benphothiamine has been researched along with Polyneuropathies in 3 studies
benfotiamine : A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.
Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Currently, there are only few pathogenetically oriented pharmacotherapies for DSPN, one of which is benfotiamine, a prodrug of thiamine with a high bioavailability and favourable safety profile." | 3.11 | BOND study: a randomised double-blind, placebo-controlled trial over 12 months to assess the effects of benfotiamine on morphometric, neurophysiological and clinical measures in patients with type 2 diabetes with symptomatic polyneuropathy. ( Al-Hasani, H; Bönhof, GJ; Herder, C; Icks, A; Knebel, B; Kuss, O; Reule, C; Roden, M; Sipola, G; Strassburger, K; Strom, A; Wollmann, JC; Ziegler, D, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bönhof, GJ | 1 |
| Sipola, G | 1 |
| Strom, A | 1 |
| Herder, C | 1 |
| Strassburger, K | 1 |
| Knebel, B | 1 |
| Reule, C | 1 |
| Wollmann, JC | 1 |
| Icks, A | 1 |
| Al-Hasani, H | 1 |
| Roden, M | 1 |
| Kuss, O | 1 |
| Ziegler, D | 2 |
| Stirban, OA | 1 |
| Zeller-Stefan, H | 1 |
| Schumacher, J | 1 |
| Gaus, W | 1 |
| Schuerholz, T | 1 |
| Pop-Busui, R | 1 |
| Kempler, P | 1 |
2 trials available for benphothiamine and Polyneuropathies
| Article | Year |
|---|---|
BOND study: a randomised double-blind, placebo-controlled trial over 12 months to assess the effects of benfotiamine on morphometric, neurophysiological and clinical measures in patients with type 2 diabetes with symptomatic polyneuropathy.
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Humans; Polyneuropathies; Qua | 2022 |
Treatment with benfotiamine in patients with diabetic sensorimotor polyneuropathy: A double-blind, randomized, placebo-controlled, parallel group pilot study over 12 months.
Topics: Diabetes Mellitus; Diabetic Neuropathies; Double-Blind Method; Humans; Pilot Projects; Polyneuropath | 2020 |
1 other study available for benphothiamine and Polyneuropathies
| Article | Year |
|---|---|
[Treatment of neuropathies].
Topics: Adjuvants, Immunologic; Adrenergic Uptake Inhibitors; Amines; Analgesics; Antioxidants; Capsaicin; C | 2010 |