benoxinate has been researched along with Pain in 14 studies
benoxinate: RN given refers to parent cpd; structure
oxybuprocaine : A benzoate ester in which 4-amino-3-butoxybenzoic acid and 2-(diethylamino)ethanol have combined to form the ester bond; an ester-based local anaesthetic (ester "caine") used especially in ophthalmology and otolaryngology.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two weeks before, a corneal ulcer was diagnosed, and oxybuprocaine 0." | 3.72 | Toxic keratopathy associated with abuse of low-dose anesthetic: a case report. ( Chen, HT; Chen, KH; Hsu, WM, 2004) |
| " After rats were injected intrathecally with proxymetacaine, oxybuprocaine, bupivacaine, and lidocane, dose-response curves were constructed." | 1.35 | Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats. ( Chen, YC; Chen, YW; Chu, CC; Hung, CH; Wang, JJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, CH | 2 |
| Wang, JJ | 2 |
| Chen, YC | 2 |
| Chu, CC | 2 |
| Chen, YW | 2 |
| Stanga, PE | 1 |
| Muqit, MM | 1 |
| Hsueh, MI | 1 |
| Kobayashi, T | 1 |
| Nishizawa, K | 1 |
| Ogura, K | 1 |
| SCHLEGEL, HE | 1 |
| SWAN, KC | 1 |
| Chen, HT | 1 |
| Chen, KH | 1 |
| Hsu, WM | 1 |
| Law, RW | 1 |
| Li, RT | 1 |
| Lam, DS | 1 |
| Lai, JS | 1 |
| Bracaglia, R | 1 |
| Fortunato, R | 1 |
| Gentileschi, S | 1 |
| Hagan, JC | 1 |
| Stolze, HH | 1 |
| Volprecht, A | 1 |
| Welter, U | 1 |
| Callear, AB | 1 |
| Virtanen, P | 1 |
| Huha, T | 1 |
| Spiritus, A | 1 |
| Huygens, M | 1 |
| Callebaut, F | 1 |
| Blaschke, V | 1 |
| Fuchs, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects on Betadine 5% Penetration When Using Lidocaine 2% Jelly Versus Topical Tetracaine 0.5% for Topical Phacoemulsification Cataract Surgery.[NCT00827073] | 40 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Within 3 hours from time of culture acquisition, the samples will be vortexed for 30 seconds and 100µl aliquots will be plated onto 5% sheep blood and chocolate agar plates. These plates will be incubated with 5% carbon dioxide at 35˚ C for 72 hours. After 72 hours all plates will be read for colony count and identification of all isolates will be performed using routine microbiological methods. The natural log of bacterial bacterial colony count will be used for the outcome measure. (NCT00827073)
Timeframe: (1) Pre-antibiotics swab, and (2) Post-study medication (pre surgery)
| Intervention | Ln(bacterial colony count) (Mean) |
|---|---|
| Tetracaine 0.5% Drop | -0.14 |
| Lidocaine 2% Jelly | -0.52 |
(NCT00827073)
Timeframe: (1) Pre-antibiotics swab and (2) Post-study medication (pre surgery)
| Intervention | bacterial spceies (Mean) | |
|---|---|---|
| pre number of bacterial spices | post surgery number of bacterial speices | |
| Lidocaine 2% Jelly | 1 | 1 |
| Tetracaine 0.5% Drop | 1 | 1 |
5 trials available for benoxinate and Pain
| Article | Year |
|---|---|
Is instillation of anesthetic gel necessary in flexible cystoscopic examination? A prospective randomized study.
Topics: Administration, Intravesical; Anesthetics, Local; Cystoscopy; Gels; Humans; Lidocaine; Lubrication; | 2003 |
Efficacy of pressure topical anaesthesia in punctal occlusion by diathermy.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Dry Eye Syndromes; Electrocoagulation; Eyelids; Female | 2005 |
The effect of temperature on the discomfort caused by topical local anaesthesia.
Topics: Aged; Anesthetics, Local; Humans; Lidocaine; Middle Aged; Pain; Pain Measurement; Procaine; Temperat | 1995 |
Pain in scleral pocket incision cataract surgery using topical and peribulbar anesthesia.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; A | 1998 |
Topical anesthesia without intracameral lidocaine in cataract surgery.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Blepharospasm; Cataract Extraction; Humans; Hypnotics a | 2000 |
9 other studies available for benoxinate and Pain
| Article | Year |
|---|---|
Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats.
Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Injections, Spina | 2009 |
Retinal laser photocoagulation, anaesthesia, and pain responses.
Topics: Anesthesia, Conduction; Anesthetics, Local; Humans; Laser Coagulation; Pain; Procaine; Retina | 2010 |
Clonidine as adjuvant for oxybuprocaine, bupivacaine or dextrorphan has a significant peripheral action in intensifying and prolonging analgesia in response to local dorsal cutaneous noxious pinprick in rats.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesia; Anesthetics, Local; Animals; Area Under | 2011 |
Benoxinate (dorsacaine) for rapid corneal anesthesia.
Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics; Anesthetics, Local; Co | 1954 |
Toxic keratopathy associated with abuse of low-dose anesthetic: a case report.
Topics: Anesthetics, Local; Corneal Ulcer; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Ophth | 2004 |
A little trick to reduce pain at the moment of blepharoplasty stitch removal.
Topics: Anesthetics, Local; Blepharoplasty; Humans; Pain; Procaine; Sutures | 2006 |
Misuse of topical ocular anesthetics.
Topics: Aged; Blindness; Eye; Female; Humans; Ophthalmic Solutions; Pain; Procaine | 1981 |
Topical anesthetic induced pain as a diagnostic tool for kerato conjunctivitis sicca (KCS).
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum | 1994 |
Periorbital allergic contact dermatitis from oxybuprocaine.
Topics: Aged; Anesthetics, Local; Dermatitis, Allergic Contact; Diagnosis, Differential; Facial Dermatoses; | 2001 |