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benserazide and Aggression

benserazide has been researched along with Aggression in 9 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"Experimental bruxism, audible, nonfunctional grinding or clenching of the teeth, was provoked in aggressive animals by drugs affecting central dopaminergic systems."1.26Experimental aggression and bruxism in rats. ( Pohto, P, 1979)
" Repeated or chronic administration of this metal in man or animals is known to result in a brain dopamine and/or serotonin deficit commensurate with the clinical manifestations of bradykinesia and dystonia."1.25Behavioral effects in rats following intrastriatal microinjection of manganese. ( Barbeau, A; Inoue, N; Tsukada, Y, 1975)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Onodera, K1
Kisara, K1
Ogura, Y1
Pohto, P1
Inoue, N1
Tsukada, Y1
Barbeau, A1
Benkert, O1
Renz, A1
Matussek, N1
Papeschi, R1
Hodge, GK1
Butcher, LL1
Kulkarni, AS2
Rahwan, RG1
Bocknik, SE2
Patni, SK1
Dandiya, PC1

Other Studies

9 other studies available for benserazide and Aggression

ArticleYear
Effect of 5-hydroxytryptophan on muricide response induced by thiamine deficiency.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 240, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Benserazide; Drug Interactions; Fenclonine; Humans; Male;

1979
Experimental aggression and bruxism in rats.
    Acta odontologica Scandinavica, 1979, Volume: 37, Issue:2

    Topics: Aggression; Animals; Apomorphine; Benserazide; Bruxism; Ditiocarb; Electroshock; Humans; Iproniazid;

1979
Behavioral effects in rats following intrastriatal microinjection of manganese.
    Brain research, 1975, Sep-12, Volume: 95, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Benserazide; Calcium Chloride; Caudate Nucleus; Dose-Response

1975
Dopamine, noradrenaline and 5-hydroxy-trytamine in relation to motor activity, fighting and mounting behaviour. II. L-dopa and DL-threo-dihydroxyphenylserine in combination with Ro 4-4602 and parachlorophenylalanine.
    Neuropharmacology, 1973, Volume: 12, Issue:3

    Topics: Aggression; Animals; Benserazide; Brain; Catechols; Dihydroxyphenylalanine; Dopamine; Drug Interacti

1973
An investigation on the behavioral and hypothermic effects of yohimbine: interaction with drugs affecting central and peripheral monoamines.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:1

    Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Bens

1974
5-Hydroxytryptamine correlates of isolation-induced aggression in mice.
    European journal of pharmacology, 1974, Volume: 28, Issue:2

    Topics: Aggression; Animals; Benserazide; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Human

1974
Muricidal block induced by 5-hydroxytryptophan in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 201, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Amygdala; Animals; Avoidance Learning; Behavior, Animal; Benserazid

1973
Effect of a decarboxylase inhibitor (Ro 4-4602) on 5-HTP induced muricide blockade in rats.
    Neuropharmacology, 1974, Volume: 13, Issue:4

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, An

1974
Apomorphine induced biting and fighting behaviour in reserpinized rats and an approach to the mechanism of action.
    Life sciences, 1974, Feb-16, Volume: 14, Issue:4

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Chlorpromazine; Clonid

1974