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benserazide and Aging

benserazide has been researched along with Aging in 8 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The aim of our study was to assess the frailty phenotype prevalence in geriatric inpatients with mild parkinsonian signs (MPS) and to investigate levodopa test in the frail patients with MPS."1.46Frailty phenotype and the role of levodopa challenge test in geriatric inpatients with mild parkinsonian signs. ( Bugdol, M; Czernek, M; Derejczyk, J; Kapko, W; Kawa, J; Marcisz, C; Seiffert, P; Stępień-Wyrobiec, O; Szymszal, J; Torbus, A, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seiffert, P1
Derejczyk, J1
Kawa, J1
Marcisz, C1
Czernek, M1
Szymszal, J1
Kapko, W1
Bugdol, M1
Torbus, A1
Stępień-Wyrobiec, O1
Kavaliers, M1
Hirst, M1
Teskey, GC1
Jensen, EW1
Eldrup, E1
Kelbaek, H1
Nielsen, SL1
Christensen, NJ1
Brus, R1
Linnoila, M1
Cooper, RL1
Kellogg, C1
Ossowska, K1
Schulze, G1
Wolfarth, S1
Coper, H1
Kaminska, A1
Hausmanowa-Petrusewicz, I1
Da Prada, M1

Reviews

1 review available for benserazide and Aging

ArticleYear
New approaches to the treatment of age-related brain disorders.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1991, Volume: 18, Issue:3 Suppl

    Topics: Aging; Alzheimer Disease; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Drug

1991

Other Studies

7 other studies available for benserazide and Aging

ArticleYear
Frailty phenotype and the role of levodopa challenge test in geriatric inpatients with mild parkinsonian signs.
    Biogerontology, 2017, Volume: 18, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Benserazide; Case-Control Studies; Cross-Sectional Stud

2017
Ageing, opioid analgesia and the pineal gland.
    Life sciences, 1983, May-09, Volume: 32, Issue:19

    Topics: Aging; Analgesia; Animals; Benserazide; Circadian Rhythm; Endorphins; Latency Period, Psychological;

1983
Venous plasma noradrenaline increases with age: correlation to total blood volume and long-term smoking habits.
    Clinical physiology (Oxford, England), 1993, Volume: 13, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Aging; Benserazide; Blood Volume; Bo

1993
Activity of some enzymes which synthesize and metabolize catecholamines in the brain and peripheral organs in developing rats.
    Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:4

    Topics: Adrenal Glands; Age Factors; Aging; Animals; Animals, Newborn; Benserazide; Brain; Catecholamines; D

1975
Reinstatement of vaginal cycles in aged female rats.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:2

    Topics: Aging; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Estrus;

1976
Audiogenic seizures: relation to age and mechanisms of monoamine neurotransmission.
    Brain research, 1976, Apr-16, Volume: 106, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Aging; Animals; Benserazide; Brain; Catecholamines; Dihyd

1976
Muscle stiffness and continuous electromyographic activity in old rats; an animal model for spasticity?
    Neuroscience, 1992, Volume: 51, Issue:1

    Topics: Aging; Animals; Atrophy; Baclofen; Benserazide; Drug Combinations; Electromyography; Female; Levodop

1992