Page last updated: 2024-10-23

benphothiamine and Albuminuria

benphothiamine has been researched along with Albuminuria in 4 studies

benfotiamine : A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
" Thiamine was found to be beneficial for reduction in albuminuria in a single study; however, there was lack of any improvement in kidney function or blood pressure following the use of vitamin B preparations used alone or in combination."4.91Vitamin B and its derivatives for diabetic kidney disease. ( Gor, D; Rangoonwala, AN; Raval, AD; Thakker, D; Walia, R, 2015)
"Patients with type 2 diabetes and UAE equivalent to 15-300 mg/24 h, despite ACE inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs), were randomly assigned to 12 weeks of benfotiamine (900 mg/day) (n = 39) or placebo (n = 43)."2.75A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy. ( Achenbach, U; Alkhalaf, A; Bakker, SJ; Bilo, HJ; Gans, RO; Kleefstra, N; Klooster, A; Mijnhout, GS; Navis, GJ; Slingerland, RJ; van Oeveren, W, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raval, AD1
Thakker, D1
Rangoonwala, AN1
Gor, D1
Walia, R1
Alkhalaf, A1
Klooster, A1
van Oeveren, W1
Achenbach, U1
Kleefstra, N1
Slingerland, RJ1
Mijnhout, GS1
Bilo, HJ1
Gans, RO1
Navis, GJ1
Bakker, SJ1
Kihm, LP1
Müller-Krebs, S1
Klein, J1
Ehrlich, G1
Mertes, L1
Gross, ML1
Adaikalakoteswari, A1
Thornalley, PJ2
Hammes, HP1
Nawroth, PP1
Zeier, M1
Schwenger, V1
Babaei-Jadidi, R1
Karachalias, N1
Ahmed, N1
Battah, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318]Phase 486 participants (Anticipated)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for benphothiamine and Albuminuria

ArticleYear
Vitamin B and its derivatives for diabetic kidney disease.
    The Cochrane database of systematic reviews, 2015, Jan-12, Volume: 1

    Topics: Albuminuria; Diabetic Nephropathies; Folic Acid; Humans; Pyridoxamine; Randomized Controlled Trials

2015

Trials

1 trial available for benphothiamine and Albuminuria

ArticleYear
A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy.
    Diabetes care, 2010, Volume: 33, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotens

2010

Other Studies

2 other studies available for benphothiamine and Albuminuria

ArticleYear
Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis.
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:5

    Topics: Albuminuria; Animals; Fibrosis; Glycation End Products, Advanced; Kidney; Male; Peritoneal Dialysis;

2011
Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine.
    Diabetes, 2003, Volume: 52, Issue:8

    Topics: Albuminuria; Animals; Chelating Agents; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dos

2003