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benserazide and Pulmonary Fibrosis

benserazide has been researched along with Pulmonary Fibrosis in 2 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
"A 64-year-old man was diagnosed to have Parkinson's disease when aged 42 years and since then has been treated with levodopa and benserazide (up to 875 mg daily)."1.29[Bromocriptine-induced pleuropneumopathy]. ( Eberli, F; Greminger, P; Schmid, PA; Speich, R; Suter, T, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmid, PA1
Suter, T1
Speich, R1
Eberli, F1
Greminger, P1
Todman, DH1
Oliver, WA1
Edwards, RL1

Other Studies

2 other studies available for benserazide and Pulmonary Fibrosis

ArticleYear
[Bromocriptine-induced pleuropneumopathy].
    Deutsche medizinische Wochenschrift (1946), 1994, Nov-11, Volume: 119, Issue:45

    Topics: Benserazide; Biperiden; Bromocriptine; Humans; Levodopa; Lung Diseases; Male; Middle Aged; Parkinson

1994
Pleuropulmonary fibrosis due to bromocriptine treatment for Parkinson's disease.
    Clinical and experimental neurology, 1990, Volume: 27

    Topics: Aged; Benserazide; Bromocriptine; Drug Therapy, Combination; Humans; Levodopa; Male; Middle Aged; Pa

1990