benserazide has been researched along with Hypoxia in 7 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with benserazide (20 mg/kg i." | 5.26 | Cardiovascular responses to acute hypoxia in dogs pretreated with benserazide and L-DOPA. ( Boismare, F; Hacpille, L; Le Poncin, M, 1976) |
| "Pretreatment by benserazide (50 mg/kg i." | 5.25 | Reduction of hypoxia-induced disturbances by previous treatment with benserazide and L-dopa in rats. ( Belliard, JP; Boismare, F; Hacpille, L; le Poncin, M, 1975) |
| "Postanoxic myoclonus was first accepted as being related to a dysfunction of the ventrolateral thalamic nucleus." | 1.26 | Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor. ( Beretta, E; de Crousaz, G; Regli, F; Steck, AJ, 1981) |
| "Pretreatment with benserazide (20 mg/kg i." | 1.26 | Cardiovascular responses to acute hypoxia in dogs pretreated with benserazide and L-DOPA. ( Boismare, F; Hacpille, L; Le Poncin, M, 1976) |
| "Pretreatment by benserazide (50 mg/kg) and L." | 1.25 | [Effect of L-dopa combined with benserazide on hemodynamics and motor activity in hypoxic rats]. ( Belliard, JP; Boismare, F; Hacpille, L; Le Poncin, M, 1975) |
| "Pretreatment by benserazide (50 mg/kg i." | 1.25 | Reduction of hypoxia-induced disturbances by previous treatment with benserazide and L-dopa in rats. ( Belliard, JP; Boismare, F; Hacpille, L; le Poncin, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beretta, E | 1 |
| Regli, F | 1 |
| de Crousaz, G | 1 |
| Steck, AJ | 1 |
| Meerson, FZ | 1 |
| Mamalyga, LM | 1 |
| Boismare, F | 3 |
| Le Poncin, M | 3 |
| Belliard, JP | 2 |
| Hacpille, L | 3 |
| Burke, RE | 1 |
| Reches, A | 1 |
| Carlsson, A | 1 |
1 review available for benserazide and Hypoxia
| Article | Year |
|---|---|
Measurements of monoamine synthesis and turnover with special reference to 5-hydroxytryptamine.
Topics: Acetamides; Animals; Benserazide; Benzyl Compounds; Biogenic Amines; Brain; Carboxy-Lyases; Dibenzaz | 1974 |
6 other studies available for benserazide and Hypoxia
| Article | Year |
|---|---|
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middl | 1981 |
[The protective action of adaptation to hypoxia in audiogenic epilepsy and its prolongation by using pharmacologic agents].
Topics: Acoustic Stimulation; Adaptation, Physiological; Animals; Benserazide; Brain; Brain Chemistry; Drug | 1994 |
[Effect of L-dopa combined with benserazide on hemodynamics and motor activity in hypoxic rats].
Topics: Animals; Benserazide; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Heart Rat | 1975 |
Cardiovascular responses to acute hypoxia in dogs pretreated with benserazide and L-DOPA.
Topics: Animals; Benserazide; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodyna | 1976 |
Reduction of hypoxia-induced disturbances by previous treatment with benserazide and L-dopa in rats.
Topics: Animals; Benserazide; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circulation; Dopamine; Female | 1975 |
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; B | 1991 |