Page last updated: 2024-10-23

benserazide and Anochlesia

benserazide has been researched along with Anochlesia in 11 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Research Excerpts

ExcerptRelevanceReference
"The mice developed catalepsy after 3 weeks on the LCa/Mg diet."1.39Combined low calcium and lack magnesium is a risk factor for motor deficit in mice. ( Nakagawasai, O; Nemoto, W; Sato, S; Tadano, T; Tan-no, K; Taniguchi, R; Yamadera, F; Yaoita, F, 2013)
"KF17837 also reduced the catalepsy induced by haloperidol (1 mg/kg i."1.29KF17837: a novel selective adenosine A2A receptor antagonist with anticataleptic activity. ( Kanda, T; Nakamura, J; Shimada, J; Shiozaki, S; Suzuki, F, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's5 (45.45)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gołembiowska, K1
Dziubina, A1
Kowalska, M1
Kamińska, K1
Taniguchi, R1
Nakagawasai, O1
Tan-no, K1
Yamadera, F1
Nemoto, W1
Sato, S1
Yaoita, F1
Tadano, T1
Eltayb, A1
Wadenberg, ML2
Svensson, TH1
Himori, N2
Mishima, K2
Kanda, T1
Shiozaki, S1
Shimada, J1
Suzuki, F1
Nakamura, J1
Tanaka, Y1
Kurasawa, M1
Akaike, N1
Verhagen-Kamerbeek, WD1
Hazemeijer, I1
Korf, J1
Lakke, JP1
Ahlenius, S1
Bhattacharya, SK1
Parmar, SS1
Aizenstein, ML1
Scavone, C1
Steinschreiber, S1
de-Lucia, R1
Cashin, CH1
Sutton, S1

Other Studies

11 other studies available for benserazide and Anochlesia

ArticleYear
Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum.
    Neurotoxicity research, 2009, Volume: 15, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Area Under Curve; Benser

2009
Combined low calcium and lack magnesium is a risk factor for motor deficit in mice.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:2

    Topics: Amantadine; Animals; Antiparkinson Agents; Benserazide; Bromocriptine; Calcium; Catalepsy; Dopamine

2013
Enhanced cortical dopamine output and antipsychotic-like effect of raclopride with adjunctive low-dose L-dopa.
    Biological psychiatry, 2005, Aug-15, Volume: 58, Issue:4

    Topics: Analysis of Variance; Animals; Avoidance Learning; Benserazide; Catalepsy; Dopamine; Dopamine Agents

2005
The COMT inhibitor tolcapone potentiates the anticataleptic effect of Madopar in MPP(+)-lesioned mice.
    Experientia, 1994, Oct-15, Volume: 50, Issue:10

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Benserazide; Benzophenones; Catalepsy; Catechol O-Methyltransf

1994
KF17837: a novel selective adenosine A2A receptor antagonist with anticataleptic activity.
    European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3

    Topics: Adenosine; Administration, Oral; Animals; Antihypertensive Agents; Benserazide; Catalepsy; Dose-Resp

1994
3-O-methyldopa attenuates the effects of Madopar on the haloperidol-induced cataleptic behavior and the locomotor activity in the mouse.
    Pharmacology, 1994, Volume: 48, Issue:4

    Topics: Animals; Benserazide; Catalepsy; Drug Combinations; Haloperidol; Levodopa; Male; Mice; Motor Activit

1994
Attenuation of haloperidol-induced catalepsy by noradrenaline and L-threo-DOPS.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzophenones; Catalepsy; Catech

1993
Antagonism by the 5-HT2A/C receptor agonist DOI of raclopride-induced catalepsy in the rat.
    European journal of pharmacology, 1995, Dec-27, Volume: 294, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Benserazide; Benzazepines; Catalepsy; Dopamine Agents; D

1995
Stress by restraining potentiates morphine catalepsy in rats.
    Experientia, 1985, Dec-15, Volume: 41, Issue:12

    Topics: 5,6-Dihydroxytryptamine; Animals; Benserazide; Catalepsy; Diclofenac; Ditiocarb; Drug Interactions;

1985
Differential changes in dopaminergic receptor sensitivity induced by agonist drugs.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1985, Volume: 18, Issue:4

    Topics: Animals; Apomorphine; Benserazide; Brain Chemistry; Catalepsy; Drug Therapy, Combination; Haloperido

1985
The effect of anti-Parkinson drugs on catalepsy induced by -methyl-p-tyrosine in rats pretreated with intraventricular 6-hydroxydopamine.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Amantadine; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Benztropine; Brain

1973