benserazide has been researched along with Anemia, Hemolytic, Autoimmune in 3 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Reduction of levodopa dosage to one sixth with the aid of a peripheral decarboxylase inhibitor (benserazide) largely eliminated autoimmune haemolysis while maintaining adequate control of neurologic symptoms." | 1.26 | Dose-related levodopa-induced haemolytic anaemia. ( Enström, MS; Liedén, G; Linström, FD, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Linström, FD | 1 |
| Liedén, G | 1 |
| Enström, MS | 1 |
| Conte, P | 1 |
| Moulinier, J | 1 |
| Reiffers, J | 1 |
| Julien, J | 1 |
| Jyoichi, T | 1 |
| Sato, S | 1 |
| Yasuda, K | 1 |
| Kobayashi, M | 1 |
| Shimojyo, S | 1 |
| Ogura, Y | 1 |
| Miyahara, T | 1 |
3 other studies available for benserazide and Anemia, Hemolytic, Autoimmune
| Article | Year |
|---|---|
Dose-related levodopa-induced haemolytic anaemia.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Benserazide; Dose-Response Relationship, Drug; | 1977 |
["Immune type" haemolysis in course of L. dopa-benserazide therapeutic (author's transl)].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Benserazide; Coombs Test; Female; Humans; Hydrazines; Levodopa; | 1979 |
[A case of L-dopa induced autoimmune hemolytic anemida].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Benserazide; Humans; Levodopa; Male; Parkinson Disease | 1985 |