety; Basal Ganglia Diseases; Benserazide; Brief Psychiatric | 1975 |
A controlled study of tryptophan-benserazide in schizophrenia.
Topics: Adult; Aged; Benserazide; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therap | 1978 |
Evidence of brain dopamine deficiency in schizophrenia.
Topics: Benserazide; Brain; Chlorpromazine; Dopamine; Double-Blind Method; Drug Therapy, Combination; Humans | 1979 |
A controlled study of a dopa decarboxylase inhibitor (benserazide) in the treatment of schizophrenic patients.
Topics: Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Chlorpromazine; Female; Humans; Hy | 1977 |
Clinical and animal experiments concerning the function of brain catecholamines.
Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Ca | 1971 |
3 other studies available for benserazide and Schizophrenia
Article | Year |
---|---|
Cholinopositive effect of dilept (neurotensin peptidomimetic) as the basis of its mnemotropic effect.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Benserazide; Drug Combinations; Levodopa; Male; Memo | 2005 |
Levodopa and receptor sensitivity modification in tardive dyskinesia.
Topics: Adult; Aged; Antipsychotic Agents; Benserazide; Bipolar Disorder; Dementia; Dose-Response Relationsh | 1982 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; | 1982 |