benserazide has been researched along with Brain Ischemia in 5 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Odinak, MM | 1 |
| Vozniuk, IA | 1 |
| Kovalenko, PA | 1 |
| Lobzin, SV | 1 |
| Ianishevskiĭ, SN | 1 |
| Lee, TH | 2 |
| Abe, K | 2 |
| Nakamura, M | 2 |
| Kogure, K | 2 |
| Itoyama, Y | 2 |
| Tison, F | 1 |
| Duché, B | 1 |
| Loiseau, P | 1 |
| Aoki, M | 1 |
| Burke, RE | 1 |
| Reches, A | 1 |
1 review available for benserazide and Brain Ischemia
| Article | Year |
|---|---|
[Vascular hemi-parkinson disease].
Topics: Aged; Aspirin; Benserazide; Brain Ischemia; Drug Therapy, Combination; Female; Functional Laterality | 1993 |
1 trial available for benserazide and Brain Ischemia
| Article | Year |
|---|---|
[Madopar in the complex therapy of ischemic insult].
Topics: Aged; Aged, 80 and over; Benserazide; Blood Pressure; Brain Ischemia; Cognition; Dopamine Agents; Dr | 2005 |
3 other studies available for benserazide and Brain Ischemia
| Article | Year |
|---|---|
Reduction of nerve growth factor receptor immunoreactivity in ischaemic gerbil hippocampal CA1 neurons after treatment with L-threo-3,4-dihydroxyphenylserine (DOPS).
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blotting, Western; Brain Ischemi | 1994 |
The protective effect of L-threo-3,4-dihydroxyphenylserine on ischemic hippocampal neuronal death in gerbils.
Topics: Animals; Benserazide; Brain Ischemia; Cell Death; Droxidopa; Gerbillinae; Heat-Shock Proteins; Hippo | 1994 |
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; B | 1991 |