benserazide has been researched along with Drug Withdrawal Symptoms in 7 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Excerpt | Relevance | Reference |
---|---|---|
"Levodopa treatment might change the dopaminergic and serotoninergic neuronal systems, but not the noradrenergic or adrenergic neuronal systems, in CNS of PD patients." | 1.29 | Monoamines and their metabolites in plasma and lumbar cerebrospinal fluid of Chinese patients with Parkinson's disease. ( Cheng, FC; Chia, LG; Kuo, JS, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (42.86) | 18.7374 |
1990's | 3 (42.86) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Casseron, W | 1 |
Genton, P | 1 |
Bailey, R | 1 |
Crisp, E | 1 |
Jackson, DM | 1 |
Jenkins, O | 1 |
Kukuev, LA | 1 |
Sergutina, AV | 1 |
Gershteĭn, LM | 1 |
Olivé, JM | 1 |
Masana, L | 1 |
González, J | 1 |
Chia, LG | 1 |
Cheng, FC | 1 |
Kuo, JS | 1 |
Kuschinsky, K | 1 |
Herz, A | 1 |
Bläsig, J | 1 |
Papeschi, R | 1 |
7 other studies available for benserazide and Drug Withdrawal Symptoms
Article | Year |
---|---|
DOPA-sensitive dystonia-plus syndrome.
Topics: Adolescent; Benserazide; Brain; Child; Child Behavior Disorders; Child, Preschool; Craniofacial Abno | 2005 |
Chronic L-DOPA treatment of mice: a behavioural and biochemical study.
Topics: Animals; Apomorphine; Benserazide; Body Temperature Regulation; Brain; Clonidine; Dihydroxyphenylala | 1981 |
[Pathochemical changes in the motor structures of the brain under the influence of the administration of L-DOPA preparations and their withdrawal (experimental research)].
Topics: Animals; Benserazide; Brain; Brain Chemistry; Drug Combinations; Histocytochemistry; Levodopa; Rats; | 1994 |
Meperidine and reversible parkinsonism.
Topics: Adult; Benserazide; Drug Therapy, Combination; Humans; Levodopa; Male; Meperidine; Neurologic Examin | 1994 |
Monoamines and their metabolites in plasma and lumbar cerebrospinal fluid of Chinese patients with Parkinson's disease.
Topics: Aged; Benserazide; Biogenic Monoamines; China; Chromatography, High Pressure Liquid; Female; Humans; | 1993 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levo | 1975 |
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Brain Chemistry; Catecholamines; Cocaine; Desip | 1974 |