Page last updated: 2024-10-23

benphothiamine and Disease Models, Animal

benphothiamine has been researched along with Disease Models, Animal in 10 studies

benfotiamine : A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The neurodegeneration of Alzheimer's disease (AD) affects not only brain structures associate with cognition early in the progression of the disease, but other areas such as the hypothalamus, a region involved in the control of metabolism and appetite."1.72Benfotiamine protects against hypothalamic dysfunction in a STZ-induced model of neurodegeneration in rats. ( Cardinali, CAEF; Donato, J; Gonçalves, AC; Guerra-Shinohara, EM; Kleinridders, A; Leboucher, A; Lima, GCA; Moraes, RCM; Portari, GV; Torrão, ADS, 2022)
" The present data suggest that thiamine precursors with high bioavailability might be useful as a complementary therapy in several neuropsychiatric disorders."1.46Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels. ( Anthony, DC; Bazhenova, N; Bettendorff, L; Caron, N; Coumans, B; Gorlova, A; Lakaye, B; Malgrange, B; Markova, N; Pavlov, D; Sambon, M; Shevtsova, E; Strekalova, T; Svistunov, A; Vignisse, J; Wins, P, 2017)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Yako, H1
Niimi, N1
Kato, A1
Takaku, S1
Tatsumi, Y1
Nishito, Y1
Kato, K1
Sango, K1
Moraes, RCM1
Lima, GCA1
Cardinali, CAEF1
Gonçalves, AC1
Portari, GV2
Guerra-Shinohara, EM1
Leboucher, A1
Donato, J1
Kleinridders, A1
Torrão, ADS1
Ahmed, LA1
Hassan, OF1
Galal, O1
Mansour, DF1
El-Khatib, A1
Vignisse, J3
Sambon, M1
Gorlova, A1
Pavlov, D1
Caron, N1
Malgrange, B1
Shevtsova, E1
Svistunov, A2
Anthony, DC2
Markova, N2
Bazhenova, N2
Coumans, B1
Lakaye, B1
Wins, P1
Strekalova, T2
Bettendorff, L3
Tapias, V1
Jainuddin, S1
Ahuja, M1
Stack, C1
Elipenahli, C1
Gerges, M1
Starkova, N1
Xu, H1
Starkov, AA1
Hushpulian, DM1
Smirnova, NA1
Gazaryan, IG1
Kaidery, NA1
Wakade, S1
Calingasan, NY1
Thomas, B1
Gibson, GE1
Dumont, M1
Beal, MF1
Ovidio, PP1
Deminice, R1
Jordão, AA1
Lesch, KP1
Katare, RG1
Caporali, A1
Oikawa, A1
Meloni, M1
Emanueli, C1
Madeddu, P1
Karachalias, N1
Babaei-Jadidi, R1
Rabbani, N1
Thornalley, PJ1
Wu, S1
Ren, J1

Other Studies

10 other studies available for benphothiamine and Disease Models, Animal

ArticleYear
Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions.
    Scientific reports, 2021, 09-23, Volume: 11, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Survival; Citric Acid Cycle; Diabetic Nephropathies

2021
Benfotiamine protects against hypothalamic dysfunction in a STZ-induced model of neurodegeneration in rats.
    Life sciences, 2022, Oct-01, Volume: 306

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Rats; Streptozocin; Thiamine

2022
Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, in isoproterenol-induced myocardial infarction in rats.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Animals; Biomarkers; Cardiotoxins; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; H

2020
Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels.
    Molecular and cellular neurosciences, 2017, Volume: 82

    Topics: Animals; Dentate Gyrus; Disease Models, Animal; Glycogen Synthase Kinase 3; Hippocampus; Male; Mice,

2017
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
    Human molecular genetics, 2018, 08-15, Volume: 27, Issue:16

    Topics: Amyloid beta-Peptides; Animals; Antioxidant Response Elements; Brain; Disease Models, Animal; Humans

2018
Protective effect of treatment with thiamine or benfotiamine on liver oxidative damage in rat model of acute ethanol intoxication.
    Life sciences, 2016, Oct-01, Volume: 162

    Topics: Alcoholic Intoxication; Animals; Disease Models, Animal; Liver Diseases; Male; Oxidative Stress; Rat

2016
Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 04-03, Volume: 75

    Topics: Animals; Avoidance Learning; Brain; Cognition Disorders; Conditioning, Psychological; Disease Models

2017
Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1-mediated survival pathway.
    Circulation. Heart failure, 2010, Volume: 3, Issue:2

    Topics: Analysis of Variance; Animals; Apoptosis; Blood Flow Velocity; Blotting, Western; Carrier Proteins;

2010
Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes.
    Diabetologia, 2010, Volume: 53, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Kidney Glo

2010
Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha.
    Neuroscience letters, 2006, Feb-13, Volume: 394, Issue:2

    Topics: Adjuvants, Immunologic; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Experimenta

2006