benserazide has been researched along with Pregnancy in 11 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amantadine has been teratogenic in rats and selegiline has caused neurochemical and behavioral alterations in rats when coadministered with clorgyline." | 2.40 | Pregnancy in Parkinson's disease: a review of the literature and a case report. ( Hagell, P; Odin, P; Vinge, E, 1998) |
| "Renal fibrosis is mediated by the accumulation of myofibroblasts, whereas renal anemia is mediated by the reduced production of fibroblast-derived erythropoietin, a hormone that stimulates erythropoiesis." | 1.37 | Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. ( Asada, M; Asada, N; Fehling, HJ; Fukatsu, A; Kimura, T; Kita, T; Minegishi, N; Nagoshi, N; Nakamura, J; Oguchi, A; Okano, H; Rao, TN; Shibata, S; Suzuki, N; Takase, M; Yamamoto, M; Yamamura, K; Yanagita, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asada, N | 1 |
| Takase, M | 1 |
| Nakamura, J | 1 |
| Oguchi, A | 1 |
| Asada, M | 1 |
| Suzuki, N | 1 |
| Yamamura, K | 1 |
| Nagoshi, N | 1 |
| Shibata, S | 1 |
| Rao, TN | 1 |
| Fehling, HJ | 1 |
| Fukatsu, A | 1 |
| Minegishi, N | 1 |
| Kita, T | 1 |
| Kimura, T | 1 |
| Okano, H | 1 |
| Yamamoto, M | 1 |
| Yanagita, M | 1 |
| Pontiroli, AE | 1 |
| Loda, G | 1 |
| Roggia, A | 1 |
| Scagliola, P | 1 |
| Falsetti, L | 1 |
| Mattheij, JA | 1 |
| Brouwer, GM | 1 |
| Hanstede, JG | 1 |
| Swarts, JJ | 1 |
| Arai, H | 1 |
| Shinotoh, H | 1 |
| Hattori, T | 1 |
| Hagell, P | 1 |
| Odin, P | 1 |
| Vinge, E | 1 |
| Routiot, T | 1 |
| Lurel, S | 1 |
| Denis, E | 1 |
| Barbarino-Monnier, P | 1 |
| Breese, GR | 1 |
| Vogel, RA | 1 |
| Kuhn, CM | 1 |
| Mailman, RB | 1 |
| Mueller, RA | 1 |
| Schanberg, SM | 1 |
| Wiggins, JF | 1 |
| Fernstrom, JD | 1 |
| Linnoila, M | 1 |
| Cooper, RL | 1 |
| Burke, RE | 1 |
| Reches, A | 1 |
| Allain, H | 1 |
| Bentue-Ferrer, D | 1 |
| Milon, D | 1 |
| Moran, P | 1 |
| Jacquemard, F | 1 |
| Defawe, G | 1 |
2 reviews available for benserazide and Pregnancy
| Article | Year |
|---|---|
Pregnancy in Parkinson's disease: a review of the literature and a case report.
Topics: Abnormalities, Drug-Induced; Adjuvants, Pharmaceutic; Adult; Amantadine; Animals; Antiparkinson Agen | 1998 |
[Parkinson's disease and pregnancy: case report and literature review].
Topics: Adult; Antiparkinson Agents; Benserazide; Drug Combinations; Female; Humans; Infant, Newborn; Levodo | 2000 |
9 other studies available for benserazide and Pregnancy
| Article | Year |
|---|---|
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice.
Topics: Anemia; Animals; Benserazide; Cell Differentiation; Cell Lineage; Disease Models, Animal; Drug Combi | 2011 |
Benserazide and nomifensine in the diagnosis of prolactin-secreting pituitary adenomas.
Topics: Adenoma; Benserazide; Female; Humans; Hydrazines; Isoquinolines; Nomifensine; Pituitary Neoplasms; P | 1982 |
No evidence for a peripheral effect of L-DOPA on plasma prolactin in the rat.
Topics: Animals; Benserazide; Female; Lactation; Levodopa; Male; Pregnancy; Prolactin; Rats; Sheep | 1982 |
[L-dopa/benserazide during pregnancy in a patient with juvenile parkinsonism].
Topics: Adult; Animals; Antiparkinson Agents; Benserazide; Carbonic Anhydrase Inhibitors; Drug Therapy, Comb | 1997 |
Behavioral and prolactin responses to 5-hydroxytryptophan in rats treated during development with 5,7-dihydroxytryptamine.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Behavior, Animal; Benserazi | 1978 |
L-Dopa inhibits prolactin secretion in proestrous rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Female; Levodopa; Pre | 1977 |
Reinstatement of vaginal cycles in aged female rats.
Topics: Aging; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Estrus; | 1976 |
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; B | 1991 |
Pregnancy and parkinsonism. A case report without problem.
Topics: Adult; Benserazide; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Parkinson Disease; | 1989 |