Page last updated: 2024-10-23

benserazide and Nervous System Disorders

benserazide has been researched along with Nervous System Disorders in 3 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dill, P1
Wagner, M1
Somerville, A1
Thöny, B1
Blau, N1
Weber, P1
Martinez-Campos, A1
Giovannini, P1
Cocchi, D1
Zanardi, P1
Parati, EA1
Caraceni, T1
Müller, EE1
Azuma, T1
Suzuki, T1
Sakoda, S1
Mizuno, R1
Tsujino, S1
Kobayashi, T1
Kishimoto, S1
Hiraga, T1
Matsubara, T1
Yoshida, S1

Reviews

1 review available for benserazide and Nervous System Disorders

ArticleYear
Growth hormone secretion in neurological disorders.
    Advances in biochemical psychopharmacology, 1981, Volume: 28

    Topics: Benserazide; Disease Models, Animal; Dopamine; Growth Hormone; Humans; Huntington Disease; Levodopa;

1981

Other Studies

2 other studies available for benserazide and Nervous System Disorders

ArticleYear
Child neurology: paroxysmal stiffening, upward gaze, and hypotonia: hallmarks of sepiapterin reductase deficiency.
    Neurology, 2012, Jan-31, Volume: 78, Issue:5

    Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Behavior; Benserazide; Consanguinity; Developmental Di

2012
Effect of long-term L-threo-3,4-dihydroxyphenylserine administration on alpha 2-adrenergic receptors in platelet membranes in neurologic disorders.
    Acta neurologica Scandinavica, 1991, Volume: 84, Issue:1

    Topics: Aged; Amyloidosis; Benserazide; Blood Platelets; Dose-Response Relationship, Drug; Droxidopa; Drug T

1991