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benserazide and Pain

benserazide has been researched along with Pain in 3 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Forty-seven outpatients with herpes zoster, seen within five days of onset of the eruption, received ten days' administration of oral levodopa and benserazide or placebo in a double-blind controlled study."9.05Administration of levodopa for relief of herpes zoster pain. ( Hauchecorne, J; Kernbaum, S, 1981)
"Forty-seven outpatients with herpes zoster, seen within five days of onset of the eruption, received ten days' administration of oral levodopa and benserazide or placebo in a double-blind controlled study."5.05Administration of levodopa for relief of herpes zoster pain. ( Hauchecorne, J; Kernbaum, S, 1981)
"A number of patients with Parkinson's disease complain of severe and distressing pain."1.27Painful Parkinson's disease. ( Koller, WC; Lang, AE; Marsden, CD; Quinn, NP, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimizu, T1
Iwata, S1
Morioka, H1
Masuyama, T1
Fukuda, T1
Nomoto, M1
Kernbaum, S1
Hauchecorne, J1
Quinn, NP1
Koller, WC1
Lang, AE1
Marsden, CD1

Trials

1 trial available for benserazide and Pain

ArticleYear
Administration of levodopa for relief of herpes zoster pain.
    JAMA, 1981, Jul-10, Volume: 246, Issue:2

    Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination;

1981

Other Studies

2 other studies available for benserazide and Pain

ArticleYear
Antinociceptive mechanism of L-DOPA.
    Pain, 2004, Volume: 110, Issue:1-2

    Topics: Animals; Behavior, Animal; Benserazide; Benzazepines; Dopamine; Dopamine Agents; Dose-Response Relat

2004
Painful Parkinson's disease.
    Lancet (London, England), 1986, Jun-14, Volume: 1, Issue:8494

    Topics: Acute Disease; Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Administration Schedu

1986