benphothiamine has been researched along with Hyperglycemia, Postprandial in 12 studies
benfotiamine : A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.
Hyperglycemia, Postprandial: Abnormally high BLOOD GLUCOSE level after a meal.
Excerpt | Relevance | Reference |
---|---|---|
" We aimed at investigating whether pulsed exposure to different glucose concentrations influences apoptosis in human retinal pericytes (HRP) versus bovine retinal pericytes (BRP), with consequences on the onset of diabetic retinopathy, and the possible protective role of thiamine." | 3.75 | Different apoptotic responses of human and bovine pericytes to fluctuating glucose levels and protective role of thiamine. ( Beltramo, E; Berrone, E; Porta, M; Tarallo, S, 2009) |
"Male participants with and without type 1 diabetes were studied in the General Clinical Research Centre of the Albert Einstein College of Medicine." | 2.73 | Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes. ( Brownlee, M; Du, X; Edelstein, D, 2008) |
"Thirteen people with type 2 diabetes were given a heat-processed test meal with a high AGE content (HAGE; 15." | 2.72 | Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. ( Gawlowski, T; Götting, C; Horstmann, T; Kleesiek, K; Koschinsky, T; Mueller-Roesel, M; Negrean, M; Stirban, A; Stratmann, B; Tschoepe, D; Uribarri, J; Vlassara, H, 2006) |
"Hyperglycemia is a causal factor in the development of the vascular complications of diabetes." | 1.33 | Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose. ( Ape, AU; Beltramo, E; Berrone, E; Porta, M; Solimine, C, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 7 (58.33) | 29.6817 |
2010's | 4 (33.33) | 24.3611 |
2020's | 1 (8.33) | 2.80 |
Authors | Studies |
---|---|
Yako, H | 1 |
Niimi, N | 1 |
Kato, A | 1 |
Takaku, S | 1 |
Tatsumi, Y | 1 |
Nishito, Y | 1 |
Kato, K | 1 |
Sango, K | 1 |
Stirban, A | 2 |
Pop, A | 1 |
Fischer, A | 1 |
Heckermann, S | 1 |
Tschoepe, D | 2 |
Du, X | 2 |
Edelstein, D | 2 |
Brownlee, M | 2 |
Beltramo, E | 3 |
Berrone, E | 3 |
Tarallo, S | 2 |
Porta, M | 3 |
Nizheradze, K | 1 |
Balakumar, P | 1 |
Rohilla, A | 1 |
Krishan, P | 1 |
Solairaj, P | 1 |
Thangathirupathi, A | 1 |
Engelen, L | 1 |
Stehouwer, CD | 1 |
Schalkwijk, CG | 1 |
Teodoro, JS | 1 |
Gomes, AP | 1 |
Varela, AT | 1 |
Duarte, FV | 1 |
Rolo, AP | 1 |
Palmeira, CM | 1 |
Hammes, HP | 1 |
Taguchi, T | 1 |
Matsumura, T | 1 |
Ju, Q | 1 |
Lin, J | 1 |
Bierhaus, A | 1 |
Nawroth, P | 1 |
Hannak, D | 1 |
Neumaier, M | 1 |
Bergfeld, R | 1 |
Giardino, I | 1 |
Obrenovich, ME | 1 |
Monnier, VM | 1 |
Solimine, C | 1 |
Ape, AU | 1 |
Negrean, M | 1 |
Stratmann, B | 1 |
Gawlowski, T | 1 |
Horstmann, T | 1 |
Götting, C | 1 |
Kleesiek, K | 1 |
Mueller-Roesel, M | 1 |
Koschinsky, T | 1 |
Uribarri, J | 1 |
Vlassara, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Role of the Glucosamine Pathway and Reactive Oxygen Species in the Pathogenesis of Diabetic Complications[NCT00703989] | 21 participants (Actual) | Interventional | 2005-02-28 | Completed | |||
A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318] | Phase 4 | 86 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
Effects of a Chronical Treatment With Benfotiamine in People With Type 2 Diabetes Mellitus on Pre- and Postprandial Endothelial Function, as Well as on the Function of the Autonomic Nervous System[NCT00446810] | Phase 4 | 30 participants (Anticipated) | Interventional | 2007-09-30 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for benphothiamine and Hyperglycemia, Postprandial
Article | Year |
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The multifaceted therapeutic potential of benfotiamine.
Topics: Animals; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Ag | 2010 |
Current therapeutic interventions in the glycation pathway: evidence from clinical studies.
Topics: Animals; Atherosclerosis; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathie | 2013 |
3 trials available for benphothiamine and Hyperglycemia, Postprandial
Article | Year |
---|---|
Variability of skin autofluorescence measurement over 6 and 12 weeks and the influence of benfotiamine treatment.
Topics: Adult; Aged; Chelating Agents; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus, Type 2 | 2013 |
Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Cytochrome P-450 Enzyme System; Diabe | 2008 |
Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes.
Topics: Adjuvants, Immunologic; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; En | 2006 |
7 other studies available for benphothiamine and Hyperglycemia, Postprandial
Article | Year |
---|---|
Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Survival; Citric Acid Cycle; Diabetic Nephropathies | 2021 |
Different apoptotic responses of human and bovine pericytes to fluctuating glucose levels and protective role of thiamine.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cattle; Cell Line; Cells, Cultured; Di | 2009 |
Thiamine and benfotiamine prevent apoptosis induced by high glucose-conditioned extracellular matrix in human retinal pericytes.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Adhesion; Cell Proliferation; Cells, Cultured; Cytopr | 2009 |
Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.
Topics: Azaserine; Diabetes Mellitus; Glucose; Glycolysis; Hep G2 Cells; Hexosamines; Humans; Hyperglycemia; | 2013 |
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.
Topics: Animals; Cattle; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium | 2003 |
Vitamin B1 blocks damage caused by hyperglycemia.
Topics: Aging; Animals; Cattle; Diabetic Angiopathies; Glucose Intolerance; Glycation End Products, Advanced | 2003 |
Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.
Topics: Aldehyde Reductase; Animals; Cattle; Cell Culture Techniques; Chelating Agents; Diabetic Retinopathy | 2006 |