benphothiamine has been researched along with Inflammation in 4 studies
benfotiamine : A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with type 2 diabetes and urinary albumin excretion in the high-normal and microalbuminuric range (15-300 mg/24h) were randomized to receive benfotiamine (n = 39) or placebo (n = 43)." | 2.77 | Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy. ( Alkhalaf, A; Bakker, SJ; Bilo, HJ; Gans, RO; Groenier, KH; Heeringa, P; Kleefstra, N; Navis, GJ; Schalkwijk, CG; Scheijen, JL, 2012) |
| "Neuropathic pain was induced by either ligation of left L5/L6 spinal nerves or administration of streptozotocin (50 mg/kg, i." | 1.33 | Benfotiamine relieves inflammatory and neuropathic pain in rats. ( Caram-Salas, NL; Granados-Soto, V; Medina-Santillán, R; Reyes-García, G; Rocha-González, HI; Sánchez-Ramírez, GM; Vidal-Cantú, GC, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Djedovic, N | 1 |
| Božić, I | 1 |
| Miljković, Đ | 1 |
| Lavrnja, I | 1 |
| Shoeb, M | 1 |
| Ramana, KV | 1 |
| Alkhalaf, A | 1 |
| Kleefstra, N | 1 |
| Groenier, KH | 1 |
| Bilo, HJ | 1 |
| Gans, RO | 1 |
| Heeringa, P | 1 |
| Scheijen, JL | 1 |
| Schalkwijk, CG | 1 |
| Navis, GJ | 1 |
| Bakker, SJ | 1 |
| Sánchez-Ramírez, GM | 1 |
| Caram-Salas, NL | 1 |
| Rocha-González, HI | 1 |
| Vidal-Cantú, GC | 1 |
| Medina-Santillán, R | 1 |
| Reyes-García, G | 1 |
| Granados-Soto, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of De-Novo Algorithm and Formula in the Treatment of Patients With Intractable Chronic Craniofacial Neuralgia, or Chronic Migraine Headaches.[NCT03220113] | Phase 1/Phase 2 | 100 participants (Anticipated) | Interventional | 2017-07-01 | Recruiting | ||
| A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318] | Phase 4 | 86 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for benphothiamine and Inflammation
| Article | Year |
|---|---|
Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.
Topics: Aged; Biomarkers; Cell Adhesion Molecules; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endoth | 2012 |
3 other studies available for benphothiamine and Inflammation
| Article | Year |
|---|---|
Benfotiamine Reduces Dendritic Cell Inflammatory Potency.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Dendritic Cells; Inflammation; Inflammation Medi | 2021 |
Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Adhesion; Cell Death; Cell Line; Cyclooxyg | 2012 |
Benfotiamine relieves inflammatory and neuropathic pain in rats.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Diabetes Mellitus, Experimental; Dose-Respons | 2006 |