benphothiamine and Chronic Kidney Failure studies

benphothiamine and Chronic Kidney Failure

benfotiamine : A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.

Research Excerpts

Excerpt	Relevance	Reference
"The pharmacokinetic parameters AUC0-24h, Cmax and tmax of the benfotiamin group in whole blood and plasma exceeded significantly those in the TN group."	2.69	Alteration of thiamine pharmacokinetics by end-stage renal disease (ESRD). ( Bitsch, R; Frank, T; Maiwald, J; Stein, G, 1999)
"In the ESRD patients, after 24 h, the mean TDP concentration in erythrocytes increased from 158."	2.69	High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. ( Bitsch, R; Frank, T; Maiwald, J; Stein, G, 2000)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	2 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

2 (66.67)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Schupp, N	1
Dette, EM	1
Schmid, U	1
Bahner, U	1
Winkler, M	1
Heidland, A	1
Stopper, H	1
Frank, T	2
Bitsch, R	2
Maiwald, J	2
Stein, G	2

Studies

Schupp, N

Dette, EM

Schmid, U

Bahner, U

Winkler, M

Heidland, A

Stopper, H

Frank, T

Bitsch, R

Maiwald, J

Stein, G

Trials

3 trials available for benphothiamine and Chronic Kidney Failure

Article	Year
Benfotiamine reduces genomic damage in peripheral lymphocytes of hemodialysis patients. Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:3 Topics: Aged; Antimutagenic Agents; Cell Separation; Cells, Cultured; Diabetic Nephropathies; DNA Damage; Fe	2008
Alteration of thiamine pharmacokinetics by end-stage renal disease (ESRD). International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:9 Topics: Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Kidney Failure, Chronic;	1999
High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. European journal of clinical pharmacology, 2000, Volume: 56, Issue:3 Topics: Administration, Oral; Adult; Area Under Curve; Erythrocytes; Female; Humans; Kidney Failure, Chronic	2000

Article

Year

Benfotiamine reduces genomic damage in peripheral lymphocytes of hemodialysis patients.

Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:3

Topics: Aged; Antimutagenic Agents; Cell Separation; Cells, Cultured; Diabetic Nephropathies; DNA Damage; Fe

2008

Alteration of thiamine pharmacokinetics by end-stage renal disease (ESRD).

International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:9

Topics: Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Kidney Failure, Chronic;

1999

High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine.

European journal of clinical pharmacology, 2000, Volume: 56, Issue:3

Topics: Administration, Oral; Adult; Area Under Curve; Erythrocytes; Female; Humans; Kidney Failure, Chronic

2000