Page last updated: 2024-10-23

benserazide and Bruxism

benserazide has been researched along with Bruxism in 2 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Bruxism: A disorder characterized by grinding and clenching of the teeth.

Research Excerpts

ExcerptRelevanceReference
"The putative role of the dopaminergic system in sleep bruxism (SB) was studied in a double-blind clinical trial by using low doses of short-term L-dopa in combination with benserazide."5.08The effect of catecholamine precursor L-dopa on sleep bruxism: a controlled clinical trial. ( Lavigne, GJ; Lobbezoo, F; Montplaisir, JY; Tanguay, R, 1997)
"Experimental bruxism, audible, nonfunctional grinding or clenching of the teeth, was provoked in aggressive animals by drugs affecting central dopaminergic systems."1.26Experimental aggression and bruxism in rats. ( Pohto, P, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lobbezoo, F1
Lavigne, GJ1
Tanguay, R1
Montplaisir, JY1
Pohto, P1

Trials

1 trial available for benserazide and Bruxism

ArticleYear
The effect of catecholamine precursor L-dopa on sleep bruxism: a controlled clinical trial.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:1

    Topics: Adult; Benserazide; Bruxism; Cross-Over Studies; Dopamine Agents; Dose-Response Relationship, Drug;

1997

Other Studies

1 other study available for benserazide and Bruxism

ArticleYear
Experimental aggression and bruxism in rats.
    Acta odontologica Scandinavica, 1979, Volume: 37, Issue:2

    Topics: Aggression; Animals; Apomorphine; Benserazide; Bruxism; Ditiocarb; Electroshock; Humans; Iproniazid;

1979